{
    "uniprot_canonical_ac": "A0A087WS15-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A0A087WS15-1|A0A087WS15_MOUSE Isoform 1 of Cytochrome P450, family 4, subfamily a, polypeptide 30b  OS=Mus musculus OX=10090 GN=Cyp4a30b PE=3 SV=1 CANONICAL=A0A087WS15-1", 
        "length": 508, 
        "sequence": "MSIFELSHITNVFGIFGLLQVVSLLGLLLLLLKSAQYYLHRQWLIKSLQQFPPAPPPQWLFGNTLKDQDLQQILLCVEKFPSTYVRWLWGNHARVVIYDPDYMKVILGRSDPKVVRSYSFFAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVGIMVDSVHVMLDKWEQLVDQDCPLEIYQDISLMTMETMMKCAFSYQGSVQLEENSKSYIKAVEDLTHLIYLRVRNGFHQNNTIYSLSSNGRSFYHACQIAHKHTERVIRMRKAQLQNEAELEKFRKKKRLDFLDILLFAQTEDGKSLSDEDVRAEMDTFMFEGHNTTASGISWIFYALATHPEHQQRCREEVKSILGNGTSVTLNHLDQMPYTTMCIKEALRLYPPIPGASRELSSPVTFPDGCSLPKGFLVTLSFYGLHHNPRLRPNAEVFDPSRFAPGAPRQTHAFLPFSAGTRNCIGKQFTMNELKVAVALTLLRFELLPDPTRVPILVSKIVLKSKNGIYLHTKKLK"
    }, 
    "uniprot_id": "A0A087WS15_MOUSE", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
                    "id": "A0A087WS15", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "publication": [], 
    "uniprot_ac": "A0A087WS15", 
    "site_annotation": [
        {
            "end_pos": 239, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 237
        }, 
        {
            "end_pos": 324, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 322
        }, 
        {
            "end_pos": 357, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 355
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A087WS15#A0A087WS15-1", 
            "isoform_ac": "A0A087WS15-1", 
            "locus": {
                "end_pos": 115452604, 
                "strand": "-", 
                "start_pos": 115471059, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000119958", 
                        "id": "ENSMUST00000119958", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000140857", 
                        "id": "ENSMUSP00000140857", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A087WS15-1|A0A087WS15_MOUSE Isoform 1 of Cytochrome P450, family 4, subfamily a, polypeptide 30b  OS=Mus musculus OX=10090 GN=Cyp4a30b PE=3 SV=1 CANONICAL=A0A087WS15-1", 
                "length": 508, 
                "sequence": "MSIFELSHITNVFGIFGLLQVVSLLGLLLLLLKSAQYYLHRQWLIKSLQQFPPAPPPQWLFGNTLKDQDLQQILLCVEKFPSTYVRWLWGNHARVVIYDPDYMKVILGRSDPKVVRSYSFFAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVGIMVDSVHVMLDKWEQLVDQDCPLEIYQDISLMTMETMMKCAFSYQGSVQLEENSKSYIKAVEDLTHLIYLRVRNGFHQNNTIYSLSSNGRSFYHACQIAHKHTERVIRMRKAQLQNEAELEKFRKKKRLDFLDILLFAQTEDGKSLSDEDVRAEMDTFMFEGHNTTASGISWIFYALATHPEHQQRCREEVKSILGNGTSVTLNHLDQMPYTTMCIKEALRLYPPIPGASRELSSPVTFPDGCSLPKGFLVTLSFYGLHHNPRLRPNAEVFDPSRFAPGAPRQTHAFLPFSAGTRNCIGKQFTMNELKVAVALTLLRFELLPDPTRVPILVSKIVLKSKNGIYLHTKKLK"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:435802", 
            "resource": "KEGG Pathway", 
            "id": "mmu:435802", 
            "name": ""
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211935", 
            "resource": "Reactome", 
            "id": "R-MMU-211935", 
            "name": "Fatty acids"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211958", 
            "resource": "Reactome", 
            "id": "R-MMU-211958", 
            "name": "Miscellaneous substrates"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211979", 
            "resource": "Reactome", 
            "id": "R-MMU-211979", 
            "name": "Eicosanoids"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2142691", 
            "resource": "Reactome", 
            "id": "R-MMU-2142691", 
            "name": "Synthesis of Leukotrienes (LT) and Eoxins (EX)"
        }
    ], 
    "function": [], 
    "orthologs": [], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093655.1", 
        "ac": "NP_001093655.1", 
        "name": "cytochrome P450, family 4, subfamily a, polypeptide 30b", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018685", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
                                "id": "A0A087WS15", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "alkane 1-monooxygenase activity", 
                        "id": "GO:0018685"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008391", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
                                "id": "A0A087WS15", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "arachidonic acid monooxygenase activity", 
                        "id": "GO:0008391"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
                                "id": "A0A087WS15", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "iron ion binding", 
                        "id": "GO:0005506"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
                                "id": "A0A087WS15", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "heme binding", 
                        "id": "GO:0020037"
                    }
                ], 
                "total": 4, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
                                "id": "A0A087WS15", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "intracellular membrane-bounded organelle", 
                        "id": "GO:0043231"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
                                "id": "A0A087WS15", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }
                ], 
                "total": 2, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046456", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
                                "id": "A0A087WS15", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "icosanoid biosynthetic process", 
                        "id": "GO:0046456"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001822", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
                                "id": "A0A087WS15", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "kidney development", 
                        "id": "GO:0001822"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043651", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
                                "id": "A0A087WS15", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "linoleic acid metabolic process", 
                        "id": "GO:0043651"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019369", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
                                "id": "A0A087WS15", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "arachidonic acid metabolic process", 
                        "id": "GO:0019369"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048252", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
                                "id": "A0A087WS15", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "lauric acid metabolic process", 
                        "id": "GO:0048252"
                    }
                ], 
                "total": 5, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0A087WS15", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Cyp4a30; Cyp4a30b-ps"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0A087WS15", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Cyp4a30b"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Cyp4a30b"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000084346", 
            "id": "ENSMUSG00000084346", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/435802", 
            "id": "435802", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", 
            "id": "IPR001128", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", 
            "id": "IPR002401", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", 
            "id": "IPR017972", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", 
            "id": "IPR036396", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:435802", 
            "id": "mmu:435802", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:3717145", 
            "id": "3717145", 
            "database": "MGI"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/HYYSWIN/", 
            "id": "HYYSWIN", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=1247045at2759", 
            "id": "1247045at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00067", 
            "id": "PF00067", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211935", 
            "id": "R-MMU-211935", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211958", 
            "id": "R-MMU-211958", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-211979", 
            "id": "R-MMU-211979", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-2142691", 
            "id": "R-MMU-2142691", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093655.1", 
            "id": "NP_001093655.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
            "id": "A0A087WS15", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [
        {
            "synonyms": [
                {
                    "id": "MONDO:0033004", 
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004", 
                    "resource": "MONDO", 
                    "name": "polycystic kidney disease 4", 
                    "description": ""
                }, 
                {
                    "id": "MONDO:0033004", 
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004", 
                    "resource": "MONDO", 
                    "name": "PKD3, formerly", 
                    "description": ""
                }, 
                {
                    "id": "MONDO:0033004", 
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004", 
                    "resource": "MONDO", 
                    "name": "PKD3", 
                    "description": ""
                }, 
                {
                    "id": "MONDO:0033004", 
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004", 
                    "resource": "MONDO", 
                    "name": "polycystic kidney disease, infantile, type 1", 
                    "description": ""
                }, 
                {
                    "id": "MONDO:0033004", 
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004", 
                    "resource": "MONDO", 
                    "name": "polycystic kidney disease 4 with or without polycystic liver disease; PKD4", 
                    "description": ""
                }, 
                {
                    "id": "MONDO:0033004", 
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004", 
                    "resource": "MONDO", 
                    "name": "PKD4", 
                    "description": ""
                }, 
                {
                    "id": "MONDO:0033004", 
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004", 
                    "resource": "MONDO", 
                    "name": "hepatic fibrosis, congenital", 
                    "description": ""
                }, 
                {
                    "id": "MONDO:0033004", 
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004", 
                    "resource": "MONDO", 
