{ "uniprot_canonical_ac": "A2AQ19-1", "ptm_annotation": [], "sequence": { "header": "sp|A2AQ19-1|RTF1_MOUSE Isoform 1 of RNA polymerase-associated protein RTF1 homolog OS=Mus musculus OX=10090 GN=Rtf1 PE=1 SV=1 CANONICAL=A2AQ19-1", "length": 715, "sequence": "MRGRLCVGRAAAVAAAVAAAAVAVPLAGGQEGSQGGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKTRKVEKKGAMKKQANKAASSGSSDRDSSAESSAPEEGEVSDSESSSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEDDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMRNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMSKGQGKDKDLNSKTASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI" }, "uniprot_id": "RTF1_MOUSE", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/12520002", "type": [ "PubMed" ], "id": "12520002" } ], "title": "BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.", "journal": "Nucleic acids research", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084388.2", "id": "NP_084388.2", "database": "RefSeq" } ], "authors": "Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE", "date": "2003" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/15226823", "type": [ "PubMed" ], "id": "15226823" } ], "title": "Genomic analysis of mouse retinal development.", "journal": "PLoS biology", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084388.2", "id": "NP_084388.2", "database": "RefSeq" } ], "authors": "Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL", "date": "2004" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/17622165", "type": [ "PubMed" ], "id": "17622165" } ], "title": "A differential phosphoproteomic analysis of retinoic acid-treated P19 cells.", "journal": "J. Proteome Res.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "authors": "Figeys D., Smith J.C., Duchesne M.A., Ethier M., Tozzi P.", "date": "2007" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/18184592", "type": [ "PubMed" ], "id": "18184592" } ], "title": "Structure and DNA binding of the human Rtf1 Plus3 domain.", "journal": "Structure (London, England : 1993)", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084388.2", "id": "NP_084388.2", "database": "RefSeq" } ], "authors": "de Jong RN, Truffault V, Diercks T, Ab E, Daniels MA, Kaptein R, Folkers GE", "date": "2008" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/19345177", "type": [ "PubMed" ], "id": "19345177" } ], "title": "A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.", "journal": "Cell Stem Cell", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084388.2", "id": "NP_084388.2", "database": "RefSeq" } ], "authors": "Ding L., Pisabarro M.T., Shevchenko A., Buchholz F., Heninger A.K., Junqueira M., Paszkowski-Rogacz M., Poser I., Theis M., Slabicki M.M., Stewart A.F., Kittler R., Schulz H., Hubner N., Anastassiadis K., Caldarelli A., Doss M.X., Hescheler J., Iacone R., Nitzsche A., Sachinidis A., de Vries I.", "date": "2009" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/24036311", "type": [ "PubMed" ], "id": "24036311" } ], "title": "CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development.", "journal": "Developmental biology", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084388.2", "id": "NP_084388.2", "database": "RefSeq" } ], "authors": "Zhang K, Haversat JM, Mager J", "date": "2013" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/27749823", "type": [ "PubMed" ], "id": "27749823" } ], "title": "Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.", "journal": "Nat. Cell Biol.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084388.2", "id": "NP_084388.2", "database": "RefSeq" } ], "authors": "Yang Y., Dolgalev I., Strahl B.D., Strikoudis A., Buckley S., Dynlacht B.D., Stadtfeld M., Aifantis I., Galvao Neto A.L., Lazaris C., Ntziachristos P., Rothbart S., Trimarchi T., Tsirigos A.", "date": "2016" } ], "uniprot_ac": "A2AQ19", "site_annotation": [ { "end_pos": 301, "annotation": "n_glycosylation_sequon", "start_pos": 299 }, { "end_pos": 563, "annotation": "n_glycosylation_sequon", "start_pos": 561 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19#A2AQ19-1", "isoform_ac": "A2AQ19-1", "locus": { "end_pos": 119675068, "strand": "-", "start_pos": 119732888, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000028767", "id": "ENSMUST00000028767", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000028767", "id": "ENSMUSP00000028767", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2AQ19-1|RTF1_MOUSE Isoform 1 of RNA polymerase-associated protein RTF1 homolog OS=Mus musculus OX=10090 GN=Rtf1 PE=1 SV=1 CANONICAL=A2AQ19-1", "length": 715, "sequence": "MRGRLCVGRAAAVAAAVAAAAVAVPLAGGQEGSQGGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKTRKVEKKGAMKKQANKAASSGSSDRDSSAESSAPEEGEVSDSESSSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEDDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMRNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMSKGQGKDKDLNSKTASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:76246", "resource": "KEGG Pathway", "id": "mmu:76246", "name": "" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-112382", "resource": "Reactome", "id": "R-MMU-112382", "name": "Formation of RNA Pol II elongation complex" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-674695", "resource": "Reactome", "id": "R-MMU-674695", "name": "RNA Polymerase II Pre-transcription Events" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-75955", "resource": "Reactome", "id": "R-MMU-75955", "name": "RNA Polymerase II Transcription Elongation" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8866654", "resource": "Reactome", "id": "R-MMU-8866654", "name": "E3 ubiquitin ligases ubiquitinate target proteins" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19#function", "annotation": "Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both independently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3' end formation probably through association with cleavage and poly(A) factors. Binds single-stranded DNA (By similarity). Required for maximal induction of heat-shock genes. Required for the trimethylation of histone H3 'Lys-4' (H3K4me3) on genes involved in stem cell pluripotency; this function is synergistic with CXXC1 indicative for an involvement of a SET1 complex.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19#function", "id": "A2AQ19", "database": "UniProtKB" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084388.2", "annotation": "Potential role of Rtf1 Plus single stranded DNA binding during transcription elongation.