{ "uniprot_canonical_ac": "A2AB59-1", "ptm_annotation": [], "sequence": { "header": "sp|A2AB59-1|RHG27_MOUSE Isoform 1 of Rho GTPase-activating protein 27 OS=Mus musculus OX=10090 GN=Arhgap27 PE=1 SV=1 CANONICAL=A2AB59-1", "length": 869, "sequence": "MAADVEGDVYVLVEHPFEYTGKDGRRIAIQPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPAPAPQPSVPQQRPAVPEPLAYDYRFVSTPVGADGSSAEPRGRASSLCGPARQRTGGQRNSLAPGGPACLYVRPAAPVRPAQSLDDLARGGTAPPAGLLGSAGHFKASSVAGSWVCPRPLAPSDSENVYEAIPDLRCPPRAESPKQVDDPPEPVYANVERQPRATSPRSAAAPPRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFETPEGTTSPATSRASVGSGESLETEWGQYWDEESRRVFFYNPLTGETAWEDETEELEEDHQEQLEMQPSLSPRSPGQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASPLVAPPGWSCQITPDKQMLYTNQFTQEQWVRLEDQHGKPYFYNPEDSSVQWELPQVPIPAPRSVRKSSQDSDTPAQASPPEEKIKTLDKAGVLHRTKTVDKGKRLRKKHWSTSWTVLEGGVLTFFKDSKTSAAGGLRQPSKLSTPEYTVELKGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGISELSADLLQGEEGEPSSADFGSSERLGSWREEDVRQNAASPSLSPGGLESDLSRVRHKLRKFLQRRPTLQSLRDKGYIKDQVFGCALAQLCERERSPVPRFVQQCIRTVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRSRCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH" }, "uniprot_id": "RHG27_MOUSE", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/17242355", "type": [ "PubMed" ], "id": "17242355" } ], "title": "Large-scale phosphorylation analysis of mouse liver.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "authors": "Beausoleil S.A., Gerber S.A., Gygi S.P., Villen J.", "date": "2007" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/26073538", "type": [ "PubMed" ], "id": "26073538" } ], "title": "Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.", "journal": "American journal of reproductive immunology (New York, N.Y. : 1989)", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192165.1", "id": "NP_001192165.1", "database": "RefSeq" } ], "authors": "Pan J, Mor G, Ju W, Zhong J, Luo X, Aldo PB, Zhong M, Yu Y, Jenkins EC, Brown WT, Zhong N", "date": "2015" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/18034455", "type": [ "PubMed" ], "id": "18034455" } ], "title": "Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain.", "journal": "J. Proteome Res.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "authors": "Ballif B.A., Gygi S.P., Sunyaev S.R., Carey G.R.", "date": "2008" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/15147912", "type": [ "PubMed" ], "id": "15147912" } ], "title": "Identification and characterization of a novel Rho GTPase activating protein implicated in receptor-mediated endocytosis.", "journal": "FEBS Lett.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "authors": "Nukiwa T., Takeshima H., Sakakibara T., Nemoto Y.", "date": "2004" } ], "uniprot_ac": "A2AB59", "site_annotation": [], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A2AB59#A2AKN5-1", "isoform_ac": "A2AKN5-1", "locus": { "end_pos": 103360172, "strand": "+", "start_pos": 103360900, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000092557", "id": "ENSMUST00000092557", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000102637", "id": "ENSMUSP00000102637", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A2AKN5-1|RHG27_MOUSE Computationally mapped isoform of Rho GTPase-activating protein 27 OS=Mus musculus OX=10090 GN=Arhgap27 PE=1 SV=1 CANONICAL=A2AB59-1", "length": 243, "sequence": "MAADVEGDVYVLVEHPFEYTGKDGRRIAIQPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPAPAPQPSVPQQRPAVPEPLAYDYRFVSTPVGADGSSAEPRGRASSLCGPARQRTGGQRNSLAPGGPACLYVRPAAPVRPAQSLDDLARGGTAPPAGLLGSAGHFKASSVAGSWVCPRPLAPSDSENVYEAIPDLRCPPRAESPKQVGRCERGGRREVTVQQSLDAFFFFN" } }, { "url": "https://www.uniprot.org/uniprot/A2AB59#A2AB59-2", "isoform_ac": "A2AB59-2", "locus": { "end_pos": 103332866, "strand": "+", "start_pos": 