{
    "uniprot_canonical_ac": "A4D1Z8-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A4D1Z8-1|GRIFN_HUMAN Isoform 1 of Grifin  OS=Homo sapiens OX=9606 GN=GRIFIN PE=2 SV=4 CANONICAL=A4D1Z8-1", 
        "length": 144, 
        "sequence": "MAVQSKAFCAGGLAPGWKLLVQGHADSGEDRFETNFLLETGDIAFHIKPRFSSATVVGNAFQYGRWGPEQVSSIFPLAPGEPFEIEVSWDAEHFHVYAPEHKVLQFPCRQRPLGATTRVRVLSDHCLAQVELAKRGLSWGDRGY"
    }, 
    "uniprot_id": "GRIFN_HUMAN", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [], 
    "species": [
        {
            "common_name": "Human", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A4D1Z8", 
                    "id": "A4D1Z8", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Homo sapiens", 
            "taxid": 9606
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/18087242", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "18087242"
                }
            ], 
            "title": "A comparative gene expression profile of the whole eye from human, mouse, and guinea pig.", 
            "journal": "Mol. Vis.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A4D1Z8", 
                    "id": "A4D1Z8", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Hu S., Lu F., Wang W., Yu J., Zhang X., Zhou X., Yu X., Qu J., Jiang L., Yan D.", 
            "date": "2007"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/18448074", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "18448074"
                }
            ], 
            "title": "Unlike mammalian GRIFIN, the zebrafish homologue (DrGRIFIN) represents a functional carbohydrate-binding galectin.", 
            "journal": "Biochem. Biophys. Res. Commun.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A4D1Z8", 
                    "id": "A4D1Z8", 
                    "database": "UniProtKB"
                }
            ], 
            "authors": "Ahmed H., Vasta G.R.", 
            "date": "2008"
        }
    ], 
    "uniprot_ac": "A4D1Z8", 
    "site_annotation": [], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A4D1Z8#A4D1Z8-1", 
            "isoform_ac": "A4D1Z8-1", 
            "locus": {
                "end_pos": 2474873, 
                "strand": "+", 
                "start_pos": 2476383, 
                "chromosome": "7", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENST00000614228", 
                        "id": "ENST00000614228", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSP00000481185", 
                        "id": "ENSP00000481185", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A4D1Z8-1|GRIFN_HUMAN Isoform 1 of Grifin  OS=Homo sapiens OX=9606 GN=GRIFIN PE=2 SV=4 CANONICAL=A4D1Z8-1", 
                "length": 144, 
                "sequence": "MAVQSKAFCAGGLAPGWKLLVQGHADSGEDRFETNFLLETGDIAFHIKPRFSSATVVGNAFQYGRWGPEQVSSIFPLAPGEPFEIEVSWDAEHFHVYAPEHKVLQFPCRQRPLGATTRVRVLSDHCLAQVELAKRGLSWGDRGY"
            }
        }
    ], 
    "pathway": [], 
    "function": [], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q9D1U0-1", 
            "protein_name": "Grifin", 
            "sequence": {
                "length": 144, 
                "sequence": "MTLQFEAFCAGGLAPGWSLTVQGHADAGEEKFEINFLTDAGDIAFHVKPRFSSATVVGNAFQGGRWGQEEVSSIFPLTLGEPFEMEVSADAEHFHIYAQEQKVLQFPHRHRPLATITRVRVLSEHRLAQVELAKRSLSWGDGGY"
            }, 
            "evidence": [
                {
                    "url": "https://omabrowser.org/oma/group/A4D1Z8/", 
                    "id": "A4D1Z8", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Mouse", 
            "organism": "Mus musculus", 
            "tax_id": 10090
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }
    ], 
    "refseq": {}, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", 
                        "pmid": "", 
                        "evidence": [
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                                "url": "https://www.uniprot.org/uniprot/A4D1Z8", 
                                "id": "A4D1Z8", 
                                "database": "UniProtKB"
                            }
                        ], 
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                        "id": "GO:0030246"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "21873635", 
                        "evidence": [
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                                "url": "https://www.uniprot.org/uniprot/A4D1Z8", 
                                "id": "A4D1Z8", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }
        ]
    }, 
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        {
            "url": "https://www.uniprot.org/uniprot/A4D1Z8", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "GRIFIN"
        }
    ], 
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        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSG00000275572", 
            "id": "ENSG00000275572", 
            "database": "Bgee"
        }, 
        {
            "url": "https://hive.biochemistry.gwu.edu/biomuta/proteinview/A4D1Z8", 
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            "database": "BioMuta"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00070", 
            "id": "cd00070", 
            "database": "CDD"
        }, 
        {
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            "id": "GRIFIN", 
            "database": "GeneCards"
        }, 
        {
            "url": "https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=4577", 
            "id": "4577", 
            "database": "HGNC"
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        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001079", 
            "id": "IPR001079", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", 
            "id": "IPR013320", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR030641", 
            "id": "IPR030641", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.nextprot.org/entry/NX_A4D1Z8", 
            "id": "NX_A4D1Z8", 
            "database": "neXtProt"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/CPGWSVI/", 
            "id": "CPGWSVI", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11346:SF21", 
            "id": "PTHR11346:SF21", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF00337", 
            "id": "PF00337", 
            "database": "Pfam"
        }, 
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            "database": "PHAROS"
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            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A4D1Z8", 
            "id": "PR_A4D1Z8", 
            "database": "PRO"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
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        {
            "residue": "Ser", 
            "position": "138", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A4D1Z8", 
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            ], 
            "kinase_uniprot_canonical_ac": "", 
            "kinase_gene_name": ""
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        "monoisotopic_mass": 15999.0, 
        "chemical_mass": 15999.0
    }, 
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    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A4D1Z8", 
            "name": "GRIFIN", 
            "locus": {
                "end_pos": 2474844, 
                "strand": "-", 
                "start_pos": 2476894, 
                "chromosome": "7", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSG00000275572", 
                        "id": "ENSG00000275572", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A4D1Z8", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "Galectin-related inter-fiber protein"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A4D1Z8", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Grifin"
        }
    ]
}