{ "uniprot_canonical_ac": "A6H5Y3-1", "ptm_annotation": [], "sequence": { "header": "sp|A6H5Y3-1|METH_MOUSE Isoform 1 of Methionine synthase OS=Mus musculus OX=10090 GN=Mtr PE=1 SV=1 CANONICAL=A6H5Y3-1", "length": 1253, "sequence": "MKKTLQDEIEAILRKRIMVLDGGMGTMIQRYKLSEEHFQGQEFKDHSRPLKGNNDILSITQPDIIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNKCSADVARKAAEEITLQTGVKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVDAYQEQAKGLLDGRVDILLIETIFDTANAKAALFAIQNLFEENYAPPRPIFISGTIVDKSGRTLSGQTGEAFVTSVSHSDPLCIGLNCSLGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDETPSTMATHLKDFAVDGLVNIVGGCCGSTPDHIREIAEAVKKCKPRVPPASVFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALSIAKAQVEMGAQVLDINMDDGMLDGPSAMTRFCNSIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEGDFLEKARKIKKFGAAVVVMAFDEEGQATETDVKVNVCTRAYHLLVDKVGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATRVIKETLPGVRISGGLSNLSFSFRGMEAIREAMHGVFLYHAIKFGMDMGIVNAGNLPVYDAIHKDLLQLCEDLIWNKDSEATEKLLRYAQTHGTGGKKVIQTDEWRNGSIEERLEYALVKGIEKHIVEDTEEARLNGEKYPRPLNIIEGPLMNGMKVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREEARLINGSVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLACNNFRVIDLGVMTPCDKILQAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLRDDYFEEILEEYEDIRQDHYESLKERKYVPLSQARKHGFHIDWLSEPHPVKPTFIGTQVFEDYNLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKAVGEEARKVYNDAQNMLNILISQKKLQARGVVGFWPAQSVQDDIHLYAEGVVPQAAEPIATFYGLRQQAEKDSSSTDPYHCLSDFIAPLHSGVCDYLGLFAVACFGVEELSKTYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYSRSEQLGVPDLRRLRYEGIRPAPGYPSQPDHTEKLTMWRLASIEQATGIRLTESLAMAPASAVSGLYFSNVKAKYFAVGKISKDQTEDYALRKNMPVAEVEKWLGPILGYDTD" }, "uniprot_id": "METH_MOUSE", "enzyme_annotation": [ { "ec": "2.1.1.13", "activity": "" }, { "ec": "2.1.1.13", "activity": "5-methyltetrahydrofolate + L-homocysteine = tetrahydrofolate + L-methionine." } ], "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/9321480", "type": [ "PubMed" ], "id": "9321480" } ], "title": "The methionine synthase (Mtr) gene maps to proximal mouse chromosome 13.", "journal": "Mammalian genome : official journal of the International Mammalian Genome Society", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074597.1", "id": "NP_001074597.1", "database": "RefSeq" } ], "authors": "Zhang ZX, Leclerc D, Gravel R, Rozen R", "date": "1997" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/22365888", "type": [ "PubMed" ], "id": "22365888" } ], "title": "Spatial and temporal expression of folate-related transporters and metabolic enzymes during mouse placental development.", "journal": "Placenta", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074597.1", "id": "NP_001074597.1", "database": "RefSeq" } ], "authors": "Cherukad J, Wainwright V, Watson ED", "date": "2012" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/16963246", "type": [ "PubMed" ], "id": "16963246" } ], "title": "Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice.", "journal": "The Journal of nutritional biochemistry", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074597.1", "id": "NP_001074597.1", "database": "RefSeq" } ], "authors": "Lawrance AK, Deng L, Brody LC, Finnell RH, Shane B, Rozen R", "date": "2007" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/12520002", "type": [ "PubMed" ], "id": "12520002" } ], "title": "BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.", "journal": "Nucleic acids research", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074597.1", "id": "NP_001074597.1", "database": "RefSeq" } ], "authors": "Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE", "date": "2003" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/11110696", "type": [ "PubMed" ], "id": "11110696" } ], "title": "Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent mechanism.", "journal": "Blood", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074597.1", "id": "NP_001074597.1", "database": "RefSeq" } ], "authors": "Gwynn B, Ciciotte SL, Hunter SJ, Washburn LL, Smith RS, Andersen SG, Swank RT, Dell'Angelica EC, Bonifacino JS, Eicher EM, Peters LL", "date": "2000" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/11440986", "type": [ "PubMed" ], "id": "11440986" } ], "title": "Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy.", "journal": "Human molecular genetics", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074597.1", "id": "NP_001074597.1", "database": "RefSeq" } ], "authors": "Mills M, Yang N, Weinberger R, Vander Woude DL, Beggs AH, Easteal S, North K", "date": "2001" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/17937387", "type": [ "PubMed" ], "id": "17937387" } ], "title": "Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver.", "journal": "Hepatology (Baltimore, Md.)", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074597.1", "id": "NP_001074597.1", "database": "RefSeq" } ], "authors": "Liu SP, Li YS, Chen YJ, Chiang EP, Li AF, Lee YH, Tsai TF, Hsiao M, Huang SF, Chen YM", "date": "2007" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/19158324", "type": [ "PubMed" ], "id": "19158324" } ], "title": "Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1alpha.", "journal": "American journal of physiology. Endocrinology and metabolism", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074597.1", "id": "NP_001074597.1", "database": "RefSeq" } ], "authors": "Li S, Arning E, Liu C, Vitvitsky V, Hernandez C, Banerjee R, Bottiglieri T, Lin JD", "date": "2009" } ], "uniprot_ac": "A6H5Y3", "site_annotation": [ { "end_pos": 752, "annotation": "n_glycosylation_sequon", "start_pos": 750 }, { "end_pos": 249, "annotation": "n_glycosylation_sequon", "start_pos": 247 }, { "end_pos": 569, "annotation": "n_glycosylation_sequon", "start_pos": 567 }, { "end_pos": 155, "annotation": "n_glycosylation_sequon", "start_pos": 153 }, { "end_pos": 139, "annotation": "n_glycosylation_sequon", "start_pos": 137 }, { "end_pos": 658, "annotation": "n_glycosylation_sequon", "start_pos": 656 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3#A0A1Y7VM88-1", "isoform_ac": "A0A1Y7VM88-1", "locus": { "end_pos": 12241658, "strand": "+", "start_pos": 12253973, "chromosome": "13", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000221290", "id": "ENSMUST00000221290", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000152579", "id": "ENSMUSP00000152579", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A1Y7VM88-1|METH_MOUSE Computationally mapped isoform of Methionine synthase OS=Mus musculus OX=10090 GN=Mtr PE=1 SV=1 CANONICAL=A6H5Y3-1", "length": 222, "sequence": "MKKTLQDEIEAILRKRIMVLDGGMGTMIQRYKLSEEHFQGQEFKDHSRPLKGNNDILSITQPDIIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLESRGLWLELWVRLIRHFLSPHLWKGQIIGTSHLMSLLTHTRSRPRDCWMAGSTSYSLKQFLIQLMPKQPCLRSRTSLKRIMLLLGLSLFLGPLLIKVEGLFLGRRERLLSPACLIRTPCALD" } }, { "url": "https://www.uniprot.org/uniprot/A6H5Y3#A6H5Y3-1", "isoform_ac": "A6H5Y3-1", "locus": { "end_pos": 12187008, "strand": "+", "start_pos": 12253973, "chromosome": "13", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000099856", "id": "ENSMUST00000099856", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000097442", "id": "ENSMUSP00000097442", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A6H5Y3-1|METH_MOUSE Isoform 1 of Methionine synthase OS=Mus musculus OX=10090 GN=Mtr PE=1 SV=1 CANONICAL=A6H5Y3-1", "length": 