{
    "uniprot_canonical_ac": "A1L3P4-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "tr|A1L3P4-1|A1L3P4_MOUSE Isoform 1 of Sodium/hydrogen exchanger  OS=Mus musculus OX=10090 GN=Slc9a6 PE=1 SV=1 CANONICAL=A1L3P4-1", 
        "length": 702, 
        "sequence": "MAGARRGWRLAPVRRGVCGPRARPLMRPLWLLFAVSFFGWTGALDGSGGTTRAMDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYTLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFIAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEHLGVPDNERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTESATASAPRRFMGNSSEDALDRELTFGDHELVIRGTRLVLPMDDSEPALNSLDDTRHSPA"
    }, 
    "uniprot_id": "A1L3P4_MOUSE", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                    "id": "A1L3P4", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/26965387", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "26965387"
                }
            ], 
            "title": "Emerging roles of Na(+)/H(+) exchangers in epilepsy and developmental brain disorders.", 
            "journal": "Progress in neurobiology", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
                    "id": "NP_766368.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Zhao H, Carney KE, Falgoust L, Pan JW, Sun D, Zhang Z", 
            "date": "2016"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/21171650", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "21171650"
                }
            ], 
            "title": "Organellar Na+/H+ exchangers: novel players in organelle pH regulation and their emerging functions.", 
            "journal": "Biochemistry", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
                    "id": "NP_766368.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Ohgaki R, van IJzendoorn SC, Matsushita M, Hoekstra D, Kanazawa H", 
            "date": "2011"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/26515654", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "26515654"
                }
            ], 
            "title": "X-linked Christianson syndrome: heterozygous female Slc9a6 knockout mice develop mosaic neuropathological changes and related behavioral abnormalities.", 
            "journal": "Disease models & mechanisms", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
                    "id": "NP_766368.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Sikora J, Leddy J, Gulinello M, Walkley SU", 
            "date": "2016"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/19144319", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "19144319"
                }
            ], 
            "title": "The phagosomal proteome in interferon-gamma-activated macrophages.", 
            "journal": "Immunity", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                    "id": "A1L3P4", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Thibault P., Trost M., Desjardins M., Courcelles M., English L., Lemieux S.", 
            "date": "2009"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/17005858", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "17005858"
                }
            ], 
            "title": "Vestibular hair bundles control pH with (Na+, K+)/H+ exchangers NHE6 and NHE9.", 
            "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
                    "id": "NP_766368.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Hill JK, Brett CL, Chyou A, Kallay LM, Sakaguchi M, Rao R, Gillespie PG", 
            "date": "2006"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/29946028", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "29946028"
                }
            ], 
            "title": "Amyloid clearance defect in ApoE4 astrocytes is reversed by epigenetic correction of endosomal pH.", 
            "journal": "Proceedings of the National Academy of Sciences of the United States of America", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
                    "id": "NP_766368.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Prasad H, Rao R", 
            "date": "2018"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/29349289", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "29349289"
                }
            ], 
            "title": "Mixed Neurodevelopmental and Neurodegenerative Pathology in Nhe6-Null Mouse Model of Christianson Syndrome.", 
            "journal": "eNeuro", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
                    "id": "NP_766368.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Xu M, Ouyang Q, Gong J, Pescosolido MF, Pruett BS, Mishra S, Schmidt M, Jones RN, Gamsiz Uzun ED, Lizarraga SB, Morrow EM", 
            "date": "2017"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/15522866", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "15522866"
                }
            ], 
            "title": "Four Na+/H+ exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation.", 
            "journal": "The Journal of biological chemistry", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
                    "id": "NP_766368.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Nakamura N, Tanaka S, Teko Y, Mitsui K, Kanazawa H", 
            "date": "2005"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/29351414", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "29351414"
                }
            ], 
            "title": "The murine choroid plexus epithelium expresses the 2Cl(-)/H(+) exchanger ClC-7 and Na(+)/H(+) exchanger NHE6 in the luminal membrane domain.", 
            "journal": "American journal of physiology. Cell physiology", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
                    "id": "NP_766368.2", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Damkier HH, Christensen HL, Christensen IB, Wu Q, Fenton RA, Praetorius J", 
            "date": "2018"
        }
    ], 
    "uniprot_ac": "A1L3P4", 
    "site_annotation": [
        {
            "end_pos": 404, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 402
        }, 
        {
            "end_pos": 658, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 656
        }, 
        {
            "end_pos": 148, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 146
        }, 
        {
            "end_pos": 131, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 129
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L3P4#A1L3P4-1", 
            "isoform_ac": "A1L3P4-1", 
            "locus": {
                "end_pos": 56609860, 
                "strand": "-", 
                "start_pos": 56661445, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000077741", 
                        "id": "ENSMUST00000077741", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000076922", 
                        "id": "ENSMUSP00000076922", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A1L3P4-1|A1L3P4_MOUSE Isoform 1 of Sodium/hydrogen exchanger  OS=Mus musculus OX=10090 GN=Slc9a6 PE=1 SV=1 CANONICAL=A1L3P4-1", 
                "length": 702, 
