{ "uniprot_canonical_ac": "A0A0G2KA38-1", "ptm_annotation": [], "sequence": { "header": "tr|A0A0G2KA38-1|A0A0G2KA38_RAT Isoform 1 of Interferon-stimulated exonuclease gene 20 OS=Rattus norvegicus OX=10116 GN=Isg20 PE=4 SV=1 CANONICAL=A0A0G2KA38-1", "length": 185, "sequence": "MADSPEVGRALVAMDCEMVGLGPQRVSGLARCSIVNVHSAVLYDKYIQPEGEITDYRTQVSGITPQHMARATPFAEARLEILQLLKGKLVVGHDLKHDFSALKEDMRKYTIYDTSTDMLLWHEAKLHCYSRVSLRLLCKRLLHKSIQNNWRGHCSVEDARATMELYKISQRLRAQRGLPCLGTSA" }, "uniprot_id": "A0A0G2KA38_RAT", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Rat", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "publication": [], "uniprot_ac": "A0A0G2KA38", "site_annotation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38#A0A0G2JUC4-1", "isoform_ac": "A0A0G2JUC4-1", "locus": { "end_pos": 140602617, "strand": "-", "start_pos": 140608678, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000085570", "id": "ENSRNOT00000085570", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000069045", "id": "ENSRNOP00000069045", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2JUC4-1|A0A0G2KA38_RAT Computationally mapped isoform of Interferon-stimulated exonuclease gene 20 OS=Rattus norvegicus OX=10116 GN=Isg20 PE=4 SV=1 CANONICAL=A0A0G2KA38-1", "length": 172, "sequence": "MDCEMVGLGPQRVSGLARCSIVNVHSAVLYDKYIQPEGEITDYRTQVSGITPQHMARATPFAEARLEILQLLKGKLVVGHDLKHDFSALKEDMRKYTIYDTSTDMLLWHEAKLHCYSRVSLRLLCKRLLHKSIQNNWRGHCSVEDARATMELYKISQRLRAQRGLPCLGTSA" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38#A0A0G2KA38-1", "isoform_ac": "A0A0G2KA38-1", "locus": { "end_pos": 140602577, "strand": "-", "start_pos": 140608678, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000091588", "id": "ENSRNOT00000091588", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000075245", "id": "ENSRNOP00000075245", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2KA38-1|A0A0G2KA38_RAT Isoform 1 of Interferon-stimulated exonuclease gene 20 OS=Rattus norvegicus OX=10116 GN=Isg20 PE=4 SV=1 CANONICAL=A0A0G2KA38-1", "length": 185, "sequence": "MADSPEVGRALVAMDCEMVGLGPQRVSGLARCSIVNVHSAVLYDKYIQPEGEITDYRTQVSGITPQHMARATPFAEARLEILQLLKGKLVVGHDLKHDFSALKEDMRKYTIYDTSTDMLLWHEAKLHCYSRVSLRLLCKRLLHKSIQNNWRGHCSVEDARATMELYKISQRLRAQRGLPCLGTSA" } } ], "pathway": [], "function": [], "orthologs": [], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "refseq": {}, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008310", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "single-stranded DNA 3'-5' exodeoxyribonuclease activity", "id": "GO:0008310" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030620", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "U2 snRNA binding", "id": "GO:0030620" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004527", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "exonuclease activity", "id": "GO:0004527" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "3'-5'-exoribonuclease activity", "id": "GO:0000175" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034511", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "U3 snoRNA binding", "id": "GO:0034511" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030619", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "U1 snRNA binding", "id": "GO:0030619" } ], "total": 6, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "nucleus", "id": "GO:0005634" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "nucleolus", "id": "GO:0005730" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016605", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "PML body", "id": "GO:0016605" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015030", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "Cajal body", "id": "GO:0015030" } ], "total": 5, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000738", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "DNA catabolic process, exonucleolytic", "id": "GO:0000738" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051607", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "defense response to virus", "id": "GO:0051607" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045071", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "negative regulation of viral genome replication", "id": "GO:0045071" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009615", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "response to virus", "id": "GO:0009615" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006401", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "name": "RNA catabolic process", "id": "GO:0006401" } ], "total": 5, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "type": "recommended", "resource": "UniProtKB", "name": "Isg20" } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000054561", "id": "ENSRNOG00000054561", "database": "Bgee" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "id": "IPR012337", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR013520", "id": "IPR013520", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "id": "IPR036397", "database": "InterPro" }, { "url": "https://omabrowser.org/oma/group/DTSTDWV/", "id": "DTSTDWV", "database": "OMA" }, { "url": "http://pfam.xfam.org/family/PF00929", "id": "PF00929", "database": "Pfam" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1306407", "id": "1306407", "database": "RGD" }, { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "id": "A0A0G2KA38", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 20911.0, "chemical_mass": 20911.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38", "name": "Isg20", "locus": { "end_pos": 140608946, "strand": "+", "start_pos": 140601791, "chromosome": "1", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000054561", "id": "ENSRNOG00000054561", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2KA38#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "Interferon-stimulated exonuclease gene 20" } ] }