{
    "uniprot_canonical_ac": "A1A5D9-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A1A5D9-1|BICL2_HUMAN Isoform 1 of BICD family-like cargo adapter 2  OS=Homo sapiens OX=9606 GN=BICDL2 PE=1 SV=2 CANONICAL=A1A5D9-1", 
        "length": 508, 
        "sequence": "MSSPDGPSFPSGPLSGGASPSGDEGFFPFVLERRDSFLGGGPGPEEPEDLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLSAQHLEREERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSEQQDSGRERARALSELSEQNLRLSQQLAQASQTEQELQRELDALRGQCQAQALAGAELRTRLESLQGENQMLQSRRQDLEAQIRGLREEVEKGEGRLQTTHEELLLLRRERREHSLELERARSEAGEALSALRRLQRRVSELEEESRLQDADVSAASLQSELAHSLDDGDQGQGADAPGDTPTTRSPKTRKASSPQPSPPEEILEPPKKRTSLSPAEILEEKEVEVAKLQDEISLQQAELQSLREELQRQKELRAQEDPGEALHSALSDRDEAVNKALELSLQLNRVSLERDSLSRELLRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSASASSSTPRRAAPRFSLRLGPGPAGGFLSNLFRRT"
    }, 
    "uniprot_id": "BICL2_HUMAN", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [
        "glycoprotein", 
        "reported_with_glycan.oglcnac_db"
    ], 
    "species": [
        {
            "common_name": "Human", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/28411811", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "28411811"
                }
            ], 
            "title": "A novel strategy for global mapping of O-GlcNAc proteins and peptides using selective enzymatic deglycosylation, HILIC enrichment and mass spectrometry identification.", 
            "journal": "Talanta", 
            "evidence": [
                {
                    "url": "https://data.glygen.org/GLYDS000517", 
                    "id": "GLYDS000517", 
                    "database": "GlyGen"
                }
            ], 
            "authors": "Shen B, Zhang W, Shi Z, Tian F, Deng Y, Sun C, Wang G, Qin W, Qian X", 
            "date": "2017"
        }
    ], 
    "uniprot_ac": "A1A5D9", 
    "site_annotation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A1A5D9#A0A2R8Y2X6-1", 
            "isoform_ac": "A0A2R8Y2X6-1", 
            "locus": {
                "end_pos": 3028109, 
                "strand": "+", 
                "start_pos": 3035496, 
                "chromosome": "16", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000642419", 
                        "id": "ENST00000642419", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000493502", 
                        "id": "ENSP00000493502", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A2R8Y2X6-1|BICL2_HUMAN Computationally mapped isoform of BICD family-like cargo adapter 2  OS=Homo sapiens OX=9606 GN=BICDL2 PE=1 SV=1 CANONICAL=A1A5D9-1", 
                "length": 541, 
                "sequence": "MSSPDGPSFPSGPLSGGASPSGDEGFFPFVLERRDSFLGGGPGPEEPEDLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLSAQHLEREEVCAAMGRGLNSARLRRQKRRLRPQVQKPRQQLERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSEQQDSGRERARALSELSEQNLRLSQQLAQASQTEQELQRELDALRGQCQAQALAGAELRTRLESLQGENQMLQSRRQDLEAQIRGLREEVEKGEGRLQTTHEELLLLRRERREHSLELERARSEAGEALSALRRLQRRVSELEEESRLQDADVSAASLQSELAHSLDDGDQGQGADAPGDTPTTRSPKTRKASSPQPSPPEEILEPPKKRTSLSPAEILEEKEVEVAKLQDEISLQQAELQSLREELQRQKELRAQEDPGEALHSALSDRDEAVNKALELSLQLNRVSLERDSLSRELLRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSASASSSTPRRAAPRFSLRLGPGPAGGFLSNLFRRT"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1A5D9#A1A5D9-1", 
            "isoform_ac": "A1A5D9-1", 
            "locus": {
                "end_pos": 3028109, 
                "strand": "+", 
                "start_pos": 3035496, 
                "chromosome": "16", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000389347", 
                        "id": "ENST00000389347", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000373998", 
                        "id": "ENSP00000373998", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A1A5D9-1|BICL2_HUMAN Isoform 1 of BICD family-like cargo adapter 2  OS=Homo sapiens OX=9606 GN=BICDL2 PE=1 SV=2 CANONICAL=A1A5D9-1", 
                "length": 508, 
                "sequence": "MSSPDGPSFPSGPLSGGASPSGDEGFFPFVLERRDSFLGGGPGPEEPEDLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLSAQHLEREERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSEQQDSGRERARALSELSEQNLRLSQQLAQASQTEQELQRELDALRGQCQAQALAGAELRTRLESLQGENQMLQSRRQDLEAQIRGLREEVEKGEGRLQTTHEELLLLRRERREHSLELERARSEAGEALSALRRLQRRVSELEEESRLQDADVSAASLQSELAHSLDDGDQGQGADAPGDTPTTRSPKTRKASSPQPSPPEEILEPPKKRTSLSPAEILEEKEVEVAKLQDEISLQQAELQSLREELQRQKELRAQEDPGEALHSALSDRDEAVNKALELSLQLNRVSLERDSLSRELLRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSASASSSTPRRAAPRFSLRLGPGPAGGFLSNLFRRT"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1A5D9#A1A5D9-2", 
            "isoform_ac": "A1A5D9-2", 
            "locus": {
                "end_pos": 3028109, 
                "strand": "+", 
                "start_pos": 3030589, 
                "chromosome": "16", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000573514", 
                        "id": "ENST00000573514", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000461724", 
                        "id": "ENSP00000461724", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A1A5D9-2|BICL2_HUMAN Isoform 2 of BICD family-like cargo adapter 2  OS=Homo sapiens OX=9606 GN=BICDL2 PE=1 SV=2 CANONICAL=A1A5D9-1", 
                "length": 301, 
                "sequence": "MLQSRRQDLEAQIRGLREEVEKGEGRLQTTHEELLLLRRERREHSLELERARSEAGEALSALRRLQRRVSELEEESRLQDADVSAASLQSELAHSLDDGDQGQGADAPGDTPTTRSPKTRKASSPQPSPPEEILEPPKKRTSLSPAEILEEKEVEVAKLQDEISLQQAELQSLREELQRQKELRAQEDPGEALHSALSDRDEAVNKALELSLQLNRVSLERDSLSRELLRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSASASSSTPRRAAPRFSLRLGPGPAGGFLSNLFRRT"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:146439", 
            "resource": "KEGG Pathway", 
            "id": "hsa:146439", 
            "name": ""
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "B1WBT3-1", 
            "protein_name": "Uncharacterized protein RGD1306729_predicted", 
            "sequence": {
                "length": 507, 
