{
    "uniprot_canonical_ac": "A2BFL2-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A2BFL2-1|ZY11A_MOUSE Isoform 1 of Protein zyg-11 homolog A  OS=Mus musculus OX=10090 GN=Zyg11a PE=2 SV=1 CANONICAL=A2BFL2-1", 
        "length": 627, 
        "sequence": "MAWQGKLTDRTASIFQGKQMSLKLINIPRVKLSAAAFTKAFCHHKLIEVNATSVDSELLAPDIIHALQSSAWIQKNLQCLVLDSVSIPPNSGLVALSHFTGLHTLSVANVSFCNEDLVSVSQLPNLGSLDISNTLVTNISALLSCKNRLRSLTMHYLKCLAMNSPQVLAVIRQLKCLLHLDISDHQQLRSDLAFYLLQQKDILPNLTSLDISGGTDVTDQAVESFLQHRPAMRFVGLLYTDAGYSDFFTAKQGLKVAGGANMSQISEALSRYRNRSCFVKEALFRLFTETLSLRAVLPVMLKLVAIGMRNHPLDLPVQFTASACALNLTRQELARGMPVRLLAEITDLLFKATKNFPYYQQLQKNCLLSLTSSRILMDVPFDRFDAAKLALRWVCRRESPKLRTMAVSITSILALKLSPEEMGQLQEELIMAIKELLTIIRQKLAENLDDVTFLFTLKALWNLTDECPLACKYFMENEGLATVIRVLETFSISVIQSKVLGLLNNVAEVRELSSKLVTEDVIERIISLLHSSNLEVSFLAAGVLAHLTCDRQHWLSRDLQRTDLLRYLHLAIQNWPSSRCDMSVLVTYRSFKAFSPLLVNFSQPEVQRWALWAIHHVCSKNPRPKDV"
    }, 
    "uniprot_id": "ZY11A_MOUSE", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "taxid": 10090, 
            "name": "Mus musculus", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2BFL2", 
                    "id": "A2BFL2", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "crossref_internal": {
        "gene": [
            "Zyg11a"
        ], 
        "site": [
            "A2BFL2-1.327.329", 
            "A2BFL2-1.600.602", 
            "A2BFL2-1.261.263", 
            "A2BFL2-1.462.464", 
            "A2BFL2-1.109.111", 
            "A2BFL2-1.205.207", 
            "A2BFL2-1.50.52", 
            "A2BFL2-1.138.140", 
            "A2BFL2-1.274.276"
        ], 
        "species": [
            10090
        ]
    }, 
    "publication": [], 
    "uniprot_ac": "A2BFL2", 
    "site_annotation": [
        {
            "end_pos": 111, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 109
        }, 
        {
            "end_pos": 140, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 138
        }, 
        {
            "end_pos": 207, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 205
        }, 
        {
            "end_pos": 263, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 261
        }, 
        {
            "end_pos": 276, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 274
        }, 
        {
            "end_pos": 329, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 327
        }, 
        {
            "end_pos": 464, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 462
        }, 
        {
            "end_pos": 52, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 50
        }, 
        {
            "end_pos": 602, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 600
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2BFL2#A0A1Y7VNL1-1", 
            "isoform_ac": "A0A1Y7VNL1-1", 
            "sequence": {
                "header": "tr|A0A1Y7VNL1-1|ZY11A_MOUSE Computationally mapped isoform of Protein zyg-11 homolog A  OS=Mus musculus OX=10090 GN=Zyg11a PE=2 SV=1 CANONICAL=A2BFL2-1", 
                "length": 760, 
                "sequence": "MVHFLHPLLWPRALVLPDAQQDAQGHCLVQEEASPYSLVNICLDVLIAELDKWCSKRPDGTLCLPEHWYFPHEIADKFLERMAWQGKLTDRTASIFQGKQMSLKLINIPRVKLSAAAFTKAFCHHKLIEVNATSVDSELLAPDIIHALQSSAWIQKNLQCLVLDSVSIPPNSGLVALSHFTGLHTLSVANVSFCNEDLVSVSQLPNLGSLDISNTLVTNISALLSCKNRLRSLTMHYLKCLAMNSPQVLAVIRQLKCLLHLDISDHQQLRSDLAFYLLQQKDILPNLTSLDISGGTDVTDQAVESFLQHRPAMRFVGLLYTDAGYSDFFTAKQGLKVAGGANMSQISEALSRYRNRSCFVKEALFRLFTETLSLRAVLPVMLKLVAIGMRNHPLDLPVQFTASACALNLTRQELARGMPVRLLAEITDLLFKATKNFPYYQQLQKNCLLSLTSSRILMDVPFDRFDAAKLALRWVCRRESPKLRTMAVSITSILALKLSPEEMGQLQEELIMAIKELLTIIRQKLAENLDDVTFLFTLKALWNLTDECPLACKYFMENEGLATVIRVLETFSISVIQSKVLGLLNNVAEVRELSSKLVTEDVIERIISLLHSSNLEVSFLAAGVLAHLTCDRQHWLSRDLQRTDLLRYLHLAIQNWPSSRCDMSVLVTYRSFKAFSPLLVNFSQPEVQRWALWAIHHVCSKNPSKYCQLLVEGGGLQLMYDIQEHGQASAQVRQMVSSILEEFRMHFTSDRRPPQPQGPL"
