{
    "uniprot_canonical_ac": "A0A096MK02-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A0A096MK02-1|A0A096MK02_RAT Isoform 1 of Opticin  OS=Rattus norvegicus OX=10116 GN=Optc PE=4 SV=1 CANONICAL=A0A096MK02-1", 
        "length": 405, 
        "sequence": "MGNLIRHMDPWANYLSSPWPINEGVSSCPLVWQAVIIPIRVFVSLEAAGPDGTKTSKRMYVEWIQPFPLLPFPQNLMKFLTFLSLLTLVLQEAGTASLLGEREREEKSPEEADTYASLHVGNYSLSLEDYSEVIDLSSYEELADYGDQIPEAKTSSPTLPTRTSPTSPVVPRTLPSRLTMAGPTTTGLLNSQSSHGLPTCLVCVCLGSSVYCDDANLENIPPLPQMTTYLYARFNHISHIQAGDFKGMTKLRRIDLSSNSISSIHNDALRLLPALQDLILPENQLAALPVLPSGLEFLDVRLNRLQSSGIQPEAFVTLEKLQFLYLADNLLDSIPGPLPLSLRSLHLQNNKIEAMESDTFCDTTEHRHERRRQLEDIRLDGNPINLSLFPEAYFCLPRLPVGRFT"
    }, 
    "uniprot_id": "A0A096MK02_RAT", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Rat", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A096MK02", 
                    "id": "A0A096MK02", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "publication": [], 
    "uniprot_ac": "A0A096MK02", 
    "site_annotation": [
        {
            "end_pos": 124, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 122
        }, 
        {
            "end_pos": 387, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 385
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A096MK02#A0A096MJH6-1", 
            "isoform_ac": "A0A096MJH6-1", 
            "locus": {
                "end_pos": 50736662, 
                "strand": "+", 
                "start_pos": 50746279, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000076856", 
                        "id": "ENSRNOT00000076856", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068132", 
                        "id": "ENSRNOP00000068132", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A096MJH6-1|A0A096MK02_RAT Computationally mapped isoform of Opticin  OS=Rattus norvegicus OX=10116 GN=Optc PE=4 SV=1 CANONICAL=A0A096MK02-1", 
                "length": 352, 
                "sequence": "MGNLIRHMDPWANYLSSPWPINEGVSSCPLVWQAVIIPIRVFVSLEAAGPDGTKTSKRMYVEWIQPFPLLPFPQNLMKFLTFLSLLTLVLQEAGTASLLGEREREEKSPEEADTYASLHVGNYSLSLEDYSEVIDLSSYEELADYGDQIPEAKTSSPTLPTRTSPTSPVVPRTLPSRLTMAGPTTTGLLNSQSSHAKLRRIDLSSNSISSIHNDALRLLPALQDLILPENQLAALPVLPSGLEFLDVRLNRLQSSGIQPEAFVTLEKLQFLYLADNLLDSIPGPLPLSLRSLHLQNNKIEAMESDTFCDTTEHRHERRRQLEDIRLDGNPINLSLFPEAYFCLPRLPVGRFT"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A096MK02#A0A096MK02-1", 
            "isoform_ac": "A0A096MK02-1", 
            "locus": {
                "end_pos": 50736662, 
                "strand": "+", 
                "start_pos": 50746279, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000076673", 
                        "id": "ENSRNOT00000076673", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000068329", 
                        "id": "ENSRNOP00000068329", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A096MK02-1|A0A096MK02_RAT Isoform 1 of Opticin  OS=Rattus norvegicus OX=10116 GN=Optc PE=4 SV=1 CANONICAL=A0A096MK02-1", 
                "length": 405, 
                "sequence": "MGNLIRHMDPWANYLSSPWPINEGVSSCPLVWQAVIIPIRVFVSLEAAGPDGTKTSKRMYVEWIQPFPLLPFPQNLMKFLTFLSLLTLVLQEAGTASLLGEREREEKSPEEADTYASLHVGNYSLSLEDYSEVIDLSSYEELADYGDQIPEAKTSSPTLPTRTSPTSPVVPRTLPSRLTMAGPTTTGLLNSQSSHGLPTCLVCVCLGSSVYCDDANLENIPPLPQMTTYLYARFNHISHIQAGDFKGMTKLRRIDLSSNSISSIHNDALRLLPALQDLILPENQLAALPVLPSGLEFLDVRLNRLQSSGIQPEAFVTLEKLQFLYLADNLLDSIPGPLPLSLRSLHLQNNKIEAMESDTFCDTTEHRHERRRQLEDIRLDGNPINLSLFPEAYFCLPRLPVGRFT"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A096MK02#D3ZWK1-1", 
            "isoform_ac": "D3ZWK1-1", 
            "locus": {
                "end_pos": 50735602, 
                "strand": "+", 
                "start_pos": 50746279, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000064556", 
                        "id": "ENSRNOT00000064556", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000063610", 
                        "id": "ENSRNOP00000063610", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|D3ZWK1-1|A0A096MK02_RAT Computationally mapped isoform of Opticin  OS=Rattus norvegicus OX=10116 GN=Optc PE=4 SV=1 CANONICAL=A0A096MK02-1", 
                "length": 361, 
                "sequence": "MGNLIRHMDPWANYLSSPWPINEGVSSCPLVWQAVIIPIRVFVSLEAAGPDGTKTSKRMYVEWIQPFPLLPFPQNLMKFLTFLSLLTLVLQEAGTASLLGEREREEKSPEEADTYASLHVGNYSLSLEDYSEVIDLSSYEELADYGDQIPEAKTSSPTLPTRTSPTSPVVPRTLPSRLTMAGPTTTGLLNSQSSHGLPTCLVCVCLGSSVYCDDANLENIPPLPQMTTYLYARFNHISHIQAGDFKGMTKLRRIDLSSNSISSIHNDALRLLPALQDLILPENQLAALPVLPSGLEFLDVRLNRLQSSGIQPEAFVTLEKLQFLYLADNLLDSIPGPLPLSLRSLHLQRVISVLEPGLSDW"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-1474228", 
