{ "uniprot_canonical_ac": "A0A087WXM9-1", "ptm_annotation": [], "sequence": { "header": "sp|A0A087WXM9-1|MEIKN_HUMAN Isoform 1 of Meiosis-specific kinetochore protein OS=Homo sapiens OX=9606 GN=MEIKIN PE=2 SV=2 CANONICAL=A0A087WXM9-1", "length": 373, "sequence": "MWPLRVYTRKKREGQRLNLTPTPDLGSPAKAEAPPGSKRKGKVHGLSKIAEKAERSRQGGSGSGPFSPRLGVTGEKSLQENRSSEDTQDEKIASLRESVTDDLQVDSSSSNSELVSGLSLHHGMASSLLSYSVTDSYAEYKSFEESFPSPELFRKSDYLDWECPNLEEHMQWKNSTLLDTSKAVAIEKAPQFSNVSAIFSTSSEDYQKCHRKTVMTVADQNVSPKAKCASNSESDNAACEILLAEKTCPSTPEKTKKKKTNSSTPGKKNRGLLTSTPSSETAGFVIDLSSVQKASFEELFPNVSNYVNSNEIVPVSSLQENSSNEFPANASEICCIIRTSPGTRQVKNKGVIVKKKKYSLPKDTPQDIIIKMA" }, "uniprot_id": "MEIKN_HUMAN", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Human", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9", "id": "A0A087WXM9", "database": "UniProtKB" } ], "name": "Homo sapiens", "taxid": 9606 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/18718982", "type": [ "PubMed" ], "id": "18718982" } ], "title": "Association of haplotypes spanning PDZ-GEF2, LOC728637 and ACSL6 with schizophrenia in Han Chinese.", "journal": "Journal of medical genetics", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290551.1", "id": "NP_001290551.1", "database": "RefSeq" } ], "authors": "Luo XJ, Diao HB, Wang JK, Zhang H, Zhao ZM, Su B", "date": "2008" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/25533956", "type": [ "PubMed" ], "id": "25533956" } ], "title": "Meikin is a conserved regulator of meiosis-I-specific kinetochore function.", "journal": "Nature", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9", "id": "A0A087WXM9", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290551.1", "id": "NP_001290551.1", "database": "RefSeq" } ], "authors": "Ishiguro K., Kim J., Kitajima T.S., Sakuno T., Watanabe Y., Takeda N., Tanno Y., Ishiguro T., Pendas A.M., Sakakibara Y., Akiyoshi B., Kagami A., Nambu A., Yokobayashi S.", "date": "2015" } ], "uniprot_ac": "A0A087WXM9", "site_annotation": [ { "end_pos": 176, "annotation": "n_glycosylation_sequon", "start_pos": 174 }, { "end_pos": 20, "annotation": "n_glycosylation_sequon", "start_pos": 18 }, { "end_pos": 196, "annotation": "n_glycosylation_sequon", "start_pos": 194 }, { "end_pos": 223, "annotation": "n_glycosylation_sequon", "start_pos": 221 }, { "end_pos": 263, "annotation": "n_glycosylation_sequon", "start_pos": 261 }, { "end_pos": 304, "annotation": "n_glycosylation_sequon", "start_pos": 302 }, { "end_pos": 323, "annotation": "n_glycosylation_sequon", "start_pos": 321 }, { "end_pos": 331, "annotation": "n_glycosylation_sequon", "start_pos": 329 }, { "end_pos": 83, "annotation": "n_glycosylation_sequon", "start_pos": 81 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9#A0A087WXM9-1", "isoform_ac": "A0A087WXM9-1", "locus": { "end_pos": 131807239, "strand": "+", "start_pos": 131945505, "chromosome": "5", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000442687", "id": "ENST00000442687", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000488568", "id": "ENSP00000488568", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A0A087WXM9-1|MEIKN_HUMAN Isoform 1 of Meiosis-specific kinetochore protein OS=Homo sapiens OX=9606 GN=MEIKIN PE=2 SV=2 CANONICAL=A0A087WXM9-1", "length": 373, "sequence": "MWPLRVYTRKKREGQRLNLTPTPDLGSPAKAEAPPGSKRKGKVHGLSKIAEKAERSRQGGSGSGPFSPRLGVTGEKSLQENRSSEDTQDEKIASLRESVTDDLQVDSSSSNSELVSGLSLHHGMASSLLSYSVTDSYAEYKSFEESFPSPELFRKSDYLDWECPNLEEHMQWKNSTLLDTSKAVAIEKAPQFSNVSAIFSTSSEDYQKCHRKTVMTVADQNVSPKAKCASNSESDNAACEILLAEKTCPSTPEKTKKKKTNSSTPGKKNRGLLTSTPSSETAGFVIDLSSVQKASFEELFPNVSNYVNSNEIVPVSSLQENSSNEFPANASEICCIIRTSPGTRQVKNKGVIVKKKKYSLPKDTPQDIIIKMA" } }, { "url": "https://www.uniprot.org/uniprot/A0A087WXM9#A0A0G2JND4-1", "isoform_ac": "A0A0G2JND4-1", "locus": { "end_pos": 131807239, "strand": "+", "start_pos": 