{ "uniprot_canonical_ac": "A0A571BF63-1", "ptm_annotation": [], "sequence": { "header": "tr|A0A571BF63-1|A0A571BF63_MOUSE Isoform 1 of Ankyrin-repeat and fibronectin type III domain-containing 1 OS=Mus musculus OX=10090 GN=Ankfn1 PE=4 SV=1 CANONICAL=A0A571BF63-1", "length": 1286, "sequence": "MLCLEKLVAVLLKTQRTSDAYKKGPWKSQRYTVSGSRVAYKRLNCDDIWARKKSRRIPMVPGGTYSPMPESQPLEDSPKALPVLGEQSNSDNDINEPVFIWGISDKAAQRKSISAGEGSFRLQQEKQQPLVHRPGRGKGRLRLPHRLPFKDRHFTCSKIIGRRFACFAQRLSYRRKQSQCDLLNESTGHLPATCSSAASKSLSWNYCSKMTQQMQNLHLSQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEAMFEAVEQQDLDAVQLLLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQDRVSELSAQVENEGFTLDNTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEVPANACLMVSSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSKDFSPLAGEIIMDNLQTLRCTITGLTTGQQYFVQVSAYNMKGWGPAQTTTPVCASPSNWKDYDDREPRHKGQSEVLESLLQQVRALHQHYSCRESSKLQTTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYIATIFYYKDNMLVTNEDQIPIVEIDDSHTSSITQDFLWFMKLSCMWEDIRWLRQSVPISMSSSTVLQTRQKMLAATAQLQNLLGTHNLGRLYYEPIKDRHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSHQRLSPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENHNISKEEWEWIQKLSGSESMESVDHNADCPMQLFFYELQMAVAALLKQINIPRHQARNFRLYTQEVLEIGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELVHFCSYREKFISLYCRLSAVVELDSLNTQQSLREAISDSEVAAAKQRHQQVLDFIQQIDEVWREMRWIMDALQYARYKQPVSGLPITKLIDSSSEQNLKKISSTSSHIDCLPSTSPSPEMHRRKAVSESQPCSDEEGCSEVFLPTDSDYDSSDALSPRDLDLVYLSSHDIAQQALSGLSGSAPDVLQVHDMKASMGPGQDPQGPGQGPDTDHSCVEFLHSLTLTGLAPKNHAKMVAGTRPPLGFLGKRKPGKHQHYGGFSRHHRWLRMHSETQSLSLSEGVYTQHLSQACGLAEDPGEAEGPGPVVDGPRGLPLAHAASLPEERRSCLQDPRRPLQRVYVEPYSDTLAGQDPKLWTSLSPTPAGRSSLPSSTSSEMSPDPTSPVSEILSSML" }, "uniprot_id": "A0A571BF63_MOUSE", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A571BF63", "id": "A0A571BF63", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "publication": [], "uniprot_ac": "A0A571BF63", "site_annotation": [ { "end_pos": 186, "annotation": "n_glycosylation_sequon", "start_pos": 184 }, { "end_pos": 242, "annotation": "n_glycosylation_sequon", "start_pos": 240 }, { "end_pos": 787, "annotation": "n_glycosylation_sequon", "start_pos": 785 }, { "end_pos": 857, "annotation": "n_glycosylation_sequon", "start_pos": 855 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A571BF63#A0A140LHQ2-1", "isoform_ac": "A0A140LHQ2-1", "locus": { "end_pos": 89639577, "strand": "+", "start_pos": 89696845, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000207350", "id": "ENSMUST00000207350", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000146500", "id": "ENSMUSP00000146500", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A140LHQ2-1|A0A571BF63_MOUSE Computationally mapped isoform of Ankyrin-repeat and fibronectin type III domain-containing 1 OS=Mus musculus OX=10090 GN=Ankfn1 PE=4 SV=1 CANONICAL=A0A571BF63-1", "length": 48, "sequence": "METSPNRVGKQRLRRFSSHDFHLQTSGLHSTGRKIGCPSKTDILLAAK" } }, { "url": "https://www.uniprot.org/uniprot/A0A571BF63#A0A140LIW7-1", "isoform_ac": "A0A140LIW7-1", "locus": { "end_pos": 89391609, "strand": "+", "start_pos": 89526647, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000207815", "id": "ENSMUST00000207815", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000146987", "id": "ENSMUSP00000146987", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A140LIW7-1|A0A571BF63_MOUSE