{
    "uniprot_canonical_ac": "A2A8C4-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A2A8C4-1|A2A8C4_MOUSE Isoform 1 of Predicted gene 13057  OS=Mus musculus OX=10090 GN=Gm13040 PE=3 SV=1 CANONICAL=A2A8C4-1", 
        "length": 496, 
        "sequence": "MRISDQVYSLYRFIRMSFQAPPTLLSLAVQSLAKNEALAINALQELPRELFPPLFKAAFTGRHTKILKEMVGAWPLPCLPVGALMNVPDMTILQAVLDGVDMQLTGNFHPRKRKLQVLDLRNVHHHFWDVSAGPEDGDGSAETVCQKQKATRPHSYALRRRLKVVTDLCLQFDLEEHQTYFLQWAQERRGSLNLCCVKMQIRELPLHTVRKILQIFQPYCIEELELHIDWTLSTLASFAPCLGQIKNLRKLHLTLVHEKLFTFLCTSTDIKEKSVTKFISQFSKLNSLQHLDLAGLYFLTGHMNELLVCLKTPLEFLSIALCKYSQSDMESFAQCQSLHHLKHLHLAGVILHDLSLVPLGIFLENVANTLKTLELEHCRMTDSQVSAFIPALNKCSQLIEVNFCDNDISMPVLTNLLHHTANLSQLIMELYPAPLECYETGFVLRPERIVQLSSELMNILCTVRQPHSICFASQLCLICSQRCTYGLETRLCHCCQ"
    }, 
    "uniprot_id": "A2A8C4_MOUSE", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2A8C4", 
                    "id": "A2A8C4", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "publication": [], 
    "uniprot_ac": "A2A8C4", 
    "site_annotation": [
        {
            "end_pos": 424, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 422
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A8C4#A2A8C4-1", 
            "isoform_ac": "A2A8C4-1", 
            "locus": {
                "end_pos": 143551728, 
                "strand": "-", 
                "start_pos": 143557648, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000105776", 
                        "id": "ENSMUST00000105776", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000101402", 
                        "id": "ENSMUSP00000101402", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A2A8C4-1|A2A8C4_MOUSE Isoform 1 of Predicted gene 13057  OS=Mus musculus OX=10090 GN=Gm13040 PE=3 SV=1 CANONICAL=A2A8C4-1", 
                "length": 496, 
                "sequence": "MRISDQVYSLYRFIRMSFQAPPTLLSLAVQSLAKNEALAINALQELPRELFPPLFKAAFTGRHTKILKEMVGAWPLPCLPVGALMNVPDMTILQAVLDGVDMQLTGNFHPRKRKLQVLDLRNVHHHFWDVSAGPEDGDGSAETVCQKQKATRPHSYALRRRLKVVTDLCLQFDLEEHQTYFLQWAQERRGSLNLCCVKMQIRELPLHTVRKILQIFQPYCIEELELHIDWTLSTLASFAPCLGQIKNLRKLHLTLVHEKLFTFLCTSTDIKEKSVTKFISQFSKLNSLQHLDLAGLYFLTGHMNELLVCLKTPLEFLSIALCKYSQSDMESFAQCQSLHHLKHLHLAGVILHDLSLVPLGIFLENVANTLKTLELEHCRMTDSQVSAFIPALNKCSQLIEVNFCDNDISMPVLTNLLHHTANLSQLIMELYPAPLECYETGFVLRPERIVQLSSELMNILCTVRQPHSICFASQLCLICSQRCTYGLETRLCHCCQ"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A8C4#Q4FZF9-1", 
            "isoform_ac": "Q4FZF9-1", 
            "locus": {
                "end_pos": 143515047, 
                "strand": "-", 
                "start_pos": 143517245, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000178489", 
                        "id": "ENSMUST00000178489", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000137329", 
                        "id": "ENSMUSP00000137329", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|Q4FZF9-1|A2A8C4_MOUSE Computationally mapped isoform of Predicted gene 13057  OS=Mus musculus OX=10090 GN=Gm13040 PE=3 SV=1 CANONICAL=A2A8C4-1", 
                "length": 481, 
                "sequence": "MSFQAPPTLLSLAVQSLAKNEALAINALQELPRELFPPLFKAAFTGRHTKILKEMVGAWPLPCLPVGALMNVPDMTILQAVLDGVDMQLTGNFHPRKRKLQVLDLRNVHHHFWDVSAGPEDGDGSAETVCQKQKATRPHSYALRRRLKVVTDLCLQFDLEEHQTYFLQWAQERRGSLNLCCVKMQIRELPLHTVRKILQIFQPYCIEELELHIDWTLSTLASFAPCLGQIKNLRKLHLTLVHEKLFTFLCTSTDIKEKSVTKFISQFSKLNSLQHLDLAGLYFLTGHMNELLVCLKTPLEFLSIALCKYSQSDMESFAQCQSLHHLKHLHLAGVILHDLSLVPLGIFLENVANTLKTLELEHCRMTDSQVSAFIPALNKCSQLIEVNFCDNDISMPVLTNLLHHTANLSQLIMELYPAPLECYETGFVLRPERIVQLSSELMNILCTVRQPHSICFASQLCLICSQRCTYGLETRLCHCCQ"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:100040854", 
            "resource": "KEGG Pathway", 
            "id": "mmu:100040854", 
            "name": ""
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:100040861", 
            "resource": "KEGG Pathway", 
            "id": "mmu:100040861", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "A2ASI9-1", 
            "protein_name": "PRAME-like 16", 
            "sequence": {
                "length": 494, 
                "sequence": "MLQQVYSLYRFIRMSFQDPPTLLSLAVQSLVKNEALAINALQELPRELFPPLFKAAFTGRHTKILKEMVGSWPLLCLPVGALMNVPDMSILQAVLDGVDMQLTGNFHPRKRKLQVLDLRNVHHHFWDVSAGPEDGDGSAETVCQKQKATRPHRYALRRRLKVVTDLCLQFDLEEHQTYFLQWAQERRCSLNLCCVKMQIRELPIHTVRKILQIFQPYCIEELELNTGWTLSTLACFTPCLGQMKNLRKLHLTLVHEKLFTFLRTSTDIQEKSVTKFISQFSKLNSLQHLNLTGLYFLTGHINELLGCLKTPLEFLSIALCKYSQSDMESFAQCQSLHHLKHLHLAGIILHDLSLVPLGIFLENVANTLKTLELEHCRMTDSQVSAFIPALNKCSQLIEVNFCDNDISTSVLMNLLHHTANLSQLIMELYPAPLECYETGFVLRAERFVQLSSELMNILCTVRQPHSICFASQLCLICSQRCTYGLETRLCHCCQ"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/83161", 
                    "id": "83161", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "gene_name": "Pramel16", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "B1ARV5-1", 
            "protein_name": "PRAME-like 31", 
            "sequence": {
                "length": 481, 
                "sequence": "MSFQAPPTLLSLAVQSLAKNEALAINALQELPRELFPPLFKAAFTGRHTKILKEMVGAWPLPCLPVGALMNIPDMTVLQAVLDGVDMQLTGNFHPSKRKLQVLDLRNVHHHFWDVSAGPEDEDSSAETVCQKQKATHPHRYALRRRLKVVTDLHLQFDLEEHQTYFLQWAQERRASLNLCCVKLQIRGLAMHTVRKILQIFQPYCIEELELNTGWTLSTLACFAPCLGQMKNLRKLHLTLVHEKLFTFLHTSTDIQEKSVTKFISQFSKLNSLQHLALAGLYFLTGHMNELLGCLKTPLEFLSMALCKYSQSDMESFAQCQSLHHLKHLHLAGIILHDLSLVPLGIFLENVANTLKTLELEHCRMTDSQVIAFIPALNKCSQLIEVNFCDNDISTSVLMNLLHHTANLSQLIMELYPAPLECYETGFVLRAERFVQLSSELMNILRTVRQPHSICFASQLCLICSQRCTYGLETRLCHCCQ"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/83161", 
