{ "uniprot_canonical_ac": "A0A0G2K548-1", "ptm_annotation": [], "sequence": { "header": "tr|A0A0G2K548-1|A0A0G2K548_RAT Isoform 1 of A-kinase-anchoring protein 9 OS=Rattus norvegicus OX=10116 GN=Akap9 PE=1 SV=1 CANONICAL=A0A0G2K548-1", "length": 3847, "sequence": "MEDEERQRKLAAGKAKLARFRQRKAQCDGDIPKKQKKKRTPSSKQDSSLHTDQQSAEICSESSQRADSAGSPDSSSAEKAKHGQVFAADPESEISTTADECSSEINGCNSVTKPGNPTDTLREEDFSIDDSYSEQGAQSSQTCLQMGENELAEKQHEVEELTQELEEMRASFGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARKEKDDTTIEFLELTEQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTLQQQLQDYQKKEEDVQAQISFLQEKIRMLEMEKDRKVESLNTKEIEEKQAIIEELNTRVIEEERKTAELENKVTTADELLGQLQGQVTEKDQEIKSLKLELVNSQQNERKCSEEIKELMRTVEELQKRNLKDSQLGTGTVRRVEQETQRKLSLLQAELDEMYGKQIVQMKQELMKQHMSQIEELKSQHKRDLENTLKSDASTTVSKEQVNLMSAAISELNVRLQDTHAQKEKLKGELGAALGEKSALQSQFEDLLEEVRFLREQVQKARQTIAEQENRLSDARKSLSTVEDLKAEIVAASESRKELEVKHEAEITNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEVEHRINVEKLKDNLGIHYKQQIDGLQNEMNRKMETMQCETDNLITRQNQLILENSKLRDLQEHLVNSKSEEMNLQINELQKEIEILRREEKEKGSLEQEVQGLQLKTEQLERQLKEKGDDLQEKCAQLDAENSVLKDEKKALEDMLKMYTPLDQEDPSTRKSEDPRWQKEVGMLRKENEDLQQQCLHLSEEIEKQKNTFAFAEKNFEVNYQELQREYTCLLKIRDDLEDTLAKQALQYESKLSALEEELHSQRGSPTTPPKGENSGFAANRTFPLEPLEVGEVVEKDTTELMEKLEVTRREKLELSEKVSGLSEQLKQTHGTIDSLSEEVRALKQEKEQLLLRCGELELLTNANGTENASVCPVQRSPYQAGPVMGTVRDSQGPISKVSEDLAEESKPMTEDKIPFKESGREPLLLPTRTKKPSRVTVEPCESEKLQQELYALKAEQDDLRLQMEAQRLCLFVVYSTHADQVRAYMEKEREEALCSLKDELVSAQQKKIDELHKIHQCQLQHVKVQETGNEPLQVLIERLQKAVSEKCFHISKTLNNVFDECYTPLKCEMNIEEKENSGVYTSQNQSPELREYRYEVQDFQENMQILLGKVTEECSKLLVLQTRLNKINEQQVDGVTFEFAEENVAEVEAGLLSGRSQSGLQGADVSHESKVSEYERQVQELQSLVAAGQLQLKETEANYRAEIQCLQERLQAVSEATVQPSLSMDSVVFKGSGAQKPVYCGSCLREQVDGTAEFSDGFEVRQETNMVKLMEKQYQERLEEEIAKVIVSMSIAFAQQTELSRLSEEKENVIQSEQAHALCSQNEHHLNDITSQCQVGLQTVEATGKNLKEEFKPLSKELGEYRKAVPLSNHDDLDDVLKSEEHGLTISEEIFSKDETFLVRNSSPDEVLVSNMDTSRQLILNEQLEDMRQELVRQYEEHQQATELLRQAHMQQMERQREDQEQLQEEIKRLNQQLTQRSSIDTEHVVSERERVLLEELEALKRLSLAGRKELCCELQHSSTQTQDGNDNQEVEEQTLKDKTLERKPEDIPLDINLSNERYALKKANNRLLKILLDVVKTTSAAEETIGRHVLGILDRSSKSQPATSLLWRSETEASATVCVQEECARAMDESVPSYPGSAIATHDSVWSKVTEEGAELSQRLVRSGFAGPVIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAVELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQELLCTNNRLQELESDQRRMEEERELLSRQREAMRADAGPVEQRPIAAAAGAAPGAEFLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAELIDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRLLPVSEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDVQERNEEIEKLECRVRELEQALLATADPFPKVEEQKRPGAVEVDPELSLEVQLQAERDATDRKQKEITNLEEQLEQFREELENKNEEVQELLMQLEIQKKESTTRLQELQQENRLFKEEIEKLGFTMKESDSLSTQDQPMLFGKFAQLIQEKEIEIDRLNEQFIKLQQQLKLTTDNKVIEEQKDQIRDLETQIECLMSEQELMKKQRAEEAEQLNGVIEKLQQELVSTEQKREGARALPEDEESFKHQLDRVTVEKLGLEKQVETTNQELTDLKNVLKEINFKMDHMTQALCNLNKELPNVPKESVHVTVHELGCDKLQPEGASAQDASQPLESQTSLMCLQESTKASQILEIKSLPLQGSGSTKDFELAQCHKQIDTIQEQDQSEIGMLQKKITNLQKILEKFSAALVSWVQMEAAQDRVQLYQEKQTQTVSSAPERTDTQNVNCLAENNLESHVPTLAVRPAELESRVAEVLSDIMSEKHMETVGKNASETEKEVVALQKLLEEAKKRLKEEREQSPRDRERTAQLTHAGGGSGFSGGLETFEAESATSELASYKERAEKLEEDLLVKESYITSLQKDLGQVKDQLTEAKEKLSHYLEKENGTGEQESRRVPIPESPSVEGGGGSGTMERTGKVSSSNQTPQILVRHAGVQIDLQSERSQEELRDTINQFTEKMERIQELHAAEILDMESRHILETESLKKEHSVAIQLLTKECETLKDMTQYLRCKKGSSISDLADSVAYQSREVYSSDSESDWGQSQGFDTATEGREEGETSDLFPKKIKGLVKAVHSEGMQVLSLSNPLCDDGEDRSVQQLSESWLKERQTYLNTISSLKDLISKMQVQRETEVYDSCQSHDSFSDWRGELLLACQRVFIKERSVLLATFQTELTSLSTRDADGVLNSLEQRIQEQGIEYQTAMDCLQKADRRSLLTEIEDLRAQINGRKMTLEREQEIEKPSQELLDCNLQQKQSHVLEMQLELGSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEAFRSEIKEKTDEIHFLSDTLAREQKKSLELQWALEKEKAKSGHHEEWEKEELEDLKFSLEDQKRKNTQLNLLLEQQKQLLNESQQKMESQKMLHDAQLSEEQGRNLGLQALLESEQVRVQEMKSTLDKERELYAQLQSRDDGGQPLPVLPSEDLLKELQKQLEEKHTRIVELLSETEKYKLDSLQTRQQMEKDREVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGKRLQGIMQEFQKQELEPEEKRGSRGLVYQNLNEPASWTFTDDRTRNWVLQQKMGETKDTNFTKLIEINGELDHNHDLEVIRQTLQHVASKLQHVAQKACNRLQFETASDDAFIWIQENIDGIILQLQKLTGQPGDEHSLAPPSSSCGSLTESLMRQNTELTRLINQLTEEKNTLRSIVVKLEELNRCHWHTGAGRDCCSRFSFIDPADIEAIIASEKEVWNREKLSLQKALKRAEAKVYKLKAELRNDALLRSLSPDSEHAALQKIYNKYLRASSFRKALIYQKKYLLLLLGGFQECEDATLGVLARMGGHPALKDPKTITSHPKGFTRFRSAVRVSIAISRMKFLVRRWQQVTSTSSININRDGFGLSPGIEKTDPFYHSSGGLELYGEPRHTTYRSRFDLDYPRSPLPLQNRYPGAPDLNSTSMASSQLHQYNPDKSLTDYVTRLEALKRRLGAIQSGSTTQFHFGMRR" }, "uniprot_id": "A0A0G2K548_RAT", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Rat", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", "type": [ "PubMed" ], "id": "22673903" } ], "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nat. Commun.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", "date": "2012" } ], "uniprot_ac": "A0A0G2K548", "site_annotation": [ { "end_pos": 1202, "annotation": "n_glycosylation_sequon", "start_pos": 1200 }, { "end_pos": 1519, "annotation": "n_glycosylation_sequon", "start_pos": 1517 }, { "end_pos": 1671, "annotation": "n_glycosylation_sequon", "start_pos": 1669 }, { "end_pos": 1799, "annotation": "n_glycosylation_sequon", "start_pos": 1797 }, { "end_pos": 237, "annotation": "n_glycosylation_sequon", "start_pos": 235 }, { "end_pos": 242, "annotation": "n_glycosylation_sequon", "start_pos": 240 }, { "end_pos": 2594, "annotation": "n_glycosylation_sequon", "start_pos": 2592 }, { "end_pos": 2708, "annotation": "n_glycosylation_sequon", "start_pos": 2706 }, { "end_pos": 2745, "annotation": "n_glycosylation_sequon", "start_pos": 2743 }, { "end_pos": 3216, "annotation": "n_glycosylation_sequon", "start_pos": 3214 }, { "end_pos": 3438, "annotation": "n_glycosylation_sequon", "start_pos": 3436 }, { "end_pos": 3800, "annotation": "n_glycosylation_sequon", "start_pos": 3798 }, { "end_pos": 897, "annotation": "n_glycosylation_sequon", "start_pos": 