            }, 
            "locus": {
                "chromosome": "4", 
                "end_pos": 108181741, 
                "start_pos": 108217922, 
                "strand": "+", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000223127", 
                        "id": "ENSMUST00000223127", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000152477", 
                        "id": "ENSMUSP00000152477", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2BFL2#A0A217FL76-1", 
            "isoform_ac": "A0A217FL76-1", 
            "sequence": {
                "header": "tr|A0A217FL76-1|ZY11A_MOUSE Computationally mapped isoform of Protein zyg-11 homolog A  OS=Mus musculus OX=10090 GN=Zyg11a PE=2 SV=1 CANONICAL=A2BFL2-1", 
                "length": 708, 
                "sequence": "MVHFLHPLLWPRALVLPDAQQDAQGHCLVQEEASPYSLVNICLDVLIAELDKWCSKRPDGTLCLPEHWYFPHEIADKFLERMAWQGKLTDRTASIFQGKQMSLKLINIPRVKLSAAAFTKAFCHHKLIEVNATSVDSELLAPDIIHALQSSAWIQKNLQCLVLDSVSIPPNSGLVALSHFTGLHTLSVANVSFCNEDLVSVSQLPNLGSLDISNTLVTNISALLSCKNRLRSLTMHYLKCLAMNSPQVLAVIRQLKCLLHLDISDHQQLRSDLAFYLLQQKDILPNLTSLDISGGTDVTDQAVESFLQHRPAMRFVGLLYTDAGYSDFFTAKQGLKVAGGANMSQISEALSRYRNRSCFVKEALFRLFTETLSLRAVLPVMLKLVAIGMRNHPLDLPVQFTASACALNLTRQELARGMPVRLLAEITDLLFKATKNFPYYQQLQKNCLLSLTSSRILMDVPFDRFDAAKLALRWVCRRESPKLRTMAVSITSILALKLSPEEMGQLQEELIMAIKELLTIIRQKLAENLDDVTFLFTLKALWNLTDECPLACKYFMENEGLATVIRVLETFSISVIQSKVLGLLNNVAEVRELSSKLVTEDVIERIISLLHSSNLEVSFLAAGVLAHLTCDRQHWLSRDLQRTDLLRYLHLAIQNWPSSRCDMSVLVTYRSFKAFSPLLVNFSQPEVQRWALWAIHHVCSKNPRPKDV"
            }, 
            "locus": {
                "chromosome": "4", 
                "end_pos": 108182105, 
                "start_pos": 108217922, 
                "strand": "+", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000106690", 
                        "id": "ENSMUST00000106690", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000102301", 
                        "id": "ENSMUSP00000102301", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2BFL2#A2BFL2-1", 
            "isoform_ac": "A2BFL2-1", 
            "sequence": {
                "header": "sp|A2BFL2-1|ZY11A_MOUSE Isoform 1 of Protein zyg-11 homolog A  OS=Mus musculus OX=10090 GN=Zyg11a PE=2 SV=1 CANONICAL=A2BFL2-1", 
                "length": 627, 
                "sequence": "MAWQGKLTDRTASIFQGKQMSLKLINIPRVKLSAAAFTKAFCHHKLIEVNATSVDSELLAPDIIHALQSSAWIQKNLQCLVLDSVSIPPNSGLVALSHFTGLHTLSVANVSFCNEDLVSVSQLPNLGSLDISNTLVTNISALLSCKNRLRSLTMHYLKCLAMNSPQVLAVIRQLKCLLHLDISDHQQLRSDLAFYLLQQKDILPNLTSLDISGGTDVTDQAVESFLQHRPAMRFVGLLYTDAGYSDFFTAKQGLKVAGGANMSQISEALSRYRNRSCFVKEALFRLFTETLSLRAVLPVMLKLVAIGMRNHPLDLPVQFTASACALNLTRQELARGMPVRLLAEITDLLFKATKNFPYYQQLQKNCLLSLTSSRILMDVPFDRFDAAKLALRWVCRRESPKLRTMAVSITSILALKLSPEEMGQLQEELIMAIKELLTIIRQKLAENLDDVTFLFTLKALWNLTDECPLACKYFMENEGLATVIRVLETFSISVIQSKVLGLLNNVAEVRELSSKLVTEDVIERIISLLHSSNLEVSFLAAGVLAHLTCDRQHWLSRDLQRTDLLRYLHLAIQNWPSSRCDMSVLVTYRSFKAFSPLLVNFSQPEVQRWALWAIHHVCSKNPRPKDV"
            }, 
            "locus": {}
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2BFL2#F8WHU3-1", 
            "isoform_ac": "F8WHU3-1", 
            "sequence": {
                "header": "tr|F8WHU3-1|ZY11A_MOUSE Computationally mapped isoform of Protein zyg-11 homolog A  OS=Mus musculus OX=10090 GN=Zyg11a PE=2 SV=1 CANONICAL=A2BFL2-1", 
                "length": 706, 
