{ "uniprot_canonical_ac": "A2AG50-1", "ptm_annotation": [], "sequence": { "header": "sp|A2AG50-1|MA7D2_MOUSE Isoform 1 of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1", "length": 781, "sequence": "MERSGGNGGGGGGGGGGGGGYGGSGGGGGGAGVPSEGAAKGLSLLLAKSAEAASGRASQSTPRSAGMDGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKCSWAGSPGPGGRDGESENTPPLPLTLATSTPPLDTGTTTAAAESTNACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEMAYKREQEKKRQEEEEKRKAEEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDASLEVKKEDPKVELQPPPDVENKANKAKPVVPNKIEINVLNTCQKVSGSERAAPETFPQDIFSTGLKPVGGPVHLDVLDGKSNSLDDSTEDVQSMDVSPVSKEELISIPEFSPVSEMIPGMSLDQNGTGNARALQDILDFTGPPAFPKKSSENLSLDDCNKNLIEGFNSPGQETTLNTFC" }, "uniprot_id": "MA7D2_MOUSE", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AG50", "id": "A2AG50", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/16452087", "type": [ "PubMed" ], "id": "16452087" } ], "title": "Comprehensive identification of phosphorylation sites in postsynaptic density preparations.", "journal": "Mol. Cell. Proteomics", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AG50", "id": "A2AG50", "database": "UniProtKB" } ], "authors": "Schoepfer R., Burlingame A.L., Thalhammer A., Specht C.G., Trinidad J.C.", "date": "2006" } ], "uniprot_ac": "A2AG50", "site_annotation": [ { "end_pos": 729, "annotation": "n_glycosylation_sequon", "start_pos": 727 }, { "end_pos": 756, "annotation": "n_glycosylation_sequon", "start_pos": 754 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2AG50#A2AG50-1", "isoform_ac": "A2AG50-1", "locus": { "end_pos": 159414697, "strand": "-", "start_pos": 159496281, "chromosome": "X", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000112471", "id": "ENSMUST00000112471", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000108090", "id": "ENSMUSP00000108090", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2AG50-1|MA7D2_MOUSE Isoform 1 of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1", "length": 781, "sequence": "MERSGGNGGGGGGGGGGGGGYGGSGGGGGGAGVPSEGAAKGLSLLLAKSAEAASGRASQSTPRSAGMDGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKCSWAGSPGPGGRDGESENTPPLPLTLATSTPPLDTGTTTAAAESTNACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEMAYKREQEKKRQEEEEKRKAEEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDASLEVKKEDPKVELQPPPDVENKANKAKPVVPNKIEINVLNTCQKVSGSERAAPETFPQDIFSTGLKPVGGPVHLDVLDGKSNSLDDSTEDVQSMDVSPVSKEELISIPEFSPVSEMIPGMSLDQNGTGNARALQDILDFTGPPAFPKKSSENLSLDDCNKNLIEGFNSPGQETTLNTFC" } }, { "url": "https://www.uniprot.org/uniprot/A2AG50#A2AG50-2", "isoform_ac": "A2AG50-2", "locus": { "end_pos": 159459393, "strand": "-", "start_pos": 159496281, "chromosome": "X", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000043151", "id": "ENSMUST00000043151", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000046693", "id": "ENSMUSP00000046693", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2AG50-2|MA7D2_MOUSE Isoform 2 of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1", "length": 597, "sequence": "MMRRSLERTQQLELKKKCSWAGSPGPGGRDACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEMAYKREQEKKRQEEEEKRKAEEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDASLEVKKEDPKVELQPPPDVENKANKAKPVVPNKIEINVLNTCQKVSGSERAAPETFPQDIFSTGLKPVGGPVHLDVLDGKSNSLDDSTEDVQSMDVSPVSKEELISIPEFSPVSEMIPGMSLDQNGTGNARALQDILDFTGPPAFPKKSSENLSLDDCNKNLIEGFNSPGQETTLNTFC" } }, { "url": "https://www.uniprot.org/uniprot/A2AG50#A2AG50-3", "isoform_ac": "A2AG50-3", "locus": { "end_pos": 159459393, "strand": "-", "start_pos": 