Computationally mapped isoform of Ankyrin-repeat and fibronectin type III domain-containing 1 OS=Mus musculus OX=10090 GN=Ankfn1 PE=4 SV=1 CANONICAL=A0A571BF63-1", "length": 1083, "sequence": "XNYCSKMTQQMQNLHLSQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEAMFEAVEQQDLDAVQLLLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQDRVSELSAQVENEGFTLDNTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEVPANACLMVSSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSKDFSPLAGEIIMDNLQTLRCTITGLTTGQQYFVQVSAYNMKGWGPAQTTTPVCASPSNWKDYDDREPRHKGQSEVLESLLQQVRALHQHYSCRESSKLQTTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYIATIFYYKDNMLVTNEDQIPIVEIDDSHTSSITQDFLWFMKLSCMWEDIRWLRQSVPISMSSSTVLQTRQKMLAATAQLQNLLGTHNLGRLYYEPIKDRHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSHQRLSPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENHNISKEEWEWIQKLSGSESMESVDHNADCPMQLFFYELQMAVAALLKQINIPRHQARNFRLYTQEVLEIGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELVHFCSYREKFISLYCRLSAVVELDSLNTQQSLREAISDSEVAAAKQRHQQVLDFIQQIDEVWREMRWIMDALQYARYKQPVSGLPITKLIDSSSEQNLKKISSTSSHIDCLPSTSPSPEMHRRKAVSESQPCSDEEGCSEVFLPTDSDYDSSDALSPRDLDLVYLSSHDIAQQALSGLSGSAPDVLQVHDMKASMGPGQDPQGPGQGPDTDHSCVEFLHSLTLTGLAPKNHAKMVAGTRPPLGFLGKRKPGKHQHYGGFSRHHRWLRMHSETQSLSLSEGVYTQHLSQACGLAEDPGEAEGPGPVVDGPRGLPLAHAASLPEERRSCLQDPRRPLQRVYVEPYSDTLAGQDPKLWTSLSPTPAGRSSLPSSTSSEMSPDPTSPVSEILSSML" } }, { "url": "https://www.uniprot.org/uniprot/A0A571BF63#A0A571BF63-1", "isoform_ac": "A0A571BF63-1", "locus": { "end_pos": 89391611, "strand": "+", "start_pos": 89841208, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000238273", "id": "ENSMUST00000238273", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000158789", "id": "ENSMUSP00000158789", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A571BF63-1|A0A571BF63_MOUSE Isoform 1 of Ankyrin-repeat and fibronectin type III domain-containing 1 OS=Mus musculus OX=10090 GN=Ankfn1 PE=4 SV=1 CANONICAL=A0A571BF63-1", "length": 1286, "sequence": "MLCLEKLVAVLLKTQRTSDAYKKGPWKSQRYTVSGSRVAYKRLNCDDIWARKKSRRIPMVPGGTYSPMPESQPLEDSPKALPVLGEQSNSDNDINEPVFIWGISDKAAQRKSISAGEGSFRLQQEKQQPLVHRPGRGKGRLRLPHRLPFKDRHFTCSKIIGRRFACFAQRLSYRRKQSQCDLLNESTGHLPATCSSAASKSLSWNYCSKMTQQMQNLHLSQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEAMFEAVEQQDLDAVQLLLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQDRVSELSAQVENEGFTLDNTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEVPANACLMVSSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSKDFSPLAGEIIMDNLQTLRCTITGLTTGQQYFVQVSAYNMKGWGPAQTTTPVCASPSNWKDYDDREPRHKGQSEVLESLLQQVRALHQHYSCRESSKLQTTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYIATIFYYKDNMLVTNEDQIPIVEIDDSHTSSITQDFLWFMKLSCMWEDIRWLRQSVPISMSSSTVLQTRQKMLAATAQLQNLLGTHNLGRLYYEPIKDRHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSHQRLSPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENHNISKEEWEWIQKLSGSESMESVDHNADCPMQLFFYELQMAVAALLKQINIPRHQARNFRLYTQEVLEIGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELVHFCSYREKFISLYCRLSAVVELDSLNTQQSLREAISDSEVAAAKQRHQQVLDFIQQIDEVWREMRWIMDALQYARYKQPVSGLPITKLIDSSSEQNLKKISSTSSHIDCLPSTSPSPEMHRRKAVSESQPCSDEEGCSEVFLPTDSDYDSSDALSPRDLDLVYLSSHDIAQQALSGLSGSAPDVLQVHDMKASMGPGQDPQGPGQGPDTDHSCVEFLHSLTLTGLAPKNHAKMVAGTRPPLGFLGKRKPGKHQHYGGFSRHHRWLRMHSETQSLSLSEGVYTQHLSQACGLAEDPGEAEGPGPVVDGPRGLPLAHAASLPEERRSCLQDPRRPLQRVYVEPYSDTLAGQDPKLWTSLSPTPAGRSSLPSSTSSEMSPDPTSPVSEILSSML" } }, { "url": "https://www.uniprot.org/uniprot/A0A571BF63#F6RWQ6-1", "isoform_ac": "F6RWQ6-1", "locus": { "end_pos": 