895 }, { "end_pos": 981, "annotation": "n_glycosylation_sequon", "start_pos": 979 }, { "end_pos": 985, "annotation": "n_glycosylation_sequon", "start_pos": 983 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548#A0A0G2K548-1", "isoform_ac": "A0A0G2K548-1", "locus": { "end_pos": 27195852, "strand": "+", "start_pos": 27331333, "chromosome": "4", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000090751", "id": "ENSRNOT00000090751", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000073290", "id": "ENSRNOP00000073290", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2K548-1|A0A0G2K548_RAT Isoform 1 of A-kinase-anchoring protein 9 OS=Rattus norvegicus OX=10116 GN=Akap9 PE=1 SV=1 CANONICAL=A0A0G2K548-1", "length": 3847, "sequence": "MEDEERQRKLAAGKAKLARFRQRKAQCDGDIPKKQKKKRTPSSKQDSSLHTDQQSAEICSESSQRADSAGSPDSSSAEKAKHGQVFAADPESEISTTADECSSEINGCNSVTKPGNPTDTLREEDFSIDDSYSEQGAQSSQTCLQMGENELAEKQHEVEELTQELEEMRASFGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARKEKDDTTIEFLELTEQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTLQQQLQDYQKKEEDVQAQISFLQEKIRMLEMEKDRKVESLNTKEIEEKQAIIEELNTRVIEEERKTAELENKVTTADELLGQLQGQVTEKDQEIKSLKLELVNSQQNERKCSEEIKELMRTVEELQKRNLKDSQLGTGTVRRVEQETQRKLSLLQAELDEMYGKQIVQMKQELMKQHMSQIEELKSQHKRDLENTLKSDASTTVSKEQVNLMSAAISELNVRLQDTHAQKEKLKGELGAALGEKSALQSQFEDLLEEVRFLREQVQKARQTIAEQENRLSDARKSLSTVEDLKAEIVAASESRKELEVKHEAEITNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEVEHRINVEKLKDNLGIHYKQQIDGLQNEMNRKMETMQCETDNLITRQNQLILENSKLRDLQEHLVNSKSEEMNLQINELQKEIEILRREEKEKGSLEQEVQGLQLKTEQLERQLKEKGDDLQEKCAQLDAENSVLKDEKKALEDMLKMYTPLDQEDPSTRKSEDPRWQKEVGMLRKENEDLQQQCLHLSEEIEKQKNTFAFAEKNFEVNYQELQREYTCLLKIRDDLEDTLAKQALQYESKLSALEEELHSQRGSPTTPPKGENSGFAANRTFPLEPLEVGEVVEKDTTELMEKLEVTRREKLELSEKVSGLSEQLKQTHGTIDSLSEEVRALKQEKEQLLLRCGELELLTNANGTENASVCPVQRSPYQAGPVMGTVRDSQGPISKVSEDLAEESKPMTEDKIPFKESGREPLLLPTRTKKPSRVTVEPCESEKLQQELYALKAEQDDLRLQMEAQRLCLFVVYSTHADQVRAYMEKEREEALCSLKDELVSAQQKKIDELHKIHQCQLQHVKVQETGNEPLQVLIERLQKAVSEKCFHISKTLNNVFDECYTPLKCEMNIEEKENSGVYTSQNQSPELREYRYEVQDFQENMQILLGKVTEECSKLLVLQTRLNKINEQQVDGVTFEFAEENVAEVEAGLLSGRSQSGLQGADVSHESKVSEYERQVQELQSLVAAGQLQLKETEANYRAEIQCLQERLQAVSEATVQPSLSMDSVVFKGSGAQKPVYCGSCLREQVDGTAEFSDGFEVRQETNMVKLMEKQYQERLEEEIAKVIVSMSIAFAQQTELSRLSEEKENVIQSEQAHALCSQNEHHLNDITSQCQVGLQTVEATGKNLKEEFKPLSKELGEYRKAVPLSNHDDLDDVLKSEEHGLTISEEIFSKDETFLVRNSSPDEVLVSNMDTSRQLILNEQLEDMRQELVRQYEEHQQATELLRQAHMQQMERQREDQEQLQEEIKRLNQQLTQRSSIDTEHVVSERERVLLEELEALKRLSLAGRKELCCELQHSSTQTQDGNDNQEVEEQTLKDKTLERKPEDIPLDINLSNERYALKKANNRLLKILLDVVKTTSAAEETIGRHVLGILDRSSKSQPATSLLWRSETEASATVCVQEECARAMDESVPSYPGSAIATHDSVWSKVTEEGAELSQRLVRSGFAGPVIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAVELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQELLCTNNRLQELESDQRRMEEERELLSRQREAMRADAGPVEQRPIAAAAGAAPGAEFLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAELIDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRLLPVSEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDVQERNEEIEKLECRVRELEQALLATADPFPKVEEQKRPGAVEVDPELSLEVQLQAERDATDRKQKEITNLEEQLEQFREELENKNEEVQELLMQLEIQKKESTTRLQELQQENRLFKEEIEKLGFTMKESDSLSTQDQPMLFGKFAQLIQEKEIEIDRLNEQFIKLQQQLKLTTDNKVIEEQKDQIRDLETQIECLMSEQELMKKQRAEEAEQLNGVIEKLQQELVSTEQKREGARALPEDEESFKHQLDRVTVEKLGLEKQVETTNQELTDLKNVLKEINFKMDHMTQALCNLNKELPNVPKESVHVTVHELGCDKLQPEGASAQDASQPLESQTSLMCLQESTKASQILEIKSLPLQGSGSTKDFELAQCHKQIDTIQEQDQSEIGMLQKKITNLQKILEKFSAALVSWVQMEAAQDRVQLYQEKQTQTVSSAPERTDTQNVNCLAENNLESHVPTLAVRPAELESRVAEVLSDIMSEKHMETVGKNASETEKEVVALQKLLEEAKKRLKEEREQSPRDRERTAQLTHAGGGSGFSGGLETFEAESATSELASYKERAEKLEEDLLVKESYITSLQKDLGQVKDQLTEAKEKLSHYLEKENGTGEQESRRVPIPESPSVEGGGGSGTMERTGKVSSSNQTPQILVRHAGVQIDLQSERSQEELRDTINQFTEKMERIQELHAAEILDMESRHILETESLKKEHSVAIQLLTKECETLKDMTQYLRCKKGSSISDLADSVAYQSREVYSSDSESDWGQSQGFDTATEGREEGETSDLFPKKIKGLVKAVHSEGMQVLSLSNPLCDDGEDRSVQQLSESWLKERQTYLNTISSLKDLISKMQVQRETEVYDSCQSHDSFSDWRGELLLACQRVFIKERSVLLATFQTELTSLSTRDADGVLNSLEQRIQEQGIEYQTAMDCLQKADRRSLLTEIEDLRAQINGRKMTLEREQEIEKPSQELLDCNLQQKQSHVLEMQLELGSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEAFRSEIKEKTDEIHFLSDTLAREQKKSLELQWALEKEKAKSGHHEEWEKEELEDLKFSLEDQKRKNTQLNLLLEQQKQLLNESQQKMESQKMLHDAQLSEEQGRNLGLQALLESEQVRVQEMKSTLDKERELYAQLQSRDDGGQPLPVLPSEDLLKELQKQLEEKHTRIVELLSETEKYKLDSLQTRQQMEKDREVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGKRLQGIMQEFQKQELEPEEKRGSRGLVYQNLNEPASWTFTDDRTRNWVLQQKMGETKDTNFTKLIEINGELDHNHDLEVIRQTLQHVASKLQHVAQKACNRLQFETASDDAFIWIQENIDGIILQLQKLTGQPGDEHSLAPPSSSCGSLTESLMRQNTELTRLINQLTEEKNTLRSIVVKLEELNRCHWHTGAGRDCCSRFSFIDPADIEAIIASEKEVWNREKLSLQKALKRAEAKVYKLKAELRNDALLRSLSPDSEHAALQKIYNKYLRASSFRKALIYQKKYLLLLLGGFQECEDATLGVLARMGGHPALKDPKTITSHPKGFTRFRSAVRVSIAISRMKFLVRRWQQVTSTSSININRDGFGLSPGIEKTDPFYHSSGGLELYGEPRHTTYRSRFDLDYPRSPLPLQNRYPGAPDLNSTSMASSQLHQYNPDKSLTDYVTRLEALKRRLGAIQSGSTTQFHFGMRR" } }, { "url": "https://www.uniprot.org/uniprot/A0A0G2K548#F1LPB4-1", "isoform_ac": "F1LPB4-1", "locus": { "end_pos": 27195852, "strand": "+", "start_pos": 27331333, "chromosome": "4", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000010118", "id": "ENSRNOT00000010118", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000010118", "id": "ENSRNOP00000010118", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F1LPB4-1|A0A0G2K548_RAT Computationally mapped isoform of A-kinase-anchoring protein 9 OS=Rattus norvegicus OX=10116 GN=Akap9 PE=1 SV=2 CANONICAL=A0A0G2K548-1", "length": 