{
    "uniprot_canonical_ac": "A0A075B7F1-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A0A075B7F1-1|A0A075B7F1_HUMAN Isoform 1 of Immunoglobulin heavy variable 3/OR16-8 (non-functional)  OS=Homo sapiens OX=9606 GN=IGHV3OR16-8 PE=1 SV=1 CANONICAL=A0A075B7F1-1", 
        "length": 116, 
        "sequence": "MEFGLNWVFLVAIIKGAQCEVQLVESGGGLVQPGGSLRLSCPASGFTFSNHYMSWVRQAPGKGLEWVSYISGDSGYTNYADSVKGRFTISRDNANNSPYLQMNSLRAEDTAVYYCV"
    }, 
    "uniprot_id": "A0A075B7F1_HUMAN", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [
        "glycoprotein", 
        "reported_with_glycan.glyconnect"
    ], 
    "species": [
        {
            "common_name": "Human", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
                    "id": "A0A075B7F1", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/29741879", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "29741879"
                }
            ], 
            "title": "Reanalysis of Global Proteomic and Phosphoproteomic Data Identified a Large Number of Glycopeptides.", 
            "journal": "Analytical chemistry", 
            "evidence": [
                {
                    "url": "https://glyconnect.expasy.org/browser/proteins/1661", 
                    "id": "1661", 
                    "database": "GlyConnect"
                }
            ], 
            "authors": "Hu Y, Shah P, Clark DJ, Ao M, Zhang H", 
            "date": "2018"
        }
    ], 
    "uniprot_ac": "A0A075B7F1", 
    "site_annotation": [
        {
            "end_pos": 97, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 95
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A075B7F1#A0A075B7F1-1", 
            "isoform_ac": "A0A075B7F1-1", 
            "locus": {
                "end_pos": 33009175, 
                "strand": "-", 
                "start_pos": 33009619, 
                "chromosome": "16", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000565407", 
                        "id": "ENST00000565407", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000474964", 
                        "id": "ENSP00000474964", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A075B7F1-1|A0A075B7F1_HUMAN Isoform 1 of Immunoglobulin heavy variable 3/OR16-8 (non-functional)  OS=Homo sapiens OX=9606 GN=IGHV3OR16-8 PE=1 SV=1 CANONICAL=A0A075B7F1-1", 
                "length": 116, 
                "sequence": "MEFGLNWVFLVAIIKGAQCEVQLVESGGGLVQPGGSLRLSCPASGFTFSNHYMSWVRQAPGKGLEWVSYISGDSGYTNYADSVKGRFTISRDNANNSPYLQMNSLRAEDTAVYYCV"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [
        {
            "sequence_org": "Q", 
            "start_pos": 22, 
            "alt_nt": "C", 
            "chr_id": "16", 
            "ref_nt": "G", 
            "chr_pos": "33020658", 
            "disease": [
                {
                    "synonyms": [], 
                    "recommended_name": {
                        "id": "DOID:1324", 
                        "url": "http://disease-ontology.org/term/DOID:1324", 
                        "resource": "Disease Ontology", 
                        "name": "lung cancer", 
                        "description": "A respiratory system cancer that is located_in the lung."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A075B7F1", 
                    "id": "A0A075B7F1", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "1.6", 
            "sequence_mut": "H", 
            "subjects_tested": "1514", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 2 out of 6 filters: patient freq. (1.6%); patient count (24/1514).", 
            "end_pos": 22, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "24"
        }, 
        {
            "sequence_org": "N", 
            "start_pos": 95, 
            "alt_nt": "G", 
            "chr_id": "16", 
            "ref_nt": "T", 
            "chr_pos": "33020877", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "Thyroid gland neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumour of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "neoplasm of thyroid gland", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:1781", 
                            "url": "http://disease-ontology.org/term/DOID:1781", 
                            "resource": "Disease Ontology", 
                            "name": "thyroid neoplasm", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:1781", 
                        "url": "http://disease-ontology.org/term/DOID:1781", 
                        "resource": "Disease Ontology", 
                        "name": "thyroid gland cancer", 
                        "description": "An endocrine gland cancer located in the thryoid gland located in the neck below the thyroid cartilage."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A075B7F1", 
                    "id": "A0A075B7F1", 
                    "database": "BioMuta"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs370645488", 
                    "id": "rs370645488", 
                    "database": "dbSNP"
                }, 
                {
                    "url": "https://www.ensembl.org/homo_sapiens/Variation/Explore?v=rs370645488", 
                    "id": "rs370645488", 
                    "database": "1000Genomes"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs370645488", 
                    "id": "rs370645488", 
