{ "uniprot_canonical_ac": "A6H6S0-1", "ptm_annotation": [], "sequence": { "header": "tr|A6H6S0-1|A6H6S0_MOUSE Isoform 1 of Hect domain and RLD 3 OS=Mus musculus OX=10090 GN=Herc3 PE=1 SV=1 CANONICAL=A6H6S0-1", "length": 1050, "sequence": "MLCWGYWSLGQPGISSNLQGIVAEPQVCRFVSDRSIKEVACGGNHSVFLLEDGEVYTCGVNTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQTSPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSVNDEVNPRRVLELMGSEVTQIACGRQHTLALVPSSGLIYAFGCGAKGQLGTGHTCNVKCPSPVKGHWAAHSSQLSARADRFKYRVVKQIFSGGDQTFVLCSTYENSSPAVDFRTVNQTHYTNLINDETIAVWRQKLTEHNNANTVNGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRILFEKLMHSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLETNPSKVLDNWWSQACPKYFMKLVTLYKGAVLYLLRGRKTFLIPVLFNNYMTATLKLLEKLYKVNLKVKHVEYDKFYIPEISSLVDIQEDYLMWFLHQSGMKARPSIMQDAVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNHLVGDALRELSIHSDIDLKKPLKVIFDGEEGVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPSLEDLKELSPTEGRSLQELLDYPGEDIEETFCLNFTVCRESYGVIEQKKLIPGGDRVAVCKDNRQEFVDAYVNYIFQISVHEWYTAFSSGFLKVCGGKVLELFQPAELRAMMVGNSNYDWEELEETAVYRGDYSSTHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIIIQSTATGEEYLPVAHTCYNLLDLPKYSSKEIMKARLTQALDNYEGFSLA" }, "uniprot_id": "A6H6S0_MOUSE", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H6S0", "id": "A6H6S0", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/20799038", "type": [ "PubMed" ], "id": "20799038" } ], "title": "Optimising experimental design for high-throughput phenotyping in mice: a case study.", "journal": "Mammalian genome : official journal of the International Mammalian Genome Society", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082981.3", "id": "NP_082981.3", "database": "RefSeq" } ], "authors": "Karp NA, Baker LA, Gerdin AK, Adams NC, Ramirez-Solis R, White JK", "date": "2010" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/22790983", "type": [ "PubMed" ], "id": "22790983" } ], "title": "Epigenetic control of alternative mRNA processing at the imprinted Herc3/Nap1l5 locus.", "journal": "Nucleic acids research", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082981.3", "id": "NP_082981.3", "database": "RefSeq" } ], "authors": "Cowley M, Wood AJ, Bohm S, Schulz R, Oakey RJ", "date": "2012" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/24721909", "type": [ "PubMed" ], "id": "24721909" } ], "title": "Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen.", "journal": "Nature communications", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082981.3", "id": "NP_082981.3", "database": "RefSeq" } ], "authors": "Liakath-Ali K, Vancollie VE, Heath E, Smedley DP, Estabel J, Sunter D, Ditommaso T, White JK, Ramirez-Solis R, Smyth I, Steel KP, Watt FM", "date": "2014" } ], "uniprot_ac": "A6H6S0", "site_annotation": [ { "end_pos": 385, "annotation": "n_glycosylation_sequon", "start_pos": 383 }, { "end_pos": 396, "annotation": "n_glycosylation_sequon", "start_pos": 394 }, { "end_pos": 439, "annotation": "n_glycosylation_sequon", "start_pos": 437 }, { "end_pos": 46, "annotation": "n_glycosylation_sequon", "start_pos": 44 }, { "end_pos": 463, "annotation": "n_glycosylation_sequon", "start_pos": 461 }, { "end_pos": 803, "annotation": "n_glycosylation_sequon", "start_pos": 801 }, { "end_pos": 858, "annotation": "n_glycosylation_sequon", "start_pos": 856 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A6H6S0#A0A0N4SVW7-1", "isoform_ac": "A0A0N4SVW7-1", "locus": { "end_pos": 58843633, "strand": "-", "start_pos": 58843857, "chromosome": "6", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000203714", "id": "ENSMUST00000203714", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000145273", "id": "ENSMUSP00000145273", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0N4SVW7-1|A6H6S0_MOUSE Computationally mapped