            "resource": "Reactome", 
            "id": "R-RNO-1474228", 
            "name": "Degradation of the extracellular matrix"
        }
    ], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q920A0-1", 
            "protein_name": "Opticin", 
            "sequence": {
                "length": 328, 
                "sequence": "MKFLAFLSLLSLVLQKAETASLLGEREREEQSPEEGDTYASLYVGNHTLSIEDYNEVIDLSNYEELADYGDQIPEAKISNLTLPTRTSPTSTVAQKTLSPNLTMAVPTTTGLLNSQSSHGLPTCLVCVCLGSSVYCDDADLENIPPLPQMTTYLYARFNHISHIQAGDFKGLTKLRRIDLSGNSISSIHNDALRLLPALQDLILPENQLAALPVLPSGIEFLDVRLNRLQSSGIQPEAFVALKKLQFLYLANNMLDSIPGPLPLSLRSLHLQNNMIETMESDTFCDTGEHRHERRQLEDIRLDGNPINLSLFPEAYFCLPRLPVGHFT"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/8652", 
                    "id": "8652", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "gene_name": "Optc", 
            "tax_id": 10090
        }, 
        {
            "uniprot_canonical_ac": "Q9UBM4-1", 
            "protein_name": "Opticin", 
            "sequence": {
                "length": 332, 
                "sequence": "MRLLAFLSLLALVLQETGTASLPRKERKRREEQMPREGDSFEVLPLRNDVLNPDNYGEVIDLSNYEELTDYGDQLPEVKVTSLAPATSISPAKSTTAPGTPSSNPTMTRPTTAGLLLSSQPNHGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/8652", 
                    "id": "8652", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "gene_name": "OPTC", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006249933.1", 
        "ac": "XP_006249933.1", 
        "name": "opticin isoform X1", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A096MK02", 
                                "id": "A0A096MK02", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "extracellular matrix", 
                        "id": "GO:0031012"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A096MK02", 
                                "id": "A0A096MK02", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "collagen fibril organization", 
                        "id": "GO:0030199"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016525", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A096MK02", 
                                "id": "A0A096MK02", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "negative regulation of angiogenesis", 
                        "id": "GO:0016525"
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0A096MK02", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Optc"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A096MK02", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Optc"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000003059", 
            "id": "ENSRNOG00000003059", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/304802", 
            "id": "304802", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", 
            "id": "IPR000372", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", 
            "id": "IPR001611", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", 
            "id": "IPR003591", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", 
            "id": "IPR032675", 
            "database": "InterPro"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/NMIETMQ/", 
            "id": "NMIETMQ", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=914775at2759", 
            "id": "914775at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF13855", 
            "id": "PF13855", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-1474228", 
            "id": "R-RNO-1474228", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_006249933.1", 
            "id": "XP_006249933.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1304916", 
            "id": "1304916", 
            "database": "RGD"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A096MK02", 
            "id": "A0A096MK02", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 45159.0, 
        "chemical_mass": 45159.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A096MK02", 
            "name": "Optc", 
            "locus": {
                "end_pos": 50735599, 
                "strand": "-", 
                "start_pos": 50746354, 
                "chromosome": "13", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000003059", 
                        "id": "ENSRNOG00000003059", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A096MK02#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Opticin"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0A096MK02", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "opticin isoform X1"
        }
    ]
}