131945505, "chromosome": "5", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000616644", "id": "ENST00000616644", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000481155", "id": "ENSP00000481155", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0G2JND4-1|MEIKN_HUMAN Computationally mapped isoform of Meiosis-specific kinetochore protein OS=Homo sapiens OX=9606 GN=MEIKIN PE=2 SV=1 CANONICAL=A0A087WXM9-1", "length": 333, "sequence": "MWPLRVYTRKKREGQRLNLTPTPDLGSPAKAEAPPGSKRKGKVHGLSKIAEKAERSRQGGSGSGPFSPRLGVTGEKSLQENRSSEDTQDEKIASLRESVTDDLQVDSSSSNSELVSGLSLHHGMASSLLSYSVTDSYAEYKSFEESFPSPELFRKSDYLDWECPNLEEHMQWKNSTLLDTSKAVAIEKAPQFSNVSAIFSTSSEDYQKCHRKTVMTVADQNVSPKAKCASNSESDNAACEILLAEKTCPSTPEKTKKKKTNSSTPGKKNRGLLTSTPSSETAGFVFPANASEICCIIRTSPGTRQVKNKGVIVKKKKYSLPKDTPQDIIIKMA" } }, { "url": "https://www.uniprot.org/uniprot/A0A087WXM9#A0A0J9YXL7-1", "isoform_ac": "A0A0J9YXL7-1", "locus": { "end_pos": 131807238, "strand": "+", "start_pos": 131879020, "chromosome": "5", "evidence": [ { "url": "https://www.ensembl.org/id/ENST00000439905", "id": "ENST00000439905", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSP00000488457", "id": "ENSP00000488457", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A0J9YXL7-1|MEIKN_HUMAN Computationally mapped isoform of Meiosis-specific kinetochore protein OS=Homo sapiens OX=9606 GN=MEIKIN PE=2 SV=1 CANONICAL=A0A087WXM9-1", "length": 104, "sequence": "XRKLALQPLKKQRKKQIDLSSVQKASFEELFPNVSNYVNSNEIVPVSSLQENSSNEFPANASEICCIIRTSPGTRQVKNKGVIVKKKKYSLPKDTPQDIIIKMA" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:728637", "resource": "KEGG Pathway", "id": "hsa:728637", "name": "" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9#function", "annotation": "Key regulator of kinetochore function during meiosis I: required both for mono-orientation of kinetochores on sister chromosomes and protection of centromeric cohesin from separase-mediated cleavage. Acts by facilitating kinetochore mono-orientation during meiosis I, when kinetochores on sister chromosomes face the same direction and are thus captured and pulled by spindle fibers from the same pole. Also required to prevent cleavage of cohesin at centromeres during meiosis I, possibly by acting as a regulator of the shugoshin-dependent protection pathway. Acts in collaboration with PLK1: required for PLK1 enrichment to kinetochores. Not required during meiosis II or mitosis.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9#function", "id": "A0A087WXM9", "database": "UniProtKB" } ] }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290551.1", "annotation": "Single marker analysis indicated that SNP5 (rs1355095) in LOC728637 is associated with schizophrenia in Han Chinese.", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290551.1", "id": "NP_001290551.1", "database": "RefSeq" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q5F2C3-1", "protein_name": "Meiosis-specific kinetochore protein", "sequence": { "length": 434, "sequence": "MDKIWHMGPRGDYTRKKRAGERLNLTPKPDLALPGRTEALPGLKGKGKEQGLRKITEKKELSRLTGSSSQRPSLLSVTGGEHLQENSPGQETPEEKTPPCETVTDTFEMDSLLSSTELVSGPAEQDDFSSCLPSCSNAELHTESTDERGSSFPSPELFRGSDCLDWEHPKLEDYMFYKNSTLLDTSKAVVIEKAPQFANLSAVLSSSSKNYEKRHRKIGMTLAAQHLSPEPKYASNLASVVDNAASEVVFAEKTGPPTTEKTQKKPENESEDSGPLVQTKLSSGHPDNKALCSPLSSALESTAVRYTLLPQPLEPVLKKGCILPDKQSKALLTSTPSSDIAEFVIDLSPVQNVSFEELFPNVSNYVNSSEVVPVSSLQESSSNEFSPNTSEICCIIRSSPGTRQMRRKDPAVKNRCSPPKDVPLDIIMKTNGRT" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/54900", "id": "54900", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A0A087WXM9/", "id": "A0A087WXM9", "database": "OMA" } ], "common_name": "Mouse", "organism": "Mus musculus", "gene_name": "Meikin", "tax_id": 10090 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290551.1", "ac": "NP_001290551.1", "name": "meiosis-specific kinetochore