{
    "uniprot_canonical_ac": "A2CE44-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A2CE44-1|ZXDB_MOUSE Isoform 1 of Zinc finger X-linked protein ZXDB  OS=Mus musculus OX=10090 GN=Zxdb PE=1 SV=1 CANONICAL=A2CE44-1", 
        "length": 873, 
        "sequence": "MEIPRLLPARGTPQGAGGGGCPAGGGGVHRAPASLACQAPTRRLLLLRGAQDGGPGPRSAEAQRASRGLGPSLNRLAPRPDHRSSGGGRGGGAGGGGGGSGGGGGGGGGGGGGGGGGGSRGGSDDFFLLLLDPVGGDVETVGTEQAGAPVRREEAGAGPRPERRQSAGPPAGRPEPGPRCLSAVPAASPLPAAGPGPAAAAAAAAAAAFAGTITIHNQDLLLRFENGVLTLTTPPLPAWEPGVAPFPQPQPPPQPGALIAPQAAAAGFPPAAAAAAAAAAAGAQLGDCPELPPDLLLAEPAEPAACPAPPEEEAEAPAAAAAQSPRGPAGPGPGPGVVLYLCPEAQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLSGCGWTFTTSYKLKRHLQSHDKLRPFGCPVQGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEESFPTQAKLSTHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFACSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFDGCGWNFTSMSKLLRHKRKHEDDRRFTCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVEGCCARFSARSSLYIHSKKHLQDVGAWKSRCPVPTCNKLFTSKHSMKTHMTKRHNLSQDLLAQLEAANSLTPSSELTSPGQSDLSGAELVSLFSDVPGHGSAAVLDTALVNSGILTIDVASVNSSLAGSLPADNNSNNHSLGQAAEPRALRGAPSDLPQSLDTSLFFGTSVAGYQHSPLDMDDVSAGNVGLFGSLALKNSSLEPQALTPSNKLTVDTEALTPSSTLCENSVSELLTPAKAEWNVHPESDFFGHEEETQFGFSHPTGSHGSQKDTDLITVTGTPFLV"
    }, 
    "uniprot_id": "ZXDB_MOUSE", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2CE44", 
                    "id": "A2CE44", 
                    "database": "UniProtKB"
                }
            ], 
            "taxid": 10090, 
            "name": "Mus musculus"
        }
    ], 
    "crossref_internal": {
        "gene": [
            "Zxdb"
        ], 
        "species": [
            10090
        ]
    }, 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/18287559", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "18287559"
                }
            ], 
            "title": "GUDMAP: the genitourinary developmental molecular anatomy project.", 
            "journal": "Journal of the American Society of Nephrology : JASN", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074942.1", 
                    "id": "NP_001074942.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "McMahon AP, Aronow BJ, Davidson DR, Davies JA, Gaido KW, Grimmond S, Lessard JL, Little MH, Potter SS, Wilder EL, Zhang P", 
            "date": "2008"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/24129315", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "24129315"
                }
            ], 
            "title": "Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.", 
            "journal": "Mol. Cell. Proteomics", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2CE44", 
                    "id": "A2CE44", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Beausoleil S.A., Wang Y., Zhou J., Comb M.J., Guo A., Lee K.A., Aguiar M., Bedford M.T., Gu H., Jia X., Kornhauser J., Mulhern D., Ren J., Silva J.C., Vemulapalli V., Yang V.", 
            "date": "2014"
        }
    ], 
    "uniprot_ac": "A2CE44", 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2CE44", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Zxda"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2CE44", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Zxdb"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2CE44", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Zxdb"
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2CE44#A2CE44-1", 
            "isoform_ac": "A2CE44-1", 
            "locus": {
                "end_pos": 94724675, 
                "strand": "-", 
                "start_pos": 94727293, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000101388", 
                        "id": "ENSMUST00000101388", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000100524", 
                        "id": "ENSMUSP00000100524", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2CE44-1|ZXDB_MOUSE Isoform 1 of Zinc finger X-linked protein ZXDB  OS=Mus musculus OX=10090 GN=Zxdb PE=1 SV=1 CANONICAL=A2CE44-1", 
