{ "uniprot_canonical_ac": "A0A087WSF2-1", "ptm_annotation": [], "sequence": { "header": "tr|A0A087WSF2-1|A0A087WSF2_MOUSE Isoform 1 of Sperm motility kinase 3C OS=Mus musculus OX=10090 GN=Smok3c PE=4 SV=1 CANONICAL=A0A087WSF2-1", "length": 504, "sequence": "MGPGSQQKSEKLRCKPPFSNMDGFHAQYVMLETIGHGGCATVKLAQHRLTGTHVAVKTIQKRGYWCILIMSEVDLLMMADHPNVISLLQVIETKKKVYLIMELCEGKSLYQHIRKAGYLQEHEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLSTKVKPGQKLNLFCGTYPFSAPEVLLSTPYDGPKIDVWTLGVVLYFMVTGKIPFDACSIKRLVKRILAGKYSIPSRLSAELRDLLSLLMTANPKLRPTVAEVMVHPWVTEGSGVFPDPCEEQTPLKPDPAIVKAMGHIGFQAQDIEDSLRQRKFNQTMASYCLLKKQILKECDRPTRARPVNPSVTPFPSLVDTATTCLGLRRRENEPTCPWSSANRQVSVCGKSTSKKRDRRVSWPSVLGRPRHTAPTMDHTRTRTRSVPCICSMFCTVQPNSSEESTQGHTRASAADKPVRSRGWPRGIKGWTRMIGNAMRKLCCCIPSKETSHLGQNRVSPKK" }, "uniprot_id": "A0A087WSF2_MOUSE", "enzyme_annotation": [], "glycation": [], "keywords": [], "species": [ { "common_name": "mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WSF2", "id": "A0A087WSF2", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "publication": [], "uniprot_ac": "A0A087WSF2", "site_annotation": [ { "end_pos": 325, "annotation": "n_glycosylation_sequon", "start_pos": 323 }, { "end_pos": 443, "annotation": "n_glycosylation_sequon", "start_pos": 441 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A0A087WSF2#A0A087WSF2-1", "isoform_ac": "A0A087WSF2-1", "locus": { "end_pos": 138066254, "start_pos": 138066537, "chromosome": "5", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000110967", "id": "ENSMUST00000110967", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000141020", "id": "ENSMUSP00000141020", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|A0A087WSF2-1|A0A087WSF2_MOUSE Isoform 1 of Sperm motility kinase 3C OS=Mus musculus OX=10090 GN=Smok3c PE=4 SV=1 CANONICAL=A0A087WSF2-1", "length": 504, "sequence": "MGPGSQQKSEKLRCKPPFSNMDGFHAQYVMLETIGHGGCATVKLAQHRLTGTHVAVKTIQKRGYWCILIMSEVDLLMMADHPNVISLLQVIETKKKVYLIMELCEGKSLYQHIRKAGYLQEHEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLSTKVKPGQKLNLFCGTYPFSAPEVLLSTPYDGPKIDVWTLGVVLYFMVTGKIPFDACSIKRLVKRILAGKYSIPSRLSAELRDLLSLLMTANPKLRPTVAEVMVHPWVTEGSGVFPDPCEEQTPLKPDPAIVKAMGHIGFQAQDIEDSLRQRKFNQTMASYCLLKKQILKECDRPTRARPVNPSVTPFPSLVDTATTCLGLRRRENEPTCPWSSANRQVSVCGKSTSKKRDRRVSWPSVLGRPRHTAPTMDHTRTRTRSVPCICSMFCTVQPNSSEESTQGHTRASAADKPVRSRGWPRGIKGWTRMIGNAMRKLCCCIPSKETSHLGQNRVSPKK" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:622486", "resource": "KEGG Pathway", "id": "mmu:622486", "name": "" } ], "function": [], "orthologs": [ { "uniprot_canonical_ac": "M0RD88-1", "protein_name": "Sperm motility kinase 2A", "sequence": { "length": 501, "sequence": "MSFGSKRASERLRSQGSSCTESFCSQYLVLNTIGHGFHAAVKLAVHRLTGTPVAVKMILKRQQWCQQVTSEVEIMMRINHPNIVSLIQVIDTEKITYLIMELAKGNQLYSHIKEAGHLQEDEARGIFRQLLSAVGYCHEEGIIHRDLKPDNLLVDTKGRIKIIDFGSATQVRPGQKLRTPYGTYAFSAPELLLGKFYEGPKVDVWALGVILYYMTVGKVPFEAASIPLLRRQIVLGTCVVPPGLSEELQDLLSLLLKVNSQQRPTIPDLLTHPWLKIDSEGFPQLCKELIPLRPDPAILRAMQDIGFEAQEVKDSLDQKKFNQSMACYYLLEKQALQECDNPTRPHPCMTPFPTLDYPATSVRGLRSRGSEPRWLGSSSDSQGSDLGQTPSHGLVKRASWPGGLLCRPRQIAPTVELTHRISISDPCFSSVHSRGKKTINTESTEDKSSDSAEVKPVASRPWPKRFRGWLKNIRNGLMNLCCCIPSRKKPPLGHNRVVPQK" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/128738", "id": "128738", "database": "MGI" } ], "common_name": "rats", "organism": "Rattus