{ "uniprot_canonical_ac": "A2AI05-1", "ptm_annotation": [], "sequence": { "header": "sp|A2AI05-1|NDOR1_MOUSE Isoform 1 of NADPH-dependent diflavin oxidoreductase 1 OS=Mus musculus OX=10090 GN=Ndor1 PE=2 SV=1 CANONICAL=A2AI05-1", "length": 598, "sequence": "MQVPQLLVLFGSQTGTAQDEAERLGREARRRRLGCRVQALDSYSVANLIREPLVIFVCATTGQGDPPDNMKNFWRFIFRKSLPSSSLCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPPCLGDDQHELGPDAAIDPWVGDLWEKIMVMYPVPLDIPEIPHGVPLPSKFIFQFLQEVPSIGAEELNIASSAPQTPPSELQPFLAPVITNQRVTGPQHFQDVRLIEFDITDSNISFAAGDVVFILPSNSEAHTQQFCQVLCLDPNQFFTLKPREPGVPDPPGLPQPCTVWNLVSQYLDIASVPRRSFFELLACLSQHALEREKLLELSSARGQEELWEYCSRPRRTILEVLCDFPHTAGAIPPDYLLDLIPRIRPRAFSIASSLLAHPRRLQILVAVVKYQTRLKEPRHGLCSSWLASLNPGQAGPVRVPLWVRPGSLVFPKTPDTPIIMVGAGTGVAPFRAAIQERVAHGQTGNFLFFGCRQRDQDFYWQTEWQKLEQKGWLTLVTAFSREQEQKVYVQHRLRELGPLVWELLDGQGAYFYLAGNAKYLPTDVSEALMSIFQEEGRLSTADASAYLARLQQTLRFQTETWA" }, "uniprot_id": "NDOR1_MOUSE", "enzyme_annotation": [ { "ec": "1.18.1.-", "activity": "" } ], "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/30694175", "type": [ "PubMed" ], "id": "30694175" } ], "title": "Long-term consequences of the absence of leptin signaling in early life.", "journal": "eLife", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075945.1", "id": "NP_001075945.1", "database": "RefSeq" } ], "authors": "Ramos-Lobo AM, Teixeira PD, Furigo IC, Melo HM, de M Lyra E Silva N, De Felice FG, Donato J Jr", "date": "2019" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/30815534", "type": [ "PubMed" ], "id": "30815534" } ], "title": "Deletion of Ripk3 Prevents Motor Neuron Death In Vitro but not In Vivo.", "journal": "eNeuro", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075945.1", "id": "NP_001075945.1", "database": "RefSeq" } ], "authors": "Dermentzaki G, Politi KA, Lu L, Mishra V, Perez-Torres EJ, Sosunov AA, McKhann GM 2nd, Lotti F, Shneider NA, Przedborski S", "date": "2019" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/31118412", "type": [ "PubMed" ], "id": "31118412" } ], "title": "iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications.", "journal": "Nature communications", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075945.1", "id": "NP_001075945.1", "database": "RefSeq" } ], "authors": "Fernandez-Chacon M, Casquero-Garcia V, Luo W, Francesca Lunella F, Ferreira Rocha S, Del Olmo-Cabrera S, Benedito R", "date": "2019" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/18064675", "type": [ "PubMed" ], "id": "18064675" } ], "title": "Generation of mice with a conditional allele of the p120 Ras GTPase-activating protein.", "journal": "Genesis (New York, N.Y. : 2000)", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075945.1", "id": "NP_001075945.1", "database": "RefSeq" } ], "authors": "Lapinski PE, Bauler TJ, Brown EJ, Hughes ED, Saunders TL, King PD", "date": "2007" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/17437992", "type": [ "PubMed" ], "id": "17437992" } ], "title": "The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis.", "journal": "Genes & development", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075945.1", "id": "NP_001075945.1", "database": "RefSeq" } ], "authors": "Lum JJ, Bui T, Gruber M, Gordan JD, DeBerardinis