103344566, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000041385", "id": "ENSMUST00000041385", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000039427", "id": "ENSMUSP00000039427", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2AB59-2|RHG27_MOUSE Isoform 2 of Rho GTPase-activating protein 27 OS=Mus musculus OX=10090 GN=Arhgap27 PE=1 SV=1 CANONICAL=A2AB59-1", "length": 670, "sequence": "MVDMISKLVRRQSRALRAQVDDPPEPVYANVERQPRATSPRSAAAPPRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFETPEGTTSPATSRASVGSGESLETEWGQYWDEESRRVFFYNPLTGETAWEDETEELEEDHQEQLEMQPSLSPRSPGQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASPLVAPPGWSCQITPDKQMLYTNQFTQEQWVRLEDQHGKPYFYNPEDSSVQWELPQVPIPAPRSVRKSSQDSDTPAQASPPEEKIKTLDKAGVLHRTKTVDKGKRLRKKHWSTSWTVLEGGVLTFFKDSKTSAAGGLRQPSKLSTPEYTVELKGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGISELSADLLQGEEGEPSSADFGSSERLGSWREEDVRQNAASPSLSPGGLESDLSRVRHKLRKFLQRRPTLQSLRDKGYIKDQVFGCALAQLCERERSPVPRFVQQCIRTVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRSRCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH" } }, { "url": "https://www.uniprot.org/uniprot/A2AB59#A2AB70-1", "isoform_ac": "A2AB70-1", "locus": { "end_pos": 103340135, "strand": "+", "start_pos": 103356365, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000107023", "id": "ENSMUST00000107023", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000102638", "id": "ENSMUSP00000102638", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A2AB70-1|RHG27_MOUSE Computationally mapped isoform of Rho GTPase-activating protein 27 OS=Mus musculus OX=10090 GN=Arhgap27 PE=1 SV=1 CANONICAL=A2AB59-1", "length": 123, "sequence": "MQTAPEALLLSSDRAWTETPPEPSFLPPQPAGTVDDPPEPVYANVERQPRATSPRSAAAPPRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFETPEGTTSPATSRASVGSGESLETEWGQY" } }, { "url": "https://www.uniprot.org/uniprot/A2AB59#E9Q6V8-1", "isoform_ac": "E9Q6V8-1", "locus": { "end_pos": 103339229, "strand": "+", "start_pos": 103340026, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000136491", "id": "ENSMUST00000136491", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000128051", "id": "ENSMUSP00000128051", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E9Q6V8-1|RHG27_MOUSE Computationally mapped isoform of Rho GTPase-activating protein 27 OS=Mus musculus OX=10090 GN=Arhgap27 PE=1 SV=1 CANONICAL=A2AB59-1", "length": 91, "sequence": "MQPSLSPRSPGQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASPLVAPPGWSCQITPDKQMLYTNQFTQEQWVRLEDQHGKPYFYNP" } }, { "url": "https://www.uniprot.org/uniprot/A2AB59#A2AB59-1", "isoform_ac": "A2AB59-1", "locus": { "end_pos": 103332866, "strand": "+", "start_pos": 103360900, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000107024", "id": "ENSMUST00000107024", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000102639", "id": "ENSMUSP00000102639", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A2AB59-1|RHG27_MOUSE Isoform 1 of Rho GTPase-activating protein 27 OS=Mus musculus OX=10090 GN=Arhgap27 PE=1 SV=1 CANONICAL=A2AB59-1", "length": 869, "sequence": "MAADVEGDVYVLVEHPFEYTGKDGRRIAIQPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPAPAPQPSVPQQRPAVPEPLAYDYRFVSTPVGADGSSAEPRGRASSLCGPARQRTGGQRNSLAPGGPACLYVRPAAPVRPAQSLDDLARGGTAPPAGLLGSAGHFKASSVAGSWVCPRPLAPSDSENVYEAIPDLRCPPRAESPKQVDDPPEPVYANVERQPRATSPRSAAAPPRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFETPEGTTSPATSRASVGSGESLETEWGQYWDEESRRVFFYNPLTGETAWEDETEELEEDHQEQLEMQPSLSPRSPGQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASPLVAPPGWSCQITPDKQMLYTNQFTQEQWVRLEDQHGKPYFYNPEDSSVQWELPQVPIPAPRSVRKSSQDSDTPAQASPPEEKIKTLDKAGVLHRTKTVDKGKRLRKKHWSTSWTVLEGGVLTFFKDSKTSAAGGLRQPSKLSTPEYTVELKGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGISELSADLLQGEEGEPSSADFGSSERLGSWREEDVRQNAASPSLSPGGLESDLSRVRHKLRKFLQRRPTLQSLRDKGYIKDQVFGCALAQLCERERSPVPRFVQQCIRTVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRSRCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:544817", "resource": "KEGG