{ "uniprot_canonical_ac": "A0A1B0GWS0-1", "ptm_annotation": [], "sequence": { "header": "tr|A0A1B0GWS0-1|A0A1B0GWS0_RAT Isoform 1 of PTPRF-interacting protein alpha 1 OS=Rattus norvegicus OX=10116 GN=Ppfia1 PE=1 SV=1 CANONICAL=A0A1B0GWS0-1", "length": 1266, "sequence": "MMCEVMPTISEAEGPPGGGGSHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNSQKKALTEGMLDGNHEQENAPSTNGKRSSDGSLSHEDLAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQREVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKSGPLSSGSSAAKEAKLLELTSKLRKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALKAELEQMRLRGSSLHHGRPHLGSVPDFRFSVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPPYPASSLAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLPSDLRKHRRQLPASREEVRDDKTTIKCETSPPSSPRPLRLDRLHKGALHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQAGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTTGNVWLTHEEMETLTATPQTEDEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEFANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDGSVSGAQRLDSATVRTYSC" }, "uniprot_id": "A0A1B0GWS0_RAT", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Rat", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0", "id": "A0A1B0GWS0", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "publication": [], "uniprot_ac": "A0A1B0GWS0", "site_annotation": [ { "end_pos": 1109, "annotation": "n_glycosylation_sequon", "start_pos": 1107 }, { "end_pos": 121, "annotation": "n_glycosylation_sequon", "start_pos": 119 }, { "end_pos": 808, "annotation": "n_glycosylation_sequon", "start_pos": 806 }, { "end_pos": 824, "annotation": "n_glycosylation_sequon", "start_pos": 822 }, { "end_pos": 873, "annotation": "n_glycosylation_sequon", "start_pos": 871 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0#A0A0G2K3L9-1", "isoform_ac": "A0A0G2K3L9-1", "locus": { "end_pos": 217646609, "strand": "+", "start_pos": 217720221, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000078810", "id": "ENSRNOT00000078810", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000072693", "id": "ENSRNOP00000072693", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2K3L9-1|A0A1B0GWS0_RAT Computationally mapped isoform of PTPRF-interacting protein alpha 1 OS=Rattus norvegicus OX=10116 GN=Ppfia1 PE=1 SV=1 CANONICAL=A0A1B0GWS0-1", "length": 1226, "sequence": "MMCEVMPTISEAEGPPGGGGSHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNSQKKALTEGMLDGNHEQENAPSTNGKRSSDGSLSHEDLAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQREVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKSGPLSSGSSAAKEAKLLELTSKLRKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALKAELEQMRLRGSSLHHGRPHLGSVPDFRFSVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPPYPASSLAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLLPASREEVRDDKTTIKCETSPPSSPRPLRLDRLHKGALHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQAGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEFANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDGSVSGAQRLDSATVRTYSC" } }, { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0#A0A1B0GWM2-1", "isoform_ac": "A0A1B0GWM2-1", "locus": { "end_pos": 217646609, "strand": "+", "start_pos": 217720221, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000092748", "id": "ENSRNOT00000092748", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000075947", "id": "ENSRNOP00000075947", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A1B0GWM2-1|A0A1B0GWS0_RAT Computationally mapped isoform of PTPRF-interacting protein alpha 1 OS=Rattus norvegicus OX=10116 GN=Ppfia1 PE=1 SV=1 CANONICAL=A0A1B0GWS0-1", "length": 1241, "sequence": "MMCEVMPTISEAEGPPGGGGSHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNSQKKALTEGMLDGNHEQENAPSTNGKRSSDGSLSHEDLAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQREVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALKAELEQMRLRGSSLHHGRPHLGSVPDFRFSVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPPYPASSLAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLPSDLRKHRRQLPASREEVRDDKTTIKCETSPPSSPRPLRLDRLHKGALHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQAGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTTGNVWLTHEEMETLTATPQTEDEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEFANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDGSVSGAQRLDSATVRTYSC" } }, { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0#A0A1B0GWS0-1", "isoform_ac": "A0A1B0GWS0-1", "locus": { "end_pos": 217646609, "strand": "+", "start_pos": 217720221, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000092939", "id": "ENSRNOT00000092939", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000075999", "id": "ENSRNOP00000075999", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A1B0GWS0-1|A0A1B0GWS0_RAT Isoform 1 of PTPRF-interacting protein alpha 1 OS=Rattus norvegicus OX=10116 GN=Ppfia1 PE=1 SV=1 CANONICAL=A0A1B0GWS0-1", "length": 1266, "sequence": "MMCEVMPTISEAEGPPGGGGSHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNSQKKALTEGMLDGNHEQENAPSTNGKRSSDGSLSHEDLAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQREVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKSGPLSSGSSAAKEAKLLELTSKLRKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALKAELEQMRLRGSSLHHGRPHLGSVPDFRFSVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPPYPASSLAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLPSDLRKHRRQLPASREEVRDDKTTIKCETSPPSSPRPLRLDRLHKGALHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQAGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTTGNVWLTHEEMETLTATPQTEDEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEFANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDGSVSGAQRLDSATVRTYSC" } }, { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0#A0A1B0GWW5-1", "isoform_ac": "A0A1B0GWW5-1", "locus": { "end_pos": 