89421089, "strand": "+", "start_pos": 89696845, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000128717", "id": "ENSMUST00000128717", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000121290", "id": "ENSMUSP00000121290", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F6RWQ6-1|A0A571BF63_MOUSE Computationally mapped isoform of Ankyrin-repeat and fibronectin type III domain-containing 1 OS=Mus musculus OX=10090 GN=Ankfn1 PE=4 SV=2 CANONICAL=A0A571BF63-1", "length": 763, "sequence": "METSPNRRLPFKDRHFTCSKIIGRRFACFAQRLSYRRKQSQCDLLNESTGHLPATCSSAASKSLSWNYCSKMTQQMQNLHLSQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEAMFEAVEQQDLDAVQLLLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQDRVSELSAQVENEGFTLDNTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEVPANACLMVSSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSKDFSPLAGEIIMDNLQTLRCTITGLTTGQQYFVQVSAYNMKGWGPAQTTTPVCASPSNWKDYDDREPRHKGQSEVLESLLQQVRALHQHYSCRESSKLQTTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYIATIFYYKDNMLVTNEDQIPIVEIDDSHTSSITQDFLWFMKLSCMWEDIRWLRQSVPISMSSSTVLQTRQKMLAATAQLQNLLGTHNLGRLYYEPIKDRHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSHQRLSPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENHNISKEEWEWIQKLSGSESMESVDHNADCPMQLFFYELQMAVAALLKQINIPRHQARNFRLYTQEVLEIGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELGIVACFT" } }, { "url": "https://www.uniprot.org/uniprot/A0A571BF63#F6X7B3-1", "isoform_ac": "F6X7B3-1", "locus": { "end_pos": 89421089, "strand": "+", "start_pos": 89538556, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000169201", "id": "ENSMUST00000169201", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000132133", "id": "ENSMUSP00000132133", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F6X7B3-1|A0A571BF63_MOUSE Computationally mapped isoform of Ankyrin-repeat and fibronectin type III domain-containing 1 OS=Mus musculus OX=10090 GN=Ankfn1 PE=4 SV=1 CANONICAL=A0A571BF63-1", "length": 743, "sequence": "RIGRRFACFAQRLSYRRKQSQCDLLNESTGHLPATCSSAASKSLSWNYCSKMTQQMQNLHLSQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEAMFEAVEQQDLDAVQLLLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQDRVSELSAQVENEGFTLDNTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEVPANACLMVSSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSKDFSPLAGEIIMDNLQTLRCTITGLTTGQQYFVQVSAYNMKGWGPAQTTTPVCASPSNWKDYDDREPRHKGQSEVLESLLQQVRALHQHYSCRESSKLQTTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYIATIFYYKDNMLVTNEDQIPIVEIDDSHTSSITQDFLWFMKLSCMWEDIRWLRQSVPISMSSSTVLQTRQKMLAATAQLQNLLGTHNLGRLYYEPIKDRHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSHQRLSPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENHNISKEEWEWIQKLSGSESMESVDHNADCPMQLFFYELQMAVAALLKQINIPRHQARNFRLYTQEVLEIGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELGIVACFT" } }, { "url": "https://www.uniprot.org/uniprot/A0A571BF63#Q8CDJ6-1", "isoform_ac": "Q8CDJ6-1", "locus": { "end_pos": 89391611, "strand": "+", "start_pos": 