{
    "uniprot_canonical_ac": "A0A0G2KB87-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A0A0G2KB87-1|A0A0G2KB87_RAT Isoform 1 of Transmembrane channel-like protein  OS=Rattus norvegicus OX=10116 GN=Tmc1 PE=3 SV=1 CANONICAL=A0A0G2KB87-1", 
        "length": 519, 
        "sequence": "VLLLDFGLAQYSVLFYGYYDNKRTIGWLNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFCSWDYLIGNPETADNKFNSITMNFKEAIIEERAAQVEENIHLIRFLRFLANFFVFLTLGASGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNESLSGNTTGPPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLTIYYLNATAKGQKAANLDLKKKMKQQALENKMRNKKMAAARAAAAAGGQ"
    }, 
    "uniprot_id": "A0A0G2KB87_RAT", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Rat", 
            "taxid": 10116, 
            "name": "Rattus norvegicus", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2KB87", 
                    "id": "A0A0G2KB87", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "crossref_internal": {
        "gene": [
            "Tmc1"
        ], 
        "site": [
            "A0A0G2KB87-1.237.239", 
            "A0A0G2KB87-1.71.73", 
            "A0A0G2KB87-1.250.252", 
            "A0A0G2KB87-1.256.258", 
            "A0A0G2KB87-1.476.478"
        ], 
        "species": [
            10116
        ]
    }, 
    "publication": [], 
    "uniprot_ac": "A0A0G2KB87", 
    "site_annotation": [
        {
            "end_pos": 239, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 237
        }, 
        {
            "end_pos": 252, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 250
        }, 
        {
            "end_pos": 258, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 256
        }, 
        {
            "end_pos": 478, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 476
        }, 
        {
            "end_pos": 73, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 71
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB87#A0A096MKC4-1", 
            "isoform_ac": "A0A096MKC4-1", 
            "sequence": {
                "header": "tr|A0A096MKC4-1|A0A0G2KB87_RAT Computationally mapped isoform of Transmembrane channel-like protein  OS=Rattus norvegicus OX=10116 GN=Tmc1 PE=3 SV=1 CANONICAL=A0A0G2KB87-1", 
                "length": 464, 
                "sequence": "XMTKNIGDDGGGDDNTFNFSWKVFCSWDYLIGNPETADNKFNSITMNFKEAIIEERAAQVEENIHLIRFLRFLANFFVFLTLGASGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNESLSGNTTGPPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMSDHLLSQCYCQGTESSKPGSQKEDETASFGEQNAKQEDGGRSTAAAGGQ"
            }, 
            "locus": {
                "chromosome": "1", 
                "end_pos": 238337358, 
                "start_pos": 238376841, 
                "strand": "+", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000076393", 
                        "id": "ENSRNOT00000076393", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068461", 
                        "id": "ENSRNOP00000068461", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB87#A0A0G2KB87-1", 
            "isoform_ac": "A0A0G2KB87-1", 
            "sequence": {
                "header": "tr|A0A0G2KB87-1|A0A0G2KB87_RAT Isoform 1 of Transmembrane channel-like protein  OS=Rattus norvegicus OX=10116 GN=Tmc1 PE=3 SV=1 CANONICAL=A0A0G2KB87-1", 
                "length": 519, 
                "sequence": "VLLLDFGLAQYSVLFYGYYDNKRTIGWLNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFCSWDYLIGNPETADNKFNSITMNFKEAIIEERAAQVEENIHLIRFLRFLANFFVFLTLGASGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNESLSGNTTGPPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLTIYYLNATAKGQKAANLDLKKKMKQQALENKMRNKKMAAARAAAAAGGQ"
            }, 
            "locus": {
                "chromosome": "1", 
                "end_pos": 238337360, 
                "start_pos": 238381871, 
                "strand": "+", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000077601", 
                        "id": "ENSRNOT00000077601", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000075695", 
                        "id": "ENSRNOP00000075695", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q8R4P5-1", 
            "protein_name": "Transmembrane channel-like protein 1", 
            "sequence": {
                "length": 757, 
                "sequence": "MLQIQVEEKEEDTEESSSEEEEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLRRGAEEEEEIDEEELERLKALLDENRQMIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKKWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFVLTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRTIGWLNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFCSWDYLIGNPETADNKFNSITMNFKEAIIEERAAQVEENIHLIRFLRFLANFFVFLTLGASGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNESLSGLSGNTTGAPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLTIYYLNATAKGQKAANLDLKKKMKQQALENKMRNKKMAAARAAAAAGGQ"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2KB87/", 
                    "id": "A0A0G2KB87", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q8TDI8-1", 
            "protein_name": "Transmembrane channel-like protein 1", 
            "sequence": {
                "length": 760, 