217646608, "strand": "+", "start_pos": 217677997, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000092824", "id": "ENSRNOT00000092824", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000076045", "id": "ENSRNOP00000076045", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A1B0GWW5-1|A0A1B0GWS0_RAT Computationally mapped isoform of PTPRF-interacting protein alpha 1 OS=Rattus norvegicus OX=10116 GN=Ppfia1 PE=1 SV=1 CANONICAL=A0A1B0GWS0-1", "length": 736, "sequence": "XERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALKAELEQMRLRGSSLHHGRPHLGSVPDFRFSVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPPYPASSLAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLLPASREEVRDDKTTIKCETSPPSSPRPLRLDRLHKGALHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQAGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEFANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDGSVSGAQRLDSATVRTYSC" } }, { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0#D3ZZ81-1", "isoform_ac": "D3ZZ81-1", "locus": { "end_pos": 217645478, "strand": "+", "start_pos": 217720221, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000039677", "id": "ENSRNOT00000039677", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000032648", "id": "ENSRNOP00000032648", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|D3ZZ81-1|A0A1B0GWS0_RAT Computationally mapped isoform of PTPRF-interacting protein alpha 1 OS=Rattus norvegicus OX=10116 GN=Ppfia1 PE=1 SV=1 CANONICAL=A0A1B0GWS0-1", "length": 1190, "sequence": "MMCEVMPTISEAEGPPGGGGSHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNSQKKALTEGMLDGNHEQENAPSTNGKRSSDGSLSHEDLAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQREVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVLNIEALKAELEQMRLRGSSLHHGRPHLGSVPDFRFSVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPPYPASSLAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLLPASREEVRDDKTTIKCETSPPSSPRPLRLDRLHKGALHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQAGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEFANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVTGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDVYPHYFYR" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-181429", "resource": "Reactome", "id": "R-RNO-181429", "name": "Serotonin Neurotransmitter Release Cycle" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-181430", "resource": "Reactome", "id": "R-RNO-181430", "name": "Norepinephrine Neurotransmitter Release Cycle" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-210500", "resource": "Reactome", "id": "R-RNO-210500", "name": "Glutamate Neurotransmitter Release Cycle" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-212676", "resource": "Reactome", "id": "R-RNO-212676", "name": "Dopamine Neurotransmitter Release Cycle" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-264642", "resource": "Reactome", "id": "R-RNO-264642", "name": "Acetylcholine Neurotransmitter Release Cycle" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-388844", "resource": "Reactome", "id": "R-RNO-388844", "name": "Receptor-type tyrosine-protein phosphatases" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "B2RXQ2-1", "protein_name": "Ppfia1 protein", "sequence": { "length": 1266, "sequence": "MMCEVMPTISEAEGPPGGGGSHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGLLDGNHEQESAPSTNGKRSSDGSLSHEDLAKVLELQEVIDRQAREQSQMKERLASLSSHAAELEEDLDTARKDLIKSEEMNTKLQREVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKSGPLSSGSSAAKEAKLLELTSKLRKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVENAKKQLEETQHDKDQLVVTIEALKAELEQMRLRGPSLHHGRPHLGSVPDFRFSVADGHVDAYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDVDVSDGEDDRDTLLSSVDLLSPSGQADAQTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPPYPASSLAGSSPPGSGRSTPRRVPHSPAREVDRLGVMTLPSDLRKHRRQLPASREEVRDDKTTIKCETSPPSSPRPLRLDRMHKGAPHTVSHEDIRDLRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGPLGKESPGQVGVSETENSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTTGNVWLTHEEMETLTATPQTEDEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQNETRDVLVWSNDRVIRWILSIGLKEYANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLITGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLASGSAETLPANFRVTSSMSSPSMQPKKVQMDGSVSGAQRLDSATVRTYSC" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/20802", "id": "20802", "database": "MGI" } ], "common_name": "Mouse", "organism": "Mus musculus", "gene_name": "Ppfia1", "tax_id": 10090 }, { "uniprot_canonical_ac": "Q13136-1", "protein_name": "Liprin-alpha-1", "sequence": { "length": 1202, "sequence": "MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVESAKKQLEETQHDKDQLVLNIEALRAELDHMRLRGASLHHGRPHLGSVPDFRFPMADGHTDSYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDADVSDGEDDRDTLLSSVDLLSPSGQADAHTLAMMLQEQLDAINKEIRLIQEEKENTEQRAEEIESRVGSGSLDNLGRFRSMSSIPPYPASSLASSSPPGSGRSTPRRIPHSPAREVDRLGVMTLLPPSREEVRDDKTTIKCETSPPSSPRALRLDRLHKGALHTVSHEDIRDIRNSTGSQDGPVSNPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGQTGKEALGQAGVSETDNSSQDALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYVAACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTTLAYGDMNHEWIGNEWLPSLGLPQYRSYFMECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQSEIKDVLVWSNDRVIRWILSIGLKEYANNLIESGVHGALLALDETFDFSALALLLQIPTQNTQARAVLEREFNNLLVMGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLAAGSAETLPANFRVTSSMSSPSMQPKKMQMDGNVSGTQRLDSATVRTYSC" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/20802", "id": "20802", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "gene_name": "PPFIA1", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006230777.1", "ac": "XP_006230777.1", "name": "liprin-alpha-1 