{ "uniprot_canonical_ac": "A1A5Q5-1", "ptm_annotation": [], "sequence": { "header": "sp|A1A5Q5-1|KDM4D_RAT Isoform 1 of Lysine-specific demethylase 4D OS=Rattus norvegicus OX=10116 GN=Kdm4d PE=2 SV=1 CANONICAL=A1A5Q5-1", "length": 510, "sequence": "MKTKSTCAQNPNCSIMIFRPTKEEFNDFDKYIAYMESQGAHRAGLAKVIPPKEWRARQSYDNISNILIATPLQQVVSGQAGVFTQYHKKKKAMTVGQYRHLANSKKYQTPPHLDFEDLERKYWKNRLYESPIYGADVSGSLFDGKTQQWNVGHLGTIQDLLEQECGIVIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGQPKTWYAVPPEHGRRLELLAKELFPGSSQGCQAFLRHKVALISPTVLKENGIPFGRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEARVSFSMDAFVRILQPERYEMWKRGQDQAVVDHTEAMGPTSQELTTWRVIQAPRKTWGLKHLRLRQVSRCLLPVATDSNIANNTQMCHTSRQAADSKGDEVQESDPAIAPPYPLGLSSPGHMSTGKRGLGRRPCELGVQESTNGAPVKRRLPEGRDDRSPSPELQSQSVTGDLIVNSDLVNPGPQHPVTASEGGLTSDP" }, "uniprot_id": "KDM4D_RAT", "enzyme_annotation": [ { "ec": "1.14.11.66", "activity": "" }, { "ec": "1.14.11.66", "activity": "A [histone H3]-N(6),N(6),N(6)-trimethyl-L-lysine(9) + 2 2-oxoglutarate + 2 O(2) = a [histone H3]-N(6)-methyl-L-lysine(9) + 2 succinate + 2 formaldehyde + 2 CO(2)." } ], "glycation": [], "keywords": [], "species": [ { "common_name": "Rat", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/16738407", "type": [ "PubMed" ], "id": "16738407" } ], "title": "Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.", "journal": "Genes & development", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073180.1", "id": "NP_001073180.1", "database": "RefSeq" } ], "authors": "Fodor BD, Kubicek S, Yonezawa M, O'Sullivan RJ, Sengupta R, Perez-Burgos L, Opravil S, Mechtler K, Schotta G, Jenuwein T", "date": "2006" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/21293030", "type": [ "PubMed" ], "id": "21293030" } ], "title": "The testis-enriched histone demethylase, KDM4D, regulates methylation of histone H3 lysine 9 during spermatogenesis in the mouse but is dispensable for fertility.", "journal": "Biology of reproduction", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073180.1", "id": "NP_001073180.1", "database": "RefSeq" } ], "authors": "Iwamori N, Zhao M, Meistrich ML, Matzuk MM", "date": "2011" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/21914792", "type": [ "PubMed" ], "id": "21914792" } ], "title": "Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family.", "journal": "The Journal of biological chemistry", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073180.1", "id": "NP_001073180.1", "database": "RefSeq" } ], "authors": "Hillringhaus L, Yue WW, Rose NR, Ng SS, Gileadi C, Loenarz C, Bello SH, Bray JE, Schofield CJ, Oppermann U", "date": "2011" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/22516433", "type": [ "PubMed" ], "id": "22516433" } ], "title": "Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.", "journal": "Journal of proteomics", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073180.1", "id": "NP_001073180.1", "database": "RefSeq" } ], "authors": "Bastos-Amador P, Royo F, Gonzalez E, Conde-Vancells J, Palomo-Diez L, Borras FE, Falcon-Perez JM", "date": "2012" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/24219278", "type": [ "PubMed" ], "id": "24219278" } ], "title": "The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression.", "journal": "Biochemistry and cell biology = Biochimie et biologie cellulaire", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073180.1", "id": "NP_001073180.1", "database": "RefSeq" } ], "authors": "Young LC, Hendzel MJ", "date": "2013" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/24550317", "type": [ "PubMed" ], "id": "24550317" } ], "title": "PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073180.1", "id": "NP_001073180.1", "database": "RefSeq" } ], "authors": "Khoury-Haddad H, Guttmann-Raviv N, Ipenberg I, Huggins D, Jeyasekharan AD, Ayoub N", "date": "2014" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/25124442", "type": [ "PubMed" ], "id": "25124442" } ], "title": "Transdifferentiation. Sequential histone-modifying activities determine the robustness of transdifferentiation.", "journal": "Science (New York, N.Y.)", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073180.1", "id": "NP_001073180.1", "database": "RefSeq" } ], "authors": "Zuryn S, Ahier A, Portoso M, White ER, Morin MC, Margueron R, Jarriault S", "date": "2014" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/6953429", "type": [ "PubMed" ], "id": "6953429" } ], "title": "Isolation and characterization of rat skeletal muscle and cytoplasmic actin genes.