{
    "uniprot_canonical_ac": "A2AM05-1", 
    "ptm_annotation": [
        {
            "annotation": "Phosphorylated directly or indirectly by NEK2.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AM05", 
                    "id": "A2AM05", 
                    "database": "UniProtKB"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/Q9NXG0", 
                    "id": "Q9NXG0", 
                    "database": "PubMed"
                }
            ]
        }
    ], 
    "sequence": {
        "header": "sp|A2AM05-1|CNTLN_MOUSE Isoform 1 of Centlein  OS=Mus musculus OX=10090 GN=Cntln PE=1 SV=1 CANONICAL=A2AM05-1", 
        "length": 1397, 
        "sequence": "MAARSPSSSPPPPPVRRSSRRSLRVGRGAEVHAVRSEASGLAGAAREVVADKSDLLWRGEEGSGGRRGSGRAGAAVAPVASAPAGSWWPEGLSSEEAKATRSQLLEEELSSLKEELALCQADKEFVWSLWRRLQATNPDLTQTVSLVVEREKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVHTAESMSYQKLYNELHMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEIEYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVKRSRSLSPKSSFMGSEELRKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPHQLRQEDSDAVWNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAKALRGKDEEVVCPEERAHRPTDKAKSEMATTDVRARRCDCKTATTKVKFKAAKRKCSVGRHHTVLNHSIKVMSHVENLSKDGWEDVSEGSSDSETQTFQNLGTIIVETSQNISPIEDGRNQKEIDQTEGSCAQQRAMQTYSCEDIKAPQSISHNKNTKKMTFQKKSGSLQKSLHSALPARVNREKCKNLPAQKSSSSTISLRERIVSLQQQNSLLQNARRAAEASAKEYKEANEKLLHQQQVSDHRFQTSRQTIKKLTLDLAELRKEKEDLLKKVESSSDIMSLAEEVSRIMAPQIKVTTLGPSRSMDLEMKQLQCKLKNATNELTKQSSNVKSLRMELLAKDDHIKEMHERTSRMERDITMKRHLIEDLKFRQKVNSESNESFNEMLETLEKKVKSLTEECSNKKVSVDSLKQRLNVAVKEKSQYEQMYQKTKEELEKKDLKMSVLISKLNDTETAMAQIETAASEQLQGLALQSEQVLEGAQKKLLSANEKIEEFTVFVKALVNELQSDVHGTRHQIRELKKMQKSRHACKTSTHKAQTLAASILNISRSDLEEILDTEDELEIEKTKIDIENDKEWMLYIQKLLEGQLPFASYLLEAVLEKIKENKKLTEGYFTVMKDTK"
    }, 
    "uniprot_id": "CNTLN_MOUSE", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "taxid": 10090, 
            "name": "Mus musculus", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AM05", 
                    "id": "A2AM05", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "crossref_internal": {
        "gene": [
            "Cntln"
        ], 
        "site": [
            "A2AM05-1.1094.1096", 
            "A2AM05-1.1334.1334", 
            "A2AM05-1.885.887", 
            "A2AM05-1.5.5", 
            "A2AM05-1.1155.1157", 
            "A2AM05-1.1226.1228", 
            "A2AM05-1.22.22", 
            "A2AM05-1.1322.1324", 
            "A2AM05-1.482.484", 
            "A2AM05-1.9.9", 
            "A2AM05-1.840.842", 
            "A2AM05-1.1219.1219", 
            "A2AM05-1.851.853"
        ], 
        "species": [
            10090
        ]
    }, 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/18086554", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "18086554"
                }
            ], 
            "title": "Identification and characterization of the novel centrosomal protein centlein.", 
            "journal": "Biochemical and biophysical research communications", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_780484.2", 
                    "id": "NP_780484.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Makino K, Umeda K, Uezu A, Hiragami Y, Sakamoto T, Ihn H, Nakanishi H", 
            "date": "2008"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/26915804", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "26915804"
                }
            ], 
            "title": "Centlein, a novel microtubule-associated protein stabilizing microtubules and involved in neurite formation.", 
            "journal": "Biochemical and biophysical research communications", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_780484.2", 
                    "id": "NP_780484.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Jing Z, Yin H, Wang P, Gao J, Yuan L", 
            "date": "2016"
        }
    ], 
    "uniprot_ac": "A2AM05", 
    "site_annotation": [
        {
            "end_pos": 1096, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1094
        }, 
        {