isoform X1", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "pmid": "12522103", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0", "id": "A0A1B0GWS0", "database": "UniProtKB" } ], "name": "axon", "id": "GO:0030424" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "pmid": "12522103", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0", "id": "A0A1B0GWS0", "database": "UniProtKB" } ], "name": "dendrite", "id": "GO:0030425" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048786", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0", "id": "A0A1B0GWS0", "database": "UniProtKB" } ], "name": "presynaptic active zone", "id": "GO:0048786" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "pmid": "12522103", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0", "id": "A0A1B0GWS0", "database": "UniProtKB" } ], "name": "protein-containing complex", "id": "GO:0032991" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0", "id": "A0A1B0GWS0", "database": "UniProtKB" } ], "name": "cytosol", "id": "GO:0005829" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0", "id": "A0A1B0GWS0", "database": "UniProtKB" } ], "name": "focal adhesion", "id": "GO:0005925" } ], "total": 6, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0", "id": "A0A1B0GWS0", "database": "UniProtKB" } ], "name": "synapse organization", "id": "GO:0050808" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903077", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0", "id": "A0A1B0GWS0", "database": "UniProtKB" } ], "name": "negative regulation of protein localization to plasma membrane", "id": "GO:1903077" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051497", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0", "id": "A0A1B0GWS0", "database": "UniProtKB" } ], "name": "negative regulation of stress fiber assembly", "id": "GO:0051497" } ], "total": 3, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A1B0GWS0", "type": "synonym", "resource": "RefSeq", "name": "Ppfia1" }, { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0", "type": "recommended", "resource": "UniProtKB", "name": "Ppfia1" } ], "pro_annotation": [], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09562", "id": "cd09562", "database": "CDD" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09565", "id": "cd09565", "database": "CDD" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09568", "id": "cd09568", "database": "CDD" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/293645", "id": "293645", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "id": "IPR001660", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "id": "IPR013761", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR029515", "id": "IPR029515", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR030438", "id": "IPR030438", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR037620", "id": "IPR037620", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR037621", "id": "IPR037621", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR037622", "id": "IPR037622", "database": "InterPro" }, { "url": "http://www.orthodb.org/?query=440941at2759", "id": "440941at2759", "database": "OrthoDB" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587", "id": "PTHR12587", "database": "PANTHER" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12587:SF15", "id": "PTHR12587:SF15", "database": "PANTHER" }, { "url": "http://pfam.xfam.org/family/PF00536", "id": "PF00536", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF07647", "id": "PF07647", "database": "Pfam" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-181429", "id": "R-RNO-181429", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-181430", "id": "R-RNO-181430", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-210500", "id": "R-RNO-210500", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-212676", "id": "R-RNO-212676", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-264642", "id": "R-RNO-264642", "database": "Reactome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-388844", "id": "R-RNO-388844", "database": "Reactome" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006230777.1", "id": "XP_006230777.1", "database": "RefSeq" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1309009", "id": "1309009", "database": "RGD" }, { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0", "id": "A0A1B0GWS0", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 142635.0, "chemical_mass": 142635.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0", "name": "Ppfia1", "locus": { "end_pos": 217644224, "strand": "-", "start_pos": 217721376, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000020857", "id": "ENSRNOG00000020857", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A0A1B0GWS0#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "PTPRF-interacting protein alpha 1" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A1B0GWS0", "type": "synonym", "resource": "RefSeq", "name": "liprin-alpha-1 isoform X1" } ] }