{ "uniprot_canonical_ac": "A0A0G2K178-1", "ptm_annotation": [], "sequence": { "header": "tr|A0A0G2K178-1|A0A0G2K178_RAT Isoform 1 of Bromodomain adjacent to zinc finger domain, 2A OS=Rattus norvegicus OX=10116 GN=Baz2a PE=1 SV=1 CANONICAL=A0A0G2K178-1", "length": 1685, "sequence": "MEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLSTVSHTTTSGILNSAPHSSSTSHLHHPNVAYDCLWNYSQYPSANPGNNLKDPPLLSQYPGGQYPLNGILGGSQQPSSPSHNTNLRAGSQEFWANGTQSPVGLNFDSQELYDSFPDQNFEVMPNGPPSFFTSPQTSPMLGSSIQTFAPSQGVSSDLHPDEAAEKELTSVVAENGTGLVGSLELEEEQPELKMCGYNGSVSSVESLHQEVSVLVPDPTVSCLDDPSHLPEQLEDTPILSEDSLEPFDSLAAEPVSEGLYSIDDTELMGTEDKLPLEDNPVISALDCPALSNANAFSLLAEDSQTSASIFVSPTSPPVLGESVLQDNSFGLNSCSDSEQEEMETQSSNFQRSLTEPAPDQPPSIQLHPAASPTASPVASLAASAEISPAASPVASSPIPPEVFPAVSPASSPALPAISLEASMAAPVTSPPGSPEPSAPAALQTVSTASKDGSSAPGACAGQEEMAGEAVAGSGIGDVLKRHIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRNVVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAXEIPSXIXAITGRRXRPRNSEKSKDXXXXXXXXXXXXXXXXXXXXXXXXXXXDNRLPKKLKXKETLSEEDKAKMTKSKKKVRQKVQRGESQPPVQGQARNKRKQDTKNSKPKDTKRKFKAEKEKMKTKQEKLKEKVKREKKEKVKVKGKEEPRARPSCRATQRRLEERQRQQVILEEMKKPTEDMCLADHQPLPDFTRIPGLTLSSRAFSDCLTIVEFLHSFGKVLGFDLTKDVPSLGVLQEGLLCQGDSLDKVQDLLVRLLKAALHDPGLPSYCQSLKILGEKVSEIPLTRDNVSEVLRCFLMAYRVEPSFCDSLRTQPFQAQPPQQKASVLAFLVHELNGSTIVINEIDKTLENMSSYRKNKWIVEGRLRRLKTALAKRTGRPEVMMEGVDDSLGRRRSSRIMEETSGIEEEEEEENTVAVHGRRGRRDGEVDVAASSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRFRRHYWVLPCLAGIFVEGSEGSAVTEDGIKQETESLMEAVTSTPSSAQVSVKREPTGSTTSTSPARSRGRPRKPKPGSLQPQHLKSTIREHDSEQAQSQAHPRAQPQPQPQPQPQPQPQTPIQPHLQSSNGFLEPEGSPFSLGQSQHDLSQSAFLSWLSQTQSHNSLLSSSVLTPDSSPGKLDSAPSQSLEEPEPDETQPCPGPQGPWFNFSAQIPCDAAPTPPPAVSEDQPTPSLQLPASSKPMNTPGAANPCSPVQLSFTHLPGGGPKRLSGDSEEIPQSPTGLGQPKRRGRPPSKFFKQVEQHYLTQLTAQPIPPDMCSGWWWIRDPETLDVLLKALHPRGIREKALHKHLSKHKDFLQEVCLQPLTDPIFEPSQLPALEEGIMSWSPKEKTFETDLAVLQWVEELERRVVLSDLQIRGWTCPSPDSTREDLTYCEHLPDSQEDIPWRGRGREGAVPQRQNTNPLDLAVMRLAVLEQNVERRYLREPLWAAHEVVVEKALLSTPSGEPDSATTEISYEITPRVRVWRQTLERCRSAAQVCLCVGQLERSIAWEKSVNKVDLSGSCRKGCTMTSFSC" }, "uniprot_id": "A0A0G2K178_RAT", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Rat", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/22673903", "type": [ "PubMed" ], "id": "22673903" } ], "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nat. Commun.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "authors": "Olsen J.V., Lage K., Secher A., Dmytriyev A., Lundby A., Lundby C., Nordsborg N.B.", "date": "2012" } ], "uniprot_ac": "A0A0G2K178", "site_annotation": [ { "end_pos": 1318, "annotation": "n_glycosylation_sequon", "start_pos": 1316 }, { "end_pos": 152, "annotation": "n_glycosylation_sequon", "start_pos": 150 }, { "end_pos": 230, "annotation": "n_glycosylation_sequon", "start_pos": 228 }, { "end_pos": 253, "annotation": "n_glycosylation_sequon", "start_pos": 251 }, { "end_pos": 36, "annotation": "n_glycosylation_sequon", "start_pos": 34 }, { "end_pos": 10, "annotation": "n_glycosylation_sequon", "start_pos": 8 }, { "end_pos": 924, "annotation": "n_glycosylation_sequon", "start_pos": 922 }, { "end_pos": 94, "annotation": "n_glycosylation_sequon", "start_pos": 92 }, { "end_pos": 971, "annotation": "n_glycosylation_sequon", "start_pos": 969 }, { "end_pos": 986, "annotation": "n_glycosylation_sequon", "start_pos": 984 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178#A0A0G2K178-1", "isoform_ac": "A0A0G2K178-1", "locus": { "end_pos": 2529077, "strand": "-", "start_pos": 