{ "uniprot_canonical_ac": "A2AED3-1", "ptm_annotation": [], "sequence": { "header": "sp|A2AED3-1|FNDC7_MOUSE Isoform 1 of Fibronectin type III domain-containing protein 7 OS=Mus musculus OX=10090 GN=Fndc7 PE=2 SV=1 CANONICAL=A2AED3-1", "length": 737, "sequence": "MAGRPEKCFSLIRFTLLCLKMVISSKTAPEIPTIDQAYSKISNSITVEWTTVPGATSYLLTAEDGNTIIETTVANSPGTVTGLKAATLYQITIRSISASGQSQASSPKQAKTVLAAPVLEVSSPSPDSILVSWDAVYMAIGFSVSVMRANGLGRIWKENTTNTSLTFSSLDAGTLYTIKAYAWNANGIPGDDSTRNQRTSPRAPANIQVFFDSGALKASVSWTPTEGAFNYTVVASSDSSQRSCSTTLSSCSISSLQCGTEYLISVSANNDAGSSKSCSAPTLKTVACAPGRVMIQEEPPGHLSVAWSNVELGDYYVAFVKSDDGLEVHCNTSLTQCNFLSECGFTYFISVFAYNKAGQSPLGDVFNYTTAPCCPNDISPVLVSSDRVEIAWSPVRGAELYETKAIAGYSIVECNDTAPACTLSALDCDTKYNVTVYSFSEVRGSNLSCSSHFITTAPCSPEIKNISKDAFSMINVHWRSTNEGATYTVTAQGKKGLFQCSSTGETCRMGGLPCGSMFSVTAVAETQAGKSLPSYSVPLETVPCCPAGLTAAQVTQSIINVSWTAGAVAQTYAAVLESYIGQSKCHTHQNHCLLGCITCGINYTVALKAISSTGLTADCAYQSYSSSVCCPLGVKLYRLGPNGIRIYWRASRGAANYSTDLYGSKGIFTCAPHAGLSFCDITNIPCGDVYTVMVSPVAETGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNDTASPR" }, "uniprot_id": "FNDC7_MOUSE", "enzyme_annotation": [], "glycation": [], "keywords": [ "glycoprotein", "predicted.uniprotkb_gly" ], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AED3", "id": "A2AED3", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "publication": [], "uniprot_ac": "A2AED3", "site_annotation": [ { "end_pos": 161, "annotation": "n_glycosylation_sequon", "start_pos": 159 }, { "end_pos": 164, "annotation": "n_glycosylation_sequon", "start_pos": 162 }, { "end_pos": 232, "annotation": "n_glycosylation_sequon", "start_pos": 230 }, { "end_pos": 333, "annotation": "n_glycosylation_sequon", "start_pos": 331 }, { "end_pos": 369, "annotation": "n_glycosylation_sequon", "start_pos": 367 }, { "end_pos": 417, "annotation": "n_glycosylation_sequon", "start_pos": 415 }, { "end_pos": 435, "annotation": "n_glycosylation_sequon", "start_pos": 433 }, { "end_pos": 448, "annotation": "n_glycosylation_sequon", "start_pos": 446 }, { "end_pos": 467, "annotation": "n_glycosylation_sequon", "start_pos": 465 }, { "end_pos": 562, "annotation": "n_glycosylation_sequon", "start_pos": 560 }, { "end_pos": 604, "annotation": "n_glycosylation_sequon", "start_pos": 602 }, { "end_pos": 658, "annotation": "n_glycosylation_sequon", "start_pos": 656 }, { "end_pos": 733, "annotation": "n_glycosylation_sequon", "start_pos": 731 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2AED3#A2AED3-1", "isoform_ac": "A2AED3-1", "locus": { "end_pos": 108856370, "strand": "+", "start_pos": 108889706, "chromosome": "3", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000102620", "id": "ENSMUST00000102620", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000099680", "id": "ENSMUSP00000099680", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2AED3-1|FNDC7_MOUSE Isoform 1 of Fibronectin type III domain-containing protein 7 OS=Mus musculus OX=10090 GN=Fndc7 PE=2 SV=1 CANONICAL=A2AED3-1", "length": 