{
    "uniprot_canonical_ac": "A2AP18-1", 
    "publication_count": 9, 
    "reported_interactions": 0, 
    "record_type": "protein", 
    "predicted_glycosites": 0, 
    "protein_names_refseq": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 isoform a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 isoform b; phospholipase C-like protein 4; phosphoinositide phospholipase C-eta-2; phosphoinositide phospholipase C-like 4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2", 
    "refseq_ac": "NP_780765.2", 
    "reported_n_glycosites": 0, 
    "refseq_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 isoform a", 
    "record_id": "A2AP18-1", 
    "protein_names_uniprotkb": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2; Phosphoinositide phospholipase C; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2; 3.1.4.11; PLC-L4; PLC-eta2; Phosphoinositide phospholipase C-eta-2; Phosphoinositide phospholipase C-like 4; Phospholipase C-eta-2; Phospholipase C-like protein 4", 
    "pathway": " (mmu:269615); Synthesis of IP3 and IP4 in the cytosol (R-MMU-1855204)", 
    "function": "Molecular cloning of PLC-eta1 and PLC-eta2., [RefSeq]; Molecular cloning of PLC-eta1 and PLC-eta2., [RefSeq]; PLC(eta)2 is a neuron-specific isozyme that may be important for the formation and/or maintenance of the neuronal network in the postnatal brain, [RefSeq]; PLC(eta)2 is a neuron-specific isozyme that may be important for the formation and/or maintenance of the neuronal network in the postnatal brain, [RefSeq]; PLCeta2 exhibited a dynamic expression pattern during postnatal retinal development, strongly suggesting that this isozyme might be involved in the development and maturation of the retina., [RefSeq]; PLCeta2 exhibited a dynamic expression pattern during postnatal retinal development, strongly suggesting that this isozyme might be involved in the development and maturation of the retina., [RefSeq]; The molecular cloning and sequencing of phospholipase C eta2 are reported., [RefSeq]; The molecular cloning and sequencing of phospholipase C eta2 are reported., [RefSeq]; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This phospholipase activity is very sensitive to calcium. May be important for formation and maintenance of the neuronal network in the postnatal brain., [UniProtKB]; The role of PLCeta2 in neuritogenesis was assessed during retinoic acid (RA)-induced Neuro2A cell differentiation, [RefSeq]; The role of PLCeta2 in neuritogenesis was assessed during retinoic acid (RA)-induced Neuro2A cell differentiation, [RefSeq]", 
    "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2; Phosphoinositide phospholipase C", 
    "reported_mutagensis": 1, 
    "reported_phosphosites": 8, 
    "reported_o_glycosites_with_glycan": 0, 
    "tax_id": 10090, 
    "organism": "Mus musculus", 
    "disease": "", 
    "reported_glycation": 0, 
    "reported_snv": 0, 
    "mass": 164297.0, 
    "gene_names_uniprotkb": "Plch2; Plcl4", 
    "reported_n_glycosites_with_glycan": 0, 
    "reported_o_glycosites": 0, 
    "gene_names_refseq": "A930027K05Rik; Pl; Plc-eta2; PLCe; PLCeta2; Plcl4; Plch2", 
    "gene_name": "Plch2"
}