{
    "uniprot_canonical_ac": "A0A0G2K2P3-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A0A0G2K2P3-1|A0A0G2K2P3_RAT Isoform 1 of TNF alpha-induced protein 8  OS=Rattus norvegicus OX=10116 GN=Tnfaip8 PE=4 SV=1 CANONICAL=A0A0G2K2P3-1", 
        "length": 192, 
        "sequence": "MPKLVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEKVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKRKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHDIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI"
    }, 
    "uniprot_id": "A0A0G2K2P3_RAT", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Rat", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3", 
                    "id": "A0A0G2K2P3", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "publication": [], 
    "uniprot_ac": "A0A0G2K2P3", 
    "site_annotation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3#A0A0G2K2P3-1", 
            "isoform_ac": "A0A0G2K2P3-1", 
            "locus": {
                "end_pos": 44716424, 
                "strand": "-", 
                "start_pos": 44778806, 
                "chromosome": "18", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000086431", 
                        "id": "ENSRNOT00000086431", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000072322", 
                        "id": "ENSRNOP00000072322", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A0G2K2P3-1|A0A0G2K2P3_RAT Isoform 1 of TNF alpha-induced protein 8  OS=Rattus norvegicus OX=10116 GN=Tnfaip8 PE=4 SV=1 CANONICAL=A0A0G2K2P3-1", 
                "length": 192, 
                "sequence": "MPKLVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEKVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKRKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHDIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3#D4A9G3-1", 
            "isoform_ac": "D4A9G3-1", 
            "locus": {
                "end_pos": 44778309, 
                "strand": "-", 
                "start_pos": 44778806, 
                "chromosome": "18", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000021972", 
                        "id": "ENSRNOT00000021972", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000021972", 
                        "id": "ENSRNOP00000021972", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|D4A9G3-1|A0A0G2K2P3_RAT Computationally mapped isoform of TNF alpha-induced protein 8  OS=Rattus norvegicus OX=10116 GN=Tnfaip8 PE=4 SV=1 CANONICAL=A0A0G2K2P3-1", 
                "length": 166, 
                "sequence": "MVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEKVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKRKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHDIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-1483255", 
            "resource": "Reactome", 
            "id": "R-RNO-1483255", 
            "name": "PI Metabolism"
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "O95379-1", 
            "protein_name": "Tumor necrosis factor alpha-induced protein 8", 
            "sequence": {
                "length": 198, 
                "sequence": "MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIQRHLTAKSHGRVNNVFDHFSDCEFLAALYNPFGNFKPHLQKLCDGINKMLDEENI"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/8649", 
                    "id": "8649", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "gene_name": "TNFAIP8", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "Q921Z5-1", 
            "protein_name": "Tumor necrosis factor alpha-induced protein 8", 
            "sequence": {
                "length": 198, 
                "sequence": "MLSEAEEPREVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAERVIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHEIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/8649", 
                    "id": "8649", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "gene_name": "Tnfaip8", 
            "tax_id": 10090
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006254770.1", 
        "ac": "XP_006254770.1", 
        "name": "tumor necrosis factor alpha-induced protein 8 isoform X2", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043027", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3", 
                                "id": "A0A0G2K2P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cysteine-type endopeptidase inhibitor activity involved in apoptotic process", 
                        "id": "GO:0043027"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3", 
                                "id": "A0A0G2K2P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "nucleoplasm", 
                        "id": "GO:0005654"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3", 
                                "id": "A0A0G2K2P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }
                ], 
                "total": 2, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3", 
                                "id": "A0A0G2K2P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of apoptotic process", 
                        "id": "GO:0043065"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050830", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3", 
                                "id": "A0A0G2K2P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "defense response to Gram-positive bacterium", 
                        "id": "GO:0050830"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032611", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3", 
                                "id": "A0A0G2K2P3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "interleukin-1 beta production", 
                        "id": "GO:0032611"
                    }
                ], 
                "total": 3, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0A0G2K2P3", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Tnfaip8"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Tnfaip8"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000026136", 
            "id": "ENSRNOG00000026136", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/307428", 
            "id": "307428", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008477", 
            "id": "IPR008477", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038355", 
            "id": "IPR038355", 
            "database": "InterPro"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/LYNPFGT/", 
            "id": "LYNPFGT", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=1284744at2759", 
            "id": "1284744at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12757", 
            "id": "PTHR12757", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF05527", 
            "id": "PF05527", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-1483255", 
            "id": "R-RNO-1483255", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006254770.1", 
            "id": "XP_006254770.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1305908", 
            "id": "1305908", 
            "database": "RGD"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3", 
            "id": "A0A0G2K2P3", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 22244.0, 
        "chemical_mass": 22244.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3", 
            "name": "Tnfaip8", 
            "locus": {
                "end_pos": 44779914, 
                "strand": "+", 
                "start_pos": 44716226, 
                "chromosome": "18", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000026136", 
                        "id": "ENSRNOG00000026136", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A0G2K2P3#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "TNF alpha-induced protein 8"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0A0G2K2P3", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "tumor necrosis factor alpha-induced protein 8 isoform X2"
        }
    ]
}