                    "database": "ExAC"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/snp/rs370645488#frequency_tab", 
                    "id": "rs370645488", 
                    "database": "TOPMed"
                }, 
                {
                    "url": "http://gnomad.broadinstitute.org/awesome?query=rs370645488", 
                    "id": "rs370645488", 
                    "database": "gnomAD"
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            ], 
            "glycoeffect": [
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            ], 
            "frequency": "6.0", 
            "sequence_mut": "K", 
            "subjects_tested": "50", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease", 
                "ebi", 
                "germline"
            ], 
            "annotation": "Somatic mutation passed 2 out of 6 filters: patient freq. (6.0%); n-glyco-sequon-loss (NNS->KNS).", 
            "end_pos": 95, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "3"
        }, 
        {
            "sequence_org": "N", 
            "start_pos": 95, 
            "alt_nt": "G", 
            "chr_id": "16", 
            "ref_nt": "A", 
            "chr_pos": "33020876", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:263", 
                            "url": "http://disease-ontology.org/term/DOID:263", 
                            "resource": "Disease Ontology", 
                            "name": "malignant neoplasm of kidney except pelvis", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:263", 
                            "url": "http://disease-ontology.org/term/DOID:263", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumour of kidney", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:263", 
                            "url": "http://disease-ontology.org/term/DOID:263", 
                            "resource": "Disease Ontology", 
                            "name": "renal cancer", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:263", 
                        "url": "http://disease-ontology.org/term/DOID:263", 
                        "resource": "Disease Ontology", 
                        "name": "kidney cancer", 
                        "description": "A urinary system cancer that is located_in the kidney."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A075B7F1", 
                    "id": "A0A075B7F1", 
                    "database": "BioMuta"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs1357753418", 
                    "id": "rs1357753418", 
                    "database": "dbSNP"
                }, 
                {
                    "url": "http://gnomad.broadinstitute.org/awesome?query=rs1357753418", 
                    "id": "rs1357753418", 
                    "database": "gnomAD"
                }
            ], 
            "glycoeffect": [
                "n-glyco-sequon-loss", 
                "n-glyco-sequon-gain"
            ], 
            "frequency": "0.2", 
            "sequence_mut": "S", 
            "subjects_tested": "655", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease", 
                "ebi", 
                "germline"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-loss (NNS->SNS); n-glyco-sequon-gain (NAN->NAS).", 
            "end_pos": 95, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "L", 
            "start_pos": 105, 
            "alt_nt": "C", 
            "chr_id": "16", 
            "ref_nt": "T", 
            "chr_pos": "33020906", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "malignant Ovarian tumor", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "malignant tumour of ovary", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "ovarian neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "ovary neoplasm", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "primary ovarian cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:2394", 
                            "url": "http://disease-ontology.org/term/DOID:2394", 
                            "resource": "Disease Ontology", 
                            "name": "tumor of the Ovary", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:2394", 
                        "url": "http://disease-ontology.org/term/DOID:2394", 
                        "resource": "Disease Ontology", 
                        "name": "ovarian cancer", 
                        "description": "A female reproductive organ cancer that is located_in the ovary."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A075B7F1", 
                    "id": "A0A075B7F1", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [], 
            "frequency": "1.1", 
            "sequence_mut": "P", 
            "subjects_tested": "93", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: patient freq. (1.1%).", 
            "end_pos": 105, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "T", 
            "start_pos": 47, 
            "alt_nt": "A", 
            "chr_id": "16", 
            "ref_nt": "C", 
            "chr_pos": "33020732", 
            "disease": [
                {
                    "synonyms": [
                        {
                            "id": "DOID:10534", 
                            "url": "http://disease-ontology.org/term/DOID:10534", 