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084388.2", "id": "NP_084388.2", "database": "RefSeq" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q92541-1", "protein_name": "RNA polymerase-associated protein RTF1 homolog", "sequence": { "length": 710, "sequence": "MRGRLCVGRAAAAAAAVAVPLAGGQEGSPGGGRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMKNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMSKGQGKDKDLNSKSASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/133868", "id": "133868", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A2AQ19/", "id": "A2AQ19", "database": "OMA" } ], "common_name": "Human", "organism": "Homo sapiens", "gene_name": "RTF1", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084388.2", "ac": "NP_084388.2", "name": "RNA polymerase-associated protein RTF1 homolog precursor", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990269", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "name": "RNA polymerase II C-terminal domain phosphoserine binding", "id": "GO:1990269" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "name": "single-stranded DNA binding", "id": "GO:0003697" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "pmid": "9701556", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "name": "nucleolus", "id": "GO:0005730" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016593", "pmid": "27749823", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "name": "Cdc73/Paf1 complex", "id": "GO:0016593" } ], "total": 2, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "pmid": "19345177", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019827", "pmid": "19345177", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "name": "stem cell population maintenance", "id": "GO:0019827" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080182", "pmid": "19345177", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "name": "histone H3-K4 trimethylation", "id": "GO:0080182" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051571", "pmid": "19345177", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "name": "positive regulation of histone H3-K4 methylation", "id": "GO:0051571" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001832", "pmid": "24036311", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "name": "blastocyst growth", "id": "GO:0001832" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001711", "pmid": "19345177", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "name": "endodermal cell fate commitment", "id": "GO:0001711" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "name": "Wnt signaling pathway", "id": "GO:0016055" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006368", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "name": "transcription elongation from RNA polymerase II promoter", "id": "GO:0006368" } ], "total": 8, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AQ19", "type": "synonym", "resource": "RefSeq", "name": "2900005O08Rik; 6530416A09Rik; AI853581; AU043144; AW553985; cbp82; Gtl; Gtl7" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AQ19", "type": "synonym", "resource": "RefSeq", "name": "Rtf1" }, { "url": "https://www.uniprot.org/uniprot/A2AQ19", "type": "recommended", "resource": "UniProtKB", "name": "Rtf1" } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000027304", "id": "ENSMUSG00000027304", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/76246", "id": "76246", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/intact/interactors/id:A2AQ19*", "id": "A2AQ19", "database": "IntAct" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR004343", "id": "IPR004343", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036128", "id": "IPR036128", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:76246", "id": "mmu:76246", "database": "KEGG Pathway" }, { "url": "http://www.informatics.jax.org/marker/MGI:1309480", "id": "1309480", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/SGCKSAV/", "id": "SGCKSAV", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=607093at2759", "id": "607093at2759", "database": "OrthoDB" }, { "url": "http://pfam.xfam.org/family/PF03126", "id": "PF03126", "database": "Pfam" }, { "url": "http://purl.obolibrary.org/obo/PR_PR_A2AQ19", "id": "PR_A2AQ19", "database": "PRO" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-112382", "id": "R-MMU-112382", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-674695", "id": "R-MMU-674695", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-75955", "id": "R-MMU-75955", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8866654", "id": "R-MMU-8866654", "database": "Reactome" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084388.2", "id": "NP_084388.2", "database": "RefSeq" }, { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [ { "residue": "Ser", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "start_pos": "58", "end_pos": "58", "kinase_uniprot_canonical_ac": "" }, { "residue": "Thr", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "start_pos": "60", "end_pos": "60", "kinase_uniprot_canonical_ac": "" }, { "residue": "Ser", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "start_pos": "631", "end_pos": "631", "kinase_uniprot_canonical_ac": "" }, { "residue": "Ser", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "start_pos": "660", "end_pos": "660", "kinase_uniprot_canonical_ac": "" }, { "residue": "Ser", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "id": "A2AQ19", "database": "UniProtKB" } ], "start_pos": "702", "end_pos": "702", "kinase_uniprot_canonical_ac": "" } ], "mass": { "monoisotopic_mass": 80797.0, "chemical_mass": 80797.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A2AQ19", "name": "Rtf1", "locus": { "end_pos": 119735407, "strand": "+", "start_pos": 119675068, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000027304", "id": "ENSMUSG00000027304", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AQ19", "type": "synonym", "resource": "RefSeq", "name": "RNA polymerase-associated protein RTF1 homolog precursor" }, { "url": "https://www.uniprot.org/uniprot/A2AQ19#names_and_taxonomy", "type": "recommended", "resource": "UniProtKB", "name": "RNA polymerase-associated protein RTF1 homolog" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AQ19", "type": "synonym", "resource": "RefSeq", "name": "gene trap locus 7; Rtf1, Paf1/RNA polymerase II complex component, homolog; RNA polymerase-associated protein RTF1 homolog" } ] }