                "sequence": "MDSPGGPSFSSGLLSGGASPSGDEGFFPFVLERRDSFLGGGPGPEEPEDLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNAQHLEHEERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSEQQDSGRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRGQCQTQALAGAELRTRLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQGRLQTTHEELLLLRRERKEHKLELERARFEAGEALSTLRRLQRRVSELEEESRLQDAEISGASLQTELAHSLDSDQDQDQQVNECRASQTILSPETEEASSPQPSIQEESLEPPKKRASLSPVEILEEKEAEVARLQDEISLHRTELQSLRDELQRQKELRAQDNPEEALSCALSDRDEAVNKALKLSLELNRVSLERDSLSRELMRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSEAAAAPRRSKTRFSLRLGSGQSGGFLSNFFRRT"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/17815", 
                    "id": "17815", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Rat", 
            "organism": "Rattus norvegicus", 
            "gene_name": "Bicdl2", 
            "tax_id": 10116
        }, 
        {
            "uniprot_canonical_ac": "Q8CHW5-1", 
            "protein_name": "BICD family-like cargo adapter 2", 
            "sequence": {
                "length": 507, 
                "sequence": "MDSPGEPSFPSGLLSGGASPSGDEGFFPFVLERRDSFLGGGPGPEEPEDLALQLQQKEKDLLLAAELGKMLLERNEELRRQLETLNTQHLEHEERLQQENHELRRGLAARGAEWEARAVELEGDVEALRAQLGEQRSERQDSGRERARALGELSEQNLRLSQQLAQASRTEQELQRELDTLRERCQTQALAGAELGARLESLQAENQMLQDRRQDLEAQIRGLREEVDKGQNRLQTTHEELLLLRRERKEHKLELERARFEAGEALRTLRGLQRRVSELEEESRLQDTEISGASLQTELAHSLDSDQDQDQQVNECGGSQAILSPETQETSSPQPSIQEEILEPPKKRASLSPVEILEEKEAEVARLQDEITLHRTELQTLRDELQRQKELRAQDNPEEALSSALSDRDEAVNKAMKLSLELSRVSLERDSLSRELLRAIRQKVALTQELEAWQDDMQVVIGQQLRSQRQKELSEAAAAPRRAKTRFSLRLGSGQSGGFLSNLFRRT"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/17815", 
                    "id": "17815", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "gene_name": "Bicdl2", 
            "tax_id": 10090
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [
        {
            "sequence_org": "A", 
            "start_pos": 118, 
            "alt_nt": "A", 
            "chr_id": "16", 
            "ref_nt": "G", 
            "chr_pos": "3081081", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "Thyroid gland neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumour of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "thyroid neoplasm", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:1781", 
                        "url": "http://disease-ontology.org/term/DOID:1781", 
                        "resource": "Disease Ontology", 
                        "name": "thyroid gland cancer", 
                        "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "2.0", 
            "sequence_mut": "V", 
            "subjects_tested": "50", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%).", 
            "end_pos": 118, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "E", 
            "start_pos": 171, 
            "alt_nt": "G", 
            "chr_id": "16", 
            "ref_nt": "C", 
            "chr_pos": "3080801", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:11934", 
                            "url": "http://disease-ontology.org/term/DOID:11934", 
                            "resource": "Disease Ontology", 
                            "name": "head and neck neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:11934", 
                            "url": "http://disease-ontology.org/term/DOID:11934", 
                            "resource": "Disease Ontology", 
                            "name": "head and neck tumours", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:11934", 
                            "url": "http://disease-ontology.org/term/DOID:11934", 
                            "resource": "Disease Ontology", 
                            "name": "head/neck neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:11934", 
                            "url": "http://disease-ontology.org/term/DOID:11934", 
                            "resource": "Disease Ontology", 
                            "name": "tumor of head and neck", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:11934", 
                        "url": "http://disease-ontology.org/term/DOID:11934", 
                        "resource": "Disease Ontology", 
                        "name": "head and neck cancer", 
                        "description": "An organ system cancer that arises in the head or neck region. This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "2.3", 
            "sequence_mut": "Q", 
            "subjects_tested": "44", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.3%).", 
            "end_pos": 171, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "Q", 
            "start_pos": 273, 
            "alt_nt": "T", 
            "chr_id": "16", 
            "ref_nt": "G", 
            "chr_pos": "3079686", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "Thyroid gland neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumour of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "thyroid neoplasm", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:1781", 
                        "url": "http://disease-ontology.org/term/DOID:1781", 
                        "resource": "Disease Ontology", 
                        "name": "thyroid gland cancer", 
                        "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "2.0", 
            "sequence_mut": "K", 
            "subjects_tested": "50", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%).", 
            "end_pos": 273, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "D", 
            "start_pos": 317, 
            "alt_nt": "T", 
            "chr_id": "16", 
            "ref_nt": "G", 
            "chr_pos": "3079552", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "Thyroid gland neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumour of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "thyroid neoplasm", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:1781", 
