{
    "disease_id": "DOID:0060453", 
    "synonyms": [
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "Reis-Bcklers corneal dystrophy"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "granular corneal dystrophy, type 3"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "corneal dystrophy of Bowman layer type 1"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "corneal dystrophy, REIS-Bucklers type; CDRB"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "granular corneal dystrophy type III"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "geographic corneal dystrophy"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "Reis Bucklers dystrophy"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "anterior limiting membrane dystrophy type 1"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "superficial granular corneal dystrophy"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "granular corneal dystrophy type 3"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "corneal dystrophy, geographic"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "atypical granular corneal dystrophy"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "corneal dystrophy of Bowman Layer, type 1"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "corneal dystrophy geographic"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "CDB1"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "Reis Bucklers corneal dystrophy"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "CDRB"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "corneal dystrophy of Bowman layer type I"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "corneal dystrophy, REIS-Bucklers type"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "corneal dystrophy Reis Bucklers type"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "anterior limiting membrane dystrophy type I"
        }, 
        {
            "url": "https://monarchinitiative.org/disease/MONDO:0012043", 
            "description": "", 
            "resource": "MONDO", 
            "id": "MONDO:0012043", 
            "name": "RBCD"
        }, 
        {
            "url": "http://disease-ontology.org/term/DOID:0060453", 
            "description": "", 
            "resource": "Disease Ontology", 
            "id": "DOID:0060453", 
            "name": "RBCD"
        }, 
        {
            "url": "http://disease-ontology.org/term/DOID:0060453", 
            "description": "", 
            "resource": "Disease Ontology", 
            "id": "DOID:0060453", 
            "name": "anterior limiting membrane dystrophy type I"
        }, 
        {
            "url": "http://disease-ontology.org/term/DOID:0060453", 
            "description": "", 
            "resource": "Disease Ontology", 
            "id": "DOID:0060453", 
            "name": "corneal dystrophy of Bowman layer type I"
        }, 
        {
            "url": "http://disease-ontology.org/term/DOID:0060453", 
            "description": "", 
            "resource": "Disease Ontology", 
            "id": "DOID:0060453", 
            "name": "geographic corneal dystrophy"
        }, 
        {
            "url": "http://disease-ontology.org/term/DOID:0060453", 
            "description": "", 
            "resource": "Disease Ontology", 
            "id": "DOID:0060453", 
            "name": "granular corneal dystrophy type III"
        }
    ], 
    "recommended_name": {
        "url": "http://disease-ontology.org/term/DOID:0060453", 
        "description": "An epithelial-stromal TGFBI dystrophy that is characterized by recurrent erosions and irregular geographic opacification located_in the cornea, proteinaceous deposits in the anterior stroma and subepithelium, and progressive early vision loss, and has_material_basis in heterozygous mutation of transforming growth factor beta-induced gene located in chromosome 5q31.1, which encodes keratoepithelin. Abnormalities lead to increased protein deposition and disruption especially of Bowman's membrane of the cornea.", 
        "resource": "Disease Ontology", 
        "id": "DOID:0060453", 
        "name": "Reis-Bucklers corneal dystrophy"
    }, 
    "evidence": [
        {
            "url": "https://www.alliancegenome.org/gene/0060453#disease-associations", 
            "id": "0060453", 
            "database": "Alliance of Genome Resources"
        }
    ]
}