89418880, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000050983", "id": "ENSMUST00000050983", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000049776", "id": "ENSMUSP00000049776", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|Q8CDJ6-1|A0A571BF63_MOUSE Computationally mapped isoform of Ankyrin-repeat and fibronectin type III domain-containing 1 OS=Mus musculus OX=10090 GN=Ankfn1 PE=4 SV=1 CANONICAL=A0A571BF63-1", "length": 403, "sequence": "MPLSGPLHTAAVHFCSYREKFISLYCRLSAVVELDSLNTQQSLREAISDSEVAAAKQRHQQVLDFIQQIDEVWREMRWIMDALQYARYKQPVSGLPITKLIDSSSEQNLKKISSTSSHIDCLPSTSPSPEMHRRKAVSESQPCSDEEGCSEVFLPTDSDYDSSDALSPRDLDLVYLSSHDIAQQALSGLSGSAPDVLQVHDMKASMGPGQDPQGPGQGPDTDHSCVEFLHSLTLTGLAPKNHAKMVAGTRPPLGFLGKRKPGKHQHYGGFSRHHRWLRMHSETQSLSLSEGVYTQHLSQACGLAEDPGEAEGPGPVVDGPRGLPLAHAASLPEERRSCLQDPRRPLQRVYVEPYSDTLAGQDPKLWTSLSPTPAGRSSLPSSTSSEMSPDPTSPVSEILSSML" } } ], "pathway": [], "function": [], "orthologs": [], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "refseq": {}, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001662", "pmid": "26131556", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A571BF63", "id": "A0A571BF63", "database": "UniProtKB" } ], "name": "behavioral fear response", "id": "GO:0001662" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045475", "pmid": "26131556", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A571BF63", "id": "A0A571BF63", "database": "UniProtKB" } ], "name": "locomotor rhythm", "id": "GO:0045475" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050957", "pmid": "26131556", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A571BF63", "id": "A0A571BF63", "database": "UniProtKB" } ], "name": "equilibrioception", "id": "GO:0050957" } ], "total": 3, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.uniprot.org/uniprot/A0A571BF63", "type": "recommended", "resource": "UniProtKB", "name": "Ankfn1" } ], "pro_annotation": [], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "id": "cd00063", "database": "CDD" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "id": "IPR002110", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "id": "IPR003961", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "id": "IPR013783", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR020683", "id": "IPR020683", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "id": "IPR036116", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "id": "IPR036770", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR039269", "id": "IPR039269", "database": "InterPro" }, { "url": "http://www.informatics.jax.org/marker/MGI:2686021", "id": "2686021", "database": "MGI" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21437", "id": "PTHR21437", "database": "PANTHER" }, { "url": "http://pfam.xfam.org/family/PF00041", "id": "PF00041", "database": "Pfam" }, { "url": "https://www.uniprot.org/uniprot/A0A571BF63", "id": "A0A571BF63", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 145202.0, "chemical_mass": 145202.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A571BF63", "name": "Ankfn1", "locus": { "end_pos": 89390223, "strand": "-", "start_pos": 89777653, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000047773", "id": "ENSMUSG00000047773", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A0A571BF63#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "Ankyrin-repeat and fibronectin type III domain-containing 1" } ] }