                        "url": "http://disease-ontology.org/term/DOID:1781", 
                        "resource": "Disease Ontology", 
                        "name": "thyroid gland cancer", 
                        "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "2.0", 
            "sequence_mut": "E", 
            "subjects_tested": "50", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%).", 
            "end_pos": 317, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "E", 
            "start_pos": 32, 
            "alt_nt": "T", 
            "chr_id": "16", 
            "ref_nt": "C", 
            "chr_pos": "3085404", 
            "disease": [
                {
                    "synonyms": [], 
                    "recommended_name": {
                        "id": "DOID:1324", 
                        "url": "http://disease-ontology.org/term/DOID:1324", 
                        "resource": "Disease Ontology", 
                        "name": "lung cancer", 
                        "description": "A respiratory system cancer that is located_in the lung."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "1.5", 
            "sequence_mut": "K", 
            "subjects_tested": "66", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (1.5%).", 
            "end_pos": 32, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "R", 
            "start_pos": 437, 
            "alt_nt": "T", 
            "chr_id": "16", 
            "ref_nt": "C", 
            "chr_pos": "3078398", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "Thyroid gland neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumour of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "thyroid neoplasm", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:1781", 
                        "url": "http://disease-ontology.org/term/DOID:1781", 
                        "resource": "Disease Ontology", 
                        "name": "thyroid gland cancer", 
                        "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "2.0", 
            "sequence_mut": "H", 
            "subjects_tested": "50", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%).", 
            "end_pos": 437, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "L", 
            "start_pos": 82, 
            "alt_nt": "G", 
            "chr_id": "16", 
            "ref_nt": "A", 
            "chr_pos": "3085253", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "Thyroid gland neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumour of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "thyroid neoplasm", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:1781", 
                        "url": "http://disease-ontology.org/term/DOID:1781", 
                        "resource": "Disease Ontology", 
                        "name": "thyroid gland cancer", 
                        "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "2.0", 
            "sequence_mut": "P", 
            "subjects_tested": "50", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.0%).", 
            "end_pos": 82, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }
    ], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096645.1", 
        "ac": "NP_001096645.1", 
        "name": "BICD family-like cargo adapter 2", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017137", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5D9", 
                                "id": "A1A5D9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "Rab GTPase binding", 
                        "id": "GO:0017137"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5D9", 
                                "id": "A1A5D9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047496", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5D9", 
                                "id": "A1A5D9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "vesicle transport along microtubule", 
                        "id": "GO:0047496"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055107", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1A5D9", 
                                "id": "A1A5D9", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "Golgi to secretory granule transport", 
                        "id": "GO:0055107"
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1A5D9", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "BICDL2"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1A5D9", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "BICDL2"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1A5D9", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "BICDR-2; BICDR2; CCDC64B"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1A5D9", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "BICDR2"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1A5D9", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "CCDC64B"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
            "id": "ENSG00000162069", 
            "database": "Bgee"
        }, 
        {
            "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A1A5D9", 
            "id": "A1A5D9", 
            "database": "BioMuta"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=BICDL2", 
            "id": "BICDL2", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/146439", 
            "id": "146439", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=33584", 
            "id": "33584", 
            "database": "HGNC"
        }, 
        {
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A1A5D9*", 
            "id": "A1A5D9", 
            "database": "IntAct"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:146439", 
            "id": "hsa:146439", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.omim.org/entry/617003", 
            "id": "617003", 
            "database": "MIM"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A1A5D9", 
