{
    "uniprot_canonical_ac": "A2ATU0-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A2ATU0-1|DHTK1_MOUSE Isoform 1 of Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial  OS=Mus musculus OX=10090 GN=Dhtkd1 PE=1 SV=1 CANONICAL=A2ATU0-1", 
        "length": 921, 
        "sequence": "MASAATVAAAGRALRRAVLLLRRGYQTERGVYGYRPRKAKSGEPRGDRARPSVDHGLARLVTVYCEHGHKAAQINPLFPGQALLDTVPEIQALVRTLQGPFTTTGLLNLGKEAASLEEVLAYLNHIYCGPISIETAQLQSQEERDWFARRFEELKKETFTTEERKYLSKLLLESQEFDHFLATKFATVKRYGGEGAESMMGFFHELLKLSAYGGITDIIIGMPHRGRLNLLTGLLQLPPELMFRKMRGLSEFPENVATIGDVLSHLTSSVDLDFGAHQPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSREDGDYSPNGSAQPGDKVICLQVHGDASFCGQGIVLETFTLSNLPHFRIGGSIHLIVNNQLGYTTPAERGRSSLYSSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIVDLLCYRQWGHNELDEPFFTNPVMYKIIRARKSIPDTYAEHLIASGLMTQEEVSDIKTSYYTKLNDHLANVAHYSPPATNLQARWQGLVQPEACVTTWDTGVPLELLRFIGVKSVEVPEELQVHSHLLKMYVQSRMEKVKNGSGLDWATAETLALGSLLAQGFNVRLSGQDVGRGTFSQRHAMVVCQDTDDAYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPTLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGLVILLPHGYDGAGPEHSSCRIERFLQMCDSAEEGVDSDTVNMFVVHPTTPAQYFHLLRRQMIRNFRKPLIVASPKMLLRYPAAVSTLEEMAPGTAFKPVIGDSSVDPKNVKTLIFCSGKHFYALLKQRESLGTKKHDFAIIRLEELCPFPLDALQQEMSKYKHVRDVIWSQEEPQNMGPWSFVSPRFEKQLACRLRLVSRPPLPAPAVGIGTVHQQQHEDILSKTFTQ"
    }, 
    "uniprot_id": "DHTK1_MOUSE", 
    "enzyme_annotation": [
        {
            "ec": "1.2.4.2", 
            "activity": "2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine = [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO(2)."
        }, 
        {
            "ec": "1.2.4.2", 
            "activity": ""
        }
    ], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2ATU0", 
                    "id": "A2ATU0", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/23806337", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "23806337"
                }
            ], 
            "title": "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.", 
            "journal": "Mol. Cell", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2ATU0", 
                    "id": "A2ATU0", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Chen Y., Park J., Zhang Y., Zhao Y., Peng C., Tan M., Xie Z., Zwaans B.M., Lombard D.B., Dai L., Tishkoff D.X., Skinner M.E.", 
            "date": "2013"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/28545977", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "28545977"
                }
            ], 
            "title": "Elevated glutaric acid levels in Dhtkd1-/Gcdh- double knockout mice challenge our current understanding of lysine metabolism.", 
            "journal": "Biochimica et biophysica acta. Molecular basis of disease", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074600.1", 
                    "id": "NP_001074600.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Biagosch C, Ediga RD, Hensler SV, Faerberboeck M, Kuehn R, Wurst W, Meitinger T, Kolker S, Sauer S, Prokisch H", 
            "date": "2017"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/12520002", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "12520002"
                }
            ], 
            "title": "BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.", 
            "journal": "Nucleic acids research", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074600.1", 
                    "id": "NP_001074600.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE", 
            "date": "2003"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/25215496", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "25215496"
                }
            ], 
            "title": "Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population.", 
            "journal": "Cell", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074600.1", 
                    "id": "NP_001074600.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Wu Y, Williams EG, Dubuis S, Mottis A, Jovaisaite V, Houten SM, Argmann CA, Faridi P, Wolski W, Kutalik Z, Zamboni N, Auwerx J, Aebersold R", 
            "date": "2014"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/29661920", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "29661920"
                }
            ], 
            "title": "DHTKD1 Deficiency Causes Charcot-Marie-Tooth Disease in Mice.", 
            "journal": "Molecular and cellular biology", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074600.1", 
                    "id": "NP_001074600.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Xu WY, Zhu H, Shen Y, Wan YH, Tu XD, Wu WT, Tang L, Zhang HX, Lu SY, Jin XL, Fei J, Wang ZG", 