                    "id": "83161", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "gene_name": "Pramel31", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q66JY9-1", 
            "protein_name": "PRAME-like 20", 
            "sequence": {
                "length": 481, 
                "sequence": "MSFQAPPTLLSLAVQSLAKNEALAINALQELPRELYPPLFKAAFIDRHTRILKEMVGAWPLPCLPVGALMNVPDMTVLQAVLDGVDMQLTGKFHPRKRKLQVLDLRNVHHHFWDVSAGPEDGDGSAETVCQKQKATRPHRYALRRRLKVVTDLCLQFYLEEHQTYFLQWAQERRGSLNLCCVKMQIRELPMHTVRKILQIFQPYCIEELELHIGWTQSTLACFAPCLGQMKNLRKLHLTLVHEKLFTFLCTSTDIQEKSVTKFISQFSKLNSLRHLDLAGLYFLTGHMNELLGCLKTPLEFLSIALCKYSQSDMESFAQCQSLHHLKHLHLAGVILHDLSLVPLGIFLENVANTLKTLELEHCRMTDSQVSAFIPALNKCSQLIEVNFCDNDISMPVLTNLLHHTANLSQLIMELYPAPLECYETGFVLRPERIVQLSSELMNILCTVRQPHSICFASQLCLICSQRCTYGLETRLCHCCQ"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/83161", 
                    "id": "83161", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "gene_name": "Pramel20", 
            "tax_id": 10090
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107207.1", 
        "ac": "NP_001107207.1", 
        "name": "pramel family member", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8C4", 
                                "id": "A2A8C4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008284", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8C4", 
                                "id": "A2A8C4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of cell population proliferation", 
                        "id": "GO:0008284"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8C4", 
                                "id": "A2A8C4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "negative regulation of apoptotic process", 
                        "id": "GO:0043066"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8C4", 
                                "id": "A2A8C4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "negative regulation of transcription, DNA-templated", 
                        "id": "GO:0045892"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045596", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2A8C4", 
                                "id": "A2A8C4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "negative regulation of cell differentiation", 
                        "id": "GO:0045596"
                    }
                ], 
                "total": 4, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A8C4", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Gm13040"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2A8C4", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Gm13057"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A8C4", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Gm13057"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000070616", 
            "id": "ENSMUSG00000070616", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/100040854", 
            "id": "100040854", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/100040861", 
            "id": "100040861", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR026271", 
            "id": "IPR026271", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", 
            "id": "IPR032675", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:100040854", 
            "id": "mmu:100040854", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:100040861", 
            "id": "mmu:100040861", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:3649498", 
            "id": "3649498", 
            "database": "MGI"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:3649690", 
            "id": "3649690", 
            "database": "MGI"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/CLKIPLY/", 
            "id": "CLKIPLY", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=563553at2759", 
            "id": "563553at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107207.1", 
            "id": "NP_001107207.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A8C4", 
            "id": "A2A8C4", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 56561.0, 
        "chemical_mass": 56561.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A8C4", 
            "name": "Gm13040", 
            "locus": {
                "end_pos": 143542471, 
                "strand": "+", 
                "start_pos": 143535954, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000070616", 
                        "id": "ENSMUSG00000070616", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2A8C4#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Predicted gene 13040"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2A8C4#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Predicted gene 13057"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2A8C4", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "pramel family member"
        }
    ]
}