            "id": "NX_A1A5D9", 
            "database": "neXtProt"
        }, 
        {
            "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A1A5D9", 
            "id": "A1A5D9", 
            "database": "O-GlcNAc Database"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/EMLSAQH/", 
            "id": "EMLSAQH", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=595515at2759", 
            "id": "595515at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "https://pharos.nih.gov/targets/A1A5D9", 
            "id": "A1A5D9", 
            "database": "PHAROS"
        }, 
        {
            "url": "http://purl.obolibrary.org/obo/PR_PR_A1A5D9", 
            "id": "PR_A1A5D9", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096645.1", 
            "id": "NP_001096645.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1A5D9", 
            "id": "A1A5D9", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [
        {
            "name": "Prostate cancer [DO disease name]", 
            "trend": "Up", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "NGP - new growth of prostate", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "hereditary prostate cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of the prostate", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "prostate cancer, familial", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "prostate neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "prostatic cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "prostatic neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10283", 
                            "url": "http://disease-ontology.org/term/DOID:10283", 
                            "resource": "Disease Ontology", 
                            "name": "tumor of the prostate", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:10283", 
                        "url": "http://disease-ontology.org/term/DOID:10283", 
                        "resource": "Disease Ontology", 
                        "name": "prostate cancer", 
                        "description": "A male reproductive organ cancer that is located_in the prostate."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:10283", 
            "significant": "No"
        }, 
        {
            "name": "Urinary bladder cancer [DO disease name]", 
            "trend": "Up", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:11054", 
                            "url": "http://disease-ontology.org/term/DOID:11054", 
                            "resource": "Disease Ontology", 
                            "name": "bladder cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:11054", 
                            "url": "http://disease-ontology.org/term/DOID:11054", 
                            "resource": "Disease Ontology", 
                            "name": "tumor of the bladder", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:11054", 
                        "url": "http://disease-ontology.org/term/DOID:11054", 
                        "resource": "Disease Ontology", 
                        "name": "urinary bladder cancer", 
                        "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:11054", 
            "significant": "No"
        }, 
        {
            "name": "Thyroid gland cancer [DO disease name]", 
            "trend": "Up", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "Thyroid gland neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumour of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "thyroid neoplasm", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:1781", 
                        "url": "http://disease-ontology.org/term/DOID:1781", 
                        "resource": "Disease Ontology", 
                        "name": "thyroid gland cancer", 
                        "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:1781", 
            "significant": "Yes"
        }, 
        {
            "name": "Liver cancer [DO disease name]", 
            "trend": "Down", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "Ca liver - primary", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "Resectable malignant neoplasm of Liver", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "hepatic cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "hepatic neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "malignant hepato-biliary neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of liver", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of liver, primary", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of liver", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "neoplasm of liver", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "non-resectable primary hepatic malignant neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "primary liver cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "primary malignant neoplasm of Liver", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "resectable malignant neoplasm of the liver", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3571", 
                            "url": "http://disease-ontology.org/term/DOID:3571", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of liver, not specified as primary or secondary", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:3571", 
                        "url": "http://disease-ontology.org/term/DOID:3571", 
                        "resource": "Disease Ontology", 
                        "name": "liver cancer", 
                        "description": "A hepatobiliary system cancer that is located_in the liver."
                    }
                }
            ], 
            "evidence": [
                {
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                    "id": "A1A5D9", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:3571", 
            "significant": "No"
        }, 
        {
            "name": "Lung squamous cell carcinoma [DO disease name]", 