            "end_pos": 1157, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1155
        }, 
        {
            "end_pos": 1228, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1226
        }, 
        {
            "end_pos": 1324, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1322
        }, 
        {
            "end_pos": 484, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 482
        }, 
        {
            "end_pos": 842, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 840
        }, 
        {
            "end_pos": 853, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 851
        }, 
        {
            "end_pos": 887, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 885
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AM05#A2AM05-1", 
            "isoform_ac": "A2AM05-1", 
            "sequence": {
                "header": "sp|A2AM05-1|CNTLN_MOUSE Isoform 1 of Centlein  OS=Mus musculus OX=10090 GN=Cntln PE=1 SV=1 CANONICAL=A2AM05-1", 
                "length": 1397, 
                "sequence": "MAARSPSSSPPPPPVRRSSRRSLRVGRGAEVHAVRSEASGLAGAAREVVADKSDLLWRGEEGSGGRRGSGRAGAAVAPVASAPAGSWWPEGLSSEEAKATRSQLLEEELSSLKEELALCQADKEFVWSLWRRLQATNPDLTQTVSLVVEREKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVHTAESMSYQKLYNELHMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEIEYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVKRSRSLSPKSSFMGSEELRKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPHQLRQEDSDAVWNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAKALRGKDEEVVCPEERAHRPTDKAKSEMATTDVRARRCDCKTATTKVKFKAAKRKCSVGRHHTVLNHSIKVMSHVENLSKDGWEDVSEGSSDSETQTFQNLGTIIVETSQNISPIEDGRNQKEIDQTEGSCAQQRAMQTYSCEDIKAPQSISHNKNTKKMTFQKKSGSLQKSLHSALPARVNREKCKNLPAQKSSSSTISLRERIVSLQQQNSLLQNARRAAEASAKEYKEANEKLLHQQQVSDHRFQTSRQTIKKLTLDLAELRKEKEDLLKKVESSSDIMSLAEEVSRIMAPQIKVTTLGPSRSMDLEMKQLQCKLKNATNELTKQSSNVKSLRMELLAKDDHIKEMHERTSRMERDITMKRHLIEDLKFRQKVNSESNESFNEMLETLEKKVKSLTEECSNKKVSVDSLKQRLNVAVKEKSQYEQMYQKTKEELEKKDLKMSVLISKLNDTETAMAQIETAASEQLQGLALQSEQVLEGAQKKLLSANEKIEEFTVFVKALVNELQSDVHGTRHQIRELKKMQKSRHACKTSTHKAQTLAASILNISRSDLEEILDTEDELEIEKTKIDIENDKEWMLYIQKLLEGQLPFASYLLEAVLEKIKENKKLTEGYFTVMKDTK"
            }, 
            "locus": {
                "chromosome": "4", 
                "end_pos": 84884465, 
                "start_pos": 85130740, 
                "strand": "-", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000047023", 
                        "id": "ENSMUST00000047023", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000044138", 
                        "id": "ENSMUSP00000044138", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AM05#A2AM05-2", 
            "isoform_ac": "A2AM05-2", 
            "sequence": {
                "header": "sp|A2AM05-2|CNTLN_MOUSE Isoform 2 of Centlein  OS=Mus musculus OX=10090 GN=Cntln PE=1 SV=1 CANONICAL=A2AM05-1", 
                "length": 318, 
                "sequence": "MAARSPSSSPPPPPVRRSSRRSLRVGRGAEVHAVRSEASGLAGAAREVVADKSDLLWRGEEGSGGRRGSGRAGAAVAPVASAPAGSWWPEGLSSEEAKATRSQLLEEELSSLKEELALCQADKEFVWSLWRRLQATNPDLTQTVSLVVEREKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVQGGPVSMSCPGPSFLQQPNIRFSLNNKLSIQIHQ"
            }, 
            "locus": {
                "chromosome": "4", 
                "end_pos": 84884465, 
                "start_pos": 84957284, 
                "strand": "-", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000102819", 
                        "id": "ENSMUST00000102819", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000099883", 
                        "id": "ENSMUSP00000099883", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AM05#A2AM05-3", 
            "isoform_ac": "A2AM05-3", 
            "sequence": {
                "header": "sp|A2AM05-3|CNTLN_MOUSE Isoform 3 of Centlein  OS=Mus musculus OX=10090 GN=Cntln PE=1 SV=1 CANONICAL=A2AM05-1", 
                "length": 262, 
                "sequence": "MKRHLIEDLKFRQKVNSESNESFNEMLETLEKKVKSLTEECSNKKVSVDSLKQRLNVAVKEKSQYEQMYQKTKEELEKKDLKMSVLISKLNDTETAMAQIETAASEQLQGLALQSEQVLEGAQKKLLSANEKIEEFTVFVKALVNELQSDVHGTRHQIRELKKMQKSRHACKTSTHKAQTLAASILNISRSDLEEILDTEDELEIEKTKIDIENDKEWMLYIQKLLEGQLPFASYLLEAVLEKIKENKKLTEGYFTVMKDTK"
