{
    "uniprot_canonical_ac": "A2RRD8-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A2RRD8-1|ZN320_HUMAN Isoform 1 of Zinc finger protein 320  OS=Homo sapiens OX=9606 GN=ZNF320 PE=1 SV=1 CANONICAL=A2RRD8-1", 
        "length": 509, 
        "sequence": "MALSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLDISSKCMMNTLSSTGQGNTEVIHTGTLQRQASYHIGAFCSQEIEKDIHDFVFQWQEDETNDHEAPMTEIKKLTSSTDRYDQRHAGNKPIKGQLESRFHLHLRRHRRIHTGEKPYKCEECEKVFSCKSHLEIHRIIHTGEKPYKCKVCDKAFKHDSHLAKHTRIHRGDKHYTCNECGKVFDQKATLACHHRSHTGEKPYKCNECGKTFSQTSHLVYHHRLHTGEKPYKCNECGKTFARNSVLVIHKAVHTAEKPYKCNECGKVFKQRATLAGHRRVHTGEKPYRCEECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRSDSRLAEHQRVHTGERPYTCNECGKVFSTKAYLACHQKLHTGEKLYECEECDKVYIRKSHLERHRRIHTGEKPHKCGDCGKAFNSPSHLIRHQRIHTGQKSYKCHQCGKVFSLRSLLAEHQKIPFGDNCFKCNEYSKPSSIN"
    }, 
    "uniprot_id": "ZN320_HUMAN", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Human", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2RRD8", 
                    "id": "A2RRD8", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/11536051", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "11536051"
                }
            ], 
            "title": "A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells.", 
            "journal": "Oncogene", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2RRD8", 
                    "id": "A2RRD8", 
                    "database": "UniProtKB"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997216.2", 
                    "id": "NP_997216.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Malaj E., Pan H., Cowell J.K., Roe B., Chernova O.B., Crooks C., Hunyadi A.", 
            "date": "2001"
        }
    ], 
    "uniprot_ac": "A2RRD8", 
    "site_annotation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RRD8#A0A669KBJ2-1", 
            "isoform_ac": "A0A669KBJ2-1", 
            "locus": {
                "end_pos": 52864032, 
                "strand": "+", 
                "start_pos": 52890255, 
                "chromosome": "19", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000673631", 
                        "id": "ENST00000673631", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000500974", 
                        "id": "ENSP00000500974", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A669KBJ2-1|ZN320_HUMAN Computationally mapped isoform of Zinc finger protein 320  OS=Homo sapiens OX=9606 GN=ZNF320 PE=1 SV=1 CANONICAL=A2RRD8-1", 
                "length": 117, 
                "sequence": "MALSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLGLISRDLCYLRKTPRRQRKGARDGSSSGILDFQRCGYRVLFAGVETPGPCTERFIQGCDVGELQEPGVCG"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RRD8#A2RRD8-1", 
            "isoform_ac": "A2RRD8-1", 
            "locus": {
                "end_pos": 52880599, 
                "strand": "+", 
                "start_pos": 52890255, 
                "chromosome": "19", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000595635", 
                        "id": "ENST00000595635", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000473091", 
                        "id": "ENSP00000473091", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2RRD8-1|ZN320_HUMAN Isoform 1 of Zinc finger protein 320  OS=Homo sapiens OX=9606 GN=ZNF320 PE=1 SV=1 CANONICAL=A2RRD8-1", 
                "length": 509, 
                "sequence": "MALSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLDISSKCMMNTLSSTGQGNTEVIHTGTLQRQASYHIGAFCSQEIEKDIHDFVFQWQEDETNDHEAPMTEIKKLTSSTDRYDQRHAGNKPIKGQLESRFHLHLRRHRRIHTGEKPYKCEECEKVFSCKSHLEIHRIIHTGEKPYKCKVCDKAFKHDSHLAKHTRIHRGDKHYTCNECGKVFDQKATLACHHRSHTGEKPYKCNECGKTFSQTSHLVYHHRLHTGEKPYKCNECGKTFARNSVLVIHKAVHTAEKPYKCNECGKVFKQRATLAGHRRVHTGEKPYRCEECDKVFSRKSHLERHRRIHTGEKPYKCKVCDKAFRSDSRLAEHQRVHTGERPYTCNECGKVFSTKAYLACHQKLHTGEKLYECEECDKVYIRKSHLERHRRIHTGEKPHKCGDCGKAFNSPSHLIRHQRIHTGQKSYKCHQCGKVFSLRSLLAEHQKIPFGDNCFKCNEYSKPSSIN"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RRD8#M0QX96-1", 
            "isoform_ac": "M0QX96-1", 
            "locus": {
                "end_pos": 52881619, 
                "strand": "+", 
                "start_pos": 52890255, 
                "chromosome": "19", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000597091", 
                        "id": "ENST00000597091", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000468995", 
                        "id": "ENSP00000468995", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|M0QX96-1|ZN320_HUMAN Computationally mapped isoform of Zinc finger protein 320  OS=Homo sapiens OX=9606 GN=ZNF320 PE=1 SV=1 CANONICAL=A2RRD8-1", 
                "length": 155, 
                "sequence": "MALSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLGQGNTEVIHTGTLQRQASYHIGAFCSQEIEKDIHDFVFQWQEDETNDHEAPMTEIKKLTSSTDRYDQRHAGNKPIKGQLESRFHLHLRRHRRIHTGEKPYKCEECEKV"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RRD8#M0QZA2-1", 
            "isoform_ac": "M0QZA2-1", 
