{
    "uniprot_canonical_ac": "A0JPQ8-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A0JPQ8-1|ALKMO_RAT Isoform 1 of Alkylglycerol monooxygenase  OS=Rattus norvegicus OX=10116 GN=Agmo PE=2 SV=1 CANONICAL=A0JPQ8-1", 
        "length": 447, 
        "sequence": "MRNPGAQDNVSVSQGMRAMFYMMKPSETAFQTVEEVPDYVKKATPFFIFLILLELVVSWILKGKPSGRLDDILTSMSAGVVSRLPNLFFRSLEVTSYIYIWENYRVCELPWDSPWTWYLTFLGVDFGYYWFHRMAHEINIIWAAHQAHHSSEDYNLSTALRQSVLQQYSSWVFYCPLALFVPPSVFAVHIQFNLLYQFWIHTEVIRTLGPLELVLNTPSHHRVHHGRNRYCIDKNYAGTLIIWDRIFGTFEAENEQVIYGLTHPIGTFEPFKVQFHHLLYIWTTFWATPGFCHKFSVLFKGPGWGPGKPRLGLSEEIPEVTGQEVPFTSSASQFLKIYAVLQFAVMLVFYEETFANTAVLSQVTILLRICFIILTLTSIGFLLDQRPKAAIVETLRCLLFLTLYRFGHLKPLIESLSFAFEIFFSVCIAFWGVRSITHLASGSWKKP"
    }, 
    "uniprot_id": "ALKMO_RAT", 
    "enzyme_annotation": [
        {
            "ec": "1.14.16.5", 
            "activity": "1-alkyl-sn-glycerol + tetrahydrobiopterin + O(2) = 1-O-alkyl-sn-glycerol + dihydrobiopterin + H(2)O."
        }, 
        {
            "ec": "1.14.16.5", 
            "activity": ""
        }
    ], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "rats", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
                    "id": "A0JPQ8", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Rattus norvegicus", 
            "taxid": 10116
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/20643956", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "20643956"
                }
            ], 
            "title": "Identification of the gene encoding alkylglycerol monooxygenase defines a third class of tetrahydrobiopterin-dependent enzymes.", 
            "journal": "Proceedings of the National Academy of Sciences of the United States of America", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129371.1", 
                    "id": "NP_001129371.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Watschinger K, Keller MA, Golderer G, Hermann M, Maglione M, Sarg B, Lindner HH, Hermetter A, Werner-Felmayer G, Konrat R, Hulo N, Werner ER", 
            "date": "2010"
        }
    ], 
    "uniprot_ac": "A0JPQ8", 
    "site_annotation": [
        {
            "end_pos": 11, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 9
        }, 
        {
            "end_pos": 157, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 155
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A0JPQ8#A0JPQ8-1", 
            "isoform_ac": "A0JPQ8-1", 
            "locus": {
                "end_pos": 56846994, 
                "start_pos": 57193289, 
                "chromosome": "6", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOT00000032108", 
                        "id": "ENSRNOT00000032108", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOP00000029816", 
                        "id": "ENSRNOP00000029816", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A0JPQ8-1|ALKMO_RAT Isoform 1 of Alkylglycerol monooxygenase  OS=Rattus norvegicus OX=10116 GN=Agmo PE=2 SV=1 CANONICAL=A0JPQ8-1", 
                "length": 447, 
                "sequence": "MRNPGAQDNVSVSQGMRAMFYMMKPSETAFQTVEEVPDYVKKATPFFIFLILLELVVSWILKGKPSGRLDDILTSMSAGVVSRLPNLFFRSLEVTSYIYIWENYRVCELPWDSPWTWYLTFLGVDFGYYWFHRMAHEINIIWAAHQAHHSSEDYNLSTALRQSVLQQYSSWVFYCPLALFVPPSVFAVHIQFNLLYQFWIHTEVIRTLGPLELVLNTPSHHRVHHGRNRYCIDKNYAGTLIIWDRIFGTFEAENEQVIYGLTHPIGTFEPFKVQFHHLLYIWTTFWATPGFCHKFSVLFKGPGWGPGKPRLGLSEEIPEVTGQEVPFTSSASQFLKIYAVLQFAVMLVFYEETFANTAVLSQVTILLRICFIILTLTSIGFLLDQRPKAAIVETLRCLLFLTLYRFGHLKPLIESLSFAFEIFFSVCIAFWGVRSITHLASGSWKKP"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-75109", 
            "resource": "Reactome", 
            "id": "R-RNO-75109", 
            "name": "Triglyceride biosynthesis"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:362732", 
            "resource": "KEGG Pathway", 
            "id": "rno:362732", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A0JPQ8#function", 
            "annotation": "Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes (By similarity).", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A0JPQ8#function", 
                    "id": "A0JPQ8", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q6ZNB7-1", 
            "protein_name": "Alkylglycerol monooxygenase", 
            "sequence": {
                "length": 445, 
                "sequence": "MKNPEAQQDVSVSQGFRMLFYTMKPSETSFQTLEEVPDYVKKATPFFISLMLLELVVSWILKGKPPGRLDDALTSISAGVLSRLPSLFFRSIELTSYIYIWENYRLFNLPWDSPWTWYSAFLGVDFGYYWFHRMAHEVNIMWAGHQTHHSSEDYNLSTALRQSVLQIYTSWIFYSPLALFIPPSVYAVHLQFNLLYQFWIHTEVINNLGPLELILNTPSHHRVHHGRNRYCIDKNYAGVLIIWDKIFGTFEAENEKVVYGLTHPINTFEPIKVQFHHLFSIWTTFWATPGFFNKFSVIFKGPGWGPGKPRLGLSEEIPEVTGKEVPFSSSSSQLLKIYTVVQFALMLAFYEETFADTAALSQVTLLLRVCFIILTLTSIGFLLDQRPKAAIMETLRCLMFLMLYRFGHLKPLVPSLSSAFEIVFSICIAFWGVRSMKQLTSHPWK"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A0JPQ8/", 
                    "id": "A0JPQ8", 
                    "database": "OMA"
                }, 
                {
                    "url": "http://www.informatics.jax.org/homology/45620", 
                    "id": "45620", 
                    "database": "MGI"
                }
            ], 
            "common_name": "man", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }, 
        {
            "uniprot_canonical_ac": "Q8BS35-1", 
            "protein_name": "Alkylglycerol monooxygenase", 
            "sequence": {
                "length": 447, 
