{
    "uniprot_canonical_ac": "A2ACJ2-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A2ACJ2-1|FP100_MOUSE Isoform 1 of Fanconi anemia core complex-associated protein 100  OS=Mus musculus OX=10090 GN=Faap100 PE=2 SV=1 CANONICAL=A2ACJ2-1", 
        "length": 879, 
        "sequence": "MAGASSRVHYLSDFCCPLGGRAAGKPFVLRHEAEVFLSTGREFVYVYDQEGGLLTAVYQFPDQVWHLQLLAIRRALYVLCARTGIYCLSLDSLDRSGSQACEDKEEAAPPYPVIHVDPDACVLPDAALCAFTVLDDMLVTLAQGPTQWKMQLFERPCAGEEPLPRGQIGEVELSTCTPPGGVPEKPAAPRFLPVLCCVFPPDSRAPHGHPQGCGCFTLEEALFGLLFGVDATLLQSPVILCGLPDGQLCCVVLKALVTSGLAPGDPKVLVKILHHLEEPVIFIGALRAEPHEEEAAGELLPGQHEHSDCLVALGHQGRTLAIKASWSESGNLVPELREYCLPGPVLCAACDRDGHVYHSTPSDLCVVDLTRRDSPWNPEKPDGAIGGLPSVLCPASLNICSALALCVTARAPTGSTELLALSSKGRLITCSLDLNSEAPVPAKMAMANAGQKIKELLLDIGDVSERVSFLKKAVDQRNKAITSLNEAMNVSCALLSHPEGDRPIACTITTSWSRLELRDMLMATCTLENSSSFSLDQGWTLCIQVLTSSSALDLDGTGSAFTYTIPVDRLGPGSRREVTLPLGPSESGVLDLPVTMSCWLFYSLREVVGAALAPSDPLEAPYLEQFPLSLPKQEGVCLPLCKRTVDMLQCLRFAGAATHPAQAPCMPGPACEPVETFLKTCQAPGSEPTGAASLRAKYLPPSTASIRVSAGLLRAALEDSHSGFHLCSATLRWLLAENAAVDVVRAQTLSSIQGIAPDGTDVNLTVHEVAVTDLSPAGPIQAVEIQVESSSLANMCRAHHAIIRRIQTMVTEQAALGSSPPDLRMQYLQQIHANHQELLREVQALRDQLCTEDELSSCSTAQKLLHIYKQLRNPSLVLL"
    }, 
    "uniprot_id": "FP100_MOUSE", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2ACJ2", 
                    "id": "A2ACJ2", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "publication": [], 
    "uniprot_ac": "A2ACJ2", 
    "site_annotation": [
        {
            "end_pos": 491, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 489
        }, 
        {
            "end_pos": 531, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 529
        }, 
        {
            "end_pos": 765, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 763
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2ACJ2#A2ACJ2-1", 
            "isoform_ac": "A2ACJ2-1", 
            "locus": {
                "end_pos": 120370291, 
                "strand": "+", 
                "start_pos": 120378706, 
                "chromosome": "11", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000026448", 
                        "id": "ENSMUST00000026448", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000026448", 
                        "id": "ENSMUSP00000026448", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2ACJ2-1|FP100_MOUSE Isoform 1 of Fanconi anemia core complex-associated protein 100  OS=Mus musculus OX=10090 GN=Faap100 PE=2 SV=1 CANONICAL=A2ACJ2-1", 
                "length": 879, 
                "sequence": "MAGASSRVHYLSDFCCPLGGRAAGKPFVLRHEAEVFLSTGREFVYVYDQEGGLLTAVYQFPDQVWHLQLLAIRRALYVLCARTGIYCLSLDSLDRSGSQACEDKEEAAPPYPVIHVDPDACVLPDAALCAFTVLDDMLVTLAQGPTQWKMQLFERPCAGEEPLPRGQIGEVELSTCTPPGGVPEKPAAPRFLPVLCCVFPPDSRAPHGHPQGCGCFTLEEALFGLLFGVDATLLQSPVILCGLPDGQLCCVVLKALVTSGLAPGDPKVLVKILHHLEEPVIFIGALRAEPHEEEAAGELLPGQHEHSDCLVALGHQGRTLAIKASWSESGNLVPELREYCLPGPVLCAACDRDGHVYHSTPSDLCVVDLTRRDSPWNPEKPDGAIGGLPSVLCPASLNICSALALCVTARAPTGSTELLALSSKGRLITCSLDLNSEAPVPAKMAMANAGQKIKELLLDIGDVSERVSFLKKAVDQRNKAITSLNEAMNVSCALLSHPEGDRPIACTITTSWSRLELRDMLMATCTLENSSSFSLDQGWTLCIQVLTSSSALDLDGTGSAFTYTIPVDRLGPGSRREVTLPLGPSESGVLDLPVTMSCWLFYSLREVVGAALAPSDPLEAPYLEQFPLSLPKQEGVCLPLCKRTVDMLQCLRFAGAATHPAQAPCMPGPACEPVETFLKTCQAPGSEPTGAASLRAKYLPPSTASIRVSAGLLRAALEDSHSGFHLCSATLRWLLAENAAVDVVRAQTLSSIQGIAPDGTDVNLTVHEVAVTDLSPAGPIQAVEIQVESSSLANMCRAHHAIIRRIQTMVTEQAALGSSPPDLRMQYLQQIHANHQELLREVQALRDQLCTEDELSSCSTAQKLLHIYKQLRNPSLVLL"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:71885", 
            "resource": "KEGG Pathway", 
            "id": "mmu:71885", 
            "name": ""
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6783310", 
            "resource": "Reactome", 
            "id": "R-MMU-6783310", 
            "name": "Fanconi Anemia Pathway"