737, "sequence": "MAGRPEKCFSLIRFTLLCLKMVISSKTAPEIPTIDQAYSKISNSITVEWTTVPGATSYLLTAEDGNTIIETTVANSPGTVTGLKAATLYQITIRSISASGQSQASSPKQAKTVLAAPVLEVSSPSPDSILVSWDAVYMAIGFSVSVMRANGLGRIWKENTTNTSLTFSSLDAGTLYTIKAYAWNANGIPGDDSTRNQRTSPRAPANIQVFFDSGALKASVSWTPTEGAFNYTVVASSDSSQRSCSTTLSSCSISSLQCGTEYLISVSANNDAGSSKSCSAPTLKTVACAPGRVMIQEEPPGHLSVAWSNVELGDYYVAFVKSDDGLEVHCNTSLTQCNFLSECGFTYFISVFAYNKAGQSPLGDVFNYTTAPCCPNDISPVLVSSDRVEIAWSPVRGAELYETKAIAGYSIVECNDTAPACTLSALDCDTKYNVTVYSFSEVRGSNLSCSSHFITTAPCSPEIKNISKDAFSMINVHWRSTNEGATYTVTAQGKKGLFQCSSTGETCRMGGLPCGSMFSVTAVAETQAGKSLPSYSVPLETVPCCPAGLTAAQVTQSIINVSWTAGAVAQTYAAVLESYIGQSKCHTHQNHCLLGCITCGINYTVALKAISSTGLTADCAYQSYSSSVCCPLGVKLYRLGPNGIRIYWRASRGAANYSTDLYGSKGIFTCAPHAGLSFCDITNIPCGDVYTVMVSPVAETGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNDTASPR" } }, { "url": "https://www.uniprot.org/uniprot/A2AED3#A2AED3-3", "isoform_ac": "A2AED3-3", "locus": {}, "sequence": { "header": "sp|A2AED3-3|FNDC7_MOUSE Isoform 3 of Fibronectin type III domain-containing protein 7 OS=Mus musculus OX=10090 GN=Fndc7 PE=2 SV=1 CANONICAL=A2AED3-1", "length": 324, "sequence": "MAIGFSVSVMRANGLGRIWKENTTNTSLTFSSLDAGTLYTIKAYAWNANGIPGDDSTRNQRTSPRAPANIQVFFDSGALKASVSWTPTEGAFNYTVVASSDSSQRSCSTTLSSCSISSLQCGTEYLISVSANNDAGSSKSCSAPTLKTVACAPGRVMIQEEPPGHLSVAWSNVELGDYYVAFVKSDDGLEVHCNTSLTQCNFLSECGFTYFISVFAYNKAGQSPLGDVFNYTTAPCCPNDISPVLVSSDRVEIAWSPVRGAELYETKAIAGYSIVECNDTAPACTLSALDCDTKYNVTVYSFSEVRGSNLSCSSHFITTGMVLL" } }, { "url": "https://www.uniprot.org/uniprot/A2AED3#A2AED3-4", "isoform_ac": "A2AED3-4", "locus": { "end_pos": 108856370, "strand": "+", "start_pos": 108889706, "chromosome": "3", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000053065", "id": "ENSMUST00000053065", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000051172", "id": "ENSMUSP00000051172", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2AED3-4|FNDC7_MOUSE Isoform 4 of Fibronectin type III domain-containing protein 7 OS=Mus musculus OX=10090 GN=Fndc7 PE=2 SV=1 CANONICAL=A2AED3-1", "length": 651, "sequence": "MAGRPEKCFSLIRFTLLCLKMVISSKTAPEIPTIDQAYSKISNSITVEWTTVPGATSYLLTAEDGNTIIETTVANSPGTVTGLKAATLYQITIRSISASGQSQASSPKQAKTVLAAPVLEVSSPSPDSILVSWDAVYMAIGFSVSVMRANGLGRIWKENTTNTSLTFSSLDAGTLYTIKAYAWNANGIPGDDSTRNQRTIACAPGRVMIQEEPPGHLSVAWSNVELGDYYVAFVKSDDGLEVHCNTSLTQCNFLSECGFTYFISVFAYNKAGQSPLGDVFNYTTAPCCPNDISPVLVSSDRVEIAWSPVRGAELYETKAIAGYSIVECNDTAPACTLSALDCDTKYNVTVYSFSEVRGSNLSCSSHFITTAPCSPEIKNISKDAFSMINVHWRSTNEGATYTVTAQGKKGLFQCSSTGETCRMGGLPCGSMFSVTAVAETQAGKSLPSYSVPLETVPCCPAGLTAAQVTQSIINVSWTAGAVAQTYAAVLESYIGQSKCHTHQNHCLLGCITCGINYTVALKAISSTGLTADCAYQSYSSSVCCPLGVKLYRLGPNGIRIYWRASRGAANYSTDLYGSKGIFTCAPHAGLSFCDITNIPCGDVYTVMVSPVAETGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNDTASPR" } }, { "url": "https://www.uniprot.org/uniprot/A2AED3#J3QMB8-1", "isoform_ac": "J3QMB8-1", "locus": { "end_pos": 108856370, "strand": "+", "start_pos": 108889706, "chromosome": "3", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000180063", "id": "ENSMUST00000180063", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000136215", "id": "ENSMUSP00000136215", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|J3QMB8-1|FNDC7_MOUSE Computationally mapped isoform of Fibronectin type III domain-containing protein 7 OS=Mus musculus OX=10090 GN=Fndc7 