            }, 
            "locus": {
                "chromosome": "4", 
                "end_pos": 85098377, 
                "start_pos": 85130740, 
                "strand": "-", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000107190", 
                        "id": "ENSMUST00000107190", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000102808", 
                        "id": "ENSMUSP00000102808", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AM05#A2AM05-4", 
            "isoform_ac": "A2AM05-4", 
            "sequence": {
                "header": "sp|A2AM05-4|CNTLN_MOUSE Isoform 4 of Centlein  OS=Mus musculus OX=10090 GN=Cntln PE=1 SV=1 CANONICAL=A2AM05-1", 
                "length": 1396, 
                "sequence": "MAARSPSSSPPPPPVRRSSRRSLRVGRGAEVHAVRSEASGLAGAAREVVADKSDLLWRGEEGSGGRRGSGRAGAAVAPVASAPAGSWWPEGLSSEEAKATRSQLLEEELSSLKEELALCQADKEFVWSLWRRLQATNPDLTQTVSLVVEREKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVHTAESMSYQKLYNELHMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEIEYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVKRSRSLSPKSSFMGSEELRKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPHQLRQEDSDAVWNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAKALRGKDEEVVCPEERAHRPTDKAKSEMATTDVRARRCDCKTATTKVKFKAAKRKCSVGRHHTVLNHSIKVMSHVENLSKDGWEDVSEGSDSETQTFQNLGTIIVETSQNISPIEDGRNQKEIDQTEGSCAQQRAMQTYSCEDIKAPQSISHNKNTKKMTFQKKSGSLQKSLHSALPARVNREKCKNLPAQKSSSSTISLRERIVSLQQQNSLLQNARRAAEASAKEYKEANEKLLHQQQVSDHRFQTSRQTIKKLTLDLAELRKEKEDLLKKVESSSDIMSLAEEVSRIMAPQIKVTTLGPSRSMDLEMKQLQCKLKNATNELTKQSSNVKSLRMELLAKDDHIKEMHERTSRMERDITMKRHLIEDLKFRQKVNSESNESFNEMLETLEKKVKSLTEECSNKKVSVDSLKQRLNVAVKEKSQYEQMYQKTKEELEKKDLKMSVLISKLNDTETAMAQIETAASEQLQGLALQSEQVLEGAQKKLLSANEKIEEFTVFVKALVNELQSDVHGTRHQIRELKKMQKSRHACKTSTHKAQTLAASILNISRSDLEEILDTEDELEIEKTKIDIENDKEWMLYIQKLLEGQLPFASYLLEAVLEKIKENKKLTEGYFTVMKDTK"
            }, 
            "locus": {
                "chromosome": "4", 
                "end_pos": 84884465, 
                "start_pos": 85130740, 
                "strand": "-", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000169371", 
                        "id": "ENSMUST00000169371", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000130491", 
                        "id": "ENSMUSP00000130491", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:338349", 
            "resource": "KEGG Pathway", 
            "id": "mmu:338349", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AM05#function", 
            "annotation": "Required for centrosome cohesion and recruitment of CEP68 to centrosomes.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AM05#function", 
                    "id": "A2AM05", 
                    "database": "UniProtKB"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_780484.2", 
            "annotation": "Taken together, we propose that centlein is involved in MT stability and neuritogenesis in vivo.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_780484.2", 
                    "id": "NP_780484.2", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "A9ZSY0-1", 
            "protein_name": "Centlein", 
            "sequence": {
                "length": 721, 
                "sequence": "MNLQDELDELKIYMTIDKTTIQELNRCMAEKREEQLFRHHEDAGVKKSTPEKNEKAISEQTLEKVIELENRLKSFEKNSRKLKEESKKLKKENDFLKSHLQHYQEDSESRGKELEKLLRVSSSVEQDKSELQTKVTALEREVTTLRRQVAKAKALRDENEEVVNPEEKEHCPTDKAKSEMATTDVRAQHCDCKTTTTKVKFKAAKKKCSVGRHHTVLNHSIKVMSHVENLSKDGWEDMSEGSSDSETQTFQNLGTVIVETSQNIRPIENDGNQKETDQTEDSRAQQEVQTYSCEDLKAPQNTKKMTFQNKSGSLQKNLHSALPARVNREKCKTKPAQKSSSNTILLRERIVSLQQQNSLLQNARKAAESSAKEFKEANEKLLHQQQISDHRFQTSRQTIKLTLDLAELRKEKEDLLKKVESSSDITSLAEEVSRIMAPQIQVTTLGPSRSTDLEIKQLQCKLKNATNELTKQSSSVKSLKLELLAKDDHMKAMQEKMSRMERDITMKRHLIEDLKFRQKINSESNESFNEMLGTLEKKDLKMNLLISKLNDTETAMAQIKSAASEQLQGLALQSEQVLEGTQKKLLLANEKIEEFTVFVQALVNELQSDAHRTRQQVRELRQTQKSRHACKTSTHKAQTLAASILNISRSDLEEILHTGDEMEIEKTKIDAENDKDWMLYIQKLLQGQLPFASYLLEAVLGKIKENKKLTEGYFTVMKDIK"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/9805", 