                "sequence": "MAGARRGWRLAPVRRGVCGPRARPLMRPLWLLFAVSFFGWTGALDGSGGTTRAMDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYTLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFIAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEHLGVPDNERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTESATASAPRRFMGNSSEDALDRELTFGDHELVIRGTRLVLPMDDSEPALNSLDDTRHSPA"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L3P4#A0A140LJ55-1", 
            "isoform_ac": "A0A140LJ55-1", 
            "locus": {
                "end_pos": 56645848, 
                "strand": "-", 
                "start_pos": 56661380, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000207892", 
                        "id": "ENSMUST00000207892", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000147081", 
                        "id": "ENSMUSP00000147081", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A140LJ55-1|A1L3P4_MOUSE Computationally mapped isoform of Sodium/hydrogen exchanger  OS=Mus musculus OX=10090 GN=Slc9a6 PE=1 SV=2 CANONICAL=A1L3P4-1", 
                "length": 206, 
                "sequence": "XYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRYYARLWGYRDELTHGLYPQEAHSLFGETDRVGVDSDQEHLGVPDNERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTESATASAPRRFMGNSSEDALDRELTFGDHELVIRGTRL"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L3P4#D3Z0Q9-1", 
            "isoform_ac": "D3Z0Q9-1", 
            "locus": {
                "end_pos": 56610019, 
                "strand": "-", 
                "start_pos": 56634839, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000144068", 
                        "id": "ENSMUST00000144068", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000115364", 
                        "id": "ENSMUSP00000115364", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|D3Z0Q9-1|A1L3P4_MOUSE Computationally mapped isoform of Sodium/hydrogen exchanger  OS=Mus musculus OX=10090 GN=Slc9a6 PE=1 SV=2 CANONICAL=A1L3P4-1", 
                "length": 313, 
                "sequence": "MDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYTLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLF"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L3P4#B0QZV3-1", 
            "isoform_ac": "B0QZV3-1", 
            "locus": {
                "end_pos": 56609860, 
                "strand": "-", 
                "start_pos": 56661445, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000114784", 
                        "id": "ENSMUST00000114784", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000110432", 
                        "id": "ENSMUSP00000110432", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|B0QZV3-1|A1L3P4_MOUSE Computationally mapped isoform of Sodium/hydrogen exchanger  OS=Mus musculus OX=10090 GN=Slc9a6 PE=1 SV=1 CANONICAL=A1L3P4-1", 
                "length": 670, 
                "sequence": "MAGARRGWRLAPVRRGVCGPRARPLMRPLWLLFAVSFFGWTGALDGSGGTTRAMDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFIAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEHLGVPDNERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTESATASAPRRFMGNSSEDALDRELTFGDHELVIRGTRLVLPMDDSEPALNSLDDTRHSPA"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-425986", 
            "resource": "Reactome", 
            "id": "R-MMU-425986", 
            "name": "Sodium/Proton exchangers"
        }
    ], 
    "function": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
            "annotation": "NHE6 is expressed in the inner ear", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
                    "id": "NP_766368.2", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
            "annotation": "NHE6 and ClC-7 are both expressed in the choroid plexus epithelial cells, and are potentially involved in pH regulation of the CSF.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
                    "id": "NP_766368.2", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
            "annotation": "Analysis of the heterozygous Slc9a6 KO female mice model of X-linked Christianson syndrome", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
                    "id": "NP_766368.2", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
            "annotation": "This review describes Nhe6 knockout mice, which partially mimic phenotypical features of patients suffering from mental disorders including motor hyperactivity and a lowered threshold for pharmacologically induced seizures. Review article", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
                    "id": "NP_766368.2", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q92581-1", 
            "protein_name": "Sodium/hydrogen exchanger 6", 
            "sequence": {
                "length": 669, 
                "sequence": "MARRGWRRAPLRRGVGSSPRARRLMRPLWLLLAVGVFDWAGASDGGGGEARAMDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPATSSAPRRFMGNSSEDALDRELAFGDHELVIRGTRLVLPMDDSEPPLNLLDNTRHGPA"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/55971", 
                    "id": "55971", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
        "ac": "NP_766368.2", 
        "name": "sodium/hydrogen exchanger 6 isoform 1", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015385", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "sodium:proton antiporter activity", 
                        "id": "GO:0015385"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015386", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "potassium:proton antiporter activity", 
                        "id": "GO:0015386"
                    }
                ], 
                "total": 2, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", 
                        "pmid": "14651853", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "mitochondrion", 
                        "id": "GO:0005739"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", 
                        "pmid": "24035762", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "endosome", 
                        "id": "GO:0005768"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", 
                        "pmid": "24035762", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "early endosome", 
                        "id": "GO:0005769"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", 
                        "pmid": "23303939", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "plasma membrane", 
                        "id": "GO:0005886"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", 
                        "pmid": "23303939", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "dendrite", 
                        "id": "GO:0030425"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", 
                        "pmid": "23303939", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "axon terminus", 
                        "id": "GO:0043679"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", 
                        "pmid": "24035762", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "synapse", 
                        "id": "GO:0045202"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", 
                        "pmid": "23303939", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "recycling endosome", 
