{ "uniprot_canonical_ac": "A4Q9F4-1", "ptm_annotation": [], "sequence": { "header": "sp|A4Q9F4-1|TTL11_MOUSE Isoform 1 of Tubulin polyglutamylase TTLL11 OS=Mus musculus OX=10090 GN=Ttll11 PE=1 SV=1 CANONICAL=A4Q9F4-1", "length": 727, "sequence": "MRRSSPEKKPEAEWEADAAAAAAATAAATESLPAETEKQQGVDAGAAGDPERLELEEQPKDVGRIPTPTRRHAPEEGEARVVRRLPPALPLAQPRPAARALSQLVKARGRSRSRVYRRSAGSMRPVTVDSSKARTSLDALKISLRQLRWKEFPFGRRLPCDIYWHGVSFRDSDILSGQVNKFPGMTEMVRKVTLSRALRIMQNLFPEEYNFYPRSWILPEEFQLFVSQVQTVKEGDPSWKPTFIVKPDSGCQGDGIYLIKDPCDGRLTGTLHNRPAVVQEYIRKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPNPQNLHHVFMHLTNYSLNIHSGKFVHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISLVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPMLLEVNANPSMRIEHEYELSPGVFENIPSLVDEEVKVAVIRDTLRLMDPLKKKKEIHFPDIYMDRKHRIPPVSDRMSSWKHKGSSLSIVRSQQMEKSFTSKEDLNCDPTGGDSEPNPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGPTGFRTFIRNCKLSSSSLSMAAVDILYIDITRRWNSVTVDQRDSGMCLQAFVEAFFFLAQRKFKLQPLHEQVASLIDLCEYHLSVLDEKRLLCHRGRPLQRNPPQMNRPEHSATGSSAPRVIGASKLSQS" }, "uniprot_id": "TTL11_MOUSE", "enzyme_annotation": [ { "ec": "6.-.-.-", "activity": "" } ], "glycation": [], "keywords": [], "species": [ { "common_name": "Mouse", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "id": "A4Q9F4", "database": "UniProtKB" } ], "name": "Mus musculus", "taxid": 10090 } ], "publication": [ { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/17499049", "type": [ "PubMed" ], "id": "17499049" } ], "title": "A targeted multienzyme mechanism for selective microtubule polyglutamylation.", "journal": "Mol. Cell", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "id": "A4Q9F4", "database": "UniProtKB" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084050.1", "id": "NP_084050.1", "database": "RefSeq" } ], "authors": "Janke C., Lacroix B., Rogowski K., van Dijk J., Miro J., Edde B.", "date": "2007" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/20530212", "type": [ "PubMed" ], "id": "20530212" } ], "title": "Tubulin polyglutamylation stimulates spastin-mediated microtubule severing.", "journal": "J. Cell Biol.", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "id": "A4Q9F4", "database": "UniProtKB" } ], "authors": "Gerlich D.W., Janke C., Guizetti J., Aldrian-Herrada G., Gold N.D., Lacroix B., Rogowski K., van Dijk J.", "date": "2010" }, { "reference": [ { "url": "https://www.ncbi.nlm.nih.gov/pubmed/29593216", "type": [ "PubMed" ], "id": "29593216" } ], "title": "Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.", "journal": "Nature communications", "evidence": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084050.1", "id": "NP_084050.1", "database": "RefSeq" } ], "authors": "Ye B, Liu B, Hao L, Zhu X, Yang L, Wang S, Xia P, Du Y, Meng S, Huang G, Qin X, Wang Y, Yan X, Li C, Hao J, Zhu P, He L, Tian Y, Fan Z", "date": "2018" } ], "uniprot_ac": "A4Q9F4", "site_annotation": [ { "end_pos": 343, "annotation": "n_glycosylation_sequon", "start_pos": 341 } ], "isoforms": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4#A4Q9F4-1", "isoform_ac": "A4Q9F4-1", "locus": { "end_pos": 35752236, "strand": "+", "start_pos": 35979624, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000028248", "id": "ENSMUST00000028248", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000028248", "id": "ENSMUSP00000028248", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A4Q9F4-1|TTL11_MOUSE