{ "uniprot_canonical_ac": "A0A0G2QC52-1", "ptm_annotation": [], "sequence": { "header": "tr|A0A0G2QC52-1|A0A0G2QC52_RAT Isoform 1 of RAB, member of RAS oncogene family-like 2 OS=Rattus norvegicus OX=10116 GN=Rabl2 PE=1 SV=1 CANONICAL=A0A0G2QC52-1", "length": 250, "sequence": "MKTVTVTEGFHYGDKTPRLTLVHGHELMAGDRSKQGELDQEKYDAHENVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFRPEIPCILVANKIDADIQMTQKNFSFAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVAYKKSSQDFMDEVLQELENFKLEQKEEDTPDQEQGDMSKSPSPS" }, "uniprot_id": "A0A0G2QC52_RAT", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Rat", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "publication": [], "uniprot_ac": "A0A0G2QC52", "site_annotation": [ { "end_pos": 174, "annotation": "n_glycosylation_sequon", "start_pos": 172 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52#A0A0G2QC52-1", "isoform_ac": "A0A0G2QC52-1", "locus": { "end_pos": 130556855, "strand": "+", "start_pos": 130564406, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000044262", "id": "ENSRNOT00000044262", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000040188", "id": "ENSRNOP00000040188", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2QC52-1|A0A0G2QC52_RAT Isoform 1 of RAB, member of RAS oncogene family-like 2 OS=Rattus norvegicus OX=10116 GN=Rabl2 PE=1 SV=1 CANONICAL=A0A0G2QC52-1", "length": 250, "sequence": "MKTVTVTEGFHYGDKTPRLTLVHGHELMAGDRSKQGELDQEKYDAHENVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFRPEIPCILVANKIDADIQMTQKNFSFAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVAYKKSSQDFMDEVLQELENFKLEQKEEDTPDQEQGDMSKSPSPS" } } ], "pathway": [], "function": [], "orthologs": [ { "uniprot_canonical_ac": "E9Q9D5-2", "protein_name": "Rab-like protein 2A", "sequence": { "length": 223, "sequence": "MAGDRNRHCELEQEKYDTHENVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKITYKNLGTWYAELREFRPEIPCILVANKIDADIQMTQKNFSFAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVAYKESSQDFMDEVLQELENFKLEQKEEDTSGQEQSDTTKSPSPS" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/90913", "id": "90913", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A0A0G2QC52/", "id": "A0A0G2QC52", "database": "OMA" } ], "common_name": "Mouse", "organism": "Mus musculus", "gene_name": "Rabl2", "tax_id": 10090 }, { "uniprot_canonical_ac": "Q9UBK7-1", "protein_name": "Rab-like protein 2A", "sequence": { "length": 228, "sequence": "MAEDKTKPSELDQGKYDADDNVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDIQRKVTYRNLSTWYTELREFRPEIPCIVVANKIDDINVTQKSFNFAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVSYKQNSQDFMDEIFQELENFSLEQEEEDVPDQEQSSSIETPSEEVASPHS" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/90913", "id": "90913", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "gene_name": "RABL2A", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006242287.1", "ac": "XP_006242287.1", "name": "rab-like protein 2B isoform X1", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "GTPase activity", "id": "GO:0003924" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "GTP binding", "id": "GO:0005525" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "endomembrane system", "id": "GO:0012505" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005814", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "centriole", "id": "GO:0005814" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "ciliary basal body", "id": "GO:0036064" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097225", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "sperm midpiece", "id": "GO:0097225" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000242", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "pericentriolar material", "id": "GO:0000242" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030992", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "intraciliary transport particle B", "id": "GO:0030992" } ], "total": 7, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "intracellular protein transport", "id": "GO:0006886" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "flagellated sperm motility", "id": "GO:0030317" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "single fertilization", "id": "GO:0007338" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "cilium assembly", "id": "GO:0060271" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042073", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "intraciliary transport", "id": "GO:0042073" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008594", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "name": "photoreceptor cell morphogenesis", "id": "GO:0008594" } ], "total": 6, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A0G2QC52", "type": "synonym", "resource": "RefSeq", "name": "Rabl2a" }, { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "type": "synonym", "resource": "UniProtKB", "name": "Rabl2a" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A0G2QC52", "type": "synonym", "resource": "RefSeq", "name": "Rabl2b" }, { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "type": "recommended", "resource": "UniProtKB", "name": "Rabl2" } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000013947", "id": "ENSRNOG00000013947", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04124", "id": "cd04124", "database": "CDD" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/362987", "id": "362987", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "id": "IPR001806", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "id": "IPR005225", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "id": "IPR027417", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR041835", "id": "IPR041835", "database": "InterPro" }, { "url": "https://omabrowser.org/oma/group/DGYKPQQ/", "id": "DGYKPQQ", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=1340129at2759", "id": "1340129at2759", "database": "OrthoDB" }, { "url": "http://pfam.xfam.org/family/PF00071", "id": "PF00071", "database": "Pfam" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006242287.1", "id": "XP_006242287.1", "database": "RefSeq" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1306749", "id": "1306749", "database": "RGD" }, { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "id": "A0A0G2QC52", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 28558.0, "chemical_mass": 28558.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52", "name": "Rabl2", "locus": { "end_pos": 130556047, "strand": "-", "start_pos": 130564719, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000013947", "id": "ENSRNOG00000013947", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2QC52#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "RAB, member of RAS oncogene family-like 2" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A0G2QC52", "type": "synonym", "resource": "RefSeq", "name": "rab-like protein 2B isoform X1" } ] }