RJ, Covello KL, Simon MC, Thompson CB", "date": "2007" } ], "uniprot_ac": "A2AI05", "site_annotation": [ { "end_pos": 241, "annotation": "n_glycosylation_sequon", "start_pos": 239 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2AI05#A0A2I3BPW1-1", "isoform_ac": "A0A2I3BPW1-1", "locus": { "end_pos": 25245778, "strand": "+", "start_pos": 25246200, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000228627", "id": "ENSMUST00000228627", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000153819", "id": "ENSMUSP00000153819", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A2I3BPW1-1|NDOR1_MOUSE Computationally mapped isoform of NADPH-dependent diflavin oxidoreductase 1 OS=Mus musculus OX=10090 GN=Ndor1 PE=2 SV=2 CANONICAL=A2AI05-1", "length": 141, "sequence": "MTPRADLGRVCCPLCRQKTPMLEWEICQLQEELLRADGPQRPMRTASVTALHPGPWPWGPLEHRYQLRFLAGPVGGRSCLPFLPCPPSLGTWLWALRERGPCARRLSLLSLLVLELLGLVVIFMPLLLLGVLFMLLDRSTH" } }, { "url": "https://www.uniprot.org/uniprot/A2AI05#F6XCS1-1", "isoform_ac": "F6XCS1-1", "locus": { "end_pos": 25249472, "strand": "+", "start_pos": 25255346, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000141808", "id": "ENSMUST00000141808", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000123247", "id": "ENSMUSP00000123247", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F6XCS1-1|NDOR1_MOUSE Computationally mapped isoform of NADPH-dependent diflavin oxidoreductase 1 OS=Mus musculus OX=10090 GN=Ndor1 PE=2 SV=1 CANONICAL=A2AI05-1", "length": 225, "sequence": "XVPQLLVLFGSQTGTAQDEAERLGREARRRRLGCRVQALDSYSVANLIREPLVIFVCATTGQGDPPDNMKNFWRFIFRKSLPSSSLCQMDFAVLGLGDSSYAKPDAAIDPWVGDLWEKIMVMYPVPLDIPEIPHGVPLPSKFIFQFLQEVPSIGAEELNIASSAPQTPPSELQPFLAPVITNQRVTGPQHFQDVRLIEFDITDSNISFAAGDVVFILPSNSEAHT" } }, { "url": "https://www.uniprot.org/uniprot/A2AI05#E0CX27-1", "isoform_ac": "E0CX27-1", "locus": { "end_pos": 25254931, "strand": "+", "start_pos": 25255351, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000132128", "id": "ENSMUST00000132128", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000125018", "id": "ENSMUSP00000125018", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E0CX27-1|NDOR1_MOUSE Computationally mapped isoform of NADPH-dependent diflavin oxidoreductase 1 OS=Mus musculus OX=10090 GN=Ndor1 PE=2 SV=1 CANONICAL=A2AI05-1", "length": 71, "sequence": "MQVPQLLVLFGSQTGTAQDEAERLGREARRRRLGCRVQALDSYSVVRLGRYGGDPPPDFAPSDGGRLSESH" } }, { "url": "https://www.uniprot.org/uniprot/A2AI05#E0CXI9-1", "isoform_ac": "E0CXI9-1", "locus": { "end_pos": 25250125, "strand": "+", "start_pos": 25255351, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000147866", "id": "ENSMUST00000147866", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000125259", "id": "ENSMUSP00000125259", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E0CXI9-1|NDOR1_MOUSE Computationally mapped isoform of NADPH-dependent diflavin oxidoreductase 1 OS=Mus musculus OX=10090 GN=Ndor1 PE=2 SV=1 CANONICAL=A2AI05-1", "length": 212, "sequence": "MQVPQLLVLFGSQTGTAQDEAERLGREARRRRLGCRVQALDSYSVVRLGRYGGDPPPDFAPSDGGRLSEGGGGMRCREGTDQGCQRPYIYLCLVLEANLIREPLVIFVCATTGQGDPPDNMKNFWRFIFRKSLPSSSLCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPPCLGDDQHELGPDAAIDPWVGDLWEKIMVMYPVPL" } }, { "url": "https://www.uniprot.org/uniprot/A2AI05#E0CYR1-1", "isoform_ac": "E0CYR1-1", "locus": { "end_pos": 