isoform of Hect domain and RLD 3 OS=Mus musculus OX=10090 GN=Herc3 PE=1 SV=2 CANONICAL=A6H6S0-1", "length": 75, "sequence": "MLCWGYWSLGQPGISSNLQGIVAEPQVCRFVSDRSIKEVACGGNHSVFLLEDGEVYTCGVNTKGQLGHEREGNKP" } }, { "url": "https://www.uniprot.org/uniprot/A6H6S0#A0A0N4SW02-1", "isoform_ac": "A0A0N4SW02-1", "locus": { "end_pos": 58890095, "strand": "-", "start_pos": 58902120, "chromosome": "6", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000204629", "id": "ENSMUST00000204629", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000145319", "id": "ENSMUSP00000145319", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0N4SW02-1|A6H6S0_MOUSE Computationally mapped isoform of Hect domain and RLD 3 OS=Mus musculus OX=10090 GN=Herc3 PE=1 SV=1 CANONICAL=A6H6S0-1", "length": 97, "sequence": "LIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPSLEDLKELSPTEGRSLQELLDYPGEDIEETFCLNFTVCRESYGVIEQKKLIPGGDRVAVCKDNR" } }, { "url": "https://www.uniprot.org/uniprot/A6H6S0#A6H6S0-1", "isoform_ac": "A6H6S0-1", "locus": { "end_pos": 58843633, "strand": "-", "start_pos": 58918918, "chromosome": "6", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000041401", "id": "ENSMUST00000041401", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000040025", "id": "ENSMUSP00000040025", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A6H6S0-1|A6H6S0_MOUSE Isoform 1 of Hect domain and RLD 3 OS=Mus musculus OX=10090 GN=Herc3 PE=1 SV=1 CANONICAL=A6H6S0-1", "length": 1050, "sequence": "MLCWGYWSLGQPGISSNLQGIVAEPQVCRFVSDRSIKEVACGGNHSVFLLEDGEVYTCGVNTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQTSPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSVNDEVNPRRVLELMGSEVTQIACGRQHTLALVPSSGLIYAFGCGAKGQLGTGHTCNVKCPSPVKGHWAAHSSQLSARADRFKYRVVKQIFSGGDQTFVLCSTYENSSPAVDFRTVNQTHYTNLINDETIAVWRQKLTEHNNANTVNGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRILFEKLMHSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLETNPSKVLDNWWSQACPKYFMKLVTLYKGAVLYLLRGRKTFLIPVLFNNYMTATLKLLEKLYKVNLKVKHVEYDKFYIPEISSLVDIQEDYLMWFLHQSGMKARPSIMQDAVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNHLVGDALRELSIHSDIDLKKPLKVIFDGEEGVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPSLEDLKELSPTEGRSLQELLDYPGEDIEETFCLNFTVCRESYGVIEQKKLIPGGDRVAVCKDNRQEFVDAYVNYIFQISVHEWYTAFSSGFLKVCGGKVLELFQPAELRAMMVGNSNYDWEELEETAVYRGDYSSTHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIIIQSTATGEEYLPVAHTCYNLLDLPKYSSKEIMKARLTQALDNYEGFSLA" } }, { "url": "https://www.uniprot.org/uniprot/A6H6S0#D3Z2S3-1", "isoform_ac": "D3Z2S3-1", "locus": { "end_pos": 58843633, "strand": "-", "start_pos": 58843713, "chromosome": "6", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000122981", "id": "ENSMUST00000122981", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000119115", "id": "ENSMUSP00000119115", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|D3Z2S3-1|A6H6S0_MOUSE Computationally mapped isoform of Hect domain and RLD 3 OS=Mus musculus OX=10090 GN=Herc3 PE=1 SV=1 CANONICAL=A6H6S0-1", "length": 27, "sequence": "MLCWGYWSLGQPGISSNLQGIVAEPQV" } }, { "url": "https://www.uniprot.org/uniprot/A6H6S0#D3Z3U0-1", "isoform_ac": "D3Z3U0-1", "locus": { "end_pos": 58843633, "strand": "-", "start_pos": 58843728, "chromosome": "6", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000141600", "id": "ENSMUST00000141600", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000122762", "id": "ENSMUSP00000122762", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|D3Z3U0-1|A6H6S0_MOUSE Computationally mapped isoform of Hect domain and RLD 3 OS=Mus musculus OX=10090 GN=Herc3 PE=1 SV=1 CANONICAL=A6H6S0-1", "length": 32, "sequence": "MLCWGYWSLGQPGISSNLQGIVAEPQVCRFVS" } }, { "url": "https://www.uniprot.org/uniprot/A6H6S0#D3Z6D4-1", "isoform_ac": "D3Z6D4-1", "locus": { "end_pos": 