PE=2 SV=1 CANONICAL=A2AED3-1", "length": 737, "sequence": "MAGRPEKCFSLIRFTLLCLKMVRSGKRSPEIPTIDQAYSKISNSITVEWTTVPGATSYLLTAEDGNTIIETTVANSPGTVTGLKAATLYQITIRSISASGQSQASSPKQAKTVLAAPVLEVSSPSPDSILVSWDAVYMAIGFSVSVMRANGLGRIWKENTTNTSLTFSSLDAGTLYTIKAYAWNANGIPGDDSTRNQRTSPRAPANIQVFFDSGALKASVSWTPTEGAFNYTVVASSDSSQRSCSTTLSSCSISSLQCGTEYLISVSANNDAGSSKSCSAPTLKTVACAPGRVMIQEEPPGHLSVAWSNVELGDYYVAFVKSDDGLEVHCNTSLTQCNFLSECGFTYFISVFAYNKAGQSPLGDVFNYTTAPCCPNDISPVLVSSDRVEIAWSPVRGAELYETKAIAGYSIVECNDTAPACTLSALDCDTKYNVTVYSFSEVRGSNLSCSSHFITTAPCSPEIKNISKDAFSMINVHWRSTNEGATYTVTAQGKKGLFQCSSTGETCRMGGLPCGSMFSVTAVAETQAGKSLPSYSVPLETVPCCPAGLTAAQVTQSIINVSWTAGAVAQTYAAVLESYIGQSKCHTHQNHCLLGCITCGINYTVALKAISSTGLTADCAYQSYSSSVCCPLGVKLYRLGPNGIRIYWRASRGAANYSTDLYGSKGIFTCAPHAGLSFCDITNIPCGDVYTVMVSPVAETGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNDTASPR" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:320181", "resource": "KEGG Pathway", "id": "mmu:320181", "name": "" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZJV4-1", "protein_name": "Similar to RIKEN cDNA E230011A21 gene (Predicted), isoform CRA_a", "sequence": { "length": 737, "sequence": "MAGRPEKHLPLIRFTLLCLKMVISSKTAPEIPTIDQAYSKISNSITVEWTTVPGATSYLLTAEDGDTTIETTVANSPGTVTGLKAATLYQITIRSVSASGRSPASPPKQAKTVLAAPILEVSSPSPDSILVSWDAVYMAIGFSVSVMQANGLGRIWKENTTNTSLTFSSLDAGTLYTIKAYAWNANGIPGDDSTRNQRTSPRAPANIQVFFDSGALKASVSWTPSEGAFNYTVVAWSGSSQRSCSTALSSCSIGSLQCGTEYLISVSANNDAGCSKSSSAPTLKTVACAPGRVMIQEEPPGHLSVAWSNVELGDYYVAFVKSDDGLEVHCNTSLTQCNFLSECGFTYFISVFAYNKAGQSPLGDVFNYTTAPCCPSDISPVLVSSDRVEIAWSPVRGAELYETKAIAGYSVVACNDTAPACTLSALDCDTKYNVTVYSFSEVRGSNLSCSSHFITTAPCSPEIKNISKDAFSMINVHWRSTNEGATYTVTAQGKKGLFRCSSTGETCRMGGLPCGSVFSVTAVAETQAGKSLPSYSVPLETVPCCPAGLTAAQVTQSIINVSWTIGAVAQTYVTVLESYIGQSKCHTHQNHCLLGCIACGINYTVALKAISPTGLTADCAYQSYSSSVCCPLGVKLYRLGPNGIRIYWQASRGSANYSTDLYGSKGIFTCAPHTGLSFCDITNIPCGDVYTVMVSPVAETGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNDTVSPR" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/18551", "id": "18551", "database": "MGI" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q5VTL7-1", "protein_name": "Fibronectin type III domain-containing protein 7", "sequence": { "length": 733, "sequence": "MAGGRETCLPLIGFILICLKMVASAKSAPEIPTIDQAYSKLSNSITVEWATVPGATSYLLTAEDGDTVIETTVANSPGTVTGLKAATWYEITIRSISAAGRSQASPPKQAKTVLAAPILEVSSPSSDSILVQWEAVYMAIAFSVSIMRANGLGSIWKENTTNTSLTFTSLEAGTLYTIKAYAWNANRIPGDDSTCNQRTSPRAPANIQVSFDSGALKASFSWARAEGAFNYTVMALSDSSELTCSTTFSSCTISSLQCGTEYLISVLASNDAGSSKSSSAMTLKTVACAPGRVTIQEDPPGHLSVAWSSVDLGDYYVVFVKSDDGLEVHCNTSLTQCNFLSECGFTYFISVFVYNKAGQSPLGDIFNYTTAPCCPSDINPVLVSSDRVEIVWSPVRGAELYETKAVDGYNMVECNDTTPACTLSALECDTKYNITVYSFNEVRGSNMSCTPQFITTAPCSPEIKNVSRDAFSMINVHWRSTNDDATYTVTAQGEKGLYQCSSTGESCTMRGLPCGSVFSVTAVAETQAGRSLPSYSVPLETVPCCPTGLTVTQITQSVINVSWTIGRVAQTHVAVLESHTGQSKCHTHQNHCLLGCITCGINYTVTLKAISATGLTADCSYQSYFSGACCPLGVKLYRLGPNGIRIYWQASRGSANYSTDLYGSKGIFTCTPSAGLSFCDVTEIPCGDVYTVMVSPVAKTGLKLTFCPKKIYSVTCSGSTLGMVIYRGKRNEE" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/18551", "id": "18551", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159437.1", "ac": "NP_001159437.1", "name": "fibronectin type III