                "length": 873, 
                "sequence": "MEIPRLLPARGTPQGAGGGGCPAGGGGVHRAPASLACQAPTRRLLLLRGAQDGGPGPRSAEAQRASRGLGPSLNRLAPRPDHRSSGGGRGGGAGGGGGGSGGGGGGGGGGGGGGGGGGSRGGSDDFFLLLLDPVGGDVETVGTEQAGAPVRREEAGAGPRPERRQSAGPPAGRPEPGPRCLSAVPAASPLPAAGPGPAAAAAAAAAAAFAGTITIHNQDLLLRFENGVLTLTTPPLPAWEPGVAPFPQPQPPPQPGALIAPQAAAAGFPPAAAAAAAAAAAGAQLGDCPELPPDLLLAEPAEPAACPAPPEEEAEAPAAAAAQSPRGPAGPGPGPGVVLYLCPEAQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLSGCGWTFTTSYKLKRHLQSHDKLRPFGCPVQGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEESFPTQAKLSTHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFACSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFDGCGWNFTSMSKLLRHKRKHEDDRRFTCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVEGCCARFSARSSLYIHSKKHLQDVGAWKSRCPVPTCNKLFTSKHSMKTHMTKRHNLSQDLLAQLEAANSLTPSSELTSPGQSDLSGAELVSLFSDVPGHGSAAVLDTALVNSGILTIDVASVNSSLAGSLPADNNSNNHSLGQAAEPRALRGAPSDLPQSLDTSLFFGTSVAGYQHSPLDMDDVSAGNVGLFGSLALKNSSLEPQALTPSNKLTVDTEALTPSSTLCENSVSELLTPAKAEWNVHPESDFFGHEEETQFGFSHPTGSHGSQKDTDLITVTGTPFLV"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:668166", 
            "resource": "KEGG Pathway", 
            "id": "mmu:668166", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A2CE44#function", 
            "annotation": "Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2CE44#function", 
                    "id": "A2CE44", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "P98168-1", 
            "protein_name": "Zinc finger X-linked protein ZXDA", 
            "sequence": {
                "length": 799, 
                "sequence": "MEIPKLLPARGTLQGGGGGGIPAGGGRVHRGPDSPAGQVPTRRLLLPRGPQDGGPGRRREEASTASRGPGPSLFAPRPHQPSGGGDDFFLVLLDPVGGDVETAGSGQAAGPVLREEAKAGPGLQGDESGANPAGCSAQGPHCLSAVPTPAPISAPGPAAAFAGTVTIHNQDLLLRFENGVLTLATPPPHAWEPGAAPAQQPRCLIAPQAGFPQAAHPGDCPELRSDLLLAEPAEPAPAPAPQEEAEGLAAALGPRGLLGSGPGVVLYLCPEALCGQTFAKKHQLKMHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEESFPTQAKLGAHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFDGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVAGCCARFSARSSLYIHSKKHLQDVDTWKSRCPISSCNKLFTSKHSMKTHMVKRHKVGQDLLAQLEAANSLTPSSELTSQRQNDLSDAEIVSLFSDVPDSTSAALLDTALVNSGILTIDVASVSSTLAGHLPANNNNSVGQAVDPPSLMATSDPPQSLDTSLFFGTAATGFQQSSLNMDEVSSVSVGPLGSLDSLAMKNSSPEPQALTPSSKLTVDTDTLTPSSTLCENSVSELLTPAKAEWSVHPNSDFFGQEGETQFGFPNAAGNHGSQKERNLITVTGSSFLV"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A2CE44/", 
                    "id": "A2CE44", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "P98169-1", 
            "protein_name": "Zinc finger X-linked protein ZXDB", 
            "sequence": {
                "length": 803, 
                "sequence": "MEIPKLLPARGTLQGGGGGGIPAGGGRVHRGPDSPAGQVPTRRLLLLRGPQDGGPGRRREEASTASRGPGPSLLAPRTDQPSGGGGGGGDDFFLVLLDPVGGDVETAGSGQAAGPVLREEAEEGPGLQGGESGANPAGPTALGPRCLSAVPTPAPISAPGPAAAFAGTVTIHNQDLLLRFENGVLTLATPPPHAWEPGAAPAQQPGCLIAPQAGFPHAAHPGDCPELPPDLLLAEPAEPAPAPAPEEEAEGPAAALGPRGPLGSGPGVVLYLCPEAQCGQTFAKKHQLKVHLLTHSSSQGQRPFKCPLGGCGWTFTTSYKLKRHLQSHDKLRPFGCPAEGCGKSFTTVYNLKAHMKGHEQENSFKCEVCEESFPTQAKLSAHQRSHFEPERPYQCAFSGCKKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFLCDFDGCGWNFTSMSKLLRHKRKHDDDRRFMCPVEGCGKSFTRAEHLKGHSITHLGTKPFVCPVAGCCARFSARSSLYIHSKKHLQDVDTWKSRCPISSCNKLFTSKHSMKTHMVKRHKVGQDLLAQLEAANSLTPSSELTSQRQNDLSDAEIVSLFSDVPDSTSAALLDTALVNSGILTIDVASVSSTLAGHLPANNNNSVGQAVDPPSLMATSDPPQSLDTSLFFGTAATGFQQSSLNMDEVSSVSVGPLGSLDSLAMKNSSPEPQALTPSSKLTVDTDALTPSSTLCENSVSELLTPTKAEWNVHPDSDFFGQEGETQFGFPNAAGNHGSQKETDLITVTGSSFLV"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/21401", 
                    "id": "21401", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074942.1", 
        "ac": "NP_001074942.1", 
        "name": "zinc finger X-linked protein ZXDB", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2CE44", 
                                "id": "A2CE44", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "id": "GO:0003700", 
                        "name": "DNA-binding transcription factor activity"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2CE44", 
