{ "uniprot_canonical_ac": "A2A870-1", "ptm_annotation": [], "sequence": { "header": "sp|A2A870-1|FBF1_MOUSE Isoform 1 of Fas-binding factor 1 OS=Mus musculus OX=10090 GN=Fbf1 PE=1 SV=1 CANONICAL=A2A870-1", "length": 1173, "sequence": "MTGQCCEELQRAPKPRMALRTKKGLKGSIEDVLGDLLGDDTTPPEKPAEPASHAKDTASSPQWQASKAKFLPKDSVEGLAGADAEASSVSDADPQVFLQNMKDLDSMDDDLFGRMKSHQPSGKGAAKGPGKEGPSNHKPAGTLTANEKGYTMPTKKPPPSSSKTGLQYKKFSFEDFEDPLAGLLSDEEEETATKLPAVERKPAPKSPGAAAGQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKAERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFQLDKKYQKMGGEESVPARDKEDSWDDETLTFGAYKPTVASSEGRQSRRQSVSRFLGEGGPDPKGESLGFKQSSPPASSPIHPRKGGADWLGLKDNDLDLLSPSPVQKAQQEDSPMTPSLLPPTNQPSAPEPQSAPTGLPSAAKPPAKGARPSLKASQASSPKASEEKEDDWLSHVISQKKSQNLAREERAGPPKDLASLGSLGQTPSGSLPVAQVLEQAPAGEASKPTTQGMAAVRPGVTGSSMSWSQATTVLPVDDPKKGAASASGDFSSREPAVYIPHSQEPTGLSVPIQTLLPESMMQSLLPGSGYQKQLLAAQGQLQSSTAQLQVELLQSQTKLSELEAQVRKLELERAQHRMLLESLQQRHQADLELIEDAHRSRIKVLETSYQQREEQLRREKEVLSAQHASYCREAEQARAELVAQHQRQMAMAEQERDQEVARLRELQQASILEMRKDHEHQLQRLKMLKDQEIDAVTSATSHTRSLNGIIEQMEKFSSSLNTLSSRVEASHLTTSQQRELGIRQQDEQLRALQERLGRQQRDMEEERNRLQEVIGKMEVRLSEQSRLLEQERWRVAAEKTKAESAQRTLEEQRKIMVQQIAMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERAMHADSQREGTIISLTKEQAELTVRACELRAKEEKLLAEREALERERQELRLEKDRLHKASLRLQARAQEVEHMSKVASKKYEEGEQALQEAQQMQNEQQGRLQVVQRQQEWLRQQEQRVHQEHLSLAQQRLQLDRVRQEVPASLPGLPPRVQGPAASSRDAVQAPASSSPQCSQPAAAQVPTHLLAKLLLLKHTAEEDHDFLENEQFFLETLKKAPYNMAYHSA" }, "uniprot_id": "FBF1_MOUSE", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/10978533", "type": [ "PubMed" ], "id": "10978533" } ], "title": "A novel protein (Fbf-1) that binds to CD95/APO-1/FAS and shows sequence similarity to trichohyalin and plectin.", "journal": "Biochim. Biophys. Acta", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "authors": "Schmidt T., Moeroey T., Baum W., Denzel A., Frass B., Karsunky H.", "date": "2000" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/12520002", "type": [ "PubMed" ], "id": "12520002" } ], "title": "BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.", "journal": "Nucleic acids research", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766159.3", "id": "NP_766159.3", "database": "RefSeq" } ], "authors": "Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE", "date": "2003" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/12819125", "type": [ "PubMed" ], "id": "12819125" } ], "title": "Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.", "journal": "Genome research", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766159.3", "id": "NP_766159.3", "database": "RefSeq" } ], "authors": "Carninci P, Waki K, Shiraki T, Konno H, Shibata K, Itoh M, Aizawa K, Arakawa T, Ishii Y, Sasaki D, Bono H, Kondo S, Sugahara Y, Saito R, Osato N, Fukuda S, Sato K, Watahiki A, Hirozane-Kishikawa T, Nakamura M, Shibata Y, Yasunishi A, Kikuchi N, Yoshiki A, Kusakabe M, Gustincich S, Beisel K, Pavan W, Aidinis V, Nakagawara A, Held WA, Iwata H, Kono T, Nakauchi H, Lyons P, Wells C, Hume DA, Fagiolini M, Hensch TK, Brinkmeier M, Camper S, Hirota J, Mombaerts P, Muramatsu M, Okazaki Y, Kawai J, Hayashizaki Y", "date": "2003" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/18218630", "type": [ "PubMed" ], "id": "18218630" } ], "title": "G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator.", "journal": "The Journal of biological chemistry", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766159.3", "id": "NP_766159.3", "database": "RefSeq" } ], "authors": "Zhang D, Harry GJ, Blackshear PJ, Zeldin DC", "date": "2008" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/18838552", "type": [ "PubMed" ], "id": "18838552" } ], "title": "The keratin-binding protein Albatross regulates polarization of epithelial cells.", "journal": "The Journal of cell biology", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766159.3", "id": "NP_766159.3", "database": "RefSeq" } ], "authors": "Sugimoto M, Inoko A, Shiromizu T, Nakayama M, Zou P, Yonemura S, Hayashi Y, Izawa I, Sasoh M, Uji Y, Kaibuchi K, Kiyono T, Inagaki M", "date": "2008" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/24469809", "type": [ "PubMed" ], "id": "24469809" } ], "title": "C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766159.3", "id": "NP_766159.3", "database": "RefSeq" } ], "authors": "Ye X, Zeng H, Ning G, Reiter JF, Liu A", "date": "2014" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/30318703", "type": [ "PubMed" ], "id": "30318703" } ], "title": "Albatross/FBF1 contributes to both centriole duplication and centrosome separation.", "journal": "Genes to cells : devoted to molecular & cellular mechanisms", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766159.3", "id": "NP_766159.3", "database": "RefSeq" } ], "authors": "Inoko A, Yano T, Miyamoto T, Matsuura S, Kiyono T, Goshima N, Inagaki M, Hayashi Y", "date": "2018" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/30626697", "type": [ "PubMed" ], "id": "30626697" } ], "title": "Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766159.3", "id": "NP_766159.3", "database": "RefSeq" } ], "authors": "Ding W, Wu Q, Sun L, Pan NC, Wang X", "date": "2019" } ], "uniprot_ac": "A2A870", "site_annotation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2A870#A2A870-1", "isoform_ac": "A2A870-1", "locus": { "end_pos": 116143386, "strand": "+", "start_pos": 116165882, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000106435", "id": "ENSMUST00000106435", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000102043", "id": "ENSMUSP00000102043", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2A870-1|FBF1_MOUSE Isoform 1 of Fas-binding factor 1 OS=Mus musculus OX=10090 GN=Fbf1 PE=1 SV=1 CANONICAL=A2A870-1", "length": 1173, "sequence": "MTGQCCEELQRAPKPRMALRTKKGLKGSIEDVLGDLLGDDTTPPEKPAEPASHAKDTASSPQWQASKAKFLPKDSVEGLAGADAEASSVSDADPQVFLQNMKDLDSMDDDLFGRMKSHQPSGKGAAKGPGKEGPSNHKPAGTLTANEKGYTMPTKKPPPSSSKTGLQYKKFSFEDFEDPLAGLLSDEEEETATKLPAVERKPAPKSPGAAAGQGPSVPLTPGDTPIRKKELLFDEGDDIMTTLGFEDSPKAERKKTGDQEGPLPARSKLDELLGRGTAAKLLTRPGTGERREFQLDKKYQKMGGEESVPARDKEDSWDDETLTFGAYKPTVASSEGRQSRRQSVSRFLGEGGPDPKGESLGFKQSSPPASSPIHPRKGGADWLGLKDNDLDLLSPSPVQKAQQEDSPMTPSLLPPTNQPSAPEPQSAPTGLPSAAKPPAKGARPSLKASQASSPKASEEKEDDWLSHVISQKKSQNLAREERAGPPKDLASLGSLGQTPSGSLPVAQVLEQAPAGEASKPTTQGMAAVRPGVTGSSMSWSQATTVLPVDDPKKGAASASGDFSSREPAVYIPHSQEPTGLSVPIQTLLPESMMQSLLPGSGYQKQLLAAQGQLQSSTAQLQVELLQSQTKLSELEAQVRKLELERAQHRMLLESLQQRHQADLELIEDAHRSRIKVLETSYQQREEQLRREKEVLSAQHASYCREAEQARAELVAQHQRQMAMAEQERDQEVARLRELQQASILEMRKDHEHQLQRLKMLKDQEIDAVTSATSHTRSLNGIIEQMEKFSSSLNTLSSRVEASHLTTSQQRELGIRQQDEQLRALQERLGRQQRDMEEERNRLQEVIGKMEVRLSEQSRLLEQERWRVAAEKTKAESAQRTLEEQRKIMVQQIAMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERAMHADSQREGTIISLTKEQAELTVRACELRAKEEKLLAEREALERERQELRLEKDRLHKASLRLQARAQEVEHMSKVASKKYEEGEQALQEAQQMQNEQQGRLQVVQRQQEWLRQQEQRVHQEHLSLAQQRLQLDRVRQEVPASLPGLPPRVQGPAASSRDAVQAPASSSPQCSQPAAAQVPTHLLAKLLLLKHTAEEDHDFLENEQFFLETLKKAPYNMAYHSA" } }, { "url": "https://www.uniprot.org/uniprot/A2A870#A2A870-2", "isoform_ac": "A2A870-2", "locus": {}, "sequence": { "header": "sp|A2A870-2|FBF1_MOUSE Isoform 2 of Fas-binding factor 1 OS=Mus musculus OX=10090 GN=Fbf1 PE=1 SV=1 CANONICAL=A2A870-1", "length": 389, "sequence": "MEKFSSSLNTLSSRVEASHLTTSQQRELGIRQQDEQLRALQERLGRQQRDMEEERNRLQEVIGKMEVRLSEQSRLLEQERWRVAAEKTKAESAQRTLEEQRKIMVQQIAMEREELERAKSALLEEQKSVMNKCGEERRRLAAEWAEYFTQQKLSKERAEREAERAMHADSQREGTIISLTKEQAELTVRACELRAKEEKLLAEREALERERQELRLEKDRLHKASLRLQARAQEVEHMSKVASKKYEEGEQALQEAQQMQNEQQGRLQVVQRQQEWLRQQEQRVHQEHLSLAQQRLQLDRVRQEVPASLPGLPPRVQGPAASSRDAVQAPASSSPQCSQPAAAQVPTHLLAKLLLLKHTAEEDHDFLENEQFFLETLKKAPYNMAYHSA" } }, { "url": "https://www.uniprot.org/uniprot/A2A870#A2A872-1", "isoform_ac": "A2A872-1", "locus": { "end_pos": 116164682, "strand": "+", "start_pos": 116165882, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000139020", "id": "ENSMUST00000139020", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000114893", "id": "ENSMUSP00000114893", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A2A872-1|FBF1_MOUSE Computationally mapped isoform of Fas-binding factor 1 OS=Mus musculus OX=10090 GN=Fbf1 PE=1 SV=8 CANONICAL=A2A870-1", "length": 20, "sequence": "MTGQCCEELQRAPKPRMALR" } }, { "url": "https://www.uniprot.org/uniprot/A2A870#Z4YLK3-1", "isoform_ac": "Z4YLK3-1", "locus": { "end_pos": 116155086, "strand": "+", "start_pos": 116165882, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000124828", "id": "ENSMUST00000124828", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000114558", "id": "ENSMUSP00000114558", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|Z4YLK3-1|FBF1_MOUSE Computationally mapped isoform of Fas-binding factor 1 OS=Mus musculus OX=10090 GN=Fbf1 PE=1 SV=1 CANONICAL=A2A870-1", "length": 227, "sequence": "MTGQCCEELQRAPKPRMALRTKKGLKGSIEDVLGDLLGDDTTPPEKPAEPASHAKDTASSPQWQASKAKFLPKDSVEGLAGADAEASSVSDADPQVFLQNMKDLDSMDDDLFGRMKSHQPSGKGAAKGPGKEGPSNHKPAGTLTANEKGYTMPTKKPPPSSSKTGLQYKKFSFEDFEDPLAGLLSDEEEETATKLPAVERKPAPKSPGAAAGQGPSVPLTPGDTPIR" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:217335", "resource": "KEGG Pathway", "id": "mmu:217335", "name": "" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5620912", "resource": "Reactome", "id": "R-MMU-5620912", "name": "Anchoring of the basal body to the plasma membrane" } ], "function": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766159.3", "annotation": "Albatross is a novel protein that spatiotemporally integrates different aspects of centrosome function, namely ciliogenesis, centriole duplication, and centrosome separation.