            "trend": "Down", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:3907", 
                            "url": "http://disease-ontology.org/term/DOID:3907", 
                            "resource": "Disease Ontology", 
                            "name": "Epidermoid cell carcinoma of the lung", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:3907", 
                        "url": "http://disease-ontology.org/term/DOID:3907", 
                        "resource": "Disease Ontology", 
                        "name": "lung squamous cell carcinoma", 
                        "description": "A non-small cell lung carcinoma that has_material_basis_in the squamous cell."
                    }
                }
            ], 
            "evidence": [
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                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:3907", 
            "significant": "No"
        }, 
        {
            "name": "Lung adenocarcinoma [DO disease name]", 
            "trend": "Down", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:3910", 
                            "url": "http://disease-ontology.org/term/DOID:3910", 
                            "resource": "Disease Ontology", 
                            "name": "bronchogenic lung adenocarcinoma", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:3910", 
                            "url": "http://disease-ontology.org/term/DOID:3910", 
                            "resource": "Disease Ontology", 
                            "name": "nonsmall cell adenocarcinoma", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:3910", 
                        "url": "http://disease-ontology.org/term/DOID:3910", 
                        "resource": "Disease Ontology", 
                        "name": "lung adenocarcinoma", 
                        "description": "A lung cancer that derives_from epithelial cells of glandular origin."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:3910", 
            "significant": "No"
        }, 
        {
            "name": "Esophageal cancer [DO disease name]", 
            "trend": "Down", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "Ca lower third oesophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "Ca middle third oesophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "esophagus cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of distal third of esophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of lower third of oesophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of middle third of oesophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of proximal third of esophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of upper third esophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of Distal Third of esophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of Proximal Third of esophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of abdominal esophagus", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:5041", 
                            "url": "http://disease-ontology.org/term/DOID:5041", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumor of the middle Third of the esophagus", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:5041", 
                        "url": "http://disease-ontology.org/term/DOID:5041", 
                        "resource": "Disease Ontology", 
                        "name": "esophageal cancer", 
                        "description": "A gastrointestinal system cancer that is located_in the esophagus."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "BioXpress"
                }
            ], 
            "url": "http://disease-ontology.org/term/DOID:5041", 
            "significant": "No"
        }
    ], 
    "glycosylation": [
        {
            "site_category": "reported_with_glycan", 
            "evidence": [
                {
                    "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A1A5D9", 
                    "id": "A1A5D9", 
                    "database": "O-GlcNAc Database"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/28411811", 
                    "id": "28411811", 
                    "database": "PubMed"
                }
            ], 
            "subtype": "O-GlcNAcylation", 
            "relation": "attached", 
            "glytoucan_ac": "G49108TO", 
            "type": "O-linked"
        }
    ], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 56834.0, 
        "chemical_mass": 56834.0
    }, 
    "expression_tissue": [
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000007", 
                "uberon": "0000007", 
                "name": "Pituitary gland"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000178", 
                "uberon": "0000178", 
                "name": "Blood"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000458", 
                "uberon": "0000458", 
                "name": "Endocervix"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000458", 
                "uberon": "0000458", 
                "name": "Endocervix"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000473", 
                "uberon": "0000473", 
                "name": "Testis"
            }, 
            "present": "no", 
            "evidence": [
                {
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                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000473", 
                "uberon": "0000473", 
                "name": "Testis"
            }, 
            "present": "yes", 
            "evidence": [
                {
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                    "id": "ENSG00000162069", 
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        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000948", 
                "uberon": "0000948", 
                "name": "Heart"
            }, 