                            "resource": "Disease Ontology", 
                            "name": "gastric cancer", 
                            "description": ""
                        }, 
                        {
                            "id": "DOID:10534", 
                            "url": "http://disease-ontology.org/term/DOID:10534", 
                            "resource": "Disease Ontology", 
                            "name": "gastric neoplasm", 
                            "description": ""
                        }
                    ], 
                    "recommended_name": {
                        "id": "DOID:10534", 
                        "url": "http://disease-ontology.org/term/DOID:10534", 
                        "resource": "Disease Ontology", 
                        "name": "stomach cancer", 
                        "description": "A gastrointestinal system cancer that is located_in the stomach."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A075B7F1", 
                    "id": "A0A075B7F1", 
                    "database": "BioMuta"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs892529943", 
                    "id": "rs892529943", 
                    "database": "dbSNP"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/snp/rs892529943#frequency_tab", 
                    "id": "rs892529943", 
                    "database": "TOPMed"
                }, 
                {
                    "url": "http://gnomad.broadinstitute.org/awesome?query=rs892529943", 
                    "id": "rs892529943", 
                    "database": "gnomAD"
                }
            ], 
            "glycoeffect": [
                "n-glyco-sequon-gain", 
                "o-glyco-site-loss"
            ], 
            "frequency": "0.1", 
            "sequence_mut": "N", 
            "subjects_tested": "1044", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease", 
                "ebi", 
                "germline"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-gain (TFS->NFS).", 
            "end_pos": 47, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "A", 
            "start_pos": 80, 
            "alt_nt": "T", 
            "chr_id": "16", 
            "ref_nt": "G", 
            "chr_pos": "33020830", 
            "disease": [
                {
                    "synonyms": [], 
                    "recommended_name": {
                        "id": "DOID:1324", 
                        "url": "http://disease-ontology.org/term/DOID:1324", 
                        "resource": "Disease Ontology", 
                        "name": "lung cancer", 
                        "description": "A respiratory system cancer that is located_in the lung."
                    }
                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A075B7F1", 
                    "id": "A0A075B7F1", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [
                "n-glyco-sequon-gain"
            ], 
            "frequency": "0.1", 
            "sequence_mut": "S", 
            "subjects_tested": "689", 
            "keywords": [
                "biomuta", 
                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-gain (NYA->NYS).", 
            "end_pos": 80, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "1"
        }, 
        {
            "sequence_org": "A", 
            "alt_nt": "null", 
            "chr_id": "16", 
            "ref_nt": "A", 
            "chr_pos": "33009509G>", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs373565926", 
                    "id": "rs373565926", 
                    "database": "dbSNP"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs373565926", 
                    "id": "rs373565926", 
                    "database": "ExAC"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/snp/rs373565926#frequency_tab", 
                    "id": "rs373565926", 
                    "database": "TOPMed"
                }, 
                {
                    "url": "http://gnomad.broadinstitute.org/awesome?query=rs373565926", 
                    "id": "rs373565926", 
                    "database": "gnomAD"
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            ], 
            "glycoeffect": [
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            ], 
            "sequence_mut": "T", 
            "start_pos": 80, 
            "keywords": [
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                "germline"
            ], 
            "end_pos": 80, 
            "minor_allelic_frequency": "", 
            "annotation": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (NYA->NYT)."
        }, 
        {
            "sequence_org": "P", 
            "start_pos": 98, 
            "alt_nt": "A", 
            "chr_id": "16", 
            "ref_nt": "C", 
            "chr_pos": "33020884", 
            "disease": [
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                    "synonyms": [], 
                    "recommended_name": {
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                        "url": "http://disease-ontology.org/term/DOID:1324", 
                        "resource": "Disease Ontology", 
                        "name": "lung cancer", 
                        "description": "A respiratory system cancer that is located_in the lung."