            "locus": {
                "end_pos": 52881868, 
                "strand": "+", 
                "start_pos": 52890255, 
                "chromosome": "19", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000594741", 
                        "id": "ENST00000594741", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000470403", 
                        "id": "ENSP00000470403", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|M0QZA2-1|ZN320_HUMAN Computationally mapped isoform of Zinc finger protein 320  OS=Homo sapiens OX=9606 GN=ZNF320 PE=1 SV=1 CANONICAL=A2RRD8-1", 
                "length": 86, 
                "sequence": "MALSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLDISSKCMMNTLSSTGQGNTEVIHTGTLQRQASYHIGAFC"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RRD8#M0R0Z8-1", 
            "isoform_ac": "M0R0Z8-1", 
            "locus": {
                "end_pos": 52888194, 
                "strand": "+", 
                "start_pos": 52890255, 
                "chromosome": "19", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000597111", 
                        "id": "ENST00000597111", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000471548", 
                        "id": "ENSP00000471548", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|M0R0Z8-1|ZN320_HUMAN Computationally mapped isoform of Zinc finger protein 320  OS=Homo sapiens OX=9606 GN=ZNF320 PE=1 SV=1 CANONICAL=A2RRD8-1", 
                "length": 25, 
                "sequence": "MALSQGLLTFRDVAIEFSQEEWKCL"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RRD8#M0R1K6-1", 
            "isoform_ac": "M0R1K6-1", 
            "locus": {
                "end_pos": 52881955, 
                "strand": "+", 
                "start_pos": 52890255, 
                "chromosome": "19", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000597265", 
                        "id": "ENST00000597265", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000471938", 
                        "id": "ENSP00000471938", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|M0R1K6-1|ZN320_HUMAN Computationally mapped isoform of Zinc finger protein 320  OS=Homo sapiens OX=9606 GN=ZNF320 PE=1 SV=1 CANONICAL=A2RRD8-1", 
                "length": 57, 
                "sequence": "MALSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLDISSKCMMNT"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RRD8#M0R2L4-1", 
            "isoform_ac": "M0R2L4-1", 
            "locus": {
                "end_pos": 52881757, 
                "strand": "+", 
                "start_pos": 52890255, 
                "chromosome": "19", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000593618", 
                        "id": "ENST00000593618", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000472651", 
                        "id": "ENSP00000472651", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|M0R2L4-1|ZN320_HUMAN Computationally mapped isoform of Zinc finger protein 320  OS=Homo sapiens OX=9606 GN=ZNF320 PE=1 SV=1 CANONICAL=A2RRD8-1", 
                "length": 123, 
                "sequence": "MALSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLDISSKCMMNTLSSTGQGNTEVIHTGTLQRQASYHIGAFCSQEIEKDIHDFVFQWQEDETNDHEAPMTEIKKLTSST"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:162967", 
            "resource": "KEGG Pathway", 
            "id": "hsa:162967", 
            "name": ""
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-212436", 
            "resource": "Reactome", 
            "id": "R-HSA-212436", 
            "name": "Generic Transcription Pathway"
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RRD8#function", 
            "annotation": "May be involved in transcriptional regulation.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2RRD8#function", 
                    "id": "A2RRD8", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [
        {
            "sequence_org": "D", 
            "start_pos": 124, 
            "alt_nt": "G", 
            "chr_id": "19", 
            "ref_nt": "C", 
            "chr_pos": "53385009", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:11054", 
                            "url": "http://disease-ontology.org/term/DOID:11054", 
                            "resource": "Disease Ontology", 
                            "name": "bladder cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:11054", 
                            "url": "http://disease-ontology.org/term/DOID:11054", 
                            "resource": "Disease Ontology", 
                            "name": "tumor of the bladder", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:11054", 
                        "url": "http://disease-ontology.org/term/DOID:11054", 
                        "resource": "Disease Ontology", 
                        "name": "urinary bladder cancer", 
