{
    "uniprot_canonical_ac": "A2A8T1-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A2A8T1-1|A2A8T1_MOUSE Isoform 1 of Cytochrome P450, family 4, subfamily a, polypeptide 32  OS=Mus musculus OX=10090 GN=Cyp4a32 PE=3 SV=1 CANONICAL=A2A8T1-1", 
        "length": 509, 
        "sequence": "MSVSALSPTRFADSLSGFLQVASVLGLLLLLVKAVQFYLHRKWLLKALQQFPSPPFHWFFGHEQFKGEQELKEVVSCIEHFPSAFPCWFWGSNAYLTVYDPDYMKVILGRSDPKANGIYRLLAPWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLAGQDSSIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYKTYLQAIGDLNNLFHSRVRNIFHQNDTIYRLSSNGRLAKQACQLAHDHTDGVIKMRKDQLQDEGELENIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLHFELLPDPTRVPEPLARIVLKSKNGIYLHLKKLH"
    }, 
    "uniprot_id": "A2A8T1_MOUSE", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                    "id": "A2A8T1", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/21677750", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "21677750"
                }
            ], 
            "title": "A conditional knockout resource for the genome-wide study of mouse gene function.", 
            "journal": "Nature", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093651.1", 
                    "id": "NP_001093651.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A", 
            "date": "2011"
        }
    ], 
    "uniprot_ac": "A2A8T1", 
    "site_annotation": [
        {
            "end_pos": 240, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 238
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A8T1#A2A8T1-1", 
            "isoform_ac": "A2A8T1-1", 
            "locus": {
                "end_pos": 115600975, 
                "strand": "-", 
                "start_pos": 115621599, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000084342", 
                        "id": "ENSMUST00000084342", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000081369", 
                        "id": "ENSMUSP00000081369", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A2A8T1-1|A2A8T1_MOUSE Isoform 1 of Cytochrome P450, family 4, subfamily a, polypeptide 32  OS=Mus musculus OX=10090 GN=Cyp4a32 PE=3 SV=1 CANONICAL=A2A8T1-1", 
                "length": 509, 
                "sequence": "MSVSALSPTRFADSLSGFLQVASVLGLLLLLVKAVQFYLHRKWLLKALQQFPSPPFHWFFGHEQFKGEQELKEVVSCIEHFPSAFPCWFWGSNAYLTVYDPDYMKVILGRSDPKANGIYRLLAPWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLAGQDSSIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYKTYLQAIGDLNNLFHSRVRNIFHQNDTIYRLSSNGRLAKQACQLAHDHTDGVIKMRKDQLQDEGELENIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLHFELLPDPTRVPEPLARIVLKSKNGIYLHLKKLH"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:100040843", 
            "resource": "KEGG Pathway", 
            "id": "mmu:100040843", 
            "name": ""
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211935", 
            "resource": "Reactome", 
            "id": "R-MMU-211935", 
            "name": "Fatty acids"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211958", 
            "resource": "Reactome", 
            "id": "R-MMU-211958", 
            "name": "Miscellaneous substrates"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211979", 
            "resource": "Reactome", 
            "id": "R-MMU-211979", 
            "name": "Eicosanoids"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2142691", 
            "resource": "Reactome", 
            "id": "R-MMU-2142691", 
            "name": "Synthesis of Leukotrienes (LT) and Eoxins (EX)"
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "F8WGU9-1", 
            "protein_name": "Cytochrome P450, family 4, subfamily a, polypeptide 31", 
            "sequence": {
                "length": 509, 
                "sequence": "MSVSALSLTRFAGSLSGFLQVASVFCLLLLLVKAVQVYLHRKWLLKALQQFPSPPFHWFFGHEQFKGDQELQEIVSCIENFPSAFPRWFWGSKAYLTVYDPDYMKVILGRSDPKANGAYRLLAPWIGYGLLLLNGQSWFQHRKMLTPAFHYDILKTYVKNMADSIRLMLDKWERLAGQDSSIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYKTYLQAIGDLNNLVHSRVRNMFHQNDTIYKLSSNGRLSNQACQLAHDHTDGVIKMRKDQLQDEGELENIKKKRRLDFLDILLFARMENEDSMSDKDLRAEVDTFMIEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPSIGRELSTSVTFPDGCSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRVPMSLARFVLKSKNGIYLHLKKVH"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/128044", 
                    "id": "128044", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "O88833-1", 
            "protein_name": "Cytochrome P450 4A10", 
            "sequence": {
                "length": 509, 
                "sequence": "MSVSALSPTRFADSLSGFLQVASVLGLLLLLVKAVQFYLHRQWLLKAFQQFPSPPFHWFFGHEKFKGDQELQEIVSCIENFPSAFPRWFWGSKAYLTVYDPDYMKVILGRSDPKANGAYRLLAPWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLADQDSSIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYRTYLQAIGDLNNLFHSRVRNIFHQNDTIYKLSSNGRLAKQACQLAHDHTDGVIKLRKDQLQDEGELEKIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPDHQQRCREEVQSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLRFELLPDPTRVPMPLARLVLKSKNGIYLHLKKLH"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/128044", 
                    "id": "128044", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "P08516-1", 
            "protein_name": "Cytochrome P450 4A10", 
            "sequence": {
                "length": 509, 
                "sequence": "MSVSALSSTRFTGSISGFLQVASVLGLLLLLVKAVQFYLQRQWLLKAFQQFPSPPFHWFFGHKQFQGDKELQQIMTCVENFPSAFPRWFWGSKAYLIVYDPDYMKVILGRSDPKANGVYRLLAPWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWEQLAGQDSSIEIFQHISLMTLDTVMKCAFSHNGSVQVDGNYKSYIQAIGNLNDLFHSRVRNIFHQNDTIYNFSSNGHLFNRACQLAHDHTDGVIKLRKDQLQNAGELEKVKKKRRLDFLDILLLARMENGDSLSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSVLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGIQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPRHSHSFLPFSGGARNCIGKQFAMSEMKVIVALTLLRFELLPDPTKVPIPLPRLVLKSKNGIYLYLKKLH"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/128044", 