                                "id": "A2CE44", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "id": "GO:0046872", 
                        "name": "metal ion binding"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2CE44", 
                                "id": "A2CE44", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "id": "GO:0003676", 
                        "name": "nucleic acid binding"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070742", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2CE44", 
                                "id": "A2CE44", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "id": "GO:0070742", 
                        "name": "C2H2 zinc finger domain binding"
                    }
                ], 
                "total": 4, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2CE44", 
                                "id": "A2CE44", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "id": "GO:0005634", 
                        "name": "nucleus"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2CE44", 
                                "id": "A2CE44", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "id": "GO:0045893", 
                        "name": "positive regulation of transcription, DNA-templated"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "site_annotation": [
        {
            "end_pos": 535, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 533
        }, 
        {
            "end_pos": 644, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 642
        }, 
        {
            "end_pos": 712, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 710
        }, 
        {
            "end_pos": 723, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 721
        }, 
        {
            "end_pos": 727, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 725
        }, 
        {
            "end_pos": 788, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 786
        }
    ], 
    "pro_annotation": [], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000073062", 
            "id": "ENSMUSG00000073062", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/668166", 
            "id": "668166", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", 
            "id": "IPR013087", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", 
            "id": "IPR036236", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:668166", 
            "id": "mmu:668166", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:3694898", 
            "id": "3694898", 
            "database": "MGI"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/DWNVHPD/", 
            "id": "DWNVHPD", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=1318335at2759", 
            "id": "1318335at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00096", 
            "id": "PF00096", 
            "database": "Pfam"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2CE44", 
            "id": "PR_A2CE44", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074942.1", 
            "id": "NP_001074942.1", 
            "database": "RefSeq"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 90376.0, 
        "chemical_mass": 90376.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2CE44", 
            "name": "Zxdb", 
            "locus": {
                "end_pos": 94730187, 
                "strand": "+", 
                "start_pos": 94724569, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000073062", 
                        "id": "ENSMUSG00000073062", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2CE44", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Zinc finger X-linked protein ZXDB"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2CE44", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "zinc finger X-linked protein ZXDA/ZXDB"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2CE44", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "zinc finger X-linked protein ZXDB"
        }
    ]
}