{
    "uniprot_canonical_ac": "A6H666-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A6H666-1|COX8C_MOUSE Isoform 1 of Cytochrome c oxidase subunit 8C, mitochondrial  OS=Mus musculus OX=10090 GN=Cox8c PE=3 SV=1 CANONICAL=A6H666-1", 
        "length": 72, 
        "sequence": "MSRLLLLCSSLLRHRAVLFSKPGHPGRLSHSESPQKKILSPTESAVGIVVFFTTFYIPAAYVLSSLKYFKGE"
    }, 
    "uniprot_id": "COX8C_MOUSE", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A6H666", 
                    "id": "A6H666", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/12762575", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "12762575"
                }
            ], 
            "title": "Genetic aspects of susceptibility to air pollution.", 
            "journal": "The European respiratory journal. Supplement", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034138.1", 
                    "id": "NP_001034138.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Kleeberger SR", 
            "date": "2003"
        }
    ], 
    "uniprot_ac": "A6H666", 
    "site_annotation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A6H666#A6H666-1", 
            "isoform_ac": "A6H666-1", 
            "locus": {
                "end_pos": 102899366, 
                "start_pos": 102900334, 
                "chromosome": "12", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000053611", 
                        "id": "ENSMUST00000053611", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000056155", 
                        "id": "ENSMUSP00000056155", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A6H666-1|COX8C_MOUSE Isoform 1 of Cytochrome c oxidase subunit 8C, mitochondrial  OS=Mus musculus OX=10090 GN=Cox8c PE=3 SV=1 CANONICAL=A6H666-1", 
                "length": 72, 
                "sequence": "MSRLLLLCSSLLRHRAVLFSKPGHPGRLSHSESPQKKILSPTESAVGIVVFFTTFYIPAAYVLSSLKYFKGE"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:75483", 
            "resource": "KEGG Pathway", 
            "id": "mmu:75483", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A6H666#function", 
            "annotation": "This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A6H666#function", 
                    "id": "A6H666", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q7TNN2-1", 
            "protein_name": "Cytochrome c oxidase subunit 8C, mitochondrial", 
            "sequence": {
                "length": 72, 
                "sequence": "MSRLLQFCSSLLRHRVVLFSKPGHSGRLSHSESPQNQVLTPTESVVGIVVFFATFFIPAAYVMSNLKFFKGE"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/83496", 
                    "id": "83496", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A6H666/", 
                    "id": "A6H666", 
                    "database": "OMA"
                }
            ], 
            "common_name": "rats", 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034138.1", 
        "ac": "NP_001034138.1", 
        "name": "cytochrome c oxidase subunit 8C, mitochondrial", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004129", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A6H666", 
                                "id": "A6H666", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytochrome-c oxidase activity", 
                        "id": "GO:0004129"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", 
                        "pmid": "18614015", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A6H666", 
                                "id": "A6H666", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "mitochondrion", 
                        "id": "GO:0005739"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045277", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A6H666", 
                                "id": "A6H666", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "respiratory chain complex IV", 
                        "id": "GO:0045277"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A6H666", 
                                "id": "A6H666", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "mitochondrial inner membrane", 
                        "id": "GO:0005743"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A6H666", 
                                "id": "A6H666", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }
                ], 
                "total": 4, 
                "name": "Cellular Component"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A6H666", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "1700007F21Rik; COX8-3; COXVIII-3"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A6H666", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Cox8c"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6H666", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Cox8c"
        }
    ], 
    "crossref": [
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16717", 
            "id": "PTHR16717", 
            "database": "PANTHER"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/75483", 
            "id": "75483", 
            "database": "GeneID"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000043319", 
            "id": "ENSMUSG00000043319", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036548", 
            "id": "IPR036548", 
            "database": "InterPro"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF02285", 
            "id": "PF02285", 
            "database": "Pfam"
        }, 
        {
            "url": "http://www.orthodb.org/?query=1624891at2759", 
            "id": "1624891at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:1922733", 
            "id": "1922733", 
            "database": "MGI"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:75483", 
            "id": "mmu:75483", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003205", 
            "id": "IPR003205", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001034138.1", 
            "id": "NP_001034138.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/CRHYRRV/", 
            "id": "CRHYRRV", 
            "database": "OMA"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A6H666", 
            "id": "PR_A6H666", 
            "database": "PRO"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 8009.0, 
        "chemical_mass": 8009.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A6H666", 
            "name": "Cox8c", 
            "locus": {
                "end_pos": 102900526, 
                "start_pos": 102899316, 
                "chromosome": "12", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000043319", 
                        "id": "ENSMUSG00000043319", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A6H666", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "cytochrome c oxidase subunit 8C, mitochondrial"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6H666", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Cytochrome c oxidase polypeptide 8 isoform 3"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6H666", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Cytochrome c oxidase polypeptide VIII isoform 3"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6H666", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Cytochrome c oxidase subunit 8C, mitochondrial"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6H666", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Cytochrome c oxidase subunit 8-3"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A6H666", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "COX VIII-3"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A6H666", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "COX VIII-3; cytochrome c oxidase subunit 8-3; cytochrome c oxidase polypeptide 8; cytochrome c oxidase subunit VIIIc; cytochrome c oxidase polypeptide VIII"
        }
    ]
}