Isoform 1 of Tubulin polyglutamylase TTLL11 OS=Mus musculus OX=10090 GN=Ttll11 PE=1 SV=1 CANONICAL=A4Q9F4-1", "length": 727, "sequence": "MRRSSPEKKPEAEWEADAAAAAAATAAATESLPAETEKQQGVDAGAAGDPERLELEEQPKDVGRIPTPTRRHAPEEGEARVVRRLPPALPLAQPRPAARALSQLVKARGRSRSRVYRRSAGSMRPVTVDSSKARTSLDALKISLRQLRWKEFPFGRRLPCDIYWHGVSFRDSDILSGQVNKFPGMTEMVRKVTLSRALRIMQNLFPEEYNFYPRSWILPEEFQLFVSQVQTVKEGDPSWKPTFIVKPDSGCQGDGIYLIKDPCDGRLTGTLHNRPAVVQEYIRKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPNPQNLHHVFMHLTNYSLNIHSGKFVHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISLVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPMLLEVNANPSMRIEHEYELSPGVFENIPSLVDEEVKVAVIRDTLRLMDPLKKKKEIHFPDIYMDRKHRIPPVSDRMSSWKHKGSSLSIVRSQQMEKSFTSKEDLNCDPTGGDSEPNPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGPTGFRTFIRNCKLSSSSLSMAAVDILYIDITRRWNSVTVDQRDSGMCLQAFVEAFFFLAQRKFKLQPLHEQVASLIDLCEYHLSVLDEKRLLCHRGRPLQRNPPQMNRPEHSATGSSAPRVIGASKLSQS" } }, { "url": "https://www.uniprot.org/uniprot/A4Q9F4#A4Q9F4-2", "isoform_ac": "A4Q9F4-2", "locus": { "end_pos": 35752236, "strand": "+", "start_pos": 35979624, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000112976", "id": "ENSMUST00000112976", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000108600", "id": "ENSMUSP00000108600", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "sp|A4Q9F4-2|TTL11_MOUSE Isoform 2 of Tubulin polyglutamylase TTLL11 OS=Mus musculus OX=10090 GN=Ttll11 PE=1 SV=1 CANONICAL=A4Q9F4-1", "length": 694, "sequence": "MRRSSPEKKPEAEWEADAAAAAAATAAATESLPAETEKQQGVDAGAAGDPERLELEEQPKDVGRIPTPTRRHAPEEGEARVVRRLPPALPLAQPRPAARALSQLVKARGRSRSRVYRRSAGSMRPVTVDSSKARTSLDALKISLRQLRWKEFPFGRRLPCDIYWHGVSFRDSDILSGQVNKFPGMTEMVRKVTLSRALRIMQNLFPEEYNFYPRSWILPEEFQLFVSQVQTVKEGDPSWKPTFIVKPDSGCQGDGIYLIKDPCDGRLTGTLHNRPAVVQEYIRKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPNPQNLHHVFMHLTNYSLNIHSGKFVHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISLVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPMLLEVNANPSMRIEHEYELSPGVFENIPSLVDEEVKVAVIRDTLRLMDPLKKKKEIQSQQMEKSFTSKEDLNCDPTGGDSEPNPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGPTGFRTFIRNCKLSSSSLSMAAVDILYIDITRRWNSVTVDQRDSGMCLQAFVEAFFFLAQRKFKLQPLHEQVASLIDLCEYHLSVLDEKRLLCHRGRPLQRNPPQMNRPEHSATGSSAPRVIGASKLSQS" } }, { "url": "https://www.uniprot.org/uniprot/A4Q9F4#A4Q9F4-3", "isoform_ac": "A4Q9F4-3", "locus": {}, "sequence": { "header": "sp|A4Q9F4-3|TTL11_MOUSE Isoform 3 of Tubulin polyglutamylase TTLL11 OS=Mus musculus OX=10090 GN=Ttll11 PE=1 SV=1 CANONICAL=A4Q9F4-1", "length": 622, "sequence": "MRRSSPEKKPEAEWEADAAAAAAATAAATESLPAETEKQQGVDAGAAGDPERLELEEQPKDVGRIPTPTRRHAPEEGEARVVRRLPPALPLAQPRPAARALSQLVKARGRSRSRVYRRSAGSMRPVTVDSSKARTSLDALKISLRQLRWKEFPFGRRLPCDIYWHGVSFRDSDILSGQVNKFPGMTEMVRKVTLSRALRIMQNLFPEEYIRKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPNPQNLHHVFMHLTNYSLNIHSGKFVHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISLVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPMLLEVNANPSMRIEHEYELSPGVFENIPSLVDEEVKVAVIRDTLRLMDPLKKKKEIQSQQMEKSFTSKEDLNCDPTGGDSEPNPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGPTGFRTFIRNCKLSSSSLSMAAVDILYIDITRRWNSVTVDQRDSGMCLQAFVEAFFFLAQRKFKLQPLHEQVASLIDLCEYHLSVLDEKRLLCHRGRPLQRNPPQMNRPEHSATGSSAPRVIGASKLSQS" } }, { "url": "https://www.uniprot.org/uniprot/A4Q9F4#E0CXL9-1", "isoform_ac": "E0CXL9-1", "locus": { "end_pos": 