Pathway", "id": "mmu:544817", "name": "" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-194840", "resource": "Reactome", "id": "R-MMU-194840", "name": "Rho GTPase cycle" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A2AB59#function", "annotation": "Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59#function", "id": "A2AB59", "database": "UniProtKB" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q6ZUM4-1", "protein_name": "Rho GTPase-activating protein 27", "sequence": { "length": 889, "sequence": "MAADVVGDVYVLVEHPFEYTGKDGRRVAIRPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGNPAAAAPPGPHPSPAAPEPLAYDYRFVSAAATAGPDGAPEESGGRASSLCGPAQRGAATQRSSLAPGLPACLYLRPAAPVRPAQSLNDLACAAVSPPAGLLGSSGSFKACSVAGSWVCPRPLARSDSENVYEVIQDLHVPPPEESAEQVDDPPEPVYANIERQPRATSPGAAAAPLPSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEAAEGAASPATSPASVDSHVSLETEWGQYWDEESRRVFFYNPLTGETAWEDEAENEPEEELEMQPGLSPGSPGDPRPPTPETDYPESLTSYPEEDYSPVGSFGEPGPTSPLTTPPGWSCHVSQDKQMLYTNHFTQEQWVRLEDPHGKPYFYNPEDSSVRWELPQVPVPAPRSIHKSSQDGDTPAQASPPEEKVPAELDEVGSWEEVSPATAAVRTKTLDKAGVLHRTKTADKGKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAGGLRQPSKFSTPEYTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAQGIQELSAELPPEESESSRVDFGSSERLGSWQEKEEDARPNAAAPALGPVGLESDLSKVRHKLRKFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPMTMVFQNQVVELILQQCADIFPPH" }, "evidence": [ { "url": "https://omabrowser.org/oma/group/A2AB59/", "id": "A2AB59", "database": "OMA" }, { "url": "http://www.informatics.jax.org/homology/45715", "id": "45715", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "tax_id": 9606 }, { "uniprot_canonical_ac": "Q6TLK4-1", "protein_name": "Rho GTPase-activating protein 27", "sequence": { "length": 869, "sequence": "MAADVEGDVYVLVEHPFEYTGKDGRLIAIQPNERCRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPVPAPQPSVLQQRPTVPEPLAYDYRFVSTPVGADGSSAEPRGRASSLCGPARQRTSGQRNSLAPGGPACLYLRPAAPVRPAQSLDDLARGGTAPPAGLLGSAGHFKASSVAGSWVCPRPLARSDSENVYEAIPDLRCPPRAKSPKQVDEPPEPVYANVERQPQVTSPRSAAAPPRLSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEAPEGATSPTTSRASVGSGESLETEWGQYWDEESGRVFFYNPLTGETVWEDETEELEDDPEEQLEMQPSLSPRSPGQQRPPTPETDYPELLTSYPEEDYSPVGSFSDLGPTSPLVAPPGWSCQITPEKQMLYTNQFTQEQWVRLEDQEGKPYFYNPEDSSVQWELPQVPVPAPRSGRKSSQDSDTPAQASPPEEKIKTLDKAGVLHRTKTVDKGKRLRKKHWNASWTVLEGGVLTFFKDSKTSAASGLRQPSKLSTPEYTVELRGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGIEELSADLPQREEGEPSSADFGSSERLGSWKEEDVRPNAASPSLNPGSQESDLSRVRHKLRKFLQRRPTLQSLREKGYIKDQVFGCALAQLCERERSPVPRFVQQCIRTVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRSRCVRDLVRTLPAPNHDTLRLLIQHLCRVIEHGEQNRMSVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/45715", "id": "45715", "database": "MGI" } ], "common_name": "Rat", "organism": "Rattus norvegicus", "tax_id": 10116 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192165.1", "ac": "NP_001192165.1", "name": "rho GTPase-activating protein 27 isoform 1", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "name": "GTPase activator activity", "id": "GO:0005096" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "name": "SH3 domain binding", "id": "GO:0017124" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "name": "nucleus", "id": "GO:0005634" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "name": "nucleoplasm", "id": "GO:0005654" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "name": "endosome", "id": "GO:0005768" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "name": "cytosol", "id": "GO:0005829" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "name": "membrane", "id": "GO:0016020" } ], "total": 6, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043087", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "name": "regulation of GTPase