                    "id": "128044", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Rat", 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }, 
        {
            "uniprot_canonical_ac": "Q02928-1", 
            "protein_name": "Cytochrome P450 4A11", 
            "sequence": {
                "length": 519, 
                "sequence": "MSVSVLSPSRLLGDVSGILQAASLLILLLLLIKAVQLYLHRQWLLKALQQFPCPPSHWLFGHIQELQQDQELQRIQKWVETFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCAFSHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRRLPNPCEDKDQL"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/128044", 
                    "id": "128044", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093651.1", 
        "ac": "NP_001093651.1", 
        "name": "cytochrome P450, family 4, subfamily a, polypeptide 32", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "iron ion binding", 
                        "id": "GO:0005506"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "heme binding", 
                        "id": "GO:0020037"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008392", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "arachidonic acid epoxygenase activity", 
                        "id": "GO:0008392"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050051", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "leukotriene-B4 20-monooxygenase activity", 
                        "id": "GO:0050051"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018685", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "alkane 1-monooxygenase activity", 
                        "id": "GO:0018685"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008391", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "arachidonic acid monooxygenase activity", 
                        "id": "GO:0008391"
                    }
                ], 
                "total": 6, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "intracellular membrane-bounded organelle", 
                        "id": "GO:0043231"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "apical plasma membrane", 
                        "id": "GO:0016324"
                    }
                ], 
                "total": 3, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046456", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "icosanoid biosynthetic process", 
                        "id": "GO:0046456"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "kidney development", 
                        "id": "GO:0001822"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043651", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "linoleic acid metabolic process", 
                        "id": "GO:0043651"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019369", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "arachidonic acid metabolic process", 
                        "id": "GO:0019369"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048252", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8T1", 
                                "id": "A2A8T1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "lauric acid metabolic process", 
                        "id": "GO:0048252"
                    }
                ], 
                "total": 5, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2A8T1", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Cyp4a32"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A8T1", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Cyp4a32"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000063929", 
            "id": "ENSMUSG00000063929", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/100040843", 
            "id": "100040843", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", 
            "id": "IPR001128", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", 
            "id": "IPR002401", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", 
            "id": "IPR017972", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", 
            "id": "IPR036396", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:100040843", 
            "id": "mmu:100040843", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:3717148", 
            "id": "3717148", 
            "database": "MGI"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/GEWVIPE/", 
            "id": "GEWVIPE", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=1247045at2759", 
            "id": "1247045at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00067", 
            "id": "PF00067", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211935", 
            "id": "R-MMU-211935", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211958", 
            "id": "R-MMU-211958", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211979", 
            "id": "R-MMU-211979", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2142691", 
            "id": "R-MMU-2142691", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093651.1", 
            "id": "NP_001093651.1", 
            "database": "RefSeq"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 58233.0, 
        "chemical_mass": 58233.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A8T1", 
            "name": "Cyp4a32", 
            "locus": {
                "end_pos": 115621602, 
                "strand": "+", 
                "start_pos": 115600969, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000063929", 
                        "id": "ENSMUSG00000063929", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A8T1", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Cytochrome P450, family 4, subfamily a, polypeptide 32"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2A8T1", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "cytochrome P450, family 4, subfamily a, polypeptide 32"
        }
    ]
}