{ "uniprot_canonical_ac": "A5D8V6-1", "ptm_annotation": [ { "annotation": "Phosphorylated by TBK1.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/pubmed/21270402", "id": "21270402", "database": "PubMed" } ] } ], "sequence": { "header": "sp|A5D8V6-1|VP37C_HUMAN Isoform 1 of Vacuolar protein sorting-associated protein 37C OS=Homo sapiens OX=9606 GN=VPS37C PE=1 SV=2 CANONICAL=A5D8V6-1", "length": 355, "sequence": "METLKDKTLQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEISRSNLSDRYQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAEKFLEGEVPLETFLENFSSMRMLSHLRRVRVEKLQEVVRKPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPGPAWPGY" }, "uniprot_id": "VP37C_HUMAN", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Human", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" } ], "name": "Homo sapiens", "taxid": 9606 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/11031247", "type": [ "PubMed" ], "id": "11031247" } ], "title": "Secretory protein trafficking and organelle dynamics in living cells.", "journal": "Annual review of cell and developmental biology", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_060436.4", "id": "NP_060436.4", "database": "RefSeq" } ], "authors": "Lippincott-Schwartz J, Roberts TH, Hirschberg K", "date": "2000" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/15218037", "type": [ "PubMed" ], "id": "15218037" } ], "title": "The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding.", "journal": "The Journal of biological chemistry", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_060436.4", "id": "NP_060436.4", "database": "RefSeq" } ], "authors": "Stuchell MD, Garrus JE, Muller B, Stray KM, Ghaffarian S, McKinnon R, Krausslich HG, Morham SG, Sundquist WI", "date": "2004" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/15509564", "type": [ "PubMed" ], "id": "15509564" } ], "title": "Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding.", "journal": "J. Biol. Chem.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_060436.4", "id": "NP_060436.4", "database": "RefSeq" } ], "authors": "Martin-Serrano J., Bieniasz P.D., Zang T., Chung W., Eastman S.W.", "date": "2005" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/17853893", "type": [ "PubMed" ], "id": "17853893" } ], "title": "Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis.", "journal": "EMBO J.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_060436.4", "id": "NP_060436.4", "database": "RefSeq" } ], "authors": "Gygi S.P., Morita E., Sandrin V., Sundquist W.I., Chung H.Y., Morham S.G., Rodesch C.K.", "date": "2007" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/18005716", "type": [ "PubMed" ], "id": "18005716" } ], "title": "Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding.", "journal": "Cell Host Microbe", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" } ], "authors": "Gygi S.P., Morita E., Eckert D.M., Sandrin V., Sundquist W.I., Alam S.L.", "date": "2007" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/21270402", "type": [ "PubMed" ], "id": "21270402" } ], "title": "TANK-binding kinase 1 attenuates PTAP-dependent retroviral budding through targeting endosomal sorting complex required for transport-I.", "journal": "J. Immunol.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" } ], "authors": "Yang X., Gao G., Tang H., Xu Y., Cheng G., Da Q.", "date": "2011" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/22405001", "type": [ "PubMed" ], "id": "22405001" } ], "title": "The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain.", "journal": "Structure", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_060436.4", "id": "NP_060436.4", "database": "RefSeq" } ], "authors": "Hofmann K., Ye Y., Allen M.D., Bycroft M., Freund S.M., Martin-Serrano J., Perisic O., Williams R.L., Agromayor M., Caballe A., Neil S.J., Scheel H., McDonald B., Kueck T., Soler N.", "date": "2012" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/23924735", "type": [ "PubMed" ], "id": "23924735" } ], "title": "VPS37 isoforms differentially modulate the ternary complex formation of ALIX, ALG-2, and ESCRT-I.", "journal": "Bioscience, biotechnology, and biochemistry", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_060436.4", "id": "NP_060436.4", "database": "RefSeq" } ], "authors": "Okumura M, Katsuyama AM, Shibata H, Maki M", "date": "2013" } ], "uniprot_ac": "A5D8V6", "site_annotation": [ { "end_pos": 