{ "uniprot_canonical_ac": "A4F267-1", "ptm_annotation": [], "sequence": { "header": "sp|A4F267-1|TM40L_RAT Isoform 1 of Mitochondrial import receptor subunit TOM40B OS=Rattus norvegicus OX=10116 GN=Tomm40l PE=1 SV=1 CANONICAL=A4F267-1", "length": 308, "sequence": "MGNTLGLAPMGTLPRWSHRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTVHMSALGLPGYHLHTAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSITHRLVLGGELVYHRRPGEEGAILTLAGKYSALHWVATLNVGSGGAHASYYHKANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQADMVFRGLVDSNWCVGAVLEKKMRPLPVTLALGAFLNHWRNRFHCGFSITVG" }, "uniprot_id": "TM40L_RAT", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Rat", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4F267", "id": "A4F267", "database": "UniProtKB" } ], "name": "Rattus norvegicus", "taxid": 10116 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/17437969", "type": [ "PubMed" ], "id": "17437969" } ], "title": "Identification and characterization of a new Tom40 isoform, a central component of mitochondrial outer membrane translocase.", "journal": "J. Biochem.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4F267", "id": "A4F267", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076807.1", "id": "NP_001076807.1", "database": "RefSeq" } ], "authors": "Oka T., Mihara K., Kinoshita J.Y.", "date": "2007" } ], "uniprot_ac": "A4F267", "site_annotation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A4F267#A4F267-1", "isoform_ac": "A4F267-1", "locus": { "end_pos": 89591920, "strand": "+", "start_pos": 89594606, "chromosome": "13", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOT00000004641", "id": "ENSRNOT00000004641", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSRNOP00000004641", "id": "ENSRNOP00000004641", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A4F267-1|TM40L_RAT Isoform 1 of Mitochondrial import receptor subunit TOM40B OS=Rattus norvegicus OX=10116 GN=Tomm40l PE=1 SV=1 CANONICAL=A4F267-1", "length": 308, "sequence": "MGNTLGLAPMGTLPRWSHRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTVHMSALGLPGYHLHTAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSITHRLVLGGELVYHRRPGEEGAILTLAGKYSALHWVATLNVGSGGAHASYYHKANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQADMVFRGLVDSNWCVGAVLEKKMRPLPVTLALGAFLNHWRNRFHCGFSITVG" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:304971", "resource": "KEGG Pathway", "id": "rno:304971", "name": "" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A4F267#function", "annotation": "Potential channel-forming protein implicated in import of protein precursors into mitochondria.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4F267#function", "id": "A4F267", "database": "UniProtKB" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q969M1-1", "protein_name": "Mitochondrial import receptor subunit TOM40B", "sequence": { "length": 308, "sequence": "MGNTLGLAPMGTLPRRSPRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTIHMSALGLPGYHLHAAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSLTHRLVLGGELVYHRRPGEEGAILTLAGKYSAVHWVATLNVGSGGAHASYYHRANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQANMVFRGLVDSNWCVGAVLEKKMPPLPVTLALGAFLNHWRNRFHCGFSITVG" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/134180", "id": "134180", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "tax_id": 9606 }, { "uniprot_canonical_ac": "Q9CZR3-1", "protein_name": "Mitochondrial import receptor subunit TOM40B", "sequence": { "length": 308, "sequence": "MGNTLGLAPMGTLPRRSHRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTVHMSALGLPGYHLHTAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSITHRLVLGGELVYHRRPGEEGAILTLAGKYSAVHWVATLNVGSGGAHASYYHKANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQADMVFRGLVDSNWCVGAVLEKKMRPLPVTLALGAFLNHWRNRFHCGFSITVG" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/134180", "id": "134180", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A4F267/", "id": "A4F267", "database": "OMA" } ], "common_name": "Mouse", "organism": "Mus musculus", "tax_id": 10090 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076807.1", "ac": "NP_001076807.1", "name": "mitochondrial import receptor subunit TOM40B", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070678", "pmid": "17437969", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4F267", "id": "A4F267", "database": "UniProtKB" } ], "name": "preprotein binding", "id": "GO:0070678" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008320", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4F267", "id": "A4F267", "database": "UniProtKB" } ], "name": "protein transmembrane transporter activity", "id": "GO:0008320" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030943", "pmid": "17437969", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4F267", "id": "A4F267", "database": "UniProtKB" } ], "name": "mitochondrion targeting sequence binding", "id": "GO:0030943" } ], "total": 3, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005742", "pmid": "17437969", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4F267", "id": "A4F267", "database": "UniProtKB" } ], "name": "mitochondrial outer membrane translocase complex", "id": "GO:0005742" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4F267", "id": "A4F267", "database": "UniProtKB" } ], "name": "integral component of membrane", "id": "GO:0016021" } ], "total": 2, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030150", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4F267", "id": "A4F267", "database": "UniProtKB" } ], "name": "protein import into mitochondrial matrix", "id": "GO:0030150" } ], "total": 1, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A4F267", "type": "synonym", "resource": "RefSeq", "name": "RGD1562006; Tomm40b" }, { "url": "https://www.uniprot.org/uniprot/A4F267", "type": "synonym", "resource": "UniProtKB", "name": "Tomm40b" }, { "url": "https://www.uniprot.org/uniprot/A4F267", "type": "recommended", "resource": "UniProtKB", "name": "Tomm40l" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A4F267", "type": "synonym", "resource": "RefSeq", "name": "Tomm40l" } ], "crossref": [ { "url": "https://www.ncbi.nlm.nih.gov/gene/304971", "id": "304971", "database": "GeneID" }, { "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A4F267", "id": "PR_A4F267", "database": "PRO" }, { "url": "http://www.orthodb.org/?query=1346842at2759", "id": "1346842at2759", "database": "OrthoDB" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07305", "id": "cd07305", "database": "CDD" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000003398", "id": "ENSRNOG00000003398", "database": "Bgee" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR027246", "id": "IPR027246", "database": "InterPro" }, { "url": "https://omabrowser.org/oma/group/MNLPCPV/", "id": "MNLPCPV", "database": "OMA" }, { "url": "http://pfam.xfam.org/family/PF01459", "id": "PF01459", "database": "Pfam" }, { "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1562006", "id": "1562006", "database": "RGD" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR037930", "id": "IPR037930", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:304971", "id": "rno:304971", "database": "KEGG Pathway" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076807.1", "id": "NP_001076807.1", "database": "RefSeq" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR023614", "id": "IPR023614", "database": "InterPro" }, { "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10802", "id": "PTHR10802", "database": "PANTHER" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 34049.0, "chemical_mass": 34049.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A4F267", "name": "Tomm40l", "locus": { "end_pos": 89591718, "strand": "-", "start_pos": 89594738, "chromosome": "13", "evidence": [ { "url": "https://www.ensembl.org/id/ENSRNOG00000003398", "id": "ENSRNOG00000003398", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A4F267", "type": "recommended", "resource": "UniProtKB", "name": "Mitochondrial import receptor subunit TOM40B" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A4F267", "type": "synonym", "resource": "RefSeq", "name": "mitochondrial import receptor subunit TOM40B" }, { "url": "https://www.uniprot.org/uniprot/A4F267", "type": "synonym", "resource": "UniProtKB", "name": "Protein TOMM40-like" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A4F267", "type": "synonym", "resource": "RefSeq", "name": "translocase of outer mitochondrial membrane 40 homolog B; translocase of outer mitochondrial membrane 40 homolog-like" } ] }