                        "id": "GO:0055037"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055037", 
                        "pmid": "24035762", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "recycling endosome", 
                        "id": "GO:0055037"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", 
                        "pmid": "23303939", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasmic vesicle", 
                        "id": "GO:0031410"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005770", 
                        "pmid": "24035762", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "late endosome", 
                        "id": "GO:0005770"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044308", 
                        "pmid": "23303939", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "axonal spine", 
                        "id": "GO:0044308"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043231", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "intracellular membrane-bounded organelle", 
                        "id": "GO:0043231"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "endoplasmic reticulum membrane", 
                        "id": "GO:0005789"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "early endosome membrane", 
                        "id": "GO:0031901"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055038", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "recycling endosome membrane", 
                        "id": "GO:0055038"
                    }
                ], 
                "total": 17, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050808", 
                        "pmid": "24035762", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "synapse organization", 
                        "id": "GO:0050808"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048812", 
                        "pmid": "24035762", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "neuron projection morphogenesis", 
                        "id": "GO:0048812"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060996", 
                        "pmid": "24035762", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "dendritic spine development", 
                        "id": "GO:0060996"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048675", 
                        "pmid": "24035762", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "axon extension", 
                        "id": "GO:0048675"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097484", 
                        "pmid": "24035762", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "dendrite extension", 
                        "id": "GO:0097484"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "regulation of intracellular pH", 
                        "id": "GO:0051453"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "potassium ion transmembrane transport", 
                        "id": "GO:0071805"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031547", 
                        "pmid": "24035762", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "brain-derived neurotrophic factor receptor signaling pathway", 
                        "id": "GO:0031547"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902600", 
                        "pmid": "24035762", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "proton transmembrane transport", 
                        "id": "GO:1902600"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051386", 
                        "pmid": "24035762", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "regulation of neurotrophin TRK receptor signaling pathway", 
                        "id": "GO:0051386"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098719", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A1L3P4", 
                                "id": "A1L3P4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "sodium ion import across plasma membrane", 
                        "id": "GO:0098719"
                    }
                ], 
                "total": 11, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1L3P4", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Slc9a6"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L3P4", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Slc9a6"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1L3P4", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "3732426M05; 6430520C02Rik; mKIAA0267; NHE6"
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR004709", 
            "id": "IPR004709", 
            "database": "InterPro"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000060681", 
            "id": "ENSMUSG00000060681", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/236794", 
            "id": "236794", 
            "database": "GeneID"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10110", 
            "id": "PTHR10110", 
            "database": "PANTHER"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018422", 
            "id": "IPR018422", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006153", 
            "id": "IPR006153", 
            "database": "InterPro"
        }, 
        {
            "url": "https://acgg.asia/gpdb2/GPDB0001581", 
            "id": "GPDB0001581", 
            "database": "GlycoProtDB"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-425986", 
            "id": "R-MMU-425986", 
            "database": "Reactome"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002090", 
            "id": "IPR002090", 
            "database": "InterPro"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:2443511", 
            "id": "2443511", 
            "database": "MGI"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_766368.2", 
            "id": "NP_766368.2", 
            "database": "RefSeq"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00999", 
            "id": "PF00999", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.orthodb.org/?query=559433at2759", 
            "id": "559433at2759", 
            "database": "OrthoDB"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 77953.0, 
        "chemical_mass": 77953.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A1L3P4", 
            "name": "Slc9a6", 
            "locus": {
                "end_pos": 56664230, 
                "strand": "+", 
                "start_pos": 56609757, 
                "chromosome": "X", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000060681", 
                        "id": "ENSMUSG00000060681", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1L3P4", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "sodium/hydrogen exchanger 6 isoform 1"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A1L3P4", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "solute carrier family 9 (sodium/hydrogen exchanger), isoform 6"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A1L3P4", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Sodium/hydrogen exchanger"
        }
    ]
}