1253, "sequence": "MKKTLQDEIEAILRKRIMVLDGGMGTMIQRYKLSEEHFQGQEFKDHSRPLKGNNDILSITQPDIIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNKCSADVARKAAEEITLQTGVKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVDAYQEQAKGLLDGRVDILLIETIFDTANAKAALFAIQNLFEENYAPPRPIFISGTIVDKSGRTLSGQTGEAFVTSVSHSDPLCIGLNCSLGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDETPSTMATHLKDFAVDGLVNIVGGCCGSTPDHIREIAEAVKKCKPRVPPASVFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALSIAKAQVEMGAQVLDINMDDGMLDGPSAMTRFCNSIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEGDFLEKARKIKKFGAAVVVMAFDEEGQATETDVKVNVCTRAYHLLVDKVGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATRVIKETLPGVRISGGLSNLSFSFRGMEAIREAMHGVFLYHAIKFGMDMGIVNAGNLPVYDAIHKDLLQLCEDLIWNKDSEATEKLLRYAQTHGTGGKKVIQTDEWRNGSIEERLEYALVKGIEKHIVEDTEEARLNGEKYPRPLNIIEGPLMNGMKVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREEARLINGSVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLACNNFRVIDLGVMTPCDKILQAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLRDDYFEEILEEYEDIRQDHYESLKERKYVPLSQARKHGFHIDWLSEPHPVKPTFIGTQVFEDYNLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKAVGEEARKVYNDAQNMLNILISQKKLQARGVVGFWPAQSVQDDIHLYAEGVVPQAAEPIATFYGLRQQAEKDSSSTDPYHCLSDFIAPLHSGVCDYLGLFAVACFGVEELSKTYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYSRSEQLGVPDLRRLRYEGIRPAPGYPSQPDHTEKLTMWRLASIEQATGIRLTESLAMAPASAVSGLYFSNVKAKYFAVGKISKDQTEDYALRKNMPVAEVEKWLGPILGYDTD" } } ], "pathway": [ { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-156581", "resource": "Reactome", "id": "R-MMU-156581", "name": "Methylation" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-1614635", "resource": "Reactome", "id": "R-MMU-1614635", "name": "Sulfur amino acid metabolism" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-196741", "resource": "Reactome", "id": "R-MMU-196741", "name": "Cobalamin (Cbl, vitamin B12) transport and metabolism" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:238505", "resource": "KEGG Pathway", "id": "mmu:238505", "name": "" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3#function", "annotation": "Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (By similarity).", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3#function", "id": "A6H5Y3", "database": "UniProtKB" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q99707-1", "protein_name": "Methionine synthase", "sequence": { "length": 1265, "sequence": "MSPALQDLSQPEGLKKTLRDEINAILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNMCSAGVARKAAEEVTLQTGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGTIVDKSGRTLSGQTGEGFVISVSHGEPLCIGLNCALGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYDETPSMMAKHLKDFAMDGLVNIVGGCCGSTPDHIREIAEAVKNCKPRVPPATAFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSRKFAKLIMAGNYEEALCVAKVQVEMGAQVLDVNMDDGMLDGPSAMTRFCNLIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEDDFLEKARKIKKYGAAMVVMAFDEEGQATETDTKIRVCTRAYHLLVKKLGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATKVIKETLPGARISGGLSNLSFSFRGMEAIREAMHGVFLYHAIKSGMDMGIVNAGNLPVYDDIHKELLQLCEDLIWNKDPEATEKLLRYAQTQGTGGKKVIQTDEWRNGPVEERLEYALVKGIEKHIIEDTEEARLNQKKYPRPLNIIEGPLMNGMKIVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREETRVLNGTVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILKAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIRIPLLIGGATTSKTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDEYFEEIMEEYEDIRQDHYESLKERRYLPLSQARKSGFQMDWLSEPHPVKPTFIGTQVFEDYDLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKTVGGEARKVYDDAHNMLNTLISQKKLRARGVVGFWPAQSIQDDIHLYAEAAVPQAAEPIATFYGLRQQAEKDSASTEPYYCLSDFIAPLHSGIRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLDVADLRRLRYKGIRPAPGYPSQPDHTEKLTMWRLADIEQSTGIRLTESLAMAPASAVSGLYFSNLKSKYFAVGKISKDQVEDYALRKNISVAEVEKWLGPILGYDTD" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/37280", "id": "37280", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A6H5Y3/", "id": "A6H5Y3", "database": "OMA" } ], "common_name": "Human", "organism": "Homo sapiens", "tax_id": 9606 }, { "uniprot_canonical_ac": "Q9Z2Q4-1", "protein_name": "Methionine synthase", "sequence": { "length": 1253, "sequence": "MKKTLQDEIEAILRKRIMVLDGGMGTMIQRYKLSEENFQGQEFKDHSRPLKGNNDILSITQPDVIYQIHKEYLLAGADIIETNTFSSTSIAQADYGLEHLAYRMNKCSADVARKAAEEITLQTGVKRFVAGSLGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQKLFEENYASPRPIFISGTIVDKSGRTLSGQTGEAFVTSVSHSDPLCIGLNCALGAAEMRPFIETIGKCTTAYVLCYPNAGLPNTFGDYDETPAMMAMHLKDFAVDGLVNVVGGCCGSTPDHIREIAEAVKNCKPRVPPDSVFEGHMLLSGLEPFRIGPYTNFVNIGERCNVAGSKKFAKLIMAGNYEEALSVAKVQVEMGAQVLDINMDDGMLDGPSAMTKFCNFIASEPDIAKVPLCIDSSNFAVIEAGLKCCQGKCIVNSISLKEGEEDFLEKARKIKKFGAAVVVMAFDEEGQATETDVKVSVCTRAYHLLVEKVGFNPNDIIFDPNILTIGTGMEEHNLYAINFIHATRVIKETLPGVRISGGLSNLSFAFRGMDAIREAMHGVFLYHAIKFGMDMGIVNAGSLPVYDDIHKDLLQLCEDLIWNRDAEATEKLLRYAQTHGKGGKKVIQTDEWRNGSIEERLEYALVKGIEKHIVEDTEEARLNREKYPRPLNIIEGPLMNGMKVVGDLFGAGKMFLPQVIKSARVMKKAVGHLIPFMEKEREEARVLNGSVEEEDPYQGTIVLATVKGDVHDIGKNIVGVVLGCNNFRVIDLGVMTPCDKILQAALDHKADIIGLSGLITPSLDEMIFVAKEMERLAIKIPLLIGGATTSRTHTAVKIAPRYSAPVIHVLDASKSVVVCSQLLDENLKDDYFEEILEEYEDIRQDHYESLKERKYLPLSQARKHSFHIDWLSEPHPVKPTFIGTQVFEDYNLQKLVDYIDWKPFFDVWQLRGKYPNRGFPKIFNDKAVGEEARKVYEDAQNMLSILISRKKLRARGVVGFWPAQSVQDDIHLYAEGAVPQAAEPIATFYGLRQQAEKDSSSTDPYHCLSDFVAPLHSGVRDYLGLFAVACFGVEELSKAYEDDGDDYSSIMVKALGDRLAEAFAEELHERVRRELWAYCGSEQLGVTDLRKLRYEGIRPAPGYPSQPDHTEKLTMWRLANIEQATGIRLTESLAMAPASAVSGLYFSNVKSKYFAVGKISKDQIEDYALRKNMSVAEVEKWLGPILGYDTD" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/37280", "id": "37280", "database": "MGI" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "tax_id": 10116 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074597.1", "ac": "NP_001074597.1", "name": "methionine synthase", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008705", "pmid": "11158293", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "methionine synthase activity", "id": "GO:0008705" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "zinc ion binding", "id": "GO:0008270" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016597", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "amino acid binding", "id": "GO:0016597" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "methyltransferase activity", "id": "GO:0008168" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005542", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "folic acid binding", "id": "GO:0005542" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031419", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "cobalamin binding", "id": "GO:0031419" } ], "total": 6, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "cytosol", "id": "GO:0005829" } ], "total": 1, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009086", "pmid": "11158293", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "methionine biosynthetic process", "id": "GO:0009086" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009235", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "cobalamin metabolic process", "id": "GO:0009235" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006479", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "protein methylation", "id": "GO:0006479" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048678", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "response to axon injury", "id": "GO:0048678" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071732", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "cellular response to nitric oxide", "id": "GO:0071732" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031103", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", "id": "A6H5Y3", "database": "UniProtKB" } ], "name": "axon regeneration", "id": "GO:0031103" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046653", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A6H5Y3", 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