137, "annotation": "n_glycosylation_sequon", "start_pos": 135 }, { "end_pos": 19, "annotation": "n_glycosylation_sequon", "start_pos": 17 }, { "end_pos": 48, "annotation": "n_glycosylation_sequon", "start_pos": 46 }, { "end_pos": 68, "annotation": "n_glycosylation_sequon", "start_pos": 66 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6#A5D8V6-1", "isoform_ac": "A5D8V6-1", "locus": { "end_pos": 61131823, "strand": "+", "start_pos": 61138829, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000301765", "id": "ENST00000301765", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000301765", "id": "ENSP00000301765", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A5D8V6-1|VP37C_HUMAN Isoform 1 of Vacuolar protein sorting-associated protein 37C OS=Homo sapiens OX=9606 GN=VPS37C PE=1 SV=2 CANONICAL=A5D8V6-1", "length": 355, "sequence": "METLKDKTLQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEISRSNLSDRYQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAEKFLEGEVPLETFLENFSSMRMLSHLRRVRVEKLQEVVRKPRASQELAGDAPPPRPPPPVRPVPQGTPPVVEEQPQPPLAMPPYPLPYSPSPSLPVGPTAHGALPPAPFPVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRSMPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQSPYPATGGKPPYPIQPQLPSFPGQPQPSVPLQPPYPPGPAPPYGFPPPPGPAWPGY" } }, { "url": "https://www.uniprot.org/uniprot/A5D8V6#F5H4Q5-1", "isoform_ac": "F5H4Q5-1", "locus": { "end_pos": 61132444, "strand": "+", "start_pos": 61138829, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000538036", "id": "ENST00000538036", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000446013", "id": "ENSP00000446013", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F5H4Q5-1|VP37C_HUMAN Computationally mapped isoform of Vacuolar protein sorting-associated protein 37C OS=Homo sapiens OX=9606 GN=VPS37C PE=1 SV=1 CANONICAL=A5D8V6-1", "length": 148, "sequence": "METLKDKTLQELEELQNDSEAIDQLALESPEVQDLQLEREMALATNRSLAERNLEFQGPLEISRSNLSDRYQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQVEGMKIEEESEAMAEKFLEGEVPLETFLENFSSMRMLSHLRRV" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:55048", "resource": "KEGG Pathway", "id": "hsa:55048", "name": "" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-162588", "resource": "Reactome", "id": "R-HSA-162588", "name": "Budding and maturation of HIV virion" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-174490", "resource": "Reactome", "id": "R-HSA-174490", "name": "Membrane binding and targetting of GAG proteins" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-917729", "resource": "Reactome", "id": "R-HSA-917729", "name": "Endosomal Sorting Complex Required For Transport (ESCRT)" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9610379", "resource": "Reactome", "id": "R-HSA-9610379", "name": "HCMV Late Events" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-9615710", "resource": "Reactome", "id": "R-HSA-9615710", "name": "Late endosomal microautophagy" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6#function", "annotation": "Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6#function", "id": "A5D8V6", "database": "UniProtKB" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_060436.4", "annotation": "VPS37B and appeared to interact with ALG-2 in a stronger manner than TSG101 does", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_060436.4", "id": "NP_060436.4", "database": "RefSeq" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_060436.4", "annotation": "VPS37C as a functional component of mammalian endosomal sorting complex required for transport-I", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_060436.4", "id": "NP_060436.4", "database": "RefSeq" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q8R105-1", "protein_name": "Vacuolar protein sorting-associated protein 37C", "sequence": { "length": 352, "sequence": "MEGLKDKTLQELEEMQNDPEAIARLALESPEVQDLQLEREMALATNRSLAEQNLEFQGPLEISRSNLSDKYQELRKLVERCQEQKAKLEKFSSALQPGTLLDLLQIEGMKIEEESEAMAEKFLEGEVPLETFLESFSSMRTLLHLRRVRVEKLQDVVRRPRALPELAGDVPPKRPPPPRPVPQATPPETEEQPPQPSVVTPYPLPYSPSPGLPVGPTAQGALQPAPFPVVAQPSSYGGPLGPYPSPHPGPRAMVGYSWSPQRSGPPQPGYPTAPTSTSGPGYPLVGGRTPGPGYPQQSPYLPSGNKPPYPTQPQLPGFPGQPQPPVPPQPPYPPGTTPSYGFHPPGPAWPRY" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A5D8V6/", "id": "A5D8V6", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/45637", "id": "45637", "database": "MGI" } ], "common_name": "Mouse", "organism": "Mus musculus", "gene_name": "Vps37c", "tax_id": 10090 } ], "interactions": [], "synthesized_glycans": [], "snv": [ { "sequence_org": "P", "start_pos": 178, "alt_nt": "A", "chr_id": "11", "ref_nt": "G", "chr_pos": "60899828", "disease": [ { "synonyms": [], "recommended_name": { "id": "DOID:1324", "url": "http://disease-ontology.org/term/DOID:1324", "resource": "Disease Ontology", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." } } ], "evidence": [ { "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A5D8V6", "id": "A5D8V6", "database": "BioMuta" } ], "glycoeffect": [], "frequency": "0.7", "sequence_mut": "S", "subjects_tested": "1514", "keywords": [ "biomuta", "somatic", "cancer", "disease" ], "annotation": "Somatic mutation passed 1 out of 6 filters: patient count (10/1514). In dbSNP: rs757821185.", "end_pos": 178, "minor_allelic_frequency": "", "subjects_positive": "10" }, { "sequence_org": "G", "start_pos": 288, "alt_nt": "A", "chr_id": "11", "ref_nt": "C", "chr_pos": "60899497", "disease": [ { "synonyms": [ { "id": "DOID:1612", "url": "http://disease-ontology.org/term/DOID:1612", "resource": "Disease Ontology", "name": "breast tumor", "description": "" }, { "id": "DOID:1612", "url": "http://disease-ontology.org/term/DOID:1612", "resource": "Disease Ontology", "name": "malignant neoplasm of breast", "description": "" }, { "id": "DOID:1612", "url": "http://disease-ontology.org/term/DOID:1612", "resource": "Disease Ontology", "name": "malignant tumor of the breast", "description": "" }, { "id": "DOID:1612", "url": "http://disease-ontology.org/term/DOID:1612", "resource": "Disease Ontology", "name": "mammary cancer", "description": "" }, { "id": "DOID:1612", "url": "http://disease-ontology.org/term/DOID:1612", "resource": "Disease Ontology", "name": "mammary tumor", "description": "" }, { "id": "DOID:1612", "url": "http://disease-ontology.org/term/DOID:1612", "resource": "Disease Ontology", "name": "primary breast cancer", "description": "" } ], "recommended_name": { "id": "DOID:1612", "url": "http://disease-ontology.org/term/DOID:1612", "resource": "Disease Ontology", "name": "breast cancer", "description": "A thoracic cancer that originates in the mammary gland." } } ], "evidence": [ { "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A5D8V6", "id": "A5D8V6", "database": "BioMuta" } ], "glycoeffect": [], "frequency": "2.0", "sequence_mut": "V", "subjects_tested": "50", "keywords": [ "biomuta", "somatic", "cancer", "disease" ], "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%).", "end_pos": 288, "minor_allelic_frequency": "", "subjects_positive": "1" }, { "sequence_org": "Q", "start_pos": 323, "alt_nt": "A", "chr_id": "11", "ref_nt": "C", "chr_pos": "60899391", "disease": [ { "synonyms": [ { "id": "DOID:1781", "url": "http://disease-ontology.org/term/DOID:1781", "resource": "Disease Ontology", "name": "Thyroid gland neoplasm", "description": "" }, { "id": "DOID:1781", "url": "http://disease-ontology.org/term/DOID:1781", "resource": "Disease Ontology", "name": "malignant neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "url": "http://disease-ontology.org/term/DOID:1781", "resource": "Disease Ontology", "name": "malignant tumour of thyroid gland", "description": "" }, { "id": "DOID:1781", "url": "http://disease-ontology.org/term/DOID:1781", "resource": "Disease Ontology", "name": "neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "url": "http://disease-ontology.org/term/DOID:1781", "resource": "Disease Ontology", "name": "thyroid neoplasm", "description": "" } ], "recommended_name": { "id": "DOID:1781", "url": "http://disease-ontology.org/term/DOID:1781", "resource": "Disease Ontology", "name": "thyroid gland cancer", "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage." } } ], "evidence": [ { "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A5D8V6", "id": "A5D8V6", "database": "BioMuta" } ], "glycoeffect": [], "frequency": "2.0", "sequence_mut": "H", "subjects_tested": "50", "keywords": [ "biomuta", "somatic", "cancer", "disease" ], "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%).", "end_pos": 323, "minor_allelic_frequency": "", "subjects_positive": "1" }, { "sequence_org": "Y", "start_pos": 342, "alt_nt": "G", "chr_id": "11", "ref_nt": "A", "chr_pos": "60899336", "disease": [ { "synonyms": [ { "id": "DOID:1781", "url": "http://disease-ontology.org/term/DOID:1781", "resource": "Disease Ontology", "name": "Thyroid gland neoplasm", "description": "" }, { "id": "DOID:1781", "url": "http://disease-ontology.org/term/DOID:1781", "resource": "Disease