58843633, "strand": "-", "start_pos": 58854877, "chromosome": "6", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000126292", "id": "ENSMUST00000126292", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000122401", "id": "ENSMUSP00000122401", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|D3Z6D4-1|A6H6S0_MOUSE Computationally mapped isoform of Hect domain and RLD 3 OS=Mus musculus OX=10090 GN=Herc3 PE=1 SV=1 CANONICAL=A6H6S0-1", "length": 77, "sequence": "MLCWGYWSLGQPGISSNLQGIVAEPQVCRFVSDRSIKEVACGGNHSVFLLEDGEVYTCGVNTKGQLGHEREGNKPEQ" } }, { "url": "https://www.uniprot.org/uniprot/A6H6S0#G5E876-1", "isoform_ac": "G5E876-1", "locus": { "end_pos": 58843633, "strand": "-", "start_pos": 58903325, "chromosome": "6", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000031823", "id": "ENSMUST00000031823", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000031823", "id": "ENSMUSP00000031823", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|G5E876-1|A6H6S0_MOUSE Computationally mapped isoform of Hect domain and RLD 3 OS=Mus musculus OX=10090 GN=Herc3 PE=1 SV=1 CANONICAL=A6H6S0-1", "length": 913, "sequence": "MLCWGYWSLGQPGISSNLQGIVAEPQVCRFVSDRSIKEVACGGNHSVFLLEDGEVYTCGVNTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQTSPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSVNDEVNPRRVLELMGSEVTQIACGRQHTLALVPSSGLIYAFGCGAKGQLGTGHTCNVKCPSPVKGHWAAHSSQLSARADRFKYRVVKQIFSGGDQTFVLCSTYENSSPAVDFRTVNQTHYTNLINDETIAVWRQKLTEHNNANTVNGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRILFEKLMHSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLETNPSKVLDNWWSQACPKYFMKLVTLYKGAVLYLLRGRKTFLIPVLFNNYMTATLKLLEKLYKVNLKVKHVEYDKFYIPEISSLVDIQEDYLMWFLHQSGMKARPSIMQDAVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNHLVGDALRELSIHSDIDLKKPLKVIFDGEEGVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPSLEDLKELSPTEGRSLQELLDYPGEDIEETFCLNFTVCRESYGVIEQKKLIPGGDRVAVCKDNRQAQLRHQAFTVSLEGLQLPVSHTVIVY" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-983168", "resource": "Reactome", "id": "R-MMU-983168", "name": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "function": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082981.3", "annotation": "Allele-specific polyadenylation occurs at the imprinted Herc3/Nap1l5 locus.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082981.3", "id": "NP_082981.3", "database": "RefSeq" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZPP6-1", "protein_name": "HECT and RLD domain-containing E3 ubiquitin protein ligase 3", "sequence": { "length": 1050, "sequence": "MLCWGYWSLGQPGISSNLQGIVAEPQVCRFVSDRSIKEVACGGNHSVFLLEDGEVYTCGVNTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQTSPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSVNDEVNPRRVLELMGSEVTQIACGRQHTLALVPSSGLIYAFGCGAKGQLGTGHTCNVKCPSPVKGHWAAHSGQLSARADRFKYRVVKQIFSGGDQTFVLCSTYENSSPAVDFRTVNQAHYTNLINDETIAVWRQKLTEHNNANTVNGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMHSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLETNPSKVLDNWWSQACPKYFMKLVTLYKSAVLYLLRGRKTFLIPVLFNNYMTATLKLLEKLYKVNLKVKHVEYDKFYIPEISSLVDIQEDYLMWFLHQSGMKARPSIMQDAVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNHLVGDALRELSIHSDIDLKKPLKVIFDGEEGVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPSLEDLKELSPTEGRSLQELLDYPGEDIEETFCLNFTVCRESYGVIEQKKLIPGGDRVAVCKDNRQEFVDAYVNYIFQISVHEWYTAFSSGFLKVCGGKVLELFQPAELRAMMVGNSNYNWEELEETAVYKGDYSSTHPTVKLFWETFHEFPLEKKKRFLLFLTGSDRIPIYGMASLQIVIQSTATGEDYLPVAHTCYNLLDLPKYSSKEIMKARLTQALDNYEGFSLA" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/57095", "id": "57095", "database": "MGI" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "gene_name": "Herc3", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q15034-1", "protein_name": "Probable E3 ubiquitin-protein ligase HERC3", "sequence": { "length": 