                        "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RRD8", 
                    "id": "A2RRD8", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "1.0", 
            "sequence_mut": "H", 
            "subjects_tested": "103", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (1.0%).", 
            "end_pos": 124, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "G", 
            "start_pos": 138, 
            "alt_nt": "T", 
            "chr_id": "19", 
            "ref_nt": "C", 
            "chr_pos": "53384967", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "malignant Ovarian tumor", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumour of ovary", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "ovarian neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "ovary neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "primary ovarian cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "tumor of the Ovary", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:2394", 
                        "url": "http://disease-ontology.org/term/DOID:2394", 
                        "resource": "Disease Ontology", 
                        "name": "ovarian cancer", 
                        "description": "A female reproductive organ cancer that is located_in the ovary."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RRD8", 
                    "id": "A2RRD8", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "1.1", 
            "sequence_mut": "S", 
            "subjects_tested": "93", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (1.1%). In dbSNP: rs748742438.", 
            "end_pos": 138, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "F", 
            "start_pos": 17, 
            "alt_nt": "T", 
            "chr_id": "19", 
            "ref_nt": "G", 
            "chr_pos": "53391471", 
            "disease": [
                {
                    "synonyms": [], 
                    "recommended_name": {
                        "id": "DOID:9256", 
                        "url": "http://disease-ontology.org/term/DOID:9256", 
                        "resource": "Disease Ontology", 
                        "name": "colorectal cancer", 
                        "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RRD8", 
                    "id": "A2RRD8", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "1.1", 
            "sequence_mut": "L", 
            "subjects_tested": "94", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (1.1%).", 
            "end_pos": 17, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "L", 
            "start_pos": 344, 
            "alt_nt": "C", 
            "chr_id": "19", 
            "ref_nt": "G", 
            "chr_pos": "53384349", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:11054", 
                            "url": "http://disease-ontology.org/term/DOID:11054", 
                            "resource": "Disease Ontology", 
                            "name": "bladder cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:11054", 
                            "url": "http://disease-ontology.org/term/DOID:11054", 
                            "resource": "Disease Ontology", 
                            "name": "tumor of the bladder", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:11054", 
                        "url": "http://disease-ontology.org/term/DOID:11054", 
                        "resource": "Disease Ontology", 
                        "name": "urinary bladder cancer", 
                        "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RRD8", 
                    "id": "A2RRD8", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "1.0", 
            "sequence_mut": "V", 
            "subjects_tested": "103", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (1.0%).", 
            "end_pos": 344, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "R", 
            "start_pos": 424, 
            "alt_nt": "T", 
            "chr_id": "19", 
            "ref_nt": "C", 
            "chr_pos": "53384108", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:10534", 
                            "url": "http://disease-ontology.org/term/DOID:10534", 
                            "resource": "Disease Ontology", 
                            "name": "gastric cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10534", 
                            "url": "http://disease-ontology.org/term/DOID:10534", 
                            "resource": "Disease Ontology", 
                            "name": "gastric neoplasm", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:10534", 
                        "url": "http://disease-ontology.org/term/DOID:10534", 
                        "resource": "Disease Ontology", 
                        "name": "stomach cancer", 
                        "description": "A gastrointestinal system cancer that is located_in the stomach."
