{
    "uniprot_canonical_ac": "A4D1N5-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A4D1N5-1|YG018_HUMAN Isoform 1 of Putative uncharacterized protein FLJ40288  OS=Homo sapiens OX=9606 GN= PE=2 SV=1 CANONICAL=A4D1N5-1", 
        "length": 150, 
        "sequence": "MSSRRSSLSPWKCPWFVYCFERPISREAGPVVHQSPTVLYLHSELAARQTQGRLLPREPAAEDLRLSLPGGHAALGLFKLQGKDSYPHPPTVLLGEDLSSSGWNSWVFGILNISRDEEAIGILTTILQLRETESSAVKWTHTKHSRELGP"
    }, 
    "uniprot_id": "YG018_HUMAN", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Human", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A4D1N5", 
                    "id": "A4D1N5", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "publication": [], 
    "uniprot_ac": "A4D1N5", 
    "site_annotation": [
        {
            "end_pos": 114, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 112
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A4D1N5#A4D1N5-1", 
            "isoform_ac": "A4D1N5-1", 
            "locus": {}, 
            "sequence": {
                "header": "sp|A4D1N5-1|YG018_HUMAN Isoform 1 of Putative uncharacterized protein FLJ40288  OS=Homo sapiens OX=9606 GN= PE=2 SV=1 CANONICAL=A4D1N5-1", 
                "length": 150, 
                "sequence": "MSSRRSSLSPWKCPWFVYCFERPISREAGPVVHQSPTVLYLHSELAARQTQGRLLPREPAAEDLRLSLPGGHAALGLFKLQGKDSYPHPPTVLLGEDLSSSGWNSWVFGILNISRDEEAIGILTTILQLRETESSAVKWTHTKHSRELGP"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [
        {
            "sequence_org": "I", 
            "start_pos": 122, 
            "alt_nt": "A", 
            "chr_id": "7", 
            "ref_nt": "T", 
            "chr_pos": "132412513", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:1612", 
                            "url": "http://disease-ontology.org/term/DOID:1612", 
                            "resource": "Disease Ontology", 
                            "name": "breast tumor", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1612", 
                            "url": "http://disease-ontology.org/term/DOID:1612", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of breast", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1612", 
                            "url": "http://disease-ontology.org/term/DOID:1612", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of the breast", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1612", 
                            "url": "http://disease-ontology.org/term/DOID:1612", 
                            "resource": "Disease Ontology", 
                            "name": "mammary cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1612", 
                            "url": "http://disease-ontology.org/term/DOID:1612", 
                            "resource": "Disease Ontology", 
                            "name": "mammary tumor", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1612", 
                            "url": "http://disease-ontology.org/term/DOID:1612", 
                            "resource": "Disease Ontology", 
                            "name": "primary breast cancer", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:1612", 
                        "url": "http://disease-ontology.org/term/DOID:1612", 
                        "resource": "Disease Ontology", 
                        "name": "breast cancer", 
                        "description": "A thoracic cancer that originates in the mammary gland."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A4D1N5", 
                    "id": "A4D1N5", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "2.0", 
            "sequence_mut": "K", 
            "subjects_tested": "50", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%).", 
            "end_pos": 122, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "K", 
            "start_pos": 138, 
            "alt_nt": "C", 
            "chr_id": "7", 
            "ref_nt": "A", 
            "chr_pos": "132412562", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "malignant Ovarian tumor", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumour of ovary", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "ovarian neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "ovary neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "primary ovarian cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "tumor of the Ovary", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:2394", 
                        "url": "http://disease-ontology.org/term/DOID:2394", 
                        "resource": "Disease Ontology", 
                        "name": "ovarian cancer", 
                        "description": "A female reproductive organ cancer that is located_in the ovary."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A4D1N5", 
                    "id": "A4D1N5", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [
                "n-glyco-sequon-gain", 
                "o-glyco-site-loss"
            ], 
            "frequency": "1.1", 
            "sequence_mut": "N", 
            "subjects_tested": "93", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (1.1%).", 
            "end_pos": 138, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }
    ], 
    "cluster_types": [], 
    "refseq": {}, 
    "go_annotation": {}, 
    "gene_names": [], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A4D1N5", 
            "id": "A4D1N5", 
            "database": "BioMuta"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A4D1N5", 
            "id": "NX_A4D1N5", 
            "database": "neXtProt"
        }, 
        {
            "url": "https://pharos.nih.gov/targets/A4D1N5", 
            "id": "A4D1N5", 
            "database": "PHAROS"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A4D1N5", 
            "id": "A4D1N5", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 16741.0, 
        "chemical_mass": 16741.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A4D1N5", 
            "name": "", 
            "locus": {}
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A4D1N5#names_and_taxonomy", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Putative uncharacterized protein FLJ40288"
        }
    ]
}