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A2ACJ2#function", 
            "annotation": "Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core complex. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed (By similarity).", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2ACJ2#function", 
                    "id": "A2ACJ2", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "D3ZX03-1", 
            "protein_name": "FA core complex-associated protein 100", 
            "sequence": {
                "length": 882, 
                "sequence": "MAGASSRVHYLSDFCCPLGGRAAGKPHVLRHDAEVFLSTGREFVYVYDQEGGLLTAVYQFPDQVWHLQLLATRRALYVLCARTGIYCLSLDSLDRSGSQACEDKEDETHPYPVIHVDPDACVLPDAALCAFTVLDDVLVTLAQGPTQWKMQLFECPHAGEEPRPGGQVGEVQLSTCTPPGGVPGEPTAPCFLPVLCCVFPPDSRAPHGHPQGCGCFMLEEALFGLLFGVDASLLQSPVVLCGLPDGQLCCVALKALVTSELAPGDPKVLVKILHHLEEPVIFIGALRAEPQEEEEEEAVRELLPVENVHSDCLVALGHQGRTLAIRASWSESGNLVPELREYYLPGPVLCAACGRDGHMYHSTPSDLCVVDLTRRDSTWNPEKPDGAIGSLPSTLCPASLNICSALALCVTARAPTGGTELLVLSSKGRLITCSLDLNPEAPVPTKMAVANAGQKIKELLLDIGDVSERVSFLKKAVDQRNKAITSLNEAMNVSCALLSSQEGDRPISCTITTSWSRLELRDMLMATCTLDNSSSFSLDQGWTLCIQVLTSSSALDLDGTGSAFTYTIPVDRLGPGSRREVTLPLGPSESGVLDLPVTMSCWLFYSLREVIGEALAPSDPLEVPYLEKLPLNLPKQEGVCLPLCKRTVDMLQCLRFPGVASHPAQAPSVPGPACDPVETFLKTCQGPGSEPTGAASLRAKYLPPSTASIRVSAGLLRAALEDGHSGFHLCSATLCWLLAENAAVDVLRAQALSSIQGIAPDGTDVNLIVHEVAVTDLSPAGPIQAVEIQVESSSLANMCRAHHAIIRRIKTMVTEQAAQGSSPPDLRMQYLQQIHANHQELLREVQTLRDQLCTEDEVSSCSTAQKLLQIYKQLRNPSLVLL"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/69394", 
                    "id": "69394", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A2ACJ2/", 
                    "id": "A2ACJ2", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Rat", 
            "organism": "Rattus norvegicus", 
            "gene_name": "Faap100", 
            "tax_id": 10116
        }, 
        {
            "uniprot_canonical_ac": "Q0VG06-1", 
            "protein_name": "Fanconi anemia core complex-associated protein 100", 
            "sequence": {
                "length": 881, 
                "sequence": "MAGAAPRVRYLAGFCCPLGGLAAGKPRVLCHEAEVFLSTGSELVYVYDQEGGLLTAAFRFPDQVWHLELLAPRRLLYALCARRGLYCLSLDHPGRSRSTSQDDRDSEDGDQPSPVIPVDPDACILPDAALCAFTLLDSVLVTLVQGPARWKMQLFEQPCPGEDPRPGGQIGEVELSSYTPPAGVPGKPAAPHFLPVLCSVSPSGSRVPHDLLGGSGGFTLEDALFGLLFGADATLLQSPVVLCGLPDGQLCCVILKALVTSRSAPGDPNALVKILHHLEEPVIFIGALKTEPQAAEAAENFLPDEDVHCDCLVAFGHHGRMLAIKASWDESGKLVPELREYCLPGPVLCAACGGGGRVYHSTPSDLCVVDLSRGSTPLGPEQPEEGPGGLPPMLCPASLNICSVVSLSASPRTHEGGTKLLALSAKGRLMTCSLDLDSEMPGPARMTTESAGQKIKELLSGIGNISERVSFLKKAVDQRNKALTSLNEAMNVSCALLSSGTGPRPISCTTSTTWSRLQTQDVLMATCVLENSSSFSLDQGWTLCIQVLTSSCALDLDSACSAITYTIPVDQLGPGARREVTLPLGPGENGGLDLPVTVSCTLFYSLREVVGGALAPSDSEDPFLDECPSDVLPEQEGVCLPLSRHTVDMLQCLRFPGLAPPHTRAPSPLGPTRDPVATFLETCREPGSQPAGPASLRAEYLPPSVASIKVSAELLRAALKDGHSGVPLCCATLQWLLAENAAVDVVRARALSSIQGVAPDGANVHLIVREVAMTDLCPAGPIQAVEIQVESSSLADICRAHHAVVGRMQTMVTEQATQGSSAPDLRVQYLRQIHANHETLLREVQTLRDRLCTEDEASSCATAQRLLQVYRQLRHPSLILL"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/69394", 
                    "id": "69394", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A2ACJ2/", 
                    "id": "A2ACJ2", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "gene_name": "FAAP100", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }, 
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082256.2", 
        "ac": "NP_082256.2", 
        "name": "Fanconi anemia core complex-associated protein 100", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2ACJ2", 
                                "id": "A2ACJ2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "DNA binding", 
                        "id": "GO:0003677"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043240", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2ACJ2", 