                    }
                }, 
                {
                    "synonyms": [
                        {
                            "id": "DOID:1612", 
                            "url": "http://disease-ontology.org/term/DOID:1612", 
                            "resource": "Disease Ontology", 
                            "name": "breast tumor", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1612", 
                            "url": "http://disease-ontology.org/term/DOID:1612", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of breast", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1612", 
                            "url": "http://disease-ontology.org/term/DOID:1612", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of the breast", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1612", 
                            "url": "http://disease-ontology.org/term/DOID:1612", 
                            "resource": "Disease Ontology", 
                            "name": "mammary cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1612", 
                            "url": "http://disease-ontology.org/term/DOID:1612", 
                            "resource": "Disease Ontology", 
                            "name": "mammary tumor", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1612", 
                            "url": "http://disease-ontology.org/term/DOID:1612", 
                            "resource": "Disease Ontology", 
                            "name": "primary breast cancer", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:1612", 
                        "url": "http://disease-ontology.org/term/DOID:1612", 
                        "resource": "Disease Ontology", 
                        "name": "breast cancer", 
                        "description": "A thoracic cancer that originates in the mammary gland."
                    }
                }, 
                {
                    "synonyms": [
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "BT - Brain tumour", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "adult brain tumor", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "adult malignant brain neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "brain neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "brain neoplasm, adult", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "malignant brain tumour", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "malignant primary brain neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "malignant primary brain tumor", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of Brain", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of adult brain", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "neoplasm of brain", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "primary brain neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "primary brain tumor", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "primary malignant neoplasm of brain", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1319", 
                            "url": "http://disease-ontology.org/term/DOID:1319", 
                            "resource": "Disease Ontology", 
                            "name": "tumor of the Brain", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:1319", 
                        "url": "http://disease-ontology.org/term/DOID:1319", 
                        "resource": "Disease Ontology", 
                        "name": "brain cancer", 
                        "description": "A central nervous system cancer that is characterized by the growth of abnormal cells in the tissues of the brain."
