{
    "uniprot_canonical_ac": "A0A1W2PRG0-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A0A1W2PRG0-1|A0A1W2PRG0_HUMAN Isoform 1 of Glutathione transferase  OS=Homo sapiens OX=9606 GN= PE=3 SV=1 CANONICAL=A0A1W2PRG0-1", 
        "length": 241, 
        "sequence": "MALELYMDLLSAPCRAVYIFSKKHDIQFNFQFVDLLKGHHHSKGYIDINPLRKLPSLKDGKFILSESAAILYYLCRKYSAPSHWCPPDPHARARVDEFVAWQHTAFQLPMKKIVWLKLLIPKITGKEVSAEKMEHAVEEVKNSLQLFEEYFLQDKMFITGNQISLADLVAVVEMMQPMAANYNVFLNSSKLAEWRMRVELNIGCGLFREAHDRLMQLADWDFSTLDPMVTRKICEFREKYL"
    }, 
    "uniprot_id": "A0A1W2PRG0_HUMAN", 
    "enzyme_annotation": [
        {
            "ec": "2.5.1.18", 
            "activity": ""
        }, 
        {
            "ec": "2.5.1.18", 
            "activity": "RX + glutathione = HX + R-S-glutathione."
        }
    ], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Human", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A1W2PRG0", 
                    "id": "A0A1W2PRG0", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "publication": [], 
    "uniprot_ac": "A0A1W2PRG0", 
    "site_annotation": [
        {
            "end_pos": 189, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 187
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A1W2PRG0#A0A1W2PRG0-1", 
            "isoform_ac": "A0A1W2PRG0-1", 
            "locus": {
                "end_pos": 24052468, 
                "strand": "+", 
                "start_pos": 24059615, 
                "chromosome": "22", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000625476", 
                        "id": "ENST00000625476", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000492227", 
                        "id": "ENSP00000492227", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A1W2PRG0-1|A0A1W2PRG0_HUMAN Isoform 1 of Glutathione transferase  OS=Homo sapiens OX=9606 GN= PE=3 SV=1 CANONICAL=A0A1W2PRG0-1", 
                "length": 241, 
                "sequence": "MALELYMDLLSAPCRAVYIFSKKHDIQFNFQFVDLLKGHHHSKGYIDINPLRKLPSLKDGKFILSESAAILYYLCRKYSAPSHWCPPDPHARARVDEFVAWQHTAFQLPMKKIVWLKLLIPKITGKEVSAEKMEHAVEEVKNSLQLFEEYFLQDKMFITGNQISLADLVAVVEMMQPMAANYNVFLNSSKLAEWRMRVELNIGCGLFREAHDRLMQLADWDFSTLDPMVTRKICEFREKYL"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [], 
    "refseq": {}, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004364", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1W2PRG0", 
                                "id": "A0A1W2PRG0", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "glutathione transferase activity", 
                        "id": "GO:0004364"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1W2PRG0", 
                                "id": "A0A1W2PRG0", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006749", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A1W2PRG0", 
                                "id": "A0A1W2PRG0", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "glutathione metabolic process", 
                        "id": "GO:0006749"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A1W2PRG0", 
            "id": "A0A1W2PRG0", 
            "database": "BioMuta"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03183", 
            "id": "cd03183", 
            "database": "CDD"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR004045", 
            "id": "IPR004045", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR004046", 
            "id": "IPR004046", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR010987", 
            "id": "IPR010987", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036249", 
            "id": "IPR036249", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036282", 
            "id": "IPR036282", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR040077", 
            "id": "IPR040077", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR040079", 
            "id": "IPR040079", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00043", 
            "id": "PF00043", 
            "database": "Pfam"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF13417", 
            "id": "PF13417", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A1W2PRG0", 
            "id": "A0A1W2PRG0", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 28136.0, 
        "chemical_mass": 28136.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A1W2PRG0", 
            "name": "", 
            "locus": {}
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A1W2PRG0#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "2.5.1.18"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A1W2PRG0#names_and_taxonomy", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Glutathione transferase"
        }
    ]
}