            "date": "2018"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/24029230", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "24029230"
                }
            ], 
            "title": "Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.", 
            "journal": "Cancer cell", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074600.1", 
                    "id": "NP_001074600.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Nagamachi A, Matsui H, Asou H, Ozaki Y, Aki D, Kanai A, Takubo K, Suda T, Nakamura T, Wolff L, Honda H, Inaba T", 
            "date": "2013"
        }
    ], 
    "uniprot_ac": "A2ATU0", 
    "site_annotation": [
        {
            "end_pos": 319, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 317
        }, 
        {
            "end_pos": 568, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 566
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2ATU0#A2ATU0-1", 
            "isoform_ac": "A2ATU0-1", 
            "locus": {
                "end_pos": 5898711, 
                "strand": "+", 
                "start_pos": 5942671, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000026924", 
                        "id": "ENSMUST00000026924", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000026924", 
                        "id": "ENSMUSP00000026924", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2ATU0-1|DHTK1_MOUSE Isoform 1 of Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial  OS=Mus musculus OX=10090 GN=Dhtkd1 PE=1 SV=1 CANONICAL=A2ATU0-1", 
                "length": 921, 
                "sequence": "MASAATVAAAGRALRRAVLLLRRGYQTERGVYGYRPRKAKSGEPRGDRARPSVDHGLARLVTVYCEHGHKAAQINPLFPGQALLDTVPEIQALVRTLQGPFTTTGLLNLGKEAASLEEVLAYLNHIYCGPISIETAQLQSQEERDWFARRFEELKKETFTTEERKYLSKLLLESQEFDHFLATKFATVKRYGGEGAESMMGFFHELLKLSAYGGITDIIIGMPHRGRLNLLTGLLQLPPELMFRKMRGLSEFPENVATIGDVLSHLTSSVDLDFGAHQPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSREDGDYSPNGSAQPGDKVICLQVHGDASFCGQGIVLETFTLSNLPHFRIGGSIHLIVNNQLGYTTPAERGRSSLYSSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIVDLLCYRQWGHNELDEPFFTNPVMYKIIRARKSIPDTYAEHLIASGLMTQEEVSDIKTSYYTKLNDHLANVAHYSPPATNLQARWQGLVQPEACVTTWDTGVPLELLRFIGVKSVEVPEELQVHSHLLKMYVQSRMEKVKNGSGLDWATAETLALGSLLAQGFNVRLSGQDVGRGTFSQRHAMVVCQDTDDAYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPTLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGLVILLPHGYDGAGPEHSSCRIERFLQMCDSAEEGVDSDTVNMFVVHPTTPAQYFHLLRRQMIRNFRKPLIVASPKMLLRYPAAVSTLEEMAPGTAFKPVIGDSSVDPKNVKTLIFCSGKHFYALLKQRESLGTKKHDFAIIRLEELCPFPLDALQQEMSKYKHVRDVIWSQEEPQNMGPWSFVSPRFEKQLACRLRLVSRPPLPAPAVGIGTVHQQQHEDILSKTFTQ"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-389661", 
            "resource": "Reactome", 
            "id": "R-MMU-389661", 
            "name": "Glyoxylate metabolism and glycine degradation"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:209692", 
            "resource": "KEGG Pathway", 
            "id": "mmu:209692", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074600.1", 
            "annotation": "In the BXD mouse population, natural variants in Dhtkd1 lead to changes in metabolite levels of 2-aminoadipate and in turn are associated with diabetes status, independently of chow or high fat diet feeding.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074600.1", 
                    "id": "NP_001074600.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2ATU0#function", 
            "annotation": "The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2ATU0#function", 
                    "id": "A2ATU0", 
                    "database": "UniProtKB"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074600.1", 
            "annotation": "Elevated glutaric acid levels in Dhtkd1-/Gcdh- double knockout mice challenge our current understanding of lysine metabolism.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074600.1", 
                    "id": "NP_001074600.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074600.1", 
            "annotation": "Dhtkd1(-/-) mice mimic the major aspects of CMT2 phenotypes, characterized by progressive weakness and atrophy in the distal parts of limbs with motor and sensory dysfunctions, which are accompanied with decreased nerve conduction velocity. Moreover, DHTKD1 deficiency causes severe metabolic abnormalities and dramatically increased levels of 2-ketoadipic acid (2-KAA) and 2-aminoadipic acid (2-AAA) in urine. Publication Status: Online-Only", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074600.1", 
                    "id": "NP_001074600.1", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q4KLP0-1", 
            "protein_name": "Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial", 