3771, "sequence": "MEDEERQRKLAAGKAKLARFRQRKAQCDGDIPKKQKKKRTPSSKQDSSLHTDQQSAEICSESSQRADSAGSPDSSSAEKAKHGQVFAADPESEISTTADECSSEEEDFSIDDSYSEQGAQSSQTCLQMGENELAEKQHEVEELTQELEEMRASFGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARKEKDDTTIEFLELTEQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTLQQQLQDYQKKEEDVQAQISFLQEKIRMLEMEKDRKVESLNTKEIEEKQAIIEELNTRVIEEERKTAELENKVTTADELLGQLQGQVTEKDQEIKSLKLELVNSQQNERKCSEEIKELMRTVEELQKRNLKDSQLGTGTVRRVEQETQRKLSLLQAELDEMYGKQIVQMKQELMKQHMSQIEELKSQHKRDLENTLKSDASTTVSKEQVNLMSAAISELNVRLQDTHAQKEKLKGELGAALGEKSALQSQFEDLLEEVRFLREQVQKARQTIAEQENRLSDARKSLSTVEDLKAEIVAASESRKELEVKHEAEITNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEVEHRINVEKLKDNLGIHYKQQIDGLQNEMNRKMETMQCETDNLITRQNQLILENSKLRDLQEHLVNSKSEEMNLQINELQKEIEILRREEKEKGSLEQEVQGLQLKTEQLERQLKEKGDDLQEKCAQLDAENSVLKDEKKALEDMLKMYTPLDQEDPSTRKSEDPRWQKEVGMLRKENEDLQQQCLHLSEEIEKQKNTFAFAEKNFEVNYQELQREYTCLLKIRDDLEDTLAKQALQYESKLSALEEELHSQRGSPTTPPKGENSGFAANRTFPLEPLEVGEVVEKDTTELMEKLEVTRREKLELSEKVSGLSEQLKQTHGTIDSLSEEVRALKQEKEQLLLRCGELELLTNANGTENASVCPVQRSPYQAGPVMGTVRDSQGPISKVSEDLAEESKPMTEDKIPFKESGREPLLLPTRTKKPSRVTVEPCESEKLQQELYALKAEQDDLRLQMEAQRLCLFVVYSTHADQVRAYMEKEREEALCSLKDELVSAQQKKIDELHKIHQCQLQHVKVQETGNEPLQVLIERLQKAVSEKCFHISKTLNNVFDECYTPLKCEMNIEEKENSGVYTSQNQSPELREYRYEVQDFQENMQILLGKVTEECSKLLVLQTRLNKINEQQVDGVTFEFAEENVAEVEAGLLSGRSQSGLQGADVSHESKVSEYERQVQELQSLVAAGQLQLKETEANYRAEIQCLQERLQAVSEATVQPSLSMDSVVFKGSGAQKPVYCGSCLREQVDGTAEFSDGFEVRQETNMVKLMEKQYQERLEEEIAKVIVSMSIAFAQQTELSRLSEEKENVIQSEQAHALCSQNEHHLNDITSQCQVGLQTVEATGKNLKEEFKPLSKELGEYRKAVPLSNHDDLDDVLKSEEHGLTISEEIFSKDETFLVRNSSPDEVLVSNMDTSRQLILNEQLEDMRQELVRQYEEHQQATELLRQAHMQQMERQREDQEQLQEEIKRLNQQLTQRSSIDTEHVVSERERVLLEELEALKRLSLAGRKELCCELQHSSTQTQDGNDNQEVEEQTLKDKTLERKPEDIPLDINLSNERYALKKANNRLLKILLDVVKTTSAAEETIGRHVLGILDRSSKSQPATSLLWRSETEASATVCVQEECARAMDESVPSYPGSAIATHDSVWSKVTEEGAELSQRLVRSGFAGPVIDPENEELMLNISSRLQAAVEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAVELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQELLCTNNRLQELESDQRRMEEERELLSRQREAMRADAGPVEQQFLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAELIDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKAVPRLLPVSEHQTREVEQLTNHLKEKTDKCSELLLSKEQLQRDVQERNEEIEKLECRVRELEQALLATADPFPKVEEQKRPGAVEVDPELSLEVQLQAERDATDRKQKEITNLEEQLEQFREELENKNEEVQELLMQLEIQKKESTTRLQELQQENRLFKEEIEKLGFTMKESDSLSTQDQPMLFGKFAQLIQEKEIEIDRLNEQFIKLQQQLKLTTDNKVIEEQKDQIRDLETQIECLMSEQELMKKQRAEEAEQLNGVIEKLQQELVSTEQKREGARALPEDEESFKHQLDRVTVEKLGLEKQVETTNQELTDLKNVLKEINFKMDHMTQALCNLNKELPNVPKESVHVTVHELGCDKLQPEGASAQDASQPLESQTSLMCLQESTKASQILEIKSLPLQGSGSTKDFELAQCHKQIDTIQEQDQSEIGMLQKKITNLQKILEKFSAALVSWVQMEAAQDRVQLYQEKQTQTVSSAPERTDTQNVNCLAENNLESHVPTLAVRPAELESRVAEVLSDIMSEKHMETVGKNASETEKEVVALQKLLEEAKKRLKEEREQSPRDREVKESYITSLQKDLGQVKDQLTEAKEKLSHYLEKENGTGEQESRRVPIPESPSVEGGGGSGTMERTGKVSSSNQTPQILVRHAGVQIDLQSERSQEELRDTINQFTEKMERIQELHAAEILDMESRHILETESLKKEHSVAIQLLTKECETLKDMTQYLRCKKGSSISDLADSVAYQSREVYSSDSESDWGQSQGFDTATEGREEGETSDLFPKKIKGLVKAVHSEGMQVLSLSNPLCDDGEDRSVQQLSESWLKERQTYLNTISSLKDLISKMQVQRETEVYDSCQSHDSFSDWRGELLLACQRVFIKERSVLLATFQTELTSLSTRDADGVLNSLEQRIQEQGIEYQTAMDCLQKADRRSLLTEIEDLRAQINGRKMTLEREQEIEKPSQELLDCNLQQKQSHVLEMQLELGSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEAFRSEIKEKTDEIHFLSDTLAREQKKSLELQWALEKEKAKSGHHEEWEKEELEDLKFSLEDQKRKNTQLNLLLEQQKQLLNESQQKMESQKMLHDAQLSEEQGRNLGLQALLESEQVRVQEMKSTLDKERELYAQLQSRDDGGQPLPVLPSEDLLKELQKQLEEKHTRIVELLSETEKYKLDSLQTRQQMEKDREVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGKRLQGIMQEFQKQELEPEEKRGSRGLVYQNLNEPASWTFTDDRTRNWVLQQKMGETKDTNFTKLIEINGELDHNHDLEVIRQTLQHVASKLQHVAQKACNRLQFETASDDAFIWIQENIDGIILQLQKLTGQPGDEHSLAPPSSSCGSLTESLMRQNTELTRLINQLTEEKNTLRSIVVKLEELNRCHWHTGAGRDCCSRFSFIDPADIEAIIASEKEVWNREKLSLQKALKRAEAKVYKLKAELRNDALLRSLSPDSEHAALQKIYNKYLRASSFRKALIYQKKYLLLLLGGFQECEDATLGVLARMGGHPALKDPKTITSHPKGFTRFRSAVRVSIAISRMKFLVRRWQQVTSTSSININRDGFGLSPGIEKTDPFYHSSGGLELYGEPRHTTYRSRFDLDYPRSPLPLQNRYPGAPDLNSTSMASSQLHQYNPDKSLTDYVTRLEALKRRLGAIQSGSTTQFHFGMRR" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2565942", "resource": "Reactome", "id": "R-RNO-2565942", "name": "Regulation of PLK1 Activity at G2/M Transition" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-380259", "resource": "Reactome", "id": "R-RNO-380259", "name": "Loss of Nlp from mitotic centrosomes" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-380270", "resource": "Reactome", "id": "R-RNO-380270", "name": "Recruitment of mitotic centrosome proteins and complexes" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-380284", "resource": "Reactome", "id": "R-RNO-380284", "name": "Loss of proteins required for interphase microtubule organization from the centrosome" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-380320", "resource": "Reactome", "id": "R-RNO-380320", "name": "Recruitment of NuMA to mitotic centrosomes" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5576890", "resource": "Reactome", "id": "R-RNO-5576890", "name": "Phase 3 - rapid repolarisation" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5576893", "resource": "Reactome", "id": "R-RNO-5576893", "name": "Phase 2 - plateau phase" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-5620912", "resource": "Reactome", "id": "R-RNO-5620912", "name": "Anchoring of the basal body to the plasma membrane" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-8854518", "resource": "Reactome", "id": "R-RNO-8854518", "name": "AURKA Activation by TPX2" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "Q70FJ1-1", "protein_name": "A-kinase anchor protein 9", "sequence": { "length": 