159486429, "chromosome": "X", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000112470", "id": "ENSMUST00000112470", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000108089", "id": "ENSMUSP00000108089", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2AG50-3|MA7D2_MOUSE Isoform 3 of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1", "length": 296, "sequence": "MMRRSLERTQQLELKKKCSWAGSPGPGGRDACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERM" } }, { "url": "https://www.uniprot.org/uniprot/A2AG50#A2AG51-1", "isoform_ac": "A2AG51-1", "locus": { "end_pos": 159459393, "strand": "-", "start_pos": 159490778, "chromosome": "X", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000145142", "id": "ENSMUST00000145142", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000122106", "id": "ENSMUSP00000122106", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A2AG51-1|MA7D2_MOUSE Computationally mapped isoform of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=2 CANONICAL=A2AG50-1", "length": 402, "sequence": "MMRRSLERTQQLELKKKCSWAGSPGPGGRDACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEMAYKREQEKKRQEEEEKRKAEEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLER" } }, { "url": "https://www.uniprot.org/uniprot/A2AG50#Q8C0A6-1", "isoform_ac": "Q8C0A6-1", "locus": { "end_pos": 159459393, "strand": "-", "start_pos": 159470093, "chromosome": "X", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000156172", "id": "ENSMUST00000156172", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000119132", "id": "ENSMUSP00000119132", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|Q8C0A6-1|MA7D2_MOUSE Computationally mapped isoform of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1", "length": 74, "sequence": "MMRRSLERTQQLELKKKCSWAGSPGPGGRDALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQ" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:78283", "resource": "KEGG Pathway", "id": "mmu:78283", "name": "" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "D4A4L4-1", "protein_name": "MAP7 domain-containing 2", "sequence": { "length": 715, "sequence": "MDGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKCSWAGSAASGPGGRDGESENTPPLPLTLAASIPPSDTGTATAAAESTNACDKLSTSTMNLPKQTEPPMSKHLSSSIVAISYSPDRALRSPLKSSYKSSPTRTTEKKKNTLLSGVGDAGKGAMTGGEPSQMEKVKKGRGATSVSSGGLGSPLRRCEPPENISKRSSSPVKSKVTAKTYPQSPKTVKPTYIGSPVKYYFPPTPSEETLKKKAEKEKSNKEKEGATGRQTTVLPREETLEKPMADKDATEKYVADKHATEKHSATGGKAEHSAGKSTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEEQERLEKEELKRKAEEERLRIEKQEEEKKQQEEEEKRKAEEKAKEKAEEELLSKEEQEKEKQEKEKKEKAMIEKQIQAEKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDASLEVKKEDPKVEIQPLPDVENKIKPVVPNKIEINVLNTCQKVNVSERAAPETFPQDIFSNGLKPVGGPVHPDVLDGKSNSLDDSTEEVQSMDVSPVSKEELISIPEFSPVSEMIPGMSLDQNGTGNARALQDILDFTGPPAFPKKSSENLSLDDCNKNLIEGFNSPGQETTLNTFC" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A2AG50/", "id": "A2AG50", "database": "OMA" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "gene_name": "Map7d2", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q96T17-1", "protein_name": "MAP7 domain-containing protein 2", "sequence": { "length": 732, "sequence": "MERGGGGSGTGSRPEGTARGTSLPGKIAEPGAVRTSQPNYRPQGMEGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKYSWGAPLAIGPGGHDACDKLSTSTMSLPKPTEPPMNKRLSSSTVAISYSPDRVFHVCPRLAPLGPLNPSYKSSPTRNIEKKKATSTSTSGAGDVGKEALSGGEASLVEKVKRGQRTATSLPVVNFGSPLRRCEFSGGIPKRPSSPVISKTATKAYPQSPKTTKPPYPGSPVKYRLPALSGQDMPKRKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASEKHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDVSPQVKKEDPKVGVQPAVCVEKKTKLVVPNKMEINGLNTCQEVNGVDHAAPETYPQDIFSNGLKPAGGLIHLDALDGKSNSLDDSTEEVQSMDVSPVSKEELISIPEFSPVSEMIPGVSLDQNGTGNARALQDLLDFTGPPTFPKRSSENLSLDDCNKNLIEGFNSPGQETPLNTFC" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/45149", "id": "45149", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "gene_name": "MAP7D2", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593.1", "ac": "NP_001074593.1", "name": "MAP7 