                    "id": "9805", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Rat", 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }, 
        {
            "uniprot_canonical_ac": "Q9NXG0-1", 
            "protein_name": "Centlein", 
            "sequence": {
                "length": 1405, 
                "sequence": "MAARSPPSPHPSPPARQLGPRSPRVGRGAEVHAMRSEASGFAGAAREVVADESDKIWVGEEGSGGRRGPGGAAPAHAPLLSAPMGSRRLEGISVEEAMVTRTQLLEEELSSLKEELALCQADKEFVWSLWKRLQVTNPDLTQVVSLVVEREKQKSEAKDRKVLEILQVKDAKIQEFEQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNLYKQNSTHTAQQAELIQQLQVLNMDTQKVLRNQEDVHTAESISYQKLYNELHICFETTKSNEAMLRQSVTNLQDQLLQKEQENAKLKEKLQESQGAPLPLPQESDPDYSAQVPHRPSLSSLETLMVSQKSEIEYLQEKLKIANEKLSENISANKGFSRKSIMTSAEGKHKEPPVKRSRSLSPKSSFTDSEELQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERREEQLFRSGEDDEVKRSTPEKNGKEMLEQTLQKVTELENRLKSFEKRSRKLKEGNKKLMKENDFLKSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALRNENEELINPMEKSHQSADRAKSEMATMKVRSGRYDCKTTMTKVKFKAAKKNCSVGRHHTVLNHSIKVMSNVFENLSKDGWEDVSESSSDSEAQTSQTLGTIIVETSQKISPTEDGKDQKESDPTEDSQTQGKEIVQTYLNIDGKTPKDYFHDKNAKKPTFQKKNCKMQKSSHTAVPTRVNREKYKNITAQKSSSNIILLRERIISLQQQNSVLQNAKKTAELSVKEYKEVNEKLLHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLESSSEITSLAEENSQVTFPRIQVTSLSPSRSMDLEMKQLQYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEKISRMERDITMKRHLIEDLKFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMYQKSKEELEKKDLKLTLLVSRISETESAMAEIETAASKQLQELALQSEQVLEGAQKTLLLANEKVEEFTTFVKALAKELQNDVHVVRRQIRELKKMKKNRDACKTSTHKAQTLAASILNISRSDLEEILDTEDQVEIEKTKIDAENDKEWMLYIQKLLEGQSLTLSPRLKCNGAIVAHQNLRLPDSSSSASAS"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/9805", 
                    "id": "9805", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_780484.2", 
        "ac": "NP_780484.2", 
        "name": "centlein isoform 1", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", 
                        "pmid": "", 
                        "id": "GO:0019901", 
                        "name": "protein kinase binding", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AM05", 
                                "id": "A2AM05", 
                                "database": "UniProtKB"
                            }
                        ]
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019904", 
                        "pmid": "", 
                        "id": "GO:0019904", 
                        "name": "protein domain specific binding", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AM05", 
                                "id": "A2AM05", 
                                "database": "UniProtKB"
                            }
                        ]
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", 
                        "pmid": "", 
                        "id": "GO:0030674", 
                        "name": "protein binding, bridging", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AM05", 
                                "id": "A2AM05", 
                                "database": "UniProtKB"
                            }
                        ]
                    }
                ], 
                "total": 3, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", 
                        "pmid": "", 
                        "id": "GO:0005654", 
                        "name": "nucleoplasm", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AM05", 
                                "id": "A2AM05", 
                                "database": "UniProtKB"
                            }
                        ]
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "", 
                        "id": "GO:0005737", 
                        "name": "cytoplasm", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AM05", 
                                "id": "A2AM05", 
                                "database": "UniProtKB"
                            }
                        ]
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", 
                        "pmid": "", 
                        "id": "GO:0005813", 