2547062, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000079383", "id": "ENSRNOT00000079383", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000071731", "id": "ENSRNOP00000071731", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2K178-1|A0A0G2K178_RAT Isoform 1 of Bromodomain adjacent to zinc finger domain, 2A OS=Rattus norvegicus OX=10116 GN=Baz2a PE=1 SV=1 CANONICAL=A0A0G2K178-1", "length": 1685, "sequence": "MEANDHFNFTGLPPAPAASGLKPSPSSGEGLYTNGSPMNFPQQGKSLNGDVNVNGLSTVSHTTTSGILNSAPHSSSTSHLHHPNVAYDCLWNYSQYPSANPGNNLKDPPLLSQYPGGQYPLNGILGGSQQPSSPSHNTNLRAGSQEFWANGTQSPVGLNFDSQELYDSFPDQNFEVMPNGPPSFFTSPQTSPMLGSSIQTFAPSQGVSSDLHPDEAAEKELTSVVAENGTGLVGSLELEEEQPELKMCGYNGSVSSVESLHQEVSVLVPDPTVSCLDDPSHLPEQLEDTPILSEDSLEPFDSLAAEPVSEGLYSIDDTELMGTEDKLPLEDNPVISALDCPALSNANAFSLLAEDSQTSASIFVSPTSPPVLGESVLQDNSFGLNSCSDSEQEEMETQSSNFQRSLTEPAPDQPPSIQLHPAASPTASPVASLAASAEISPAASPVASSPIPPEVFPAVSPASSPALPAISLEASMAAPVTSPPGSPEPSAPAALQTVSTASKDGSSAPGACAGQEEMAGEAVAGSGIGDVLKRHIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFPEVIKYLSRNVVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAXEIPSXIXAITGRRXRPRNSEKSKDXXXXXXXXXXXXXXXXXXXXXXXXXXXDNRLPKKLKXKETLSEEDKAKMTKSKKKVRQKVQRGESQPPVQGQARNKRKQDTKNSKPKDTKRKFKAEKEKMKTKQEKLKEKVKREKKEKVKVKGKEEPRARPSCRATQRRLEERQRQQVILEEMKKPTEDMCLADHQPLPDFTRIPGLTLSSRAFSDCLTIVEFLHSFGKVLGFDLTKDVPSLGVLQEGLLCQGDSLDKVQDLLVRLLKAALHDPGLPSYCQSLKILGEKVSEIPLTRDNVSEVLRCFLMAYRVEPSFCDSLRTQPFQAQPPQQKASVLAFLVHELNGSTIVINEIDKTLENMSSYRKNKWIVEGRLRRLKTALAKRTGRPEVMMEGVDDSLGRRRSSRIMEETSGIEEEEEEENTVAVHGRRGRRDGEVDVAASSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRFRRHYWVLPCLAGIFVEGSEGSAVTEDGIKQETESLMEAVTSTPSSAQVSVKREPTGSTTSTSPARSRGRPRKPKPGSLQPQHLKSTIREHDSEQAQSQAHPRAQPQPQPQPQPQPQPQTPIQPHLQSSNGFLEPEGSPFSLGQSQHDLSQSAFLSWLSQTQSHNSLLSSSVLTPDSSPGKLDSAPSQSLEEPEPDETQPCPGPQGPWFNFSAQIPCDAAPTPPPAVSEDQPTPSLQLPASSKPMNTPGAANPCSPVQLSFTHLPGGGPKRLSGDSEEIPQSPTGLGQPKRRGRPPSKFFKQVEQHYLTQLTAQPIPPDMCSGWWWIRDPETLDVLLKALHPRGIREKALHKHLSKHKDFLQEVCLQPLTDPIFEPSQLPALEEGIMSWSPKEKTFETDLAVLQWVEELERRVVLSDLQIRGWTCPSPDSTREDLTYCEHLPDSQEDIPWRGRGREGAVPQRQNTNPLDLAVMRLAVLEQNVERRYLREPLWAAHEVVVEKALLSTPSGEPDSATTEISYEITPRVRVWRQTLERCRSAAQVCLCVGQLERSIAWEKSVNKVDLSGSCRKGCTMTSFSC" } } ], "pathway": [], "function": [], "orthologs": [], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [], "refseq": {}, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "DNA binding", "id": "GO:0003677" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "RNA binding", "id": "GO:0003723" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "histone binding", "id": "GO:0042393" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070577", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "lysine-acetylated histone binding", "id": "GO:0070577" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001164", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "RNA polymerase I core promoter sequence-specific DNA binding", "id": "GO:0001164" } ], "total": 5, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "nucleolus", "id": "GO:0005730" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "cytosol", "id": "GO:0005829" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "nuclear speck", "id": "GO:0016607" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005677", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "chromatin silencing complex", "id": "GO:0005677" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033553", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "rDNA