{
    "uniprot_canonical_ac": "A6H909-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A6H909-1|TBPL2_RAT Isoform 1 of TATA box-binding protein-like 2  OS=Rattus norvegicus OX=10116 GN=Tbpl2 PE=2 SV=1 CANONICAL=A6H909-1", 
        "length": 344, 
        "sequence": "MEEDMYVDIFLDPYTFQDDFPPATSQLFSPGAPLDVHPLNPSNPETVFHSHLGAVKKAPSDFSSVDLSFLPDELTQENKDRTVTGNKVTNEESFRTQDWQSQLQLPDEQGSGLNLNSNSSPDTQSCLCSHDADSNQLSSETPNSNALPVVLISSMTPMNPVTECSGIVPQLQNVVSTANLACKLDLRKIALNAKNTEYNPKRFAAVIMRIREPRTTALIFSSGKVVCTGAKSEDESRLAARKYARVVQKLGFPVRFFNFKIQNMVASCDVKFPIRLEILALTHRQFSSYEPELFPGLIYKMVKPQVVLLIFASGKVVLTGAKERSEIYEAFENMYPILESFKKV"
    }, 
    "uniprot_id": "TBPL2_RAT", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Rat", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A6H909", 
                    "id": "A6H909", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/14634207", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "14634207"
                }
            ], 
            "title": "TRF3, a TATA-box-binding protein-related factor, is vertebrate-specific and widely expressed.", 
            "journal": "Proceedings of the National Academy of Sciences of the United States of America", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092831.1", 
                    "id": "NP_001092831.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Persengiev SP, Zhu X, Dixit BL, Maston GA, Kittler EL, Green MR", 
            "date": "2003"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/17570761", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "17570761"
                }
            ], 
            "title": "Genomics, evolution, and expression of TBPL2, a member of the TBP family.", 
            "journal": "DNA Cell Biol.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A6H909", 
                    "id": "A6H909", 
                    "database": "UniProtKB"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092831.1", 
                    "id": "NP_001092831.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Di Pietro V., Grzeschik K.H., Rinaldi A., Messina A., Grillo A., Angelica R., Barbagallo D., Buffa P., Calafato M.S., Carnemolla A., Caserta C., Di Pietro C., Duro L., Ferro A., Giugno R., Giunta V., Guglielmino M.R., Lagana A., Milicia I., Pulvirenti A., Purrello M., Ragusa M., Rapisarda A.", 
            "date": "2007"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/17641088", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "17641088"
                }
            ], 
            "title": "Analysis of TATA-binding protein 2 (TBP2) and TBP expression suggests different roles for the two proteins in regulation of gene expression during oogenesis and early mouse development.", 
            "journal": "Reproduction (Cambridge, England)", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092831.1", 
                    "id": "NP_001092831.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Gazdag E, Rajkovic A, Torres-Padilla ME, Tora L", 
            "date": "2007"
        }
    ], 
    "uniprot_ac": "A6H909", 
    "site_annotation": [
        {
            "end_pos": 120, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 118
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A6H909#A6H909-1", 
            "isoform_ac": "A6H909-1", 
            "locus": {
                "end_pos": 1095886, 
                "strand": "+", 
                "start_pos": 1116677, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000050371", 
                        "id": "ENSRNOT00000050371", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000039739", 
                        "id": "ENSRNOP00000039739", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A6H909-1|TBPL2_RAT Isoform 1 of TATA box-binding protein-like 2  OS=Rattus norvegicus OX=10116 GN=Tbpl2 PE=2 SV=1 CANONICAL=A6H909-1", 
                "length": 344, 
                "sequence": "MEEDMYVDIFLDPYTFQDDFPPATSQLFSPGAPLDVHPLNPSNPETVFHSHLGAVKKAPSDFSSVDLSFLPDELTQENKDRTVTGNKVTNEESFRTQDWQSQLQLPDEQGSGLNLNSNSSPDTQSCLCSHDADSNQLSSETPNSNALPVVLISSMTPMNPVTECSGIVPQLQNVVSTANLACKLDLRKIALNAKNTEYNPKRFAAVIMRIREPRTTALIFSSGKVVCTGAKSEDESRLAARKYARVVQKLGFPVRFFNFKIQNMVASCDVKFPIRLEILALTHRQFSSYEPELFPGLIYKMVKPQVVLLIFASGKVVLTGAKERSEIYEAFENMYPILESFKKV"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:680050", 
            "resource": "KEGG Pathway", 
            "id": "rno:680050", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A6H909#function", 
            "annotation": "Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity).", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A6H909#function", 
                    "id": "A6H909", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q6SJ95-1", 
            "protein_name": "TATA box-binding protein-like 2", 
            "sequence": {
                "length": 350, 
                "sequence": "MVGSLIMEEDIYLDLFLDPYTIQDDFPPAMSQLFSPGVPLDMHSLPSNPETVFHPHLGGVKKASTDFSSVDLSFLPDELTQENRDQTVTGNKLASEESCRTRDRQSQLQLPDEHGSELNLNSNSSPDPQSCLCFDDAHSNQPSPETPNSNALPVALIASMMPMNPVPGFSGIVPQLQNVVSTANLACKLDLRKIALNAKNTEYNPKRFAAVIMRIREPRTTALIFSSGKVVCTGAKSEEESRLAARKYARVVQKLGFPVRFFNFKIQNMVGSCDVKFPIRLEILALTHRQFSSSYEPELFPGLIYKMVKPQVVLLIFASGKVVLTGAKERSEIYEAFENMYPILESFKKV"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/133152", 
                    "id": "133152", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A6H909/", 
                    "id": "A6H909", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "gene_name": "Tbpl2", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q6SJ96-1", 
            "protein_name": "TATA box-binding protein-like 2", 
            "sequence": {
                "length": 375, 
                "sequence": "MASAPWPERVPRLLAPRLPSYPPPPPTVGLRSMEQEETYLELYLDQCAAQDGLAPPRSPLFSPVVPYDMYILNASNPDTAFNSNPEVKETSGDFSSVDLSFLPDEVTQENKDQPVISKHETEENSESQSPQSRLPSPSEQDVGLGLNSSSLSNSHSQLHPGDTDSVQPSPEKPNSDSLSLASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFKIQNMVGSCDVRFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYEAFENIYPILKGFKKA"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/133152", 
                    "id": "133152", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A6H909/", 
                    "id": "A6H909", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "gene_name": "TBPL2", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }, 
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092831.1", 
        "ac": "NP_001092831.1", 
        "name": "TATA box-binding protein-like 2", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016251", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A6H909", 
                                "id": "A6H909", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "RNA polymerase II general transcription initiation factor activity", 
                        "id": "GO:0016251"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A6H909", 
                                "id": "A6H909", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "DNA binding", 
                        "id": "GO:0003677"
                    }
                ], 
                "total": 2, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000790", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A6H909", 
                                "id": "A6H909", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nuclear chromatin", 
                        "id": "GO:0000790"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A6H909", 
                                "id": "A6H909", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleus", 
                        "id": "GO:0005634"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A6H909", 
                                "id": "A6H909", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }
                ], 
                "total": 3, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006352", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A6H909", 
                                "id": "A6H909", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "DNA-templated transcription, initiation", 
                        "id": "GO:0006352"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007275", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A6H909", 
                                "id": "A6H909", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "multicellular organism development", 
                        "id": "GO:0007275"
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A6H909", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Tbp2"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A6H909", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Tbpl2"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6H909", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Tbpl2"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6H909", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Trf3"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000033682", 
            "id": "ENSRNOG00000033682", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04516", 
            "id": "cd04516", 
            "database": "CDD"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/680050", 
            "id": "680050", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000814", 
            "id": "IPR000814", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR012295", 
            "id": "IPR012295", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR030491", 
            "id": "IPR030491", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR033710", 
            "id": "IPR033710", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:680050", 
            "id": "rno:680050", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/MEQEETY/", 
            "id": "MEQEETY", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=1219067at2759", 
            "id": "1219067at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10126", 
            "id": "PTHR10126", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00352", 
            "id": "PF00352", 
            "database": "Pfam"
        }, 
        {
            "url": "http://purl.obolibrary.org/obo/PR_PR_A6H909", 
            "id": "PR_A6H909", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092831.1", 
            "id": "NP_001092831.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1596837", 
            "id": "1596837", 
            "database": "RGD"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6H909", 
            "id": "A6H909", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [
        {
            "synonyms": [
                {
                    "id": "DOID:1289", 
                    "url": "http://disease-ontology.org/term/DOID:1289", 
                    "resource": "Disease Ontology", 
                    "name": "degenerative disease", 
                    "description": ""
                }
            ], 
            "recommended_name": {
                "id": "DOID:1289", 
                "url": "http://disease-ontology.org/term/DOID:1289", 
                "resource": "Disease Ontology", 
                "name": "neurodegenerative disease", 
                "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons."
            }, 
            "evidence": [
                {
                    "url": "https://www.alliancegenome.org/gene/1289#disease-associations", 
                    "id": "1289", 
                    "database": "Alliance of Genome Resources"
                }
            ]
        }
    ], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 38355.0, 
        "chemical_mass": 38355.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A6H909", 
            "name": "Tbpl2", 
            "locus": {
                "end_pos": 1095883, 
                "strand": "-", 
                "start_pos": 1116677, 
                "chromosome": "3", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000033682", 
                        "id": "ENSRNOG00000033682", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A6H909", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "TATA box-binding protein-like 2"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6H909#names_and_taxonomy", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "TATA box-binding protein-like 2"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A6H909", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "TATA box-binding protein-like protein 2; TBP-like protein 2; TBP-related factor 3; TATA box-binding protein-related factor 3; TBP-like 2"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6H909#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "TATA box-binding protein-related factor 3"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6H909#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "TBP-like 2"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6H909#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "TBP-related factor 3"
        }
    ]
}