35902666, "strand": "+", "start_pos": 35940805, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000162172", "id": "ENSMUST00000162172", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000125199", "id": "ENSMUSP00000125199", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E0CXL9-1|TTL11_MOUSE Computationally mapped isoform of Tubulin polyglutamylase TTLL11 OS=Mus musculus OX=10090 GN=Ttll11 PE=1 SV=1 CANONICAL=A4Q9F4-1", "length": 204, "sequence": "MTEMVRKVTLSRALRIMQNLFPEEYNFYPRSWILPEEFQLFVSQVQTVKEGDPSWKPTFIVKPDSGCQGDGIYLIKDPCDGRLTGTLHNRPAVVQEYIRKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPNPQNLHHVFMHLTNYSLNIHSGKFVHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIIS" } }, { "url": "https://www.uniprot.org/uniprot/A4Q9F4#E0CY35-1", "isoform_ac": "E0CY35-1", "locus": { "end_pos": 35902648, "strand": "+", "start_pos": 35940805, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000140201", "id": "ENSMUST00000140201", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000124510", "id": "ENSMUSP00000124510", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E0CY35-1|TTL11_MOUSE Computationally mapped isoform of Tubulin polyglutamylase TTLL11 OS=Mus musculus OX=10090 GN=Ttll11 PE=1 SV=1 CANONICAL=A4Q9F4-1", "length": 210, "sequence": "MTEMVRKVTLSRALRIMQNLFPEEYNFYPRSWILPEEFQLFVSQVQTVKEGDPSWKPTFIVKPDSGCQGDGIYLIKDPCDGRLTGTLHNRPAVVQEYIRKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPNPQNLHHVFMHLTNYSLNIHSGKFVHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISLVIKTV" } }, { "url": "https://www.uniprot.org/uniprot/A4Q9F4#E0CZ80-1", "isoform_ac": "E0CZ80-1", "locus": { "end_pos": 35903126, "strand": "+", "start_pos": 35979624, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000161970", "id": "ENSMUST00000161970", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000125627", "id": "ENSMUSP00000125627", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|E0CZ80-1|TTL11_MOUSE Computationally mapped isoform of Tubulin polyglutamylase TTLL11 OS=Mus musculus OX=10090 GN=Ttll11 PE=1 SV=1 CANONICAL=A4Q9F4-1", "length": 190, "sequence": "MRRSSPEKKPEAEWEADAAAAAAATAAATESLPAETEKQQGVDAGAAGDPERLELEEQPKDVGRIPTPTRRHAPEEGEARVVRRLPPALPLAQPRPAARALSQLVKARGRSRSRVYRRSAGSMRPVTVDSSKARTSLDALKISLRQLRWKEFPFGRRLPCDIYWHGVSFRDSDILSGQVNKFPGPNGERR" } }, { "url": "https://www.uniprot.org/uniprot/A4Q9F4#F7BQM5-1", "isoform_ac": "F7BQM5-1", "locus": { "end_pos": 35752234, "strand": "+", "start_pos": 35940806, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUST00000160906", "id": "ENSMUST00000160906", "database": "Ensembl Transcript" }, { "url": "https://www.ensembl.org/id/ENSMUSP00000125511", "id": "ENSMUSP00000125511", "database": "Ensembl Peptide" } ] }, "sequence": { "header": "tr|F7BQM5-1|TTL11_MOUSE Computationally mapped isoform of Tubulin polyglutamylase TTLL11 OS=Mus musculus OX=10090 GN=Ttll11 PE=1 SV=1 CANONICAL=A4Q9F4-1", "length": 511, "sequence": "XMTEMVRKVTLSRALRIMQNLFPEEYNFYPRSWILPEEFQLFVSQVQTVKEGDPSWKPTFIVKPDSGCQGDGIYLIKDPCDGRLTGTLHNRPAVVQEYIRKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPNPQNLHHVFMHLTNYSLNIHSGKFVHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISLVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPMLLEVNANPSMRIEHEYELSPGVFENIPSLVDEEVKVAVIRDTLRLMDPLKKKKEIQSQQMEKSFTSKEDLNCDPTGGDSEPNPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGPTGFRTFIRNCKLSSSSLSMAAVDILYIDITRRWNSVTVDQRDSGMCLQAFVEAFFFLAQRKFKLQPLHEQVASLIDLCEYHLSVLDEKRLLCHRGRPLQRNPPQMNRPEHSATGSSAPRVIGASKLSQS" } } ], "pathway": [ { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:74410", "resource": "KEGG Pathway", "id": "mmu:74410", "name": "" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8955332", "resource": "Reactome", "id": "R-MMU-8955332", "name": "Carboxyterminal post-translational modifications of tubulin" } ], "function": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4#function", "annotation": "Polyglutamase which preferentially modifies alpha-tubulin (PubMed:17499049). Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. Required for CCSAP localization to both spindle and cilia microtubules (PubMed:17499049). Generates long side-chains (PubMed:20530212).", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4#function", "id": "A4Q9F4", "database": "UniProtKB" } ] } ], "orthologs": [ { "uniprot_canonical_ac": "Q8NHH1-1", "protein_name": "Tubulin polyglutamylase TTLL11", "sequence": { "length": 800, "sequence": "MAAAASVTGRVTWAASPMRSLGLGRRLSLPGPRLDAVTAAVNPSLSDHGNGLGRGTRGSGCSGGSLVADWGGGAAAAAAVALALAPALSTMRRGSSESELAARWEAEAVAAAKAAAKAEAEATAETVAEQVRVDAGAAGEPECKAGEEQPKVLAPAPAQPSAAEEGNTQVLQRPPPTLPPSKPKPVQGLCPHGKPRDKGRSCKRSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQLKWKEFPFGRRLPCDIYWHGVSFHDNDIFSGQVNKFPGMTEMVRKITLSRAVRTMQNLFPEEYNFYPRSWILPDEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIRLAGTLQSRPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIEHEHELSPGVFENVPSLVDEEVKVAVIRDTLRLMDPLKKKRENQSQQLEKPFAGKEDALDGELTSAPDCNANPEAHLPSICLKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGTMKLGPTGFRTFIRSCKLSSSSLSMAAVDILYIDITRRWNSMTLDQRDSGMCLQAFVEAFFFLAQRKFKMLPLHEQVASLIDLCEYHLSLLDEKRLVCGRGVPSGGRPPHRGPPQEPSPSAQPAGDNPPPRTSCANKLSHPRHTLS" }, "evidence": [ { "url": "http://www.informatics.jax.org/homology/77534", "id": "77534", "database": "MGI" } ], "common_name": "Human", "organism": "Homo sapiens", "tax_id": 9606 } ], "interactions": [], "synthesized_glycans": [], "snv": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "refseq": { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084050.1", "ac": "NP_084050.1", "name": "tubulin polyglutamylase TTLL11", "summary": "" }, "go_annotation": { "categories": [ { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "id": "A4Q9F4", "database": "UniProtKB" } ], "name": "ATP binding", "id": "GO:0005524" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "id": "A4Q9F4", "database": "UniProtKB" } ], "name": "ligase activity", "id": "GO:0016874" } ], "total": 2, "name": "Molecular Function" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "id": "A4Q9F4", "database": "UniProtKB" } ], "name": "cytoplasm", "id": "GO:0005737" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "id": "A4Q9F4", "database": "UniProtKB" } ], "name": "microtubule", "id": "GO:0005874" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "pmid": "", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "id": "A4Q9F4", "database": "UniProtKB" } ], "name": "cilium", "id": "GO:0005929" } ], "total": 3, "name": "Cellular Component" }, { "go_terms": [ { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051013", "pmid": "20530212", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "id": "A4Q9F4", "database": "UniProtKB" } ], "name": "microtubule