                    }
                }, 
                {
                    "synonyms": [
                        {
                            "id": "DOID:4362", 
                            "url": "http://disease-ontology.org/term/DOID:4362", 
                            "resource": "Disease Ontology", 
                            "name": "cervical neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:4362", 
                            "url": "http://disease-ontology.org/term/DOID:4362", 
                            "resource": "Disease Ontology", 
                            "name": "cervix cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:4362", 
                            "url": "http://disease-ontology.org/term/DOID:4362", 
                            "resource": "Disease Ontology", 
                            "name": "cervix uteri cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:4362", 
                            "url": "http://disease-ontology.org/term/DOID:4362", 
                            "resource": "Disease Ontology", 
                            "name": "neoplasm of uterine cervix", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:4362", 
                            "url": "http://disease-ontology.org/term/DOID:4362", 
                            "resource": "Disease Ontology", 
                            "name": "tumor of the Cervix Uteri", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:4362", 
                            "url": "http://disease-ontology.org/term/DOID:4362", 
                            "resource": "Disease Ontology", 
                            "name": "uterine cervical neoplasm", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:4362", 
                        "url": "http://disease-ontology.org/term/DOID:4362", 
                        "resource": "Disease Ontology", 
                        "name": "cervical cancer", 
                        "description": "A female reproductive organ cancer that is located_in the cervix."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RRD8", 
                    "id": "A2RRD8", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "0.2", 
            "sequence_mut": "H", 
            "subjects_tested": "1044", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: num. of cancers (4).", 
            "end_pos": 424, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "2"
        }, 
        {
            "sequence_org": "Q", 
            "start_pos": 473, 
            "alt_nt": "T", 
            "chr_id": "19", 
            "ref_nt": "G", 
            "chr_pos": "53383962", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "malignant Ovarian tumor", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumour of ovary", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "ovarian neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "ovary neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "primary ovarian cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "tumor of the Ovary", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:2394", 
                        "url": "http://disease-ontology.org/term/DOID:2394", 
                        "resource": "Disease Ontology", 
                        "name": "ovarian cancer", 
                        "description": "A female reproductive organ cancer that is located_in the ovary."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RRD8", 
                    "id": "A2RRD8", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "1.1", 
            "sequence_mut": "K", 
            "subjects_tested": "93", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (1.1%).", 
            "end_pos": 473, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }
    ], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997216.2", 
        "ac": "NP_997216.2", 
        "name": "zinc finger protein 320 isoform 1", 
        "summary": "ZNF320 encodes a Kruppel-like zinc finger protein. Members of this protein family are involved in activation or repression of transcription.[supplied by OMIM, Jul 2002]."
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RRD8", 
                                "id": "A2RRD8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", 
                        "id": "GO:0000978"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RRD8", 
                                "id": "A2RRD8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", 
                        "id": "GO:0000981"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RRD8", 
                                "id": "A2RRD8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "metal ion binding", 
                        "id": "GO:0046872"
                    }
                ], 
                "total": 3, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RRD8", 
                                "id": "A2RRD8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleus", 
                        "id": "GO:0005634"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RRD8", 
                                "id": "A2RRD8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "regulation of transcription by RNA polymerase II", 
                        "id": "GO:0006357"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2RRD8", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "ZFPL"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2RRD8", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "ZNF320"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RRD8", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "ZNF320"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000182986", 
            "id": "ENSG00000182986", 
            "database": "Bgee"
        }, 
        {
            "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A2RRD8", 
            "id": "A2RRD8", 
            "database": "BioMuta"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", 
            "id": "cd07765", 
            "database": "CDD"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=ZNF320", 
            "id": "ZNF320", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/162967", 
            "id": "162967", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=13842", 
            "id": "13842", 
            "database": "HGNC"
        }, 
        {
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A2RRD8*", 
            "id": "A2RRD8", 
            "database": "IntAct"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", 
            "id": "IPR001909", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", 
            "id": "IPR013087", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", 
            "id": "IPR036051", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", 
            "id": "IPR036236", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:162967", 
            "id": "hsa:162967", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.omim.org/entry/606427", 
            "id": "606427", 
            "database": "MIM"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A2RRD8", 
            "id": "NX_A2RRD8", 
            "database": "neXtProt"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/YHIGALC/", 
            "id": "YHIGALC", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=1318335at2759", 
            "id": "1318335at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00096", 
            "id": "PF00096", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF01352", 
            "id": "PF01352", 
            "database": "Pfam"
        }, 
        {
            "url": "https://pharos.nih.gov/targets/A2RRD8", 
            "id": "A2RRD8", 
            "database": "PHAROS"
        }, 
        {
            "url": "http://purl.obolibrary.org/obo/PR_PR_A2RRD8", 