25254917, "strand": "+", "start_pos": 25255351, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000148589", "id": "ENSMUST00000148589", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000123958", "id": "ENSMUSP00000123958", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E0CYR1-1|NDOR1_MOUSE Computationally mapped isoform of NADPH-dependent diflavin oxidoreductase 1 OS=Mus musculus OX=10090 GN=Ndor1 PE=2 SV=1 CANONICAL=A2AI05-1", "length": 82, "sequence": "MQVPQLLVLFGSQTGTAQDEAERLGREARRRRLGCRVQALDSYSVVKVVVGCGAGRALIKAARDLTSTCVLSSRRISLGSPW" } }, { "url": "https://www.uniprot.org/uniprot/A2AI05#A2AI05-1", "isoform_ac": "A2AI05-1", "locus": { "end_pos": 25247713, "strand": "+", "start_pos": 25255351, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000114349", "id": "ENSMUST00000114349", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000109989", "id": "ENSMUSP00000109989", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2AI05-1|NDOR1_MOUSE Isoform 1 of NADPH-dependent diflavin oxidoreductase 1 OS=Mus musculus OX=10090 GN=Ndor1 PE=2 SV=1 CANONICAL=A2AI05-1", "length": 598, "sequence": "MQVPQLLVLFGSQTGTAQDEAERLGREARRRRLGCRVQALDSYSVANLIREPLVIFVCATTGQGDPPDNMKNFWRFIFRKSLPSSSLCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPPCLGDDQHELGPDAAIDPWVGDLWEKIMVMYPVPLDIPEIPHGVPLPSKFIFQFLQEVPSIGAEELNIASSAPQTPPSELQPFLAPVITNQRVTGPQHFQDVRLIEFDITDSNISFAAGDVVFILPSNSEAHTQQFCQVLCLDPNQFFTLKPREPGVPDPPGLPQPCTVWNLVSQYLDIASVPRRSFFELLACLSQHALEREKLLELSSARGQEELWEYCSRPRRTILEVLCDFPHTAGAIPPDYLLDLIPRIRPRAFSIASSLLAHPRRLQILVAVVKYQTRLKEPRHGLCSSWLASLNPGQAGPVRVPLWVRPGSLVFPKTPDTPIIMVGAGTGVAPFRAAIQERVAHGQTGNFLFFGCRQRDQDFYWQTEWQKLEQKGWLTLVTAFSREQEQKVYVQHRLRELGPLVWELLDGQGAYFYLAGNAKYLPTDVSEALMSIFQEEGRLSTADASAYLARLQQTLRFQTETWA" } }, { "url": "https://www.uniprot.org/uniprot/A2AI05#A2AI05-2", "isoform_ac": "A2AI05-2", "locus": { "end_pos": 25247713, "strand": "+", "start_pos": 25255351, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000100329", "id": "ENSMUST00000100329", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000097903", "id": "ENSMUSP00000097903", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2AI05-2|NDOR1_MOUSE Isoform 2 of NADPH-dependent diflavin oxidoreductase 1 OS=Mus musculus OX=10090 GN=Ndor1 PE=2 SV=1 CANONICAL=A2AI05-1", "length": 531, "sequence": "MQVPQLLVLFGSQTGTAQDEAERLGREARRRRLGCRVQALDSYSVANLIREPLVIFVCATTGQGDPPDNMKNFWRFIFRKSLPSSSLCQMDFAVLGLGDSSYANLPSKFIFQFLQEVPSIGAEELNIASSAPQTPPSELQPFLAPVITNQRVTGPQHFQDVRLIEFDITDSNISFAAGDVVFILPSNSEAHTQQFCQVLCLDPNQFFTLKPREPGVPDPPGLPQPCTVWNLVSQYLDIASVPRRSFFELLACLSQHALEREKLLELSSARGQEELWEYCSRPRRTILEVLCDFPHTAGAIPPDYLLDLIPRIRPRAFSIASSLLAHPRRLQILVAVVKYQTRLKEPRHGLCSSWLASLNPGQAGPVRVPLWVRPGSLVFPKTPDTPIIMVGAGTGVAPFRAAIQERVAHGQTGNFLFFGCRQRDQDFYWQTEWQKLEQKGWLTLVTAFSREQEQKVYVQHRLRELGPLVWELLDGQGAYFYLAGNAKYLPTDVSEALMSIFQEEGRLSTADASAYLARLQQTLRFQTETWA" } }, { "url": "https://www.uniprot.org/uniprot/A2AI05#A2AI05-3", "isoform_ac": "A2AI05-3", "locus": {}, "sequence": { "header": "sp|A2AI05-3|NDOR1_MOUSE Isoform 3 of NADPH-dependent diflavin oxidoreductase 1 OS=Mus musculus OX=10090 GN=Ndor1 PE=2 SV=1 