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073180.1", "id": "NP_001073180.1", "database": "RefSeq" } ], "authors": "Nudel U, Katcoff D, Zakut R, Shani M, Carmon Y, Finer M, Czosnek H, Ginsburg I, Yaffe D", "date": "1982" } ], "uniprot_ac": "A1A5Q5", "site_annotation": [ { "end_pos": 14, "annotation": "n_glycosylation_sequon", "start_pos": 12 }, { "end_pos": 395, "annotation": "n_glycosylation_sequon", "start_pos": 393 }, { "end_pos": 64, "annotation": "n_glycosylation_sequon", "start_pos": 62 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5#A1A5Q5-1", "isoform_ac": "A1A5Q5-1", "locus": { "end_pos": 12968648, "strand": "+", "start_pos": 12970177, "chromosome": "8", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000033932", "id": "ENSRNOT00000033932", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000059913", "id": "ENSRNOP00000059913", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A1A5Q5-1|KDM4D_RAT Isoform 1 of Lysine-specific demethylase 4D OS=Rattus norvegicus OX=10116 GN=Kdm4d PE=2 SV=1 CANONICAL=A1A5Q5-1", "length": 510, "sequence": "MKTKSTCAQNPNCSIMIFRPTKEEFNDFDKYIAYMESQGAHRAGLAKVIPPKEWRARQSYDNISNILIATPLQQVVSGQAGVFTQYHKKKKAMTVGQYRHLANSKKYQTPPHLDFEDLERKYWKNRLYESPIYGADVSGSLFDGKTQQWNVGHLGTIQDLLEQECGIVIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGQPKTWYAVPPEHGRRLELLAKELFPGSSQGCQAFLRHKVALISPTVLKENGIPFGRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEARVSFSMDAFVRILQPERYEMWKRGQDQAVVDHTEAMGPTSQELTTWRVIQAPRKTWGLKHLRLRQVSRCLLPVATDSNIANNTQMCHTSRQAADSKGDEVQESDPAIAPPYPLGLSSPGHMSTGKRGLGRRPCELGVQESTNGAPVKRRLPEGRDDRSPSPELQSQSVTGDLIVNSDLVNPGPQHPVTASEGGLTSDP" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:108348070", "resource": "KEGG Pathway", "id": "rno:108348070", "name": "" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:689582", "resource": "KEGG Pathway", "id": "rno:689582", "name": "" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-3214842", "resource": "Reactome", "id": "R-RNO-3214842", "name": "HDMs demethylate histones" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5#function", "annotation": "Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5#function", "id": "A1A5Q5", "database": "UniProtKB" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q3U2K5-1", "protein_name": "Lysine-specific demethylase 4D", "sequence": { "length": 510, "sequence": "MKTKSTCAQNPNCSIMIFRPTKEEFNDFDKYIAYMESQGAHRAGLAKVIPPKEWRARQSYDNISNILIATPLQQVVSGQAGVFTQYHKKKKGMTVGEYRELANSKKYQTPPHLDFEDLERKYWKNRLYESPIYGADVSGSLFDGKTQQWNVGHLGTIQDLLEQECGIVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHFGQPKTWYAVPPEHGRRLERLARELFPGSSQGCQAFLRHKVALISPTVLKENGIPFGRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKVASQCSCGEARVSFSMDAFVRILQPERYELWKRGQDQAVVDHTETMVSTSQELTTRRVTKAPRKTWGLKRLRLRQVSRSLLPIATVSNVPCNMQVCHTSRQPSDVKGDDVQKSDSARASPHPLSLPSSGHMSTRRCSLGRRPCELGAQESSNGAPVKRQLPAGRDDTSPSPELQPQAVSGDLIVDSGLVNPGPQHLMTASEGGLTSDP" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/69244", "id": "69244", "database": "MGI" } ], "common_name": "Mouse", "organism": "Mus musculus", "gene_name": "Kdm4d", "tax_id": 10090 }, { "uniprot_canonical_ac": "Q6B0I6-1", "protein_name": "Lysine-specific demethylase 4D", "sequence": { "length": 523, "sequence": "METMKSKANCAQNPNCNIMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIATPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYGADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSINYLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPERYDLWKRGQDRAVVDHMEPRVPASQELSTQKEVQLPRRAALGLRQLPSHWARHSPWPMAARSGTRCHTLVCSSLPRRSAVSGTATQPRAAAVHSSKKPSSTPSSTPGPSAQIIHPSNGRRGRGRPPQKLRAQELTLQTPAKRPLLAGTTCTASGPEPEPLPEDGALMDKPVPLSPGLQHPVKASGCSWAPVP" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/69244", "id": "69244", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "gene_name": "KDM4D", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073180.1", "ac": "NP_001073180.1", "name": "lysine-specific demethylase 4D", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "metal ion binding", "id": "GO:0046872" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003684", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "damaged DNA binding", "id": "GO:0003684" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "chromatin DNA binding", "id": "GO:0031490" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051213", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "dioxygenase activity", "id": "GO:0051213" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032452", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "histone demethylase activity", "id": "GO:0032452" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032454", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "histone demethylase activity (H3-K9 specific)", "id": "GO:0032454" } ], "total": 6, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035097", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "histone methyltransferase complex", "id": "GO:0035097" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "nucleus", "id": "GO:0005634" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035861", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "site of double-strand break", "id": "GO:0035861" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005721", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "pericentric heterochromatin", "id": "GO:0005721" } ], "total": 4, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "chromatin remodeling", "id": "GO:0006338" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035563", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "positive regulation of chromatin binding", "id": "GO:0035563" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001034", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "positive regulation of double-strand break repair via nonhomologous