domain-containing protein 2 isoform 1", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AG50", "id": "A2AG50", "database": "UniProtKB" } ], "name": "microtubule cytoskeleton", "id": "GO:0015630" } ], "total": 1, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AG50", "id": "A2AG50", "database": "UniProtKB" } ], "name": "microtubule cytoskeleton organization", "id": "GO:0000226" } ], "total": 1, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AG50", "type": "synonym", "resource": "RefSeq", "name": "1600028E09Rik; 2900002G04Rik; 5330432J06Rik; C030036K04Rik; Mtap7; Mtap7d2" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AG50", "type": "synonym", "resource": "RefSeq", "name": "Map7d2" }, { "url": "https://www.uniprot.org/uniprot/A2AG50", "type": "recommended", "resource": "UniProtKB", "name": "Map7d2" }, { "url": "https://www.uniprot.org/uniprot/A2AG50", "type": "synonym", "resource": "UniProtKB", "name": "Mtap7d2" } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000041020", "id": "ENSMUSG00000041020", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/78283", "id": "78283", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR008604", "id": "IPR008604", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:78283", "id": "mmu:78283", "database": "KEGG Pathway" }, { "url": "http://www.informatics.jax.org/marker/MGI:1917474", "id": "1917474", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/SPVKYRF/", "id": "SPVKYRF", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=265189at2759", "id": "265189at2759", "database": "OrthoDB" }, { "url": "http://pfam.xfam.org/family/PF05672", "id": "PF05672", "database": "Pfam" }, { "url": "http://purl.obolibrary.org/obo/PR_PR_A2AG50", "id": "PR_A2AG50", "database": "PRO" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593.1", "id": "NP_001074593.1", "database": "RefSeq" }, { "url": "https://www.uniprot.org/uniprot/A2AG50", "id": "A2AG50", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [ { "residue": "Ser", "kinase_gene_name": "Atxn7l3b", "evidence": [ { "url": "http://phospho.elm.eu.org/byAccession/A2AG50.html", "id": "A2AG50", "database": "phospho.ELM" }, { "url": "https://www.ncbi.nlm.nih.gov/pubmed/16452087", "id": "16452087", "database": "PubMed" } ], "start_pos": "248", "end_pos": "248", "kinase_uniprot_canonical_ac": "Q3UD01-1" } ], "mass": { "monoisotopic_mass": 86050.0, "chemical_mass": 86050.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A2AG50", "name": "Map7d2", "locus": { "end_pos": 159498757, "strand": "+", "start_pos": 159414572, "chromosome": "X", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000041020", "id": "ENSMUSG00000041020", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AG50", "type": "synonym", "resource": "RefSeq", "name": "MAP7 domain-containing protein 2 isoform 1" }, { "url": "https://www.uniprot.org/uniprot/A2AG50#names_and_taxonomy", "type": "recommended", "resource": "UniProtKB", "name": "MAP7 domain-containing protein 2" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AG50", "type": "synonym", "resource": "RefSeq", "name": "novel E-MAP-115 family protein; MAP7 domain-containing protein 2" } ] }