CANONICAL=A2AI05-1", "length": 466, "sequence": "MRCREGTDQGCQRPYIYLCLVLEANLIREPLVIFVCATTGQGDPPDNMKNFWRFIFRKSLPSSSLCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPPCLGDDQHELGPDAAIDPWVGDLWEKIMVMYPVPLDIPEIPHGVPLPSKFIFQFLQEVPSIGAEELNIASSAPQTPPSELQPFLAPVITNQRVTGPQHFQDVRLIEFDITDSNISFAAGDVVFILPSNSEAHTQQFCQVLCLDPNQFFTLKPREPGVPDPPGLPQPCTVWNLVSQYLDIASVPRRSFFELLACLSQHALEREKLLELSSARGQEELWEYCSRPRRTILEVLCDFPHTAGAIPPDYLLDLIPRIRPRAFSIASSLLAHPRRLQILVAVVKYQTRLKEPRHGLCSSWLASLNPGQAGPVRVPLWVRPGSLVFPKTPDTPIIMVGAGTGVAPFRAAIQERVAHGQTGEYWSSKAV" } }, { "url": "https://www.uniprot.org/uniprot/A2AI05#A0A2I3BQN1-1", "isoform_ac": "A0A2I3BQN1-1", "locus": { "end_pos": 25245778, "strand": "+", "start_pos": 25254869, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000228052", "id": "ENSMUST00000228052", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000154261", "id": "ENSMUSP00000154261", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A2I3BQN1-1|NDOR1_MOUSE Computationally mapped isoform of NADPH-dependent diflavin oxidoreductase 1 OS=Mus musculus OX=10090 GN=Ndor1 PE=2 SV=1 CANONICAL=A2AI05-1", "length": 662, "sequence": "MKNFWRFIFRKSLPSSSLCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPPCLGDDQHELGPDAAIDPWVGDLWEKIMVMYPVPLDIPEIPHGVPLPSKFIFQFLQEVPSIGAEELNIASSAPQTPPSELQPFLAPVITNQRVTGPQHFQDVRLIEFDITDSNISFAAGDVVFILPSNSEAHTQQFCQVLCLDPNQFFTLKPREPGVPDPPGLPQPCTVWNLVSQYLDIASVPRRSFFELLACLSQHALEREKLLELSSARGQEELWEYCSRPRRTILEVLCDFPHTAGAIPPDYLLDLIPRIRPRAFSIASSLLAHPRRLQILVAVVKYQTRLKEPRHGLCSSWLASLNPGQAGPVRVPLWVRPGSLVFPKTPDTPIIMVGAGTGVAPFRAAIQERVAHGQTGNFLFFGCRQRDQDFYWQTEWQKLEQKGWLTLVTAFSREQSSWSLRLRILTSVLVVTWDLMTPALCLLVHPVLLWVLSSWTHCASYQQMERMISGPLWVPELQTVNRNWRPETHPLPGPWSQLWKSRKKTPMLEWEICQLQEELLRADGPQRPMRTASVTALHPGPWPWGPLEHRYQLRFLAGPVGGRSCLPFLPCPPSLGTWLWALRERGPCARRLSLLSLLVLELLGLVVIFMPLLLLGVLFMLLDRSTH" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:78797", "resource": "KEGG Pathway", "id": "mmu:78797", "name": "" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A2AI05#function", "annotation": "Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05#function", "id": "A2AI05", "database": "UniProtKB" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q9UHB4-1", "protein_name": "NADPH-dependent diflavin oxidoreductase 1", "sequence": { "length": 597, "sequence": "MPSPQLLVLFGSQTGTAQDVSERLGREARRRRLGCRVQALDSYPVVNLINEPLVIFVCATTGQGDPPDNMKNFWRFIFRKNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGSALLPVCLGDDQHELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFTLLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDILGSGISFAAGDVVLIQPSNSAAHVQRFCQVLGLDPDQLFMLQPREPDVSSPTRLPQPCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEPRRGLCSSWLASLDPGQGPVRVPLWVRPGSLAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQGQTGNFLFFGCRWRDQDFYWEAEWQELEKRDCLTLIPAFSREQEQKVYVQHRLRELGSLVWELLDRQGAYFYLAGNAKSMPADVSEALMSIFQEEGGLCSPDAAAYLARLQQTRRFQTETWA" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/7144", "id": "7144", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "tax_id": 9606 }, { "uniprot_canonical_ac": "D4ABT4-1", "protein_name": "NADPH-dependent diflavin oxidoreductase 1", "sequence": { "length": 