                    "name": "polycystic kidney and hepatic disease 1", 
                    "description": ""
                }, 
                {
                    "id": "MONDO:0033004", 
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004", 
                    "resource": "MONDO", 
                    "name": "polycystic kidney disease, autosomal recessive", 
                    "description": ""
                }, 
                {
                    "id": "MONDO:0033004", 
                    "url": "https://monarchinitiative.org/disease/MONDO:0033004", 
                    "resource": "MONDO", 
                    "name": "polycystic kidney disease 4 with or without hepatic disease", 
                    "description": ""
                }, 
                {
                    "id": "DOID:0110861", 
                    "url": "http://disease-ontology.org/term/DOID:0110861", 
                    "resource": "Disease Ontology", 
                    "name": "Arpkd", 
                    "description": ""
                }, 
                {
                    "id": "DOID:0110861", 
                    "url": "http://disease-ontology.org/term/DOID:0110861", 
                    "resource": "Disease Ontology", 
                    "name": "Pkhd1", 
                    "description": ""
                }, 
                {
                    "id": "DOID:0110861", 
                    "url": "http://disease-ontology.org/term/DOID:0110861", 
                    "resource": "Disease Ontology", 
                    "name": "Polycystic Kidney Disease, Infantile, Type I", 
                    "description": ""
                }, 
                {
                    "id": "DOID:0110861", 
                    "url": "http://disease-ontology.org/term/DOID:0110861", 
                    "resource": "Disease Ontology", 
                    "name": "Polycystic Kidney and Hepatic Disease 1", 
                    "description": ""
                }
            ], 
            "recommended_name": {
                "id": "DOID:0110861", 
                "url": "http://disease-ontology.org/term/DOID:0110861", 
                "resource": "Disease Ontology", 
                "name": "autosomal recessive polycystic kidney disease", 
                "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal recessive fashion."
            }, 
            "evidence": [
                {
                    "url": "https://www.alliancegenome.org/gene/0110861#disease-associations", 
                    "id": "0110861", 
                    "database": "Alliance of Genome Resources"
                }
            ]
        }, 
        {
            "synonyms": [
                {
                    "id": "DOID:10763", 
                    "url": "http://disease-ontology.org/term/DOID:10763", 
                    "resource": "Disease Ontology", 
                    "name": "HTN", 
                    "description": ""
                }, 
                {
                    "id": "DOID:10763", 
                    "url": "http://disease-ontology.org/term/DOID:10763", 
                    "resource": "Disease Ontology", 
                    "name": "High blood pressure", 
                    "description": ""
                }, 
                {
                    "id": "DOID:10763", 
                    "url": "http://disease-ontology.org/term/DOID:10763", 
                    "resource": "Disease Ontology", 
                    "name": "hyperpiesia", 
                    "description": ""
                }, 
                {
                    "id": "DOID:10763", 
                    "url": "http://disease-ontology.org/term/DOID:10763", 
                    "resource": "Disease Ontology", 
                    "name": "vascular hypertensive disorder", 
                    "description": ""
                }
            ], 
            "recommended_name": {
                "id": "DOID:10763", 
                "url": "http://disease-ontology.org/term/DOID:10763", 
                "resource": "Disease Ontology", 
                "name": "hypertension", 
                "description": "An artery disease characterized by chronic elevated blood pressure in the arteries."
            }, 
            "evidence": [
                {
                    "url": "https://www.alliancegenome.org/gene/10763#disease-associations", 
                    "id": "10763", 
                    "database": "Alliance of Genome Resources"
                }
            ]
        }
    ], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 58533.0, 
        "chemical_mass": 58533.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A087WS15", 
            "name": "Cyp4a30b", 
            "locus": {
                "end_pos": 115471062, 
                "strand": "+", 
                "start_pos": 115452604, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000084346", 
                        "id": "ENSMUSG00000084346", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A087WS15#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Cytochrome P450, family 4, subfamily a, polypeptide 30b"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0A087WS15", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "cytochrome P450, family 4, subfamily a, polypeptide 30b, pseudogene"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0A087WS15", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "cytochrome P450, family 4, subfamily a, polypeptide 30b"
        }
    ]
}