domain-containing protein 7 isoform 2 precursor", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AED3", "id": "A2AED3", "database": "UniProtKB" } ], "name": "extracellular region", "id": "GO:0005576" } ], "total": 1, "name": "Cellular Component" } ] }, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AED3", "type": "synonym", "resource": "RefSeq", "name": "E230011A21Rik" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AED3", "type": "synonym", "resource": "RefSeq", "name": "Fndc7" }, { "url": "https://www.uniprot.org/uniprot/A2AED3", "type": "recommended", "resource": "UniProtKB", "name": "Fndc7" } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000045326", "id": "ENSMUSG00000045326", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "id": "cd00063", "database": "CDD" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/320181", "id": "320181", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "id": "IPR003961", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "id": "IPR013783", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "id": "IPR036116", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:320181", "id": "mmu:320181", "database": "KEGG Pathway" }, { "url": "http://www.informatics.jax.org/marker/MGI:2443535", "id": "2443535", "database": "MGI" }, { "url": "http://www.orthodb.org/?query=190531at2759", "id": "190531at2759", "database": "OrthoDB" }, { "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2AED3", "id": "PR_A2AED3", "database": "PRO" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001159437.1", "id": "NP_001159437.1", "database": "RefSeq" } ], "expression_disease": [], "glycosylation": [ { "residue": "Asn", "site_category": "predicted", "end_pos": 230, "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AED3#ptm_processing", "id": "A2AED3", "database": "UniProtKB" } ], "subtype": "", "relation": "attached", "start_pos": 230, "glytoucan_ac": "", "type": "N-linked" }, { "residue": "Asn", "site_category": "predicted", "end_pos": 433, "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AED3#ptm_processing", "id": "A2AED3", "database": "UniProtKB" } ], "subtype": "", "relation": "attached", "start_pos": 433, "glytoucan_ac": "", "type": "N-linked" } ], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 78141.0, "chemical_mass": 78141.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A2AED3", "name": "Fndc7", "locus": { "end_pos": 108853678, "strand": "-", "start_pos": 108890008, "chromosome": "3", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000045326", "id": "ENSMUSG00000045326", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A2AED3", "type": "recommended", "resource": "UniProtKB", "name": "Fibronectin type III domain-containing protein 7" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AED3", "type": "synonym", "resource": "RefSeq", "name": "fibronectin type III domain-containing protein 7 isoform 2 precursor" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AED3", "type": "synonym", "resource": "RefSeq", "name": "fibronectin type III domain-containing protein 7" } ] }