                        "name": "centrosome", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AM05", 
                                "id": "A2AM05", 
                                "database": "UniProtKB"
                            }
                        ]
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", 
                        "pmid": "", 
                        "id": "GO:0005829", 
                        "name": "cytosol", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AM05", 
                                "id": "A2AM05", 
                                "database": "UniProtKB"
                            }
                        ]
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", 
                        "pmid": "", 
                        "id": "GO:0005814", 
                        "name": "centriole", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AM05", 
                                "id": "A2AM05", 
                                "database": "UniProtKB"
                            }
                        ]
                    }
                ], 
                "total": 5, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033365", 
                        "pmid": "", 
                        "id": "GO:0033365", 
                        "name": "protein localization to organelle", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AM05", 
                                "id": "A2AM05", 
                                "database": "UniProtKB"
                            }
                        ]
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010457", 
                        "pmid": "", 
                        "id": "GO:0010457", 
                        "name": "centriole-centriole cohesion", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AM05", 
                                "id": "A2AM05", 
                                "database": "UniProtKB"
                            }
                        ]
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2AM05", 
            "resource": "RefSeq", 
            "type": "synonym", 
            "name": "AI448092; B430108F07Rik; D530005L17Rik"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2AM05", 
            "resource": "RefSeq", 
            "type": "synonym", 
            "name": "Cntln"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AM05", 
            "resource": "UniProtKB", 
            "type": "recommended", 
            "name": "Cntln"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000038070", 
            "id": "ENSMUSG00000038070", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/338349", 
            "id": "338349", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038810", 
            "id": "IPR038810", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:338349", 
            "id": "mmu:338349", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:2443104", 
            "id": "2443104", 
            "database": "MGI"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/MSNMFEN/", 
            "id": "MSNMFEN", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=846281at2759", 
            "id": "846281at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18957", 
            "id": "PTHR18957", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2AM05", 
            "id": "PR_A2AM05", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_780484.2", 
            "id": "NP_780484.2", 
            "database": "RefSeq"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [
        {
            "residue": "Ser", 
            "position": "1219", 
            "kinase_gene_name": "Atxn7l3b", 
            "kinase_uniprot_canonical_ac": "Q3UD01-1", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/21183079", 
                    "id": "21183079", 
                    "database": "PubMed"
                }
            ]
        }, 
        {
            "residue": "Ser", 
            "position": "1219", 
            "kinase_gene_name": "", 