heterochromatin", "id": "GO:0033553" } ], "total": 5, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051567", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "histone H3-K9 methylation", "id": "GO:0051567" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006338", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "chromatin remodeling", "id": "GO:0006338" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000183", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "rDNA heterochromatin assembly", "id": "GO:0000183" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006306", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "DNA methylation", "id": "GO:0006306" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016575", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "histone deacetylation", "id": "GO:0016575" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016479", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "negative regulation of transcription by RNA polymerase I", "id": "GO:0016479" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070933", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "histone H4 deacetylation", "id": "GO:0070933" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "heterochromatin assembly", "id": "GO:0031507" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034770", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "name": "histone H4-K20 methylation", "id": "GO:0034770" } ], "total": 9, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "type": "recommended", "resource": "UniProtKB", "name": "Baz2a" } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000053881", "id": "ENSRNOG00000053881", "database": "Bgee" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001739", "id": "IPR001739", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR016177", "id": "IPR016177", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR018501", "id": "IPR018501", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR028940", "id": "IPR028940", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR028941", "id": "IPR028941", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR028942", "id": "IPR028942", "database": "InterPro" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45915:SF5", "id": "PTHR45915:SF5", "database": "PANTHER" }, { "url": "http://pfam.xfam.org/family/PF01429", "id": "PF01429", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF02791", "id": "PF02791", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF15612", "id": "PF15612", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF15613", "id": "PF15613", "database": "Pfam" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1305037", "id": "1305037", "database": "RGD" }, { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "id": "A0A0G2K178", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 185284.0, "chemical_mass": 185284.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178", "name": "Baz2a", "locus": { "end_pos": 2547062, "strand": "+", "start_pos": 2529077, "chromosome": "7", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000053881", "id": "ENSRNOG00000053881", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A0A0G2K178#names_and_taxonomy", "type": "synonym", "resource": "UniProtKB", "name": "Bromodomain adjacent to zinc finger domain, 2A" } ] }