3797, "sequence": "MEDEERQRKLAAGKAKLARFRQRKAQYDGDIPKKQKKKRTSSSKHDSSLHTDQQSGELCSESSQRVDLAGNPDCSGPERKHGQVFSAEPESEISTTADECSSEINGCNSVMKPRKPTDPLREEEFSLDDSSSEQGAQSSQTCLQMVEKELAEKQHDIEELTQELEEMRASFGTEGLKQLQEFEAAIKQRDGIITQLTANLQQARREKDDTMVEFLELTEQSQKLQIQFQHLQANETLQNSTLSRTATDLLQAKRQIFTQQQQLQDYQKKEEDLQAQISFLQEKLRAFEMEKDRKIENLNAKEIQEKQALIDELNTRVVEEEKKTVELKNKVTTADELLGGLHEQLTQRNQEIQSLKLELGNSQQNERKCSEEIKELMRTVEELQKRNLKDSWLETSAVRRVEQETQRKLSHLQAELDEMYGKQIVQMKQELINQHMSQIEELKSQHKREMENTLKSDTNAAISKEQVNLMNAAINELNVRLQETHAQKEELKGELGVVLGEKSALQSQSNDLLEEVRFLREQVQKARQTIAEQENRLSEARKSLSTVEDLKAEIVAASESRKELELKHEAEITNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQPLFSHEEELSKLKEDLEVEHRINIEKLKDNLGIHYKQQIDGLQNEMNRKMESMQCETDNLITQQNQLILENSKLRDLQECLVNSKSEEMNLQINELQKEIEILKQEEKEKGTLEQEVQELQLKTEQLEKQLKEKEDDLQEKCAQLDAENNILKEEKRVLEDKLKMYSPSEQEERSIAVDPSTSKLADSRWQKEVAMLRKETEDLQQQCLYLNEEIEKQRNTFAFAEKNFEVNYQELQREYTCLLKIRDDLEATQTKQALEYESKLRALEEELLSKRGNPXAPKGKSSGIFPSETLEIGEVVEKDTTELMEKLEVTKREKLELSEKVSGLSEQLKQTHCTINSLSAEXRALKQEKEQLLLRCGELELLANPSGTENAAVCPVQMSSYQAGLVMGKVGDSGGSISKISKDLAEESKPMIEDKIPFKESGREQLLLPTRAQEPSHATVEPCESEKLQQELHALKAEQDDLRLQMEAQRICLFVVYSTHADQVRAHMEKEREEALCSLKDELISAQQKKIDELHKMHQCQLQNVKIQETGDEPLQVLIERLQKAVSEKCFHISKTLNNVFDECYTPLKCEMNIEEKENSGVYTSQNQSPELQEYRYEVQDFQESMQVLLGKVTEECRKLSGLQTRLGKIHEQQTDGVALEFAEQNAAEEEAGLLSGCSQSALQSTDVSLESKVSSLPASEKNRECERQVQELQSPVAAGQLQLTETEASHRAEIECLQQRLEAASEAPVQPSLSIDSVVFKGSGAQKPVYCGSCLREYVDGTAKFSDRFEVRQETNMVNLMEKQYQERLEEEIAKVIVSMSIAFAQQTELSRLSEGKENTIQSEQAHTLCSQNKHQLNDITSQSQVGLQTFEATDKBFKEEFKPLSKELGEYRKAVPLSSHDDLDDILKSEEHGLAISEEIFSKDETFIVRKSMHDEVLVSSMDTSRQLILNEQLEDMRQELVRQYEEHQQATEMLRQAHMQQMERQREDQEQLQEEIKRLNEQLTQKSSIDTEHVVSERERVLLEELEALKQLPLAGRKELCCELRHSSTQTQDGHDDQEVEEQTLKDKTLERSPEDALLDRNLSNERYALKKANNRLLKILLEVVKTTSAAEETIGRHVLGILDRSSKGQTASSLLWRSEADASATTCAPEDCARAMDESIPSYPGTAIATHDSIWSKVTEEGAELSQRLVRSGFAGPVIDPENEELMLNISSRLQAAVEKLLEAISETNTQLEHAKVTQTELMRESFRQKQEATESLHCLEELRERLQEESRAREQLAEELNKAESVIDGYSDEKTLFERQIQEKTDIIEHLEQEVLCMNNRLQELESDQRRVEEERQLLCRQREAMRAEAGPVEQQFLQETEKLMKEKLEVQCQAEKVRGDLQKQVKALEIDVEEQVSRFIELEQEKNAELTDLRQQSQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEHQLKAAPRIQPVSEHQAREVEQLTNHLKEKTDRCSELLLSKEQLQRDIQERNEEIEKLECRVRELEQALLASAEPFPKVEDQKRSGAVAADPELSLEVQLQAERDATDRKQKEITNLEEQLEQFREELENKNDEVQELLMQLEIQRKESTTRLQELQQENRLFKDEIEKLGFAMKESDSVSTRDQPMLFGKFAQLIQEKEIEIDRLNEQFIKLQQQLKLTTDNKVIEEQKEQIQDLETQIERLMSEREHEKKQREEEVEQLTGVVEKLQQEVVSTEQQREGARTLPEDEESFKHQLDKVTAEKLVLEQQVETTNQVMTHMNNVLKEINFKMDQITQSLCNLNKECASNEELPSLPKESVHMTVHELGSDNLQPEDAPAQDVTKPLEKQTSLTRLQESPEASRTQEIESLASSVGAKDVELTQCREQTETIQEQAQSETDRLQKKLTDLQRSLEKFAAALVSQVQMEAAQEYVPFHQEKQPVSSAPGSTDIQNANGLTGASTESLIPTVTLRLAEVESRVAEVHSGTMSEKLVGIVGGNASETEKRVIELQKLLEEAEERPEEGGEQSSRDGEVRESYMTSLQKDLGQVKDPLTEAKEKLSYSLEKEKRTGEQESREAPIPEPPSVEVGGCSGLTERTDKVSSSGNQTLQILLRDAAIQTDLQSESSQEEVRDTINQLTKKMEHIQELHAAEILDMESRHILETESLKKEHYVAIQLLTKECETLKEMTQCLRCKEGSSIPELADSVAYQSREVYSSDSESDWGQSQGFDTAIEGREEGETSADLFPKKIKGLVKAVHSEGMQVLSLSSPLCDDGEDRSIQQLSESWLKERQAYLNTISSLKDLISKMQVRRETEVYDRCHLSDWRGELLLACQRVFIKERSVLLATFQTELTSLSTRDVDGLLNSLEQRIQEQGIEYHTAMDCLQKADRRSLLAEIEDLRAQINGGKMTLEREQGTEKSSQELLDCSMQQKQSLEMQLELSSLRDRAAELQEQLSSEKMVVAELKSELAQAKLELGTTLKAQHKRLKELEAFRSEVKEKTDEIHFLSDTLAREQKNSLELQWALEKEKARSGHHEEREKEELEDLKFSLEDQKRRNTQLNLLLEQQKQLLNESQQKIESQKMLHDAQLSEEQGRNLGLQALLESEQVRIQEMKSTLDKERELYAQLQSREDGGQPPPALPSEDLLKELQKQLEEKHSRIVELLSETEKYKLDSLQTRQQMEKDRQVHQKTLQTEQEANTQGQKKMQELQSKVEELQRQLQEKRQQVYKLDLEGKRLQGLMQEFQKQELEPEEKPGSRGLVDQNLNEPATWNFTDDRTRNWVLQQKMGEAKDRNFTKLIEINGGELDHNHDLEMIRQTLQHVASKLQHVAQKACSRLQFETAGDDAFIWIQENIDGIILQLQKLTGQPGDEHSLGPPSSSCGSLTESLMRQNTELTRLINQLTEEKNTLRSIVIKLEELNRCYWHTGASRDCCSRFSFIDPADIEAIIASEKEVWNREKLSLQKALKRAEAKVYKLKAELRNDALLRNLGPDTDHAALQKIYNKYLRASSFRKALIYQKKYLLLLLGGFQECEDVTLGVLARMGGHLALKDSKTITNHPKAFSRFRSAVRVSIAISRMKFLVRRWQQVTSTSSININRDGFGLSPGIEKTDPFYHSPGGLELYGEPRHTMYRSRFDLDYPRSLLPLQNRYPGTPGDLNSISMASSQLHQYNPDKSLTDYVTRLEALRRRLGAIQSGSTTQFHFGMRR" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/134583", "id": "134583", "database": "MGI" } ], "common_name": "Mouse", "organism": "Mus musculus", "gene_name": "Akap9", "tax_id": 10090 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017447936.1", "ac": "XP_017447936.1", "name": "A-kinase anchor protein 9 isoform X4", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034237", "pmid": "10618500", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "protein kinase A regulatory subunit binding", "id": "GO:0034237" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060090", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "molecular adaptor activity", "id": "GO:0060090" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015459", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "potassium channel regulator activity", "id": "GO:0015459" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "ion channel binding", "id": "GO:0044325" } ], "total": 4, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "pmid": "10618500", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "neuronal cell body", "id": "GO:0043025" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044307", "pmid": "10618500", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "dendritic branch", "id": "GO:0044307" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097060", "pmid": "10618500", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "synaptic membrane", "id": "GO:0097060" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "glutamatergic synapse", "id": "GO:0098978" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "Golgi apparatus", "id": "GO:0005794" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "centrosome", "id": "GO:0005813" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "voltage-gated potassium channel complex", "id": "GO:0008076" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005795", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K548", "id": "A0A0G2K548", "database": "UniProtKB" } ], "name": "Golgi stack", "id": "GO:0005795" }, { "url": 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