norvegicus", "tax_id": 10116 }, { "uniprot_canonical_ac": "C0HKC8-1", "protein_name": "Sperm motility kinase 3A", "sequence": { "length": 504, "sequence": "MGPGSQQKSEKLRSKSPLADMDGLHAQYVMLETIGHGGCATVKLAQHRLTGTHVAVKTIRKREYWCNRVISEVELLMMADHPNIISLLQVIETKKKVYLIMELCKGKSLYQHIRKAGYLQEHEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLGTKVKPGQKLNLFCGTYPFSAPEVLLSTPYDGPKIDVWTLGVVLYFMVTGKIPFDACSIKKLVKRILAGKYSIPSRLSAELQDLLSLLMTANPKLRPTVAEVMVHPWVTEGSGVFPDPCEEQTPLKPDPAIVKAMGHIGFQAQDIEDSLRQRKFNQTMASYCLLKKQILKECDRPTRARPVNPSVTPFPSLVDTATTRLGLRRRENEPTCPWSSANRQVSVCGKSTSKKRDRRVSWPSVLGRPRHTAPTMDHTRTRTRSVPCICSMFCTVQPNSSEESTQGHTRASAADKPVHSRGWPRGIKGWTRMIGNAMRKLCCCIPSKETSHLGQNRVSPKK" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/128738", "id": "128738", "database": "MGI" } ], "common_name": "mouse", "organism": "Mus musculus", "tax_id": 10090 }, { "uniprot_canonical_ac": "M0RDM0-1", "protein_name": "Similar to putative protein kinase", "sequence": { "length": 501, "sequence": "MSFRSKRESERLRSQGSSCTESFCSQYLVLNTIGHGFHAAVKLAVHRLTGTPVAVKMLLKRQQWCQQVTSEVEIMMRINHPNIVSLIQVIDTEKITYLIMELAKGNQLYSRIKEAGHLQEDEARGIFRQLLSAVGYCHKEGIIHRDLKPDNILVDTKGRIKIVDFGSATQVRPGQKLRTHYGTYAFSAPELFLGKFYEGPKVDVWALGVILYYMTVGKLPFEAVRLPLLRRQVVLGTYAEPLGLSEELQDLLSLLMKVNSQQRPTIPDLLTHPWLKIDSEGFPQPCKELIPLRPDPAILRAMQDIGFEAQEVKDSLDQKKFNQSMACYYFLEKQALQECDIPTRPHPCMTPFPTLDYPATSVRGLRRRGSEPRWLGSSSDSQGSDLGQTASHGLVKRASWPGGLLCRPHQITPTVELTHRISISDPCFYSVHSKGKKTINTKSTEDKSSASAEVKPVASRPWPKRFRGWVKNIRNGLMNLCCCIPSRKKPPLGHNRVVPQK" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/128738", "id": "128738", "database": "MGI" } ], "common_name": "rats", "organism": "Rattus norvegicus", "tax_id": 10116 }, { "uniprot_canonical_ac": "D3ZBS8-1", "protein_name": "Similar to MAP/microtubule affinity-regulating kinase 4 (MAP/microtubule affinity-regulating kinase-like 1)", "sequence": { "length": 502, "sequence": "MSSGSEQESERLPSEGSSYTESFHSQYMILNTIGHGGYATVKLALHRLTGTPVAVKILIKKEHWCHPVTSEVDIMMSIHHPNIISLFQVIETKKKIYLIMELAEGKQLYHRIREAGQLQEDEARGIFRQLLSATGYCHARGIVHRDLKPDNIMIDTRGRIKIIDFGLATHVRPGQKLRYHCGTYAFAAPEMLLGKLYEGPKVDVWTLGVVLYCMTVGRLPFDDSNIPQLRSQVVSGKYAVPPGMSGELKDMLSLLLKVNPQHRPTIPDLLTHPWLKTGSEGFPQPSEEWIPLRPDPAVLRAMEQIGFKAQDVKDSLYQNKYNQTVACYHLLERQALQGCDNSTRPGPMNPWMAPFPSLDNPATFPQELRRRGSEPRWLGSSSNSQGSTYDQKPSYGLVKRASWPGGRLCRPLLTTPAVDLTNRISRSVPCFSSVHSRGEKNIKSTEDKSSASAEVNPVPSRAWPKRFRGWAKNIGNGLMQLCCCFPSRKKPHLGHNRVVPQK" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/128738", "id": "128738", "database": "MGI" } ], "common_name": "rats", "organism": "Rattus norvegicus", "tax_id": 10116 }, { "uniprot_canonical_ac": "Q9QYZ3-1", "protein_name": "Sperm motility kinase 2B", "sequence": { "length": 484, "sequence": "MENFHAQYVMLETIGHGGCSKVMLARHRLTGSHVAVKMIRKSECWCNPVMSEVELLMMADHPNIISLLQVIETKKKVYLIMELCEGKSLYQHIRNAGYLQEDEARALFKQLLSAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLGTQVKPGQKLNLFCGTYPFSAPEVLLSRPYDGPKIDVWTLGVVLYFMVTGKVPFDAASIQKLVRQILAGKYFVPSRLSVELRDLISLLMTANPKLRPTVAEVMVHPWVTEGSGVFPDPCEEQMPLKPNPAIVKAMGYIGFQAQDIEDSLRQRKFNETMASYCLLKKQILKECDRPIRAQPMNPSVTPFPSLVDTSTFHLGLRRRETEPTSLRLSANRQMSVCGRSTSKKRDRRFSWPSVSGRPLHTTHTMDHTHTRTRSVPCIYSMFCTIQPNSSDDSTEGHTSASAEDKPVRSRGWPRGIKGWTRKIGNVMRKLCCCIPSKETSHVGHSRVSPKK" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/128738", "id": "128738", "database": "MGI" } ], "common_name": "mouse", "organism": "Mus