protein", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000777", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9", "id": "A0A087WXM9", "database": "UniProtKB" } ], "name": "condensed chromosome kinetochore", "id": "GO:0000777" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000780", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9", "id": "A0A087WXM9", "database": "UniProtKB" } ], "name": "condensed nuclear chromosome, centromeric region", "id": "GO:0000780" } ], "total": 2, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045143", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9", "id": "A0A087WXM9", "database": "UniProtKB" } ], "name": "homologous chromosome segregation", "id": "GO:0045143" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007060", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9", "id": "A0A087WXM9", "database": "UniProtKB" } ], "name": "male meiosis chromosome segregation", "id": "GO:0007060" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010789", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9", "id": "A0A087WXM9", "database": "UniProtKB" } ], "name": "meiotic sister chromatid cohesion involved in meiosis I", "id": "GO:0010789" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016321", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9", "id": "A0A087WXM9", "database": "UniProtKB" } ], "name": "female meiosis chromosome segregation", "id": "GO:0016321" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051754", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9", "id": "A0A087WXM9", "database": "UniProtKB" } ], "name": "meiotic sister chromatid cohesion, centromeric", "id": "GO:0051754" } ], "total": 5, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A087WXM9", "type": "synonym", "resource": "RefSeq", "name": "MEIKIN" }, { "url": "https://www.uniprot.org/uniprot/A0A087WXM9", "type": "recommended", "resource": "UniProtKB", "name": "MEIKIN" } ], "pro_annotation": [], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" }, { "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A087WXM9", "id": "A0A087WXM9", "database": "BioMuta" }, { "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=MEIKIN", "id": "MEIKIN", "database": "GeneCards" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/728637", "id": "728637", "database": "GeneID" }, { "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=51253", "id": "51253", "database": "HGNC" }, { "url": "https://www.ebi.ac.uk/intact/interactors/id:A0A087WXM9*", "id": "A0A087WXM9", "database": "IntAct" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR034545", "id": "IPR034545", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+hsa:728637", "id": "hsa:728637", "database": "KEGG Pathway" }, { "url": "http://www.omim.org/entry/616223", "id": "616223", "database": "MIM" }, { "url": "https://www.nextprot.org/entry/NX_A0A087WXM9", "id": "NX_A0A087WXM9", "database": "neXtProt" }, { "url": "https://omabrowser.org/oma/group/NEFPANA/", "id": "NEFPANA", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=1201334at2759", "id": "1201334at2759", "database": "OrthoDB" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38006", "id": "PTHR38006", "database": "PANTHER" }, { "url": "https://pharos.nih.gov/targets/A0A087WXM9", "id": "A0A087WXM9", "database": "PHAROS" }, { "url": "http://purl.obolibrary.org/obo/PR_PR_A0A087WXM9", "id": "PR_A0A087WXM9", "database": "PRO" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001290551.1", "id": "NP_001290551.1", "database": "RefSeq" }, { "url": "https://www.uniprot.org/uniprot/A0A087WXM9", "id": "A0A087WXM9", "database": "UniProtKB" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 40829.0, "chemical_mass": 40829.0 }, "expression_tissue": [ { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000007", "uberon": "0000007", "name": "Pituitary gland" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000007", "uberon": "0000007", "name": "Pituitary