                "sequence": "MVHFLHPLLWPRALVLPDAQQDAQGHCLEEASPYSLVNICLDVLIAELDKWCSKRPDGTLCLPEHWYFPHEIADKFLERMAWQGKLTDRTASIFQGKQMSLKLINIPRVKLSAAAFTKAFCHHKLIEVNATSVDSELLAPDIIHALQSSAWIQKNLQCLVLDSVSIPPNSGLVALSHFTGLHTLSVANVSFCNEDLVSVSQLPNLGSLDISNTLVTNISALLSCKNRLRSLTMHYLKCLAMNSPQVLAVIRQLKCLLHLDISDHQQLRSDLAFYLLQQKDILPNLTSLDISGGTDVTDQAVESFLQHRPAMRFVGLLYTDAGYSDFFTAKQGLKVAGGANMSQISEALSRYRNRSCFVKEALFRLFTETLSLRAVLPVMLKLVAIGMRNHPLDLPVQFTASACALNLTRQELARGMPVRLLAEITDLLFKATKNFPYYQQLQKNCLLSLTSSRILMDVPFDRFDAAKLALRWVCRRESPKLRTMAVSITSILALKLSPEEMGQLQEELIMAIKELLTIIRQKLAENLDDVTFLFTLKALWNLTDECPLACKYFMENEGLATVIRVLETFSISVIQSKVLGLLNNVAEVRELSSKLVTEDVIERIISLLHSSNLEVSFLAAGVLAHLTCDRQHWLSRDLQRTDLLRYLHLAIQNWPSSRCDMSVLVTYRSFKAFSPLLVNFSQPEVQRWALWAIHHVCSKNPRPKDV"
            }, 
            "locus": {
                "chromosome": "4", 
                "end_pos": 108182105, 
                "start_pos": 108217922, 
                "strand": "+", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000043793", 
                        "id": "ENSMUST00000043793", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000038478", 
                        "id": "ENSMUSP00000038478", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }
        }
    ], 
    "pathway": [], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A2BFL2#function", 
            "annotation": "Probably acts as target recruitment subunit in an E3 ubiquitin ligase complex ZYGA-CUL2-elongin BC.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2BFL2#function", 
                    "id": "A2BFL2", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }
    ], 
    "refseq": {}, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031462", 
                        "pmid": "21873635", 
                        "id": "GO:0031462", 
                        "name": "Cul2-RING ubiquitin ligase complex", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2BFL2", 
                                "id": "A2BFL2", 
                                "database": "UniProtKB"
                            }
                        ]
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2BFL2", 
            "resource": "UniProtKB", 
            "type": "recommended", 
            "name": "Zyg11a"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000034645", 
            "id": "ENSMUSG00000034645", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", 
            "id": "IPR000225", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", 
            "id": "IPR011989", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", 
            "id": "IPR016024", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", 
            "id": "IPR032675", 
            "database": "InterPro"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:2446208", 
            "id": "2446208", 
            "database": "MGI"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2BFL2", 
            "id": "PR_A2BFL2", 
            "database": "PRO"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 70404.0, 
        "chemical_mass": 70404.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2BFL2", 
            "name": "Zyg11a", 
            "locus": {
                "chromosome": "4", 
                "end_pos": 108181738, 
                "start_pos": 108218048, 
                "strand": "-", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000034645", 
                        "id": "ENSMUSG00000034645", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2BFL2", 
            "resource": "UniProtKB", 
            "type": "recommended", 
            "name": "Protein zyg-11 homolog A"
        }
    ]
}