{
    "uniprot_canonical_ac": "A2AS55-1", 
    "publication_count": 2, 
    "reported_interactions": 0, 
    "record_type": "protein", 
    "predicted_glycosites": 0, 
    "protein_names_refseq": "ankyrin repeat domain-containing protein 16 isoform 1; ankyrin repeat domain-containing protein 16", 
    "refseq_ac": "NP_796242.2", 
    "reported_n_glycosites": 0, 
    "refseq_name": "ankyrin repeat domain-containing protein 16 isoform 1", 
    "record_id": "A2AS55-1", 
    "protein_names_uniprotkb": "Ankyrin repeat domain-containing protein 16; Ankyrin repeat domain-containing protein 16", 
    "pathway": " (mmu:320816)", 
    "function": "Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity (PubMed:29769718). Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides (PubMed:29769718)., [UniProtKB]; Results identify an amino-acid-accepting co-regulator of tRNA synthetase editing, ANKRD16, as a new layer of the machinery that is essential to the prevention of severe pathologies that arise from defects in editing Erratum:[Nature. 2018 Aug;560(7720):E35. PMID: 29925958], [RefSeq]", 
    "protein_name": "Ankyrin repeat domain-containing protein 16", 
    "reported_mutagensis": 3, 
    "reported_phosphosites": 0, 
    "reported_o_glycosites_with_glycan": 0, 
    "tax_id": 10090, 
    "organism": "Mus musculus", 
    "disease": "", 
    "reported_glycation": 0, 
    "reported_snv": 0, 
    "mass": 39776.0, 
    "gene_names_uniprotkb": "Ankrd16", 
    "reported_n_glycosites_with_glycan": 0, 
    "reported_o_glycosites": 0, 
    "gene_names_refseq": "2810455F06Rik; AI646698; D430029B21Rik; Ankrd16", 
    "gene_name": "Ankrd16"
}