{
    "uniprot_canonical_ac": "A6NCK2-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A6NCK2-1|TR43B_HUMAN Isoform 1 of Tripartite motif-containing protein 43B  OS=Homo sapiens OX=9606 GN=TRIM43B PE=3 SV=3 CANONICAL=A6NCK2-1", 
        "length": 446, 
        "sequence": "MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNILLKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHYPIEEAAEEDREKLLKQMRILWKKIQENQRNLYEERRTAFLLRGDVVLRAQMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPEVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITGLVYRLNRFRVEISFHFEVTNHNIRLFEDVRSWMFRRGPLNSDRSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSWIRKNSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYTGHR"
    }, 
    "uniprot_id": "TR43B_HUMAN", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Human", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A6NCK2", 
                    "id": "A6NCK2", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "publication": [], 
    "uniprot_ac": "A6NCK2", 
    "site_annotation": [
        {
            "end_pos": 357, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 355
        }, 
        {
            "end_pos": 364, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 362
        }, 
        {
            "end_pos": 420, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 418
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A6NCK2#A6NCK2-1", 
            "isoform_ac": "A6NCK2-1", 
            "locus": {
                "end_pos": 95477167, 
                "strand": "+", 
                "start_pos": 95482714, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000639673", 
                        "id": "ENST00000639673", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000492719", 
                        "id": "ENSP00000492719", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A6NCK2-1|TR43B_HUMAN Isoform 1 of Tripartite motif-containing protein 43B  OS=Homo sapiens OX=9606 GN=TRIM43B PE=3 SV=3 CANONICAL=A6NCK2-1", 
                "length": 446, 
                "sequence": "MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNILLKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHYPIEEAAEEDREKLLKQMRILWKKIQENQRNLYEERRTAFLLRGDVVLRAQMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPEVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITGLVYRLNRFRVEISFHFEVTNHNIRLFEDVRSWMFRRGPLNSDRSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSWIRKNSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYTGHR"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:653192", 
            "resource": "KEGG Pathway", 
            "id": "hsa:653192", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "D3ZLN6-1", 
            "protein_name": "Tripartite motif-containing 43A", 
            "sequence": {
                "length": 451, 
                "sequence": "MESDNLQASQEILTCFICLGIFTDLVLTRCGHPFCRACLLLFSADTQIPIHCPLCRHPSKPNFRTAIPGKKLISIVRKERIKKYLSSEEHKCMTHKERKTIFCDENRVLLCQLCSKSQEHRGHRHCHIEEAVLKQMEKLLKQMESLLKKIQELQENLEAEKTMTDQWMDYVTLREEMIRTEYRKLYPSLDEEEAQHIECMKNQGNTNLEELRKSEAMMVHKRSQLMKVYQELMTMSQKPYEVLQQGLDDLFRRCELVQLGMPQVMKPELSAHPNAGLTARFSFFKVKIFFQNLIILNCKMSQFFDIRRFTSRPCHQNTSLDSAGSYRASWGAMDFTTGKHYWELDLKDCEHWAVGVCSNVWLSRSHKKIGSSGAFLLVCVKEGNHYSLFTTCPVSHHYIEKPTGRVGVFLDCEGGCMSFLDVAKSSLIHSYHPEAFSLRVRPFFSTVYTRS"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/85096", 
                    "id": "85096", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Rat", 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }, 
        {
            "uniprot_canonical_ac": "Q96BQ3-1", 
            "protein_name": "Tripartite motif-containing protein 43", 
            "sequence": {
                "length": 446, 
                "sequence": "MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNILLKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHHPIEEAAEEHREKLLKQMRILWKKIQENQRNLYEEGRTAFLWRGNVVLRAQMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPDVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITGLVYRLNRFRVEISFHFEVTNHNIRLFEDVRSWMFRRGPLNSDRSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSWIRKNSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYTGHR"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/85096", 
                    "id": "85096", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157936.1", 
        "ac": "NP_001157936.1", 
        "name": "tripartite motif-containing protein 43B", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A6NCK2", 
                                "id": "A6NCK2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "zinc ion binding", 
                        "id": "GO:0008270"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A6NCK2", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "TRIM43B"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6NCK2", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "TRIM43B"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A6NCK2", 
            "id": "A6NCK2", 
            "database": "BioMuta"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=TRIM43B", 
            "id": "TRIM43B", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/653192", 
            "id": "653192", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=37146", 
            "id": "37146", 
            "database": "HGNC"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", 
            "id": "IPR000315", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", 
            "id": "IPR001841", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", 
            "id": "IPR001870", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", 
            "id": "IPR003877", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", 
            "id": "IPR003879", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", 
            "id": "IPR013083", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", 
            "id": "IPR013320", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", 
            "id": "IPR017907", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:653192", 
            "id": "hsa:653192", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A6NCK2", 
            "id": "NX_A6NCK2", 
            "database": "neXtProt"
        }, 
        {
            "url": "http://www.orthodb.org/?query=565446at2759", 
            "id": "565446at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00622", 
            "id": "PF00622", 
            "database": "Pfam"
        }, 
        {
            "url": "https://pharos.nih.gov/targets/A6NCK2", 
            "id": "A6NCK2", 
            "database": "PHAROS"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A6NCK2", 
            "id": "PR_A6NCK2", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001157936.1", 
            "id": "NP_001157936.1", 
            "database": "RefSeq"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 52310.0, 
        "chemical_mass": 52310.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A6NCK2", 
            "name": "TRIM43B", 
            "locus": {
                "end_pos": 95476967, 
                "strand": "-", 
                "start_pos": 95484731, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000144010", 
                        "id": "ENSG00000144010", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A6NCK2", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Tripartite motif-containing protein 43B"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A6NCK2", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "tripartite motif-containing protein 43-like protein 1"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A6NCK2", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "tripartite motif-containing protein 43B"
        }
    ]
}