            "sequence": {
                "length": 920, 
                "sequence": "MASATVAAAGRALRRAVPLLRRSYQTERGVYGYRPRKAGSGEPRGDRARPSVDHGLARLVTVYCEHGHKAAQINPLFPGQALLDTVPEIQALVQTLQGPFTTTGLLNMGKEEASLEEVLAYLNHIYCGPISIETAQLQSQEEKDWFARRFEELKKETFTTEERKHLSKLLLESQEFDHFLATKFATVKRYGGEGAESMMGFFHELLKLSAYGGITDIIIGMPHRGRLNLLTGLLQLPPELMFRKMRGLSEFPENVAAIGDVLSHLTSSVDLDFGAHRPLHVTMLPNPSHLEAINPVAVGKTRGRQQSQEDGDYSPNGSAQPGDKVICLQVHGDASFCGQGIVLETFTLSNLPHFRIGGSIHLIVNNQLGYTTPAERGRSSLYSSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFFTNPVMYKIIRARKSIPDTYAEHLIASGLMTQEEVSDIKASYYAKLNGHLANVAHYSPPAPHLQARWQGLVQPAACVTTWDTGVPLELLRFVGVKSVEVPEELQLHSHLLKMYVQSRMEKVKNGTNLDWATAETLALGSLLAQGFNVRLSGQDVGRGTFSQRHAMVVCQNTDDVYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGLVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDSDTVNMFVVHPTTPAQYFHLLRRQMMRNFRKPLIVASPKMLLRYPVAVSTLEEMAPGTAFKPVIGDSSVDPKNVKTLIFCSGKHFYALLKQRESLGAKKRDFAIIRLEELCPFPLDSLQQEMGKYKHVQDIIWSQEEPQNMGPWSFVYPRFEKQLACKLRLVSRPPLPAPAVGIGTVHQQQHEAILFKTFTS"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A2ATU0/", 
                    "id": "A2ATU0", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/10278", 
                    "id": "10278", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Rat", 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }, 
        {
            "uniprot_canonical_ac": "Q96HY7-1", 
            "protein_name": "Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial", 
            "sequence": {
                "length": 919, 
                "sequence": "MASATAAAARRGLGRALPLFWRGYQTERGVYGYRPRKPESREPQGALERPPVDHGLARLVTVYCEHGHKAAKINPLFTGQALLENVPEIQALVQTLQGPFHTAGLLNMGKEEASLEEVLVYLNQIYCGQISIETSQLQSQDEKDWFAKRFEELQKETFTTEERKHLSKLMLESQEFDHFLATKFSTVKRYGGEGAESMMGFFHELLKMSAYSGITDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENFSATGDVLSHLTSSVDLYFGAHHPLHVTMLPNPSHLEAVNPVAVGKTRGRQQSRQDGDYSPDNSAQPGDRVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFYTNPIMYKIIRARKSIPDTYAEHLIAGGLMTQEEVSEIKSSYYAKLNDHLNNMAHYRPPALNLQAHWQGLAQPEAQITTWSTGVPLDLLRFVGMKSVEVPRELQMHSHLLKTHVQSRMEKMMDGIKLDWATAEALALGSLLAQGFNVRLSGQDVGRGTFSQRHAIVVCQETDDTYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDGDTVNMFVVHPTTPAQYFHLLRRQMVRNFRKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVIGDSSVDPKKVKTLVFCSGKHFYSLVKQRESLGAKKHDFAIIRVEELCPFPLDSLQQEMSKYKHVKDHIWSQEEPQNMGPWSFVSPRFEKQLACKLRLVGRPPLPVPAVGIGTVHLHQHEDILAKTFA"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A2ATU0/", 
                    "id": "A2ATU0", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/10278", 
                    "id": "10278", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074600.1", 
        "ac": "NP_001074600.1", 
        "name": "probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004591", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2ATU0", 
                                "id": "A2ATU0", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "oxoglutarate dehydrogenase (succinyl-transferring) activity", 
                        "id": "GO:0004591"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030976", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2ATU0", 
                                "id": "A2ATU0", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "thiamine pyrophosphate binding", 
                        "id": "GO:0030976"
                    }
                ], 
                "total": 2, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2ATU0", 
                                "id": "A2ATU0", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytosol", 
                        "id": "GO:0005829"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045252", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2ATU0", 
                                "id": "A2ATU0", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "oxoglutarate dehydrogenase complex", 
                        "id": "GO:0045252"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2ATU0", 
                                "id": "A2ATU0", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "mitochondrion", 
                        "id": "GO:0005739"
                    }
                ], 
                "total": 3, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006099", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2ATU0", 
                                "id": "A2ATU0", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "tricarboxylic acid cycle", 
                        "id": "GO:0006099"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002244", 
                        "pmid": "24029230", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2ATU0", 