598, "sequence": "MQVPQLLVLFGSQTGTAQDEAERLGREARRRRLGCRVQALDSYSVANLIREPLVIFVCATTGQGDPPDNMKNFWRFIFRKSLPSTSLCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQLGGNALVPPCLGDDQHELGPDAAIDPWVGDLWEKIMTMYPVPLDIPEIPHGVPLPSKFIFQFLQEVPSIGAEELNLASSAPQTPPSELQPFLAPVVTNQRVTGPQHFQDVRLMEFDITESNISFAAGDVVLILPSNSEAHTKQFCQLLCLDPNQFFTLKPREPGVPYPPGLPQHCTVWHLVSQYLDIASVPRRSFFELLACLSPHALEREKLLEFSSARGQEELWEYCNRPRRTILEVLCDFPHTAGAIPPDYLLDLIPRIRPRAFSIASSLLAHPRRLQILVAVVKYQTRLKEPRRGLCSSWLASLTPGQAGPVRVPLWVRPGSLVFPKTPGTPIIMVGPGTGVAPFRAAIQERVAHGQMGNVLFFGCRQRDQDFYWQTEWQELEQRGCLTLVTAFSREQAQKVYVQHRLRELGPLVWELLDGQGAYFYLAGNAKYMPTDVSEALTAIFQEEGRLSTTDAAAYLARLQQTLRFQTETWA" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/7144", "id": "7144", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/A2AI05/", "id": "A2AI05", "database": "OMA" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "tax_id": 10116 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075945.1", "ac": "NP_001075945.1", "name": "NADPH-dependent diflavin oxidoreductase 1 isoform 1", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003958", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "NADPH-hemoprotein reductase activity", "id": "GO:0003958" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "flavin adenine dinucleotide binding", "id": "GO:0050660" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "oxidoreductase activity", "id": "GO:0016491" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010181", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "FMN binding", "id": "GO:0010181" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050661", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "NADP binding", "id": "GO:0050661" } ], "total": 5, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "nucleus", "id": "GO:0005634" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "cytosol", "id": "GO:0005829" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "perinuclear region of cytoplasm", "id": "GO:0048471" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045111", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "intermediate filament cytoskeleton", "id": "GO:0045111" } ], "total": 5, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016226", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "iron-sulfur cluster assembly", "id": "GO:0016226" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036245", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "cellular response to menadione", "id": "GO:0036245" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055114", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "oxidation-reduction process", "id": "GO:0055114" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008219", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "id": "A2AI05", "database": "UniProtKB" } ], "name": "cell death", "id": "GO:0008219" } ], "total": 4, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AI05", "type": "synonym", "resource": "RefSeq", "name": "Ndor1" }, { "url": "https://www.uniprot.org/uniprot/A2AI05", "type": "recommended", "resource": "UniProtKB", "name": "Ndor1" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AI05", "type": "synonym", "resource": "RefSeq", "name": "4930447P04Rik; Ndor; NR1; Tg(UBC-cre/ERT2)1Ejb; Ubc-cre" } ], "crossref": [ { "url": "http://www.informatics.jax.org/marker/MGI:1926047", "id": "1926047", "database": "MGI" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR017938", "id": "IPR017938", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF00667", "id": "PF00667", "database": "Pfam" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR017927", "id": "IPR017927", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR008254", "id": "IPR008254", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001433", "id": "IPR001433", "database": "InterPro" }, { "url": "http://pfam.xfam.org/family/PF00258", "id": "PF00258", "database": "Pfam" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/78797", "id": "78797", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR023173", "id": "IPR023173", "database": "InterPro" }, { "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2AI05", "id": "PR_A2AI05", "database": "PRO" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR039261", "id": "IPR039261", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001094", "id": "IPR001094", "database": "InterPro" }, { "url": "https://omabrowser.org/oma/group/FEMMPLI/", "id": "FEMMPLI", "database": "OMA" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001709", "id": "IPR001709", "database": "InterPro" }, { "url": "http://www.orthodb.org/?query=318396at2759", "id": "318396at2759", "database": "OrthoDB" }, { "url": "http://pfam.xfam.org/family/PF00175", "id": "PF00175", "database": "Pfam" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR028879", "id": "IPR028879", "database": "InterPro" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001075945.1", "id": "NP_001075945.1", "database": "RefSeq" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR029039", "id": "IPR029039", "database": "InterPro" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000006471", "id": "ENSMUSG00000006471", "database": "Bgee" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR003097", "id": "IPR003097", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:78797", "id": "mmu:78797", "database": "KEGG Pathway" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 67183.0, "chemical_mass": 67183.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "name": "Ndor1", "locus": { "end_pos": 25244863, "strand": "-", "start_pos": 25255386, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000115074", "id": "ENSMUSG00000115074", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A2AI05", "type": "synonym", "resource": "UniProtKB", "name": "1.18.1.-" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AI05", "type": "synonym", "resource": "RefSeq", "name": "NADPH-dependent FMN and FAD-containing oxidoreductase; Tg(UBC-cre)1Ejb; Tg(UBC-cre/ESR1)1Ejb" }, { "url": "https://www.uniprot.org/uniprot/A2AI05", "type": "recommended", "resource": "UniProtKB", "name": "NADPH-dependent diflavin oxidoreductase 1" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AI05", "type": "synonym", "resource": "RefSeq", "name": "NADPH-dependent diflavin oxidoreductase 1 isoform 1" }, { "url": "https://www.uniprot.org/uniprot/A2AI05", "type": "synonym", "resource": "UniProtKB", "name": "NADPH-dependent FMN and FAD-containing oxidoreductase" } ] }