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766159.3", "id": "NP_766159.3", "database": "RefSeq" } ] }, { "url": "https://www.uniprot.org/uniprot/A2A870#function", "annotation": "Keratin-binding protein required for epithelial cell polarization. Involved in apical junction complex (AJC) assembly via its interaction with PARD3. Required for ciliogenesis (By similarity).", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870#function", "id": "A2A870", "database": "UniProtKB" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766159.3", "annotation": "Keratins and the keratin-binding protein Albatross are important for epithelial cell polarization.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766159.3", "id": "NP_766159.3", "database": "RefSeq" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q8TES7-1", "protein_name": "Fas-binding factor 1", "sequence": { "length": 1133, "sequence": "MAPKTKKGCKVTLPEKPVKLASHTRDTTGVSQMFPSSKARTKSLLGDDVFSTMAGLEEADAEVSGISEADPQALLQAMKDLDGMDADILGLKKSNSAPSKKAAKDPGKGELPNHPKPAGGAIPTKKSLPSPSSSGHQNRRFSSEDLEDPLRGLLSYDEGGITKQPPVTQSKTASDKSPSTVRDQGPSIPLTPGDTPIRKKEELLFDDGDDIMATLGFGDSPKAEKRQIGDQEGPRPARSTLDELLGRGMATKLLARPGTGEHREFKLDKKYQRPQDSEDMWGDEDFTFGAYQPTVVSSEGRQSRRQSVSRFFADSGADPKGEPGSKQSPPMASSPIQPRKGGADWLGLKDEDLDLFPASPTREAHRESSVPVTPSVPPPASQHSTPAGLPPSRAKPPTEGAGSPAKASQASKLRASKEEKEDWLSHALSRKKSQGLAREQHAGTSEGLHLAGTAGHPPSGSQPLTSTQGLEHAAAGGSSGTTARERPCVRPGVSGSPVTQNHAASALPTGSPKRGTAPGDLSATEPATCFPSTQKPTEPSVPVQPLLPESLARSLLPSTEYQKQLLAAQVQLQCSPAELQAELLHSQARLAELEAQVRKLELERAQHELLLGSLQQQHQADLELIESAHRSRIKVLETSYQQREERLRRENEELSARYLSQCQEAEQARAELTAQHQRRLAAIAQEKDQEMERLRELQRASILDMRRDHEEQLQRLKLLKDREVDAATSATSHTRSLNSIIHQMEKFSSSLHELSSRVEASHLTTSQERELGIRQRDEQLRALQERLGQQQRDMEEERSRQQEVIGKMEARLNEQSRLLEQERWRVTAEQSKAESMQRALEEQRKVTAQQMAMERAELERAKSALLEEQKSVMLKCGEERRRLAAEWAEFSAQQKLSKERAEREAERALQVDTQREGTLISLAKQAELKIRASELRAEEKQLAAERAALEQERQELRLEKERINATALRVKLRAEEVESMSKVASEKYEEGERALREAQQVQAEQQARLQAVQQQQERLRKQEQHMHQEHLSLAQQRLQLDRARQDLPSSLVGLFPRAQGPAASSQSALMPPAPTTRWCSQPPTGLDPSPLHLHARLALLRHMAEQDRDFLENEQFFLETLKKGSYNLTSHSA" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/16531", "id": "16531", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "gene_name": "FBF1", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766159.3", "ac": "NP_766159.3", "name": "fas-binding factor 1 isoform 1", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "pmid": "24469809", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "name": "centriole", "id": "GO:0005814" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "name": "ciliary basal body", "id": "GO:0036064" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "name": "spindle pole", "id": "GO:0000922" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "name": "centrosome", "id": "GO:0005813" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045095", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "name": "keratin filament", "id": "GO:0045095" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097539", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "name": "ciliary transition fiber", "id": "GO:0097539" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "name": "apical junction complex", "id": "GO:0043296" } ], "total": 8, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043297", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "name": "apical junction assembly", "id": "GO:0043297" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "name": "cilium assembly", "id": "GO:0060271" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090162", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "name": "establishment of epithelial cell polarity", "id": "GO:0090162" } ], "total": 3, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A2A870", "type": "synonym", "resource": "RefSeq", "name": "1110033G01Rik; 5930413D20; mKIAA1863" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2A870", "type": "synonym", "resource": "RefSeq", "name": "Fbf1" }, { "url": "https://www.uniprot.org/uniprot/A2A870", "type": "recommended", "resource": "UniProtKB", "name": "Fbf1" } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000020776", "id": "ENSMUSG00000020776", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/217335", "id": "217335", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/intact/interactors/id:A2A870*", "id": "A2A870", "database": "IntAct" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR033561", "id": "IPR033561", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:217335", "id": "mmu:217335", "database": "KEGG Pathway" }, { "url": "http://www.informatics.jax.org/marker/MGI:1922033", "id": "1922033", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/QYRKFSF/", "id": "QYRKFSF", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=399859at2759", "id": "399859at2759", "database": "OrthoDB" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33689", "id": "PTHR33689", "database": "PANTHER" }, { "url": "http://purl.obolibrary.org/obo/PR_PR_A2A870", "id": "PR_A2A870", "database": "PRO" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-5620912", "id": "R-MMU-5620912", "database": "Reactome" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766159.3", "id": "NP_766159.3", "database": "RefSeq" }, { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [ { "residue": "Ser", "kinase_gene_name": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "id": "A2A870", "database": "UniProtKB" } ], "start_pos": "172", "end_pos": "172", "kinase_uniprot_canonical_ac": "" } ], "mass": { "monoisotopic_mass": 130138.0, "chemical_mass": 130138.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A2A870", "name": "Fbf1", "locus": { "end_pos": 116142285, "strand": "-", "start_pos": 116168166, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000020776", "id": "ENSMUSG00000020776", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A2A870#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "FBF-1" }, { "url": "https://www.uniprot.org/uniprot/A2A870#names_and_taxonomy", "type": "recommended", "resource": "UniProtKB", "name": "Fas-binding factor 1" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2A870", "type": "synonym", "resource": "RefSeq", "name": "fas-binding factor 1 isoform 1" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2A870", "type": "synonym", "resource": "RefSeq", "name": "fas-binding factor 1; likely ortholog of H. sapiens Fas (TNFRSF6) binding factor 1 (FBF1); FBF-1" } ] }