            "present": "no", 
            "evidence": [
                {
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                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000955", 
                "uberon": "0000955", 
                "name": "Brain"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
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                "uberon": "0000955", 
                "name": "Brain"
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            "present": "yes", 
            "evidence": [
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                    "id": "ENSG00000162069", 
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000992", 
                "uberon": "0000992", 
                "name": "Ovary"
            }, 
            "present": "yes", 
            "evidence": [
                {
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                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0000996", 
                "uberon": "0000996", 
                "name": "Vagina"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001043", 
                "uberon": "0001043", 
                "name": "Esophagus"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001150", 
                "uberon": "0001150", 
                "name": "Body of pancreas"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001155", 
                "uberon": "0001155", 
                "name": "Colon"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001160", 
                "uberon": "0001160", 
                "name": "Fundus of stomach"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001161", 
                "uberon": "0001161", 
                "name": "Body of stomach"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001255", 
                "uberon": "0001255", 
                "name": "Urinary bladder"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0001987", 
                "uberon": "0001987", 
                "name": "Placenta"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002046", 
                "uberon": "0002046", 
                "name": "Thyroid gland"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002048", 
                "uberon": "0002048", 
                "name": "Lung"
            }, 
            "present": "yes", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002107", 
                "uberon": "0002107", 
                "name": "Liver"
            }, 
            "present": "no", 
            "evidence": [
                {
                    "url": "https://bgee.org/?page=gene&gene_id=ENSG00000162069", 
                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002107", 
                "uberon": "0002107", 
                "name": "Liver"
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            "evidence": [
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                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002367", 
                "uberon": "0002367", 
                "name": "Prostate gland"
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            "present": "yes", 
            "evidence": [
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                    "id": "ENSG00000162069", 
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            ]
        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0002369", 
                "uberon": "0002369", 
                "name": "Adrenal gland"
            }, 
            "present": "no", 
            "evidence": [
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                    "id": "ENSG00000162069", 
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        }, 
        {
            "tissue": {
                "url": "http://purl.obolibrary.org/obo/UBERON_0009853", 
                "uberon": "0009853", 
                "name": "Body of uterus"
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                    "id": "ENSG00000162069", 
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            ]
        }, 
        {
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                "url": "http://purl.obolibrary.org/obo/UBERON_0009853", 
                "uberon": "0009853", 
                "name": "Body of uterus"
            }, 
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            "evidence": [
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                    "id": "ENSG00000162069", 
                    "database": "Bgee"
                }
            ]
        }
    ], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A1A5D9", 
            "name": "BICDL2", 
            "locus": {
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                "strand": "-", 
                "start_pos": 3036926, 
                "chromosome": "16", 
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            }
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    ], 
    "protein_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1A5D9", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "BICD family-like cargo adapter 2"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1A5D9#names_and_taxonomy", 
            "type": "recommended", 
            "resource": "UniProtKB", 
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        }, 
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        }, 
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        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1A5D9#names_and_taxonomy", 
            "type": "synonym", 
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        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1A5D9", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "coiled-coil domain containing 64B; coiled-coil domain-containing protein 64B; BICD-related protein 2; bicaudal D-related protein 2"
        }
    ]
}
