{
    "uniprot_canonical_ac": "A0A1B0GVR7-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A0A1B0GVR7-1|F240C_HUMAN Isoform 1 of Protein FAM240C  OS=Homo sapiens OX=9606 GN=FAM240C PE=3 SV=1 CANONICAL=A0A1B0GVR7-1", 
        "length": 95, 
        "sequence": "MVGKNMSKSLTLKNPGRVAYDSGGIKMFWEKKIEHHARHLQNEDIRVRRSALNKLRVGWAEQLEGRNKMLQGPGRCPDRVPEATESLHTKDKKAA"
    }, 
    "uniprot_id": "F240C_HUMAN", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Human", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A1B0GVR7", 
                    "id": "A0A1B0GVR7", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "publication": [], 
    "uniprot_ac": "A0A1B0GVR7", 
    "site_annotation": [
        {
            "end_pos": 7, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 5
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A1B0GVR7#A0A1B0GUP9-1", 
            "isoform_ac": "A0A1B0GUP9-1", 
            "locus": {
                "end_pos": 241894216, 
                "strand": "+", 
                "start_pos": 241897331, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000401641", 
                        "id": "ENST00000401641", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000490196", 
                        "id": "ENSP00000490196", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A1B0GUP9-1|F240C_HUMAN Computationally mapped isoform of Protein FAM240C  OS=Homo sapiens OX=9606 GN=FAM240C PE=3 SV=1 CANONICAL=A0A1B0GVR7-1", 
                "length": 90, 
                "sequence": "MSKSLTLKNPGRVAYDSGGIKMFWEKKIEHHARHLQNEDIRVRRSALNKLRVGWAEQLEGRNKMLQGPGRCPDRVPEATESLHTKDKKAA"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A1B0GVR7#A0A1B0GVR7-1", 
            "isoform_ac": "A0A1B0GVR7-1", 
            "locus": {
                "end_pos": 241894216, 
                "strand": "+", 
                "start_pos": 241900369, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000404031", 
                        "id": "ENST00000404031", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000490626", 
                        "id": "ENSP00000490626", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A0A1B0GVR7-1|F240C_HUMAN Isoform 1 of Protein FAM240C  OS=Homo sapiens OX=9606 GN=FAM240C PE=3 SV=1 CANONICAL=A0A1B0GVR7-1", 
                "length": 95, 
                "sequence": "MVGKNMSKSLTLKNPGRVAYDSGGIKMFWEKKIEHHARHLQNEDIRVRRSALNKLRVGWAEQLEGRNKMLQGPGRCPDRVPEATESLHTKDKKAA"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [
        {
            "sequence_org": "R", 
            "start_pos": 56, 
            "alt_nt": "A", 
            "chr_id": "2", 
            "ref_nt": "G", 
            "chr_pos": "242836486", 
            "disease": [
                {
                    "synonyms": [], 
                    "recommended_name": {
                        "id": "DOID:1324", 
                        "url": "http://disease-ontology.org/term/DOID:1324", 
                        "resource": "Disease Ontology", 
                        "name": "lung cancer", 
                        "description": "A respiratory system cancer that is located_in the lung."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A1B0GVR7", 
                    "id": "A0A1B0GVR7", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "2.6", 
            "sequence_mut": "C", 
            "subjects_tested": "38", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (2.6%).", 
            "end_pos": 56, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }
    ], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }
    ], 
    "refseq": {}, 
    "go_annotation": {}, 
    "gene_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A1B0GVR7", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "FAM240C"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A1B0GVR7", 
            "id": "A0A1B0GVR7", 
            "database": "BioMuta"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=FAM240C", 
            "id": "FAM240C", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=54200", 
            "id": "54200", 
            "database": "HGNC"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR040261", 
            "id": "IPR040261", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A0A1B0GVR7", 
            "id": "NX_A0A1B0GVR7", 
            "database": "neXtProt"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR40387", 
            "id": "PTHR40387", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://purl.obolibrary.org/obo/PR_PR_A0A1B0GVR7", 
            "id": "PR_A0A1B0GVR7", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A1B0GVR7", 
            "id": "A0A1B0GVR7", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 10834.0, 
        "chemical_mass": 10834.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A1B0GVR7", 
            "name": "FAM240C", 
            "locus": {}
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A1B0GVR7#names_and_taxonomy", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Protein FAM240C"
        }
    ]
}