severing", "id": "GO:0051013" }, { "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0018095", "pmid": "20530212", "evidence": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "id": "A4Q9F4", "database": "UniProtKB" } ], "name": "protein polyglutamylation", "id": "GO:0018095" } ], "total": 2, "name": "Biological Process" } ] }, "gene_names": [ { "url": "https://www.ncbi.nlm.nih.gov/protein/A4Q9F4", "type": "synonym", "resource": "RefSeq", "name": "4932702F08Rik; 4933424A20Rik; AU043211; D2Ertd624e" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A4Q9F4", "type": "synonym", "resource": "RefSeq", "name": "Ttll11" }, { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "type": "recommended", "resource": "UniProtKB", "name": "Ttll11" } ], "crossref": [ { "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000026885", "id": "ENSMUSG00000026885", "database": "Bgee" }, { "url": "https://www.ncbi.nlm.nih.gov/gene/74410", "id": "74410", "database": "GeneID" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR004344", "id": "IPR004344", "database": "InterPro" }, { "url": "https://www.ebi.ac.uk/interpro/entry/IPR013815", "id": "IPR013815", "database": "InterPro" }, { "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:74410", "id": "mmu:74410", "database": "KEGG Pathway" }, { "url": "http://www.informatics.jax.org/marker/MGI:1921660", "id": "1921660", "database": "MGI" }, { "url": "https://omabrowser.org/oma/group/CANKLSH/", "id": "CANKLSH", "database": "OMA" }, { "url": "http://www.orthodb.org/?query=1251554at2759", "id": "1251554at2759", "database": "OrthoDB" }, { "url": "http://pfam.xfam.org/family/PF03133", "id": "PF03133", "database": "Pfam" }, { "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A4Q9F4", "id": "PR_A4Q9F4", "database": "PRO" }, { "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-8955332", "id": "R-MMU-8955332", "database": "Reactome" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/NP_084050.1", "id": "NP_084050.1", "database": "RefSeq" } ], "expression_disease": [], "glycosylation": [], "mutagenesis": [], "disease": [], "phosphorylation": [], "mass": { "monoisotopic_mass": 82361.0, "chemical_mass": 82361.0 }, "expression_tissue": [], "gene": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "name": "Ttll11", "locus": { "end_pos": 35751241, "strand": "-", "start_pos": 35979913, "chromosome": "2", "evidence": [ { "url": "https://www.ensembl.org/id/ENSMUSG00000026885", "id": "ENSMUSG00000026885", "database": "Ensembl Gene" } ] } } ], "protein_names": [ { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "type": "synonym", "resource": "UniProtKB", "name": "6.-.-.-" }, { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "type": "recommended", "resource": "UniProtKB", "name": "Tubulin polyglutamylase TTLL11" }, { "url": "https://www.uniprot.org/uniprot/A4Q9F4", "type": "synonym", "resource": "UniProtKB", "name": "Tubulin--tyrosine ligase-like protein 11" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A4Q9F4", "type": "synonym", "resource": "RefSeq", "name": "polyglutamylase; tubulin--tyrosine ligase-like protein 11; ttll11" }, { "url": "https://www.ncbi.nlm.nih.gov/protein/A4Q9F4", "type": "synonym", "resource": "RefSeq", "name": "tubulin polyglutamylase TTLL11" } ] }