end joining", "id": "GO:2001034" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900113", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "negative regulation of histone H3-K9 trimethylation", "id": "GO:1900113" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "cellular response to DNA damage stimulus", "id": "GO:0006974" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "double-strand break repair via homologous recombination", "id": "GO:0000724" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001932", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "regulation of protein phosphorylation", "id": "GO:0001932" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071479", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "cellular response to ionizing radiation", "id": "GO:0071479" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033169", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "name": "histone H3-K9 demethylation", "id": "GO:0033169" } ], "total": 9, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "type": "synonym", "resource": "UniProtKB", "name": "Jhdm3d" }, { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "type": "synonym", "resource": "UniProtKB", "name": "Jmjd2d" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A1A5Q5", "type": "synonym", "resource": "RefSeq", "name": "Kdm4d" }, { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "type": "recommended", "resource": "UniProtKB", "name": "Kdm4d" } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000024726", "id": "ENSRNOG00000024726", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/108348070", "id": "108348070", "database": "GeneID" }, { "url": 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"database": "PRO" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-3214842", "id": "R-RNO-3214842", "database": "Reactome" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073180.1", "id": "NP_001073180.1", "database": "RefSeq" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1591045", "id": "1591045", "database": "RGD" }, { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "id": "A1A5Q5", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [ { "synonyms": [ { "id": "MONDO:0008679", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "resource": "MONDO", "name": "Wilms tumor type 1", "description": "" }, { "id": "MONDO:0008679", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "resource": "MONDO", "name": "Wilms tumor 1; WT1", "description": "" }, { "id": "MONDO:0008679", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "resource": "MONDO", "name": "WT1", "description": "" }, { "id": "MONDO:0008679", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "resource": "MONDO", "name": "Wilms tumor 1", "description": "" }, { "id": "MONDO:0008679", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "resource": "MONDO", "name": "renal Wilms tumor", "description": "" }, { "id": "MONDO:0008679", "url": "https://monarchinitiative.org/disease/MONDO:0008679", "resource": "MONDO", "name": "Wilms' tumor", "description": "" }, { "id": "DOID:2154", "url": "http://disease-ontology.org/term/DOID:2154", "resource": "Disease Ontology", "name": "adult nephroblastoma", "description": "" } ], "recommended_name": { "id": "DOID:2154", "url": "http://disease-ontology.org/term/DOID:2154", "resource": "Disease Ontology", "name": "nephroblastoma", "description": "A kidney cancer that affects the kidneys and typically located_in children." }, "evidence": [ { "url": "https://www.alliancegenome.org/gene/2154#disease-associations", "id": "2154", "database": "Alliance of Genome Resources" } ] } ], "phosphorylation": [], "mass": { "monoisotopic_mass": 57188.0, "chemical_mass": 57188.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5", "name": "Kdm4d", "locus": { "end_pos": 13511805, "strand": "-", "start_pos": 13513337, "chromosome": "8", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000045905", "id": "ENSRNOG00000045905", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A1A5Q5#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "1.14.11.66" }, { "url": "https://www.uniprot.org/uniprot/A1A5Q5#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "JmjC domain-containing histone demethylation protein 3D" }, { "url": "https://www.uniprot.org/uniprot/A1A5Q5#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "Jumonji domain-containing protein 2D" }, { "url": "https://www.uniprot.org/uniprot/A1A5Q5#names_and_taxonomy", "type": "recommended", "resource": "UniProtKB", "name": "Lysine-specific demethylase 4D" }, { "url": "https://www.uniprot.org/uniprot/A1A5Q5#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "[histone H3]-trimethyl-L-lysine(9) demethylase 4D" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A1A5Q5", "type": "synonym", "resource": "RefSeq", "name": "jumonji domain-containing protein 2D; jmjC domain-containing histone demethylation protein 3D; lysine (K)-specific demethylase 4D; [histone H3]-trimethyl-L-lysine(9) demethylase 4D" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A1A5Q5", "type": "synonym", "resource": "RefSeq", "name": "lysine-specific demethylase 4D" } ] }