{ "uniprot_canonical_ac": "A1L157-1", "ptm_annotation": [], "sequence": { "header": "sp|A1L157-1|TSN11_HUMAN Isoform 1 of Tetraspanin-11 OS=Homo sapiens OX=9606 GN=TSPAN11 PE=2 SV=2 CANONICAL=A1L157-1", "length": 253, "sequence": "MAHYKTEQDDWLIIYLKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGVLVMVTGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAENYGQPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTVVVRCGQRAHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHQRLQRHFY" }, "uniprot_id": "TSN11_HUMAN", "enzyme_annotation": [], "glycation": [], "keywords": [ "glycoprotein", "predicted.uniprotkb_gly" ], "species": [ { "common_name": "Human", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1L157", "id": "A1L157", "database": "UniProtKB" } ], "name": "Homo sapiens", "taxid": 9606 } ], "publication": [], "uniprot_ac": "A1L157", "site_annotation": [ { "end_pos": 129, "annotation": "n_glycosylation_sequon", "start_pos": 127 }, { "end_pos": 161, "annotation": "n_glycosylation_sequon", "start_pos": 159 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A1L157#A1L157-1", "isoform_ac": "A1L157-1", "locus": { "end_pos": 30953992, "strand": "-", "start_pos": 30991912, "chromosome": "12", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000261177", "id": "ENST00000261177", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000261177", "id": "ENSP00000261177", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A1L157-1|TSN11_HUMAN Isoform 1 of Tetraspanin-11 OS=Homo sapiens OX=9606 GN=TSPAN11 PE=2 SV=2 CANONICAL=A1L157-1", "length": 253, "sequence": "MAHYKTEQDDWLIIYLKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGVLVMVTGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAENYGQPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTVVVRCGQRAHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHQRLQRHFY" } }, { "url": "https://www.uniprot.org/uniprot/A1L157#F5H195-1", "isoform_ac": "F5H195-1", "locus": { "end_pos": 30953992, "strand": "-", "start_pos": 30954114, "chromosome": "12", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000545802", "id": "ENST00000545802", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000443890", "id": "ENSP00000443890", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F5H195-1|TSN11_HUMAN Computationally mapped isoform of Tetraspanin-11 OS=Homo sapiens OX=9606 GN=TSPAN11 PE=2 SV=1 CANONICAL=A1L157-1", "length": 41, "sequence": "MAHYKTEQDDWLIIYLKYLLFVFNFFFWVSEFCTHILFPEH" } }, { "url": "https://www.uniprot.org/uniprot/A1L157#F5H2P0-1", "isoform_ac": "F5H2P0-1", "locus": { "end_pos": 30963955, "strand": "-", "start_pos": 30991912, "chromosome": "12", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000535215", "id": "ENST00000535215", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000445503", "id": "ENSP00000445503", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F5H2P0-1|TSN11_HUMAN Computationally mapped isoform of Tetraspanin-11 OS=Homo sapiens OX=9606 GN=TSPAN11 PE=2 SV=1 CANONICAL=A1L157-1", "length": 182, "sequence": "MVTGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAENYGQPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDSCCKTVVVRCGQRAHPSNIYKVEGGCLTKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHQRLQRHFY" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:441631", "resource": "KEGG Pathway", "id": "hsa:441631", "name": "" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "Q568Y5-1", "protein_name": "Tetraspanin-11", "sequence": { "length": 253, "sequence": "MAHCKTEQDDWLLAHLKYLLFIFNFFFWVGGAAVMAVGIWTLVEKSVYLSILASSTFAASAYVLIFVGGLVMTTGFLGFGAIIREQKSCLSTYFCLLLAIFLVELVAGVLAHVYYQRLSDELKRHLHSTLTEHYGQPGAAEITASVDRLQQDFKCCGSNSSADWQHSVYILSQEAIGRQVPDSCCKTVVARCGQRAHPSNIYKVEGGCMAKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHRRLQQHFY" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/23595", "id": "23595", "database": "MGI" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "gene_name": "Tspan11", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q9D1D1-1", "protein_name": "Tetraspanin-11", "sequence": { "length": 253, "sequence": "MAHCKTEQDDWLLAHLKYLLFIFNFFFWVGGAAVMAVGIWTLVEKSGYLSILASSTFAASAYILIFVGGLVMTTGFLGFGAIIREQKSCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKWHLNSTLTEHYGQPRAAEITASVDRLQQDFKCCGSNSSADWQHSAYILSQEALGRQVPDSCCKTVVARCGQRAHPSNIYKVEGGCMAKLEQFVADHLLLMGAVGIGVACLQICGMVLTCCLHRRLQQQFY" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/23595", "id": "23595", "database": "MGI" } ], "common_name": "Mouse", "organism": "Mus musculus", "gene_name": "Tspan11", "tax_id": 10090 } ], "interactions": [], "synthesized_glycans": [], "snv": [ { "sequence_org": "V", "start_pos": 106, "alt_nt": "A", "chr_id": "12", "ref_nt": "T", "chr_pos": "31131536", "disease": [ { "synonyms": [ { "id": "DOID:1781", "url": 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