                "sequence": "MRSPGAQDNVSVSQGMRAMFYMMEPSETAFQTVEEVPDYVKKATPFFIFLILLELVISWILKGKPSGRLDDALTSISAGVVSRLPSLFFRSLEVTSYIYIWENYRLLELPWDSTWTWYFTFLGVDFGYYWFHRMAHEINIFWAAHQAHHSSEDYNLSTALRQSVLQQYSSWVFYCPLALFIPPSVFAVHIQFNLLYQFWIHTEIIRTLGPLEVILNTPSHHRVHHGRNRYCIDKNYAGTLIIWDRIFGTFEAENEQVIYGLTHPIGTFEPFNVQFHHLLYIWTTFWTTPGFCHKFSVLFKGPGWGPGKPRLGLSEEIPEVTGQEVPFSSSASQLLKIYTVLQFAVMLAFYEETFANTAVLSQVTLLLRIFFFILTLTSIGFLLDQRSKAATMETFRCLLFLTLHRFGHLKPLIPSLSFAFEIFFSVCIAFWGVRSITQLTSGSWKKP"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/45620", 
                    "id": "45620", 
                    "database": "MGI"
                }
            ], 
            "common_name": "mouse", 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129371.1", 
        "ac": "NP_001129371.1", 
        "name": "alkylglycerol monooxygenase", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
                                "id": "A0JPQ8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "iron ion binding", 
                        "id": "GO:0005506"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050479", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
                                "id": "A0JPQ8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "glyceryl-ether monooxygenase activity", 
                        "id": "GO:0050479"
                    }
                ], 
                "total": 2, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
                                "id": "A0JPQ8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "endoplasmic reticulum", 
                        "id": "GO:0005783"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
                                "id": "A0JPQ8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
                                "id": "A0JPQ8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "endoplasmic reticulum membrane", 
                        "id": "GO:0005789"
                    }
                ], 
                "total": 3, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008610", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
                                "id": "A0JPQ8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "lipid biosynthetic process", 
                        "id": "GO:0008610"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006643", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
                                "id": "A0JPQ8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "membrane lipid metabolic process", 
                        "id": "GO:0006643"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046485", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
                                "id": "A0JPQ8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ether lipid metabolic process", 
                        "id": "GO:0046485"
                    }
                ], 
                "total": 3, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Tmem195"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0JPQ8", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "RGD1312038; Tmem195"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0JPQ8", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Agmo"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Agmo"
        }
    ], 
    "crossref": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/362732", 
            "id": "362732", 
            "database": "GeneID"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/FMPTGWR/", 
            "id": "FMPTGWR", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=1446475at2759", 
            "id": "1446475at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000023116", 
            "id": "ENSRNOG00000023116", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-75109", 
            "id": "R-RNO-75109", 
            "database": "Reactome"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A0JPQ8", 
            "id": "PR_A0JPQ8", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:362732", 
            "id": "rno:362732", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001129371.1", 
            "id": "NP_001129371.1", 
            "database": "RefSeq"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF04116", 
            "id": "PF04116", 
            "database": "Pfam"
        }, 
        {
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1312038", 
            "id": "1312038", 
            "database": "RGD"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006694", 
            "id": "IPR006694", 
            "database": "InterPro"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 51698.0, 
        "chemical_mass": 51698.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
            "name": "Agmo", 
            "locus": {
                "end_pos": 57193961, 
                "start_pos": 56846789, 
                "chromosome": "6", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSRNOG00000023116", 
                        "id": "ENSRNOG00000023116", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Transmembrane protein 195"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Alkylglycerol monooxygenase"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A0JPQ8", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "1.14.16.5"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0JPQ8", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "alkylglycerol monooxygenase"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A0JPQ8", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "transmembrane protein 195"
        }
    ]
}