                "sequence": "MSPKKVQIKVEEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPEPEDEETRKAREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGKRWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNMVLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYYDNKRTIGWMNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDDGGGDDNTFNFSWKVFTSWDYLIGNPETADNKFNSITMNFKEAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGSGYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIALKWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLWEANMIKAYNASFSENSTGPPFFVHPADVPRGPCWETMVGQEFVRLTVSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIWMGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLSTMPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILVMVLAIYYLNATAKGQKAANLDLKKKMKMQALENKMRNKKMAAARAAAAAGRQ"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0A0G2KB87/", 
                    "id": "A0A0G2KB87", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }
    ], 
    "refseq": {}, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005216", 
                        "pmid": "21873635", 
                        "id": "GO:0005216", 
                        "name": "ion channel activity", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KB87", 
                                "id": "A0A0G2KB87", 
                                "database": "UniProtKB"
                            }
                        ]
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008381", 
                        "pmid": "21873635", 
                        "id": "GO:0008381", 
                        "name": "mechanosensitive ion channel activity", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KB87", 
                                "id": "A0A0G2KB87", 
                                "database": "UniProtKB"
                            }
                        ]
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", 
                        "pmid": "21873635", 
                        "id": "GO:0005245", 
                        "name": "voltage-gated calcium channel activity", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KB87", 
                                "id": "A0A0G2KB87", 
                                "database": "UniProtKB"
                            }
                        ]
                    }
                ], 
                "total": 3, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005887", 
                        "pmid": "", 
                        "id": "GO:0005887", 
                        "name": "integral component of plasma membrane", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KB87", 
                                "id": "A0A0G2KB87", 
                                "database": "UniProtKB"
                            }
                        ]
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060005", 
                        "pmid": "21873635", 
                        "id": "GO:0060005", 
                        "name": "vestibular reflex", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KB87", 
                                "id": "A0A0G2KB87", 
                                "database": "UniProtKB"
                            }
                        ]
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050910", 
                        "pmid": "21873635", 
                        "id": "GO:0050910", 
                        "name": "detection of mechanical stimulus involved in sensory perception of sound", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KB87", 
                                "id": "A0A0G2KB87", 
                                "database": "UniProtKB"
                            }
                        ]
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB87", 
            "resource": "UniProtKB", 
            "type": "recommended", 
            "name": "Tmc1"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000051262", 
            "id": "ENSRNOG00000051262", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012496", 
            "id": "IPR012496", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038900", 
            "id": "IPR038900", 
            "database": "InterPro"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/SAXEAKE/", 
            "id": "SAXEAKE", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302", 
            "id": "PTHR23302", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF07810", 
            "id": "PF07810", 
            "database": "Pfam"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1308682", 
            "id": "1308682", 
            "database": "RGD"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 59205.0, 
        "chemical_mass": 59205.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB87", 
            "name": "Tmc1", 
            "locus": {
                "chromosome": "1", 
                "end_pos": 238336919, 
                "start_pos": 238441500, 
                "strand": "-", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000051262", 
                        "id": "ENSRNOG00000051262", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2KB87", 
            "resource": "UniProtKB", 
            "type": "recommended", 
            "name": "Transmembrane channel-like protein"
        }
    ]
}