1050, "sequence": "MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGLNTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFKYHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNANTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILEQILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNPSKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKVNLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDTCFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQISVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHPTVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYNLLDLPKYSSKEILSARLTQALDNYEGFSLA" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/57095", "id": "57095", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A6H6S0/", "id": "A6H6S0", "database": "OMA" } ], "common_name": "Human", "organism": "Homo sapiens", "gene_name": "HERC3", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082981.3", "ac": "NP_082981.3", "name": "probable E3 ubiquitin-protein ligase HERC3 isoform a", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H6S0", "id": "A6H6S0", "database": "UniProtKB" } ], "name": "ubiquitin-protein transferase activity", "id": "GO:0004842" } ], "total": 1, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H6S0", "id": "A6H6S0", "database": "UniProtKB" } ], "name": "cytosol", "id": "GO:0005829" } ], "total": 1, "name": "Cellular Component" } ] }, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A6H6S0", "type": "synonym", "resource": "RefSeq", "name": "5730409F18Rik; AI646603; mKIAA0032" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A6H6S0", "type": "synonym", "resource": "RefSeq", "name": "Herc3" }, { "url": "https://www.uniprot.org/uniprot/A6H6S0", "type": "recommended", "resource": "UniProtKB", "name": "Herc3" } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000029804", "id": "ENSMUSG00000029804", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00078", "id": "cd00078", "database": "CDD" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/73998", "id": "73998", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000408", "id": "IPR000408", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", "id": "IPR000569", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR009091", "id": "IPR009091", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "id": "IPR035983", "database": "InterPro" }, { "url": "http://www.informatics.jax.org/marker/MGI:1921248", "id": "1921248", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/HVEYDAF/", "id": "HVEYDAF", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=1062377at2759", "id": "1062377at2759", "database": "OrthoDB" }, { "url": "http://pfam.xfam.org/family/PF00415", "id": "PF00415", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00632", "id": "PF00632", "database": "Pfam" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-983168", "id": "R-MMU-983168", "database": "Reactome" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_082981.3", "id": "NP_082981.3", "database": "RefSeq" }, { "url": "https://www.uniprot.org/uniprot/A6H6S0", "id": "A6H6S0", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 117356.0, "chemical_mass": 117356.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A6H6S0", "name": "Herc3", "locus": { "end_pos": 58920398, "strand": "+", "start_pos": 58831465, "chromosome": "6", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000029804", "id": "ENSMUSG00000029804", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A6H6S0#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "Hect domain and RLD 3" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A6H6S0", "type": "synonym", "resource": "RefSeq", "name": "probable E3 ubiquitin-protein ligase HERC3 isoform a" } ] }