            "id": "PR_A2RRD8", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-212436", 
            "id": "R-HSA-212436", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_997216.2", 
            "id": "NP_997216.2", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RRD8", 
            "id": "A2RRD8", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [
        {
            "name": "Prostate cancer [DO disease name]", 
            "trend": "Up", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "NGP - new growth of prostate", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "hereditary prostate cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of the prostate", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "prostate cancer, familial", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "prostate neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "prostatic cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "prostatic neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "tumor of the prostate", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:10283", 
                        "url": "http://disease-ontology.org/term/DOID:10283", 
                        "resource": "Disease Ontology", 
                        "name": "prostate cancer", 
                        "description": "A male reproductive organ cancer that is located_in the prostate."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RRD8", 
                    "id": "A2RRD8", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:10283", 
            "significant": "No"
        }, 
        {
            "name": "Urinary bladder cancer [DO disease name]", 
            "trend": "Up", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:11054", 
                            "url": "http://disease-ontology.org/term/DOID:11054", 
                            "resource": "Disease Ontology", 
                            "name": "bladder cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:11054", 
                            "url": "http://disease-ontology.org/term/DOID:11054", 
                            "resource": "Disease Ontology", 
                            "name": "tumor of the bladder", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:11054", 
                        "url": "http://disease-ontology.org/term/DOID:11054", 
                        "resource": "Disease Ontology", 
                        "name": "urinary bladder cancer", 
                        "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RRD8", 
                    "id": "A2RRD8", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:11054", 
            "significant": "No"
        }, 
        {
            "name": "Thyroid gland cancer [DO disease name]", 
            "trend": "Up", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "Thyroid gland neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumour of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "thyroid neoplasm", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:1781", 
                        "url": "http://disease-ontology.org/term/DOID:1781", 
                        "resource": "Disease Ontology", 
                        "name": "thyroid gland cancer", 
                        "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RRD8", 
                    "id": "A2RRD8", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:1781", 
            "significant": "No"
        }, 
        {
            "name": "Liver cancer [DO disease name]", 
            "trend": "Up", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "Ca liver - primary", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "Resectable malignant neoplasm of Liver", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "hepatic cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "hepatic neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "malignant hepato-biliary neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of liver", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of liver, primary", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of liver", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "neoplasm of liver", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "non-resectable primary hepatic malignant neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "primary liver cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "primary malignant neoplasm of Liver", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "resectable malignant neoplasm of the liver", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of liver, not specified as primary or secondary", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
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                        "url": "http://disease-ontology.org/term/DOID:3571", 
                        "resource": "Disease Ontology", 
                        "name": "liver cancer", 
                        "description": "A hepatobiliary system cancer that is located_in the liver."
                    }
                }
            ], 
            "evidence": [
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                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A2RRD8", 
                    "id": "A2RRD8", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:3571", 
            "significant": "No"
        }, 
        {
            "name": "Lung squamous cell carcinoma [DO disease name]", 
            "trend": "Down", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:3907", 
                            "url": "http://disease-ontology.org/term/DOID:3907", 
                            "resource": "Disease Ontology", 
                            "name": "Epidermoid cell carcinoma of the lung", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
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                        "resource": "Disease Ontology", 
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            ], 
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                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:3907", 
            "significant": "No"
        }, 
        {
            "name": "Lung adenocarcinoma [DO disease name]", 
            "trend": "Down", 
            "disease": [
                {
                    "synonyms": [
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                            "id": "DOID:3910", 
                            "url": "http://disease-ontology.org/term/DOID:3910", 
                            "resource": "Disease Ontology", 
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                            "description": ""
                        }, 
                        {
                            "id": "DOID:3910", 
                            "url": "http://disease-ontology.org/term/DOID:3910", 
                            "resource": "Disease Ontology", 
                            "name": "nonsmall cell adenocarcinoma", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
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                        "url": "http://disease-ontology.org/term/DOID:3910", 
                        "resource": "Disease Ontology", 
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                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:3910", 
            "significant": "No"
        }, 
        {
            "name": "Esophageal cancer [DO disease name]", 