                                "id": "A2ATU0", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "hematopoietic progenitor cell differentiation", 
                        "id": "GO:0002244"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006091", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2ATU0", 
                                "id": "A2ATU0", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "generation of precursor metabolites and energy", 
                        "id": "GO:0006091"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006096", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2ATU0", 
                                "id": "A2ATU0", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "glycolytic process", 
                        "id": "GO:0006096"
                    }
                ], 
                "total": 4, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2ATU0", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Dhtkd1"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2ATU0", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "C330018I04Rik"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2ATU0", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Kiaa1630"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2ATU0", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Dhtkd1"
        }
    ], 
    "crossref": [
        {
            "url": "http://pfam.xfam.org/family/PF02779", 
            "id": "PF02779", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A2ATU0*", 
            "id": "A2ATU0", 
            "database": "IntAct"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00676", 
            "id": "PF00676", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:2445096", 
            "id": "2445096", 
            "database": "MGI"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:209692", 
            "id": "mmu:209692", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-389661", 
            "id": "R-MMU-389661", 
            "database": "Reactome"
        }, 
        {
            "url": "http://www.orthodb.org/?query=134699at2759", 
            "id": "134699at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/FEYGMAI/", 
            "id": "FEYGMAI", 
            "database": "OMA"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074600.1", 
            "id": "NP_001074600.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR005475", 
            "id": "IPR005475", 
            "database": "InterPro"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000025815", 
            "id": "ENSMUSG00000025815", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029061", 
            "id": "IPR029061", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011603", 
            "id": "IPR011603", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001017", 
            "id": "IPR001017", 
            "database": "InterPro"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2ATU0", 
            "id": "PR_A2ATU0", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/209692", 
            "id": "209692", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR042179", 
            "id": "IPR042179", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF16870", 
            "id": "PF16870", 
            "database": "Pfam"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR031717", 
            "id": "IPR031717", 
            "database": "InterPro"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23152", 
            "id": "PTHR23152", 
            "database": "PANTHER"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 102793.0, 
        "chemical_mass": 102793.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2ATU0", 
            "name": "Dhtkd1", 
            "locus": {
                "end_pos": 5896115, 
                "strand": "-", 
                "start_pos": 5942792, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000025815", 
                        "id": "ENSMUSG00000025815", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2ATU0", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2ATU0", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "dehydrogenase E1 and transketolase domain-containing protein 1"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2ATU0", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2ATU0", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Dehydrogenase E1 and transketolase domain-containing protein 1"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2ATU0", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "1.2.4.2"
        }
    ]
}