                                "id": "A2ACJ2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "Fanconi anaemia nuclear complex", 
                        "id": "GO:0043240"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2ACJ2", 
                                "id": "A2ACJ2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleoplasm", 
                        "id": "GO:0005654"
                    }
                ], 
                "total": 2, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2ACJ2", 
                                "id": "A2ACJ2", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "interstrand cross-link repair", 
                        "id": "GO:0036297"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2ACJ2", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "2310003H01Rik"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2ACJ2", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Faap100"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2ACJ2", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Faap100"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000025384", 
            "id": "ENSMUSG00000025384", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/71885", 
            "id": "71885", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A2ACJ2*", 
            "id": "A2ACJ2", 
            "database": "IntAct"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029251", 
            "id": "IPR029251", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:71885", 
            "id": "mmu:71885", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:1919135", 
            "id": "1919135", 
            "database": "MGI"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/MQLFERP/", 
            "id": "MQLFERP", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=129283at2759", 
            "id": "129283at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14890", 
            "id": "PTHR14890", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF15146", 
            "id": "PF15146", 
            "database": "Pfam"
        }, 
        {
            "url": "http://purl.obolibrary.org/obo/PR_PR_A2ACJ2", 
            "id": "PR_A2ACJ2", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-6783310", 
            "id": "R-MMU-6783310", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082256", 
            "id": "NP_082256", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082256.2", 
            "id": "NP_082256.2", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2ACJ2", 
            "id": "A2ACJ2", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 94281.0, 
        "chemical_mass": 94281.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2ACJ2", 
            "name": "Faap100", 
            "locus": {
                "end_pos": 120369055, 
                "strand": "-", 
                "start_pos": 120378764, 
                "chromosome": "11", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000025384", 
                        "id": "ENSMUSG00000025384", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2ACJ2", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Fanconi anemia core complex-associated protein 100"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2ACJ2#names_and_taxonomy", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Fanconi anemia core complex-associated protein 100"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2ACJ2#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Fanconi anemia-associated protein of 100 kDa"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2ACJ2", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "fanconi anemia-associated protein of 100 kDa"
        }
    ]
}