musculus", "tax_id": 10090 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297632.1", "ac": "NP_001297632.1", "name": "sperm motility kinase 3C", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WSF2", "id": "A0A087WSF2", "database": "UniProtKB" } ], "name": "protein serine/threonine kinase activity", "id": "GO:0004674" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WSF2", "id": "A0A087WSF2", "database": "UniProtKB" } ], "name": "ATP binding", "id": "GO:0005524" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WSF2", "id": "A0A087WSF2", "database": "UniProtKB" } ], "name": "nucleus", "id": "GO:0005634" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WSF2", "id": "A0A087WSF2", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" } ], "total": 2, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WSF2", "id": "A0A087WSF2", "database": "UniProtKB" } ], "name": "protein phosphorylation", "id": "GO:0006468" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "pmid": "21873635", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A0A087WSF2", "id": "A0A087WSF2", "database": "UniProtKB" } ], "name": "intracellular signal transduction", "id": "GO:0035556" } ], "total": 2, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.uniprot.org/uniprot/A0A087WSF2", "type": "recommended", "resource": "UniProtKB", "name": "Smok3c" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A087WSF2", "type": "synonym", "resource": "RefSeq", "name": "EG622486" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A087WSF2", "type": "synonym", "resource": "RefSeq", "name": "Smok3c" } ], "crossref": [ { "url": "http://www.orthodb.org/?query=1127668at2759", "id": "1127668at2759", "database": "OrthoDB" }, { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000075598", "id": "ENSMUSG00000075598", "database": "Bgee" }, { "url": "http://www.informatics.jax.org/marker/MGI:3647925", "id": "3647925", "database": "MGI" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "id": "IPR011009", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:622486", "id": "mmu:622486", "database": "KEGG Pathway" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/622486", "id": "622486", "database": "GeneID" }, { "url": "http://pfam.xfam.org/family/PF00069", "id": "PF00069", "database": "Pfam" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "id": "IPR008271", "database": "InterPro" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297632.1", "id": "NP_001297632.1", "database": "RefSeq" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "id": "IPR000719", "database": "InterPro" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 56509.0, "chemical_mass": 56509.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A0A087WSF2", "name": "Smok3c", "locus": { "end_pos": 138066537, "start_pos": 138053194, "chromosome": "5", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000075598", "id": "ENSMUSG00000075598", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A0A087WSF2", "type": "synonym", "resource": "RefSeq", "name": "sperm motility kinase 3C" }, { "url": "https://www.uniprot.org/uniprot/A0A087WSF2", "type": "synonym", "resource": "UniProtKB", "name": "Sperm motility kinase 3C" } ] }