Ontology", "name": "malignant neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "url": "http://disease-ontology.org/term/DOID:1781", "resource": "Disease Ontology", "name": "malignant tumour of thyroid gland", "description": "" }, { "id": "DOID:1781", "url": "http://disease-ontology.org/term/DOID:1781", "resource": "Disease Ontology", "name": "neoplasm of thyroid gland", "description": "" }, { "id": "DOID:1781", "url": "http://disease-ontology.org/term/DOID:1781", "resource": "Disease Ontology", "name": "thyroid neoplasm", "description": "" } ], "recommended_name": { "id": "DOID:1781", "url": "http://disease-ontology.org/term/DOID:1781", "resource": "Disease Ontology", "name": "thyroid gland cancer", "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage." } } ], "evidence": [ { "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A5D8V6", "id": "A5D8V6", "database": "BioMuta" } ], "glycoeffect": [ "o-glyco-site-loss" ], "frequency": "2.0", "sequence_mut": "H", "subjects_tested": "50", "keywords": [ "biomuta", "somatic", "cancer", "disease" ], "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%).", "end_pos": 342, "minor_allelic_frequency": "", "subjects_positive": "1" } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_060436.4", "ac": "NP_060436.4", "name": "vacuolar protein sorting-associated protein 37C", "summary": "VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008]." }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "pmid": "23924735", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" } ], "name": "calcium-dependent protein binding", "id": "GO:0048306" } ], "total": 1, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" } ], "name": "intracellular membrane-bounded organelle", "id": "GO:0043231" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "pmid": "19056867", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" } ], "name": "extracellular exosome", "id": "GO:0070062" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "pmid": "23533145", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" } ], "name": "extracellular exosome", "id": "GO:0070062" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000813", "pmid": "18005716", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" } ], "name": "ESCRT I complex", "id": "GO:0000813" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000813", "pmid": "22405001", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" } ], "name": "ESCRT I complex", "id": "GO:0000813" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043657", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" } ], "name": "host cell", "id": "GO:0043657" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": "UniProtKB" } ], "name": "late endosome membrane", "id": "GO:0031902" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "id": "A5D8V6", "database": 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"ENSG00000167987", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002369", "uberon": "0002369", "name": "Adrenal gland" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000167987", "id": "ENSG00000167987", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0009853", "uberon": "0009853", "name": "Body of uterus" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000167987", "id": "ENSG00000167987", "database": "Bgee" } ] } ], "gene": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6", "name": "VPS37C", "locus": { "end_pos": 61130256, "strand": "-", "start_pos": 61161617, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSG00000167987", "id": "ENSG00000167987", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A5D8V6#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "ESCRT-I complex subunit VPS37C" }, { "url": "https://www.uniprot.org/uniprot/A5D8V6#names_and_taxonomy", "type": "recommended", "resource": "UniProtKB", "name": "Vacuolar protein sorting-associated protein 37C" }, { "url": "https://www.uniprot.org/uniprot/A5D8V6#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "hVps37C" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A5D8V6", "type": "synonym", "resource": "RefSeq", "name": "vacuolar protein sorting 37C; vacuolar protein sorting 37 homolog C; hVps37C; ESCRT-I complex subunit VPS37C; VPS37C, ESCRT-I subunit" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A5D8V6", "type": "synonym", "resource": "RefSeq", "name": "vacuolar protein sorting-associated protein 37C" } ] }