activity", "id": "GO:0043087" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "name": "signal transduction", "id": "GO:0007165" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043547", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "name": "positive regulation of GTPase activity", "id": "GO:0043547" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006898", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "id": "A2AB59", "database": "UniProtKB" } ], "name": "receptor-mediated endocytosis", "id": "GO:0006898" } ], "total": 4, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AB59", "type": "synonym", "resource": "RefSeq", "name": "2310069I04Rik; 5730442P18Rik; Gm21552; Sh3d20" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AB59", "type": "synonym", "resource": "RefSeq", "name": "Arhgap27" }, { "url": "https://www.uniprot.org/uniprot/A2AB59", "type": "recommended", "resource": "UniProtKB", "name": "Arhgap27" }, { "url": "https://www.uniprot.org/uniprot/A2AB59", "type": "synonym", "resource": "UniProtKB", "name": "Camgap1" } ], "crossref": [ { "url": "http://www.informatics.jax.org/marker/MGI:1916903", "id": "1916903", "database": "MGI" }, { "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2AB59", "id": "PR_A2AB59", "database": "PRO" }, { "url": "http://pfam.xfam.org/family/PF00397", "id": "PF00397", "database": "Pfam" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "id": "IPR000198", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "id": "IPR001849", "database": "InterPro" }, { "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "id": "cd00201", "database": "CDD" }, { "url": "https://omabrowser.org/oma/group/DDRGQTY/", "id": "DDRGQTY", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=1300981at2759", "id": "1300981at2759", "database": "OrthoDB" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/544817", "id": "544817", "database": "GeneID" }, { "url": "http://pfam.xfam.org/family/PF00620", "id": "PF00620", "database": "Pfam" }, { "url": "http://pfam.xfam.org/family/PF00169", "id": "PF00169", "database": "Pfam" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-194840", "id": "R-MMU-194840", "database": "Reactome" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "id": "IPR008936", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "id": "IPR001452", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "id": "IPR011993", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "id": "IPR011047", "database": "InterPro" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000034255", "id": "ENSMUSG00000034255", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001192165.1", "id": "NP_001192165.1", "database": "RefSeq" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "id": 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"start_pos": 103363692, "chromosome": "11", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000034255", "id": "ENSMUSG00000034255", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A2AB59", "type": "synonym", "resource": "UniProtKB", "name": "Rho-type GTPase-activating protein 27" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AB59", "type": "synonym", "resource": "RefSeq", "name": "rho GTPase-activating protein 27 isoform 1" }, { "url": "https://www.uniprot.org/uniprot/A2AB59", "type": "synonym", "resource": "UniProtKB", "name": "CIN85-associated multi-domain-containing Rho GTPase-activating protein 1" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A2AB59", "type": "synonym", "resource": "RefSeq", "name": "rho-type GTPase-activating protein 27; CIN85-associated multi-domain-containing Rho GTPase-activating protein 1; SH3 domain containing 20" }, { "url": "https://www.uniprot.org/uniprot/A2AB59", "type": "recommended", "resource": "UniProtKB", "name": "Rho GTPase-activating protein 27" } ] }