gland" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000178", "uberon": "0000178", "name": "Blood" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000458", "uberon": "0000458", "name": "Endocervix" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000458", "uberon": "0000458", "name": "Endocervix" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000473", "uberon": "0000473", "name": "Testis" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000948", "uberon": "0000948", "name": "Heart" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000948", "uberon": "0000948", "name": "Heart" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000955", "uberon": "0000955", "name": "Brain" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000955", "uberon": "0000955", "name": "Brain" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000992", "uberon": "0000992", "name": "Ovary" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000996", "uberon": "0000996", "name": "Vagina" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0000996", "uberon": "0000996", "name": "Vagina" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001043", "uberon": "0001043", "name": "Esophagus" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001150", "uberon": "0001150", "name": "Body of pancreas" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001150", "uberon": "0001150", "name": "Body of pancreas" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001155", "uberon": "0001155", "name": "Colon" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001160", "uberon": "0001160", "name": "Fundus of stomach" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001160", "uberon": "0001160", "name": "Fundus of stomach" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001161", "uberon": "0001161", "name": "Body of stomach" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001161", "uberon": "0001161", "name": "Body of stomach" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001255", "uberon": "0001255", "name": "Urinary bladder" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0001987", "uberon": "0001987", "name": "Placenta" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002046", "uberon": "0002046", "name": "Thyroid gland" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002046", "uberon": "0002046", "name": "Thyroid gland" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002048", "uberon": "0002048", "name": "Lung" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002107", "uberon": "0002107", "name": "Liver" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002367", "uberon": "0002367", "name": "Prostate gland" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002367", "uberon": "0002367", "name": "Prostate gland" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0002369", "uberon": "0002369", "name": "Adrenal gland" }, "present": "yes", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] }, { "tissue": { "url": "http://purl.obolibrary.org/obo/UBERON_0009853", "uberon": "0009853", "name": "Body of uterus" }, "present": "no", "evidence": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSG00000239642", "id": "ENSG00000239642", "database": "Bgee" } ] } ], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9", "name": "MEIKIN", "locus": { "end_pos": 131806993, "strand": "-", "start_pos": 131945698, "chromosome": "5", "evidence": [ { "url": "https://www.ensembl.org/id/ENSG00000239642", "id": "ENSG00000239642", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A0A087WXM9#names_and_taxonomy", "type": "recommended", "resource": "UniProtKB", "name": "Meiosis-specific kinetochore protein" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A087WXM9", "type": "synonym", "resource": "RefSeq", "name": "meiosis-specific kinetochore protein" } ] }