            "kinase_uniprot_canonical_ac": "", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AM05", 
                    "id": "A2AM05", 
                    "database": "UniProtKB"
                }
            ]
        }, 
        {
            "residue": "Thr", 
            "position": "1334", 
            "kinase_gene_name": "Atxn7l3b", 
            "kinase_uniprot_canonical_ac": "Q3UD01-1", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/21183079", 
                    "id": "21183079", 
                    "database": "PubMed"
                }
            ]
        }, 
        {
            "residue": "Thr", 
            "position": "1334", 
            "kinase_gene_name": "", 
            "kinase_uniprot_canonical_ac": "", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AM05", 
                    "id": "A2AM05", 
                    "database": "UniProtKB"
                }
            ]
        }, 
        {
            "residue": "Ser", 
            "position": "22", 
            "kinase_gene_name": "", 
            "kinase_uniprot_canonical_ac": "", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AM05", 
                    "id": "A2AM05", 
                    "database": "UniProtKB"
                }
            ]
        }, 
        {
            "residue": "Ser", 
            "position": "5", 
            "kinase_gene_name": "Atxn7l3b", 
            "kinase_uniprot_canonical_ac": "Q3UD01-1", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/19131326", 
                    "id": "19131326", 
                    "database": "PubMed"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/21183079", 
                    "id": "21183079", 
                    "database": "PubMed"
                }
            ]
        }, 
        {
            "residue": "Ser", 
            "position": "5", 
            "kinase_gene_name": "", 
            "kinase_uniprot_canonical_ac": "", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AM05", 
                    "id": "A2AM05", 
                    "database": "UniProtKB"
                }
            ]
        }, 
        {
            "residue": "Ser", 
            "position": "9", 
            "kinase_gene_name": "Atxn7l3b", 
            "kinase_uniprot_canonical_ac": "Q3UD01-1", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/19131326", 
                    "id": "19131326", 
                    "database": "PubMed"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/21183079", 
                    "id": "21183079", 
                    "database": "PubMed"
                }
            ]
        }, 
        {
            "residue": "Ser", 
            "position": "9", 
            "kinase_gene_name": "", 
            "kinase_uniprot_canonical_ac": "", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AM05", 
                    "id": "A2AM05", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "mass": {
        "monoisotopic_mass": 160747.0, 
        "chemical_mass": 160747.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AM05", 
            "name": "Cntln", 
            "locus": {
                "chromosome": "4", 
                "end_pos": 85131921, 
                "start_pos": 84884309, 
                "strand": "+", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000038070", 
                        "id": "ENSMUSG00000038070", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AM05", 
            "resource": "UniProtKB", 
            "type": "recommended", 
            "name": "Centlein"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AM05", 
            "resource": "UniProtKB", 
            "type": "synonym", 
            "name": "Centrosomal protein"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2AM05", 
            "resource": "RefSeq", 
            "type": "synonym", 
            "name": "centlein isoform 1"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2AM05", 
            "resource": "RefSeq", 
            "type": "synonym", 
            "name": "cntln"
        }
    ]
}