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                }
            ], 
            "evidence": [
                {
                    "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A075B7F1", 
                    "id": "A0A075B7F1", 
                    "database": "BioMuta"
                }
            ], 
            "glycoeffect": [
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            "frequency": "0.3", 
            "sequence_mut": "T", 
            "subjects_tested": "689", 
            "keywords": [
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                "somatic", 
                "cancer", 
                "disease"
            ], 
            "annotation": "Somatic mutation passed 1 out of 6 filters: n-glyco-sequon-gain (NSP->NST).", 
            "end_pos": 98, 
            "minor_allelic_frequency": "", 
            "subjects_positive": "2"
        }
    ], 
    "cluster_types": [], 
    "refseq": {}, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034987", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
                                "id": "A0A075B7F1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "immunoglobulin receptor binding", 
                        "id": "GO:0034987"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003823", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
                                "id": "A0A075B7F1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "antigen binding", 
                        "id": "GO:0003823"
                    }
                ], 
                "total": 2, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
                                "id": "A0A075B7F1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "external side of plasma membrane", 
                        "id": "GO:0009897"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042571", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
                                "id": "A0A075B7F1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "immunoglobulin complex, circulating", 
                        "id": "GO:0042571"
                    }
                ], 
                "total": 2, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006911", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
                                "id": "A0A075B7F1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "phagocytosis, engulfment", 
                        "id": "GO:0006911"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
                                "id": "A0A075B7F1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "innate immune response", 
                        "id": "GO:0045087"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
                                "id": "A0A075B7F1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "B cell receptor signaling pathway", 
                        "id": "GO:0050853"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
                                "id": "A0A075B7F1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "defense response to bacterium", 
                        "id": "GO:0042742"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006910", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
                                "id": "A0A075B7F1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "phagocytosis, recognition", 
                        "id": "GO:0006910"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050871", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
                                "id": "A0A075B7F1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of B cell activation", 
                        "id": "GO:0050871"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006958", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
                                "id": "A0A075B7F1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "complement activation, classical pathway", 
                        "id": "GO:0006958"
                    }
                ], 
                "total": 7, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "IGHV3OR16-8"
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000271130", 
            "id": "ENSG00000271130", 
            "database": "Bgee"
        }, 
        {
            "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A0A075B7F1", 
            "id": "A0A075B7F1", 
            "database": "BioMuta"
        }, 
        {
            "url": "http://www.genecards.org/cgi-bin/carddisp.pl?gene=IGHV3OR16-8", 
            "id": "IGHV3OR16-8", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=5643", 
            "id": "5643", 
            "database": "HGNC"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", 
            "id": "IPR007110", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", 
            "id": "IPR013106", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", 
            "id": "IPR013783", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", 
            "id": "IPR036179", 
            "database": "InterPro"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/IWIRQAP/", 
            "id": "IWIRQAP", 
            "database": "OMA"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF07686", 
            "id": "PF07686", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
            "id": "A0A075B7F1", 
            "database": "UniProtKB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [
        {
            "residue": "Asn", 
            "site_category": "reported_with_glycan", 
            "end_pos": 95, 
            "evidence": [
                {
                    "url": "https://glyconnect.expasy.org/browser/proteins/1661", 
                    "id": "1661", 
                    "database": "GlyConnect"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/29741879", 
                    "id": "29741879", 
                    "database": "PubMed"
                }
            ], 
            "subtype": "", 
            "relation": "attached", 
            "start_pos": 95, 
            "glytoucan_ac": "G91473PK", 
            "type": "N-linked"
        }
    ], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 12703.0, 
        "chemical_mass": 12703.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A075B7F1", 
            "name": "IGHV3OR16-8", 
            "locus": {
                "end_pos": 33009620, 
                "strand": "+", 
                "start_pos": 33009175, 
                "chromosome": "16", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000271130", 
                        "id": "ENSG00000271130", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0A075B7F1#names_and_taxonomy", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Immunoglobulin heavy variable 3/OR16-8 (non-functional)"
        }
    ]
}