            "trend": "Up", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "Ca lower third oesophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "Ca middle third oesophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "esophagus cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of distal third of esophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of lower third of oesophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of middle third of oesophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of proximal third of esophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of upper third esophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of Distal Third of esophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of Proximal Third of esophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of abdominal esophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of the middle Third of the esophagus", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
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                        "url": "http://disease-ontology.org/term/DOID:5041", 
                        "resource": "Disease Ontology", 
                        "name": "esophageal cancer", 
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                    }
                }
            ], 
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                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:5041", 
            "significant": "No"
        }
    ], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 59326.0, 
        "chemical_mass": 59326.0
    }, 
    "expression_tissue": [
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            "evidence": [
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        {
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                "uberon": "0000458", 
                "name": "Endocervix"
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            "present": "yes", 
            "evidence": [
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                    "id": "ENSG00000182986", 
                    "database": "Bgee"
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        }, 
        {
            "tissue": {
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                "uberon": "0000473", 
                "name": "Testis"
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            "present": "yes", 
            "evidence": [
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                    "id": "ENSG00000182986", 
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        }, 
        {
            "tissue": {
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                "uberon": "0000948", 
                "name": "Heart"
            }, 
            "present": "yes", 
            "evidence": [
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                    "id": "ENSG00000182986", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000955", 
                "uberon": "0000955", 
                "name": "Brain"
            }, 
            "present": "yes", 
            "evidence": [
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                    "id": "ENSG00000182986", 
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            ]
        }, 
        {
            "tissue": {
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                "uberon": "0000992", 
                "name": "Ovary"
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            "present": "yes", 
            "evidence": [
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                    "id": "ENSG00000182986", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000996", 
                "uberon": "0000996", 
                "name": "Vagina"
            }, 
            "present": "yes", 
            "evidence": [
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                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000182986", 
                    "id": "ENSG00000182986", 
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001043", 
                "uberon": "0001043", 
                "name": "Esophagus"
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            "present": "yes", 
            "evidence": [
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                    "id": "ENSG00000182986", 
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            ]
        }, 
        {
            "tissue": {
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                "uberon": "0001150", 
                "name": "Body of pancreas"
            }, 
            "present": "yes", 
            "evidence": [
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                    "id": "ENSG00000182986", 
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001155", 
                "uberon": "0001155", 
                "name": "Colon"
            }, 
            "present": "yes", 
            "evidence": [
                {
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                    "id": "ENSG00000182986", 
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001160", 
                "uberon": "0001160", 
                "name": "Fundus of stomach"
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                    "id": "ENSG00000182986", 
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            ]
        }, 
        {
            "tissue": {
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                "uberon": "0001161", 
                "name": "Body of stomach"
            }, 
            "present": "yes", 
            "evidence": [
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                    "id": "ENSG00000182986", 
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001255", 
                "uberon": "0001255", 
                "name": "Urinary bladder"
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            "present": "yes", 
            "evidence": [
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                    "id": "ENSG00000182986", 
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001987", 
                "uberon": "0001987", 
                "name": "Placenta"
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            "present": "yes", 
            "evidence": [
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                    "id": "ENSG00000182986", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
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                "uberon": "0002046", 
                "name": "Thyroid gland"
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            "present": "yes", 
            "evidence": [
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                    "id": "ENSG00000182986", 
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        {
            "tissue": {
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                "uberon": "0002048", 
                "name": "Lung"
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        {
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                "uberon": "0002107", 
                "name": "Liver"
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            "evidence": [
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                    "id": "ENSG00000182986", 
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    ], 
    "gene": [
        {
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    "protein_names": [
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            "type": "recommended", 
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        }, 
        {
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            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "zinc finger protein like; zinc finger gene 320"
        }
    ]
}
