{
    "uniprot_canonical_ac": "A2VDH3-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A2VDH3-1|LRC38_MOUSE Isoform 1 of Leucine-rich repeat-containing protein 38  OS=Mus musculus OX=10090 GN=Lrrc38 PE=2 SV=2 CANONICAL=A2VDH3-1", 
        "length": 298, 
        "sequence": "MSLCVAPRHPTGAAAALGLGSLLVLLGPGRACPAGCACTDPHTVDCRDRGLPSVPDPFPLDVRKLLVAGNRIQQIPEDFFIFHGDLVYLDFRNNSLRSLEEGTFSGSGKLAFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNHLAGVHEAAFESLESLQVLELNDNNLRSLNVAALDALPALRTVRLDGNPWLCDCDFAHLFSWIQENTSKLPKGLDAIQCSLPMEDRRVALRELSEASFSECKFSLSLTDLFIIIFSGVAVSIAAIISSFFLATVVQCFQRCAPNKDTEDEDDDEDD"
    }, 
    "uniprot_id": "LRC38_MOUSE", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [
        "glycoprotein", 
        "predicted.uniprotkb_gly"
    ], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2VDH3", 
                    "id": "A2VDH3", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "publication": [], 
    "uniprot_ac": "A2VDH3", 
    "site_annotation": [
        {
            "end_pos": 121, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 119
        }, 
        {
            "end_pos": 210, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 208
        }, 
        {
            "end_pos": 95, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 93
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2VDH3#A2VDH3-1", 
            "isoform_ac": "A2VDH3-1", 
            "locus": {
                "end_pos": 143350169, 
                "strand": "-", 
                "start_pos": 143370014, 
                "chromosome": "CHR_MG4136_PATCH", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000181564", 
                        "id": "ENSMUST00000181564", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000137856", 
                        "id": "ENSMUSP00000137856", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2VDH3-1|LRC38_MOUSE Isoform 1 of Leucine-rich repeat-containing protein 38  OS=Mus musculus OX=10090 GN=Lrrc38 PE=2 SV=2 CANONICAL=A2VDH3-1", 
                "length": 298, 
                "sequence": "MSLCVAPRHPTGAAAALGLGSLLVLLGPGRACPAGCACTDPHTVDCRDRGLPSVPDPFPLDVRKLLVAGNRIQQIPEDFFIFHGDLVYLDFRNNSLRSLEEGTFSGSGKLAFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNHLAGVHEAAFESLESLQVLELNDNNLRSLNVAALDALPALRTVRLDGNPWLCDCDFAHLFSWIQENTSKLPKGLDAIQCSLPMEDRRVALRELSEASFSECKFSLSLTDLFIIIFSGVAVSIAAIISSFFLATVVQCFQRCAPNKDTEDEDDDEDD"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:242735", 
            "resource": "KEGG Pathway", 
            "id": "mmu:242735", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.uniprot.org/uniprot/A2VDH3#function", 
            "annotation": "Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium (By similarity).", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2VDH3#function", 
                    "id": "A2VDH3", 
                    "database": "UniProtKB"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q5VT99-1", 
            "protein_name": "Leucine-rich repeat-containing protein 38", 
            "sequence": {
                "length": 294, 
                "sequence": "MRPRAPACAAAALGLCSLLLLLAPGHACPAGCACTDPHTVDCRDRGLPSVPDPFPLDVRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVFLDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLSVAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQENASKLPKGLDEIQCSLPMESRRISLRELSEASFSECRFSLSLTDLCIIIFSGVAVSIAAIISSFFLATVVQCLQRCAPNKDAEDEDEDKDD"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/77949", 
                    "id": "77949", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156455.1", 
        "ac": "NP_001156455.1", 
        "name": "leucine-rich repeat-containing protein 38 precursor", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2VDH3", 
                                "id": "A2VDH3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "ion channel binding", 
                        "id": "GO:0044325"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2VDH3", 
                                "id": "A2VDH3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "voltage-gated potassium channel activity", 
                        "id": "GO:0005249"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099104", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2VDH3", 
                                "id": "A2VDH3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "potassium channel activator activity", 
                        "id": "GO:0099104"
                    }
                ], 
                "total": 3, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2VDH3", 
                                "id": "A2VDH3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "voltage-gated potassium channel complex", 
                        "id": "GO:0008076"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903818", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2VDH3", 
                                "id": "A2VDH3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "positive regulation of voltage-gated potassium channel activity", 
                        "id": "GO:1903818"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2VDH3", 
                                "id": "A2VDH3", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "potassium ion transmembrane transport", 
                        "id": "GO:0071805"
                    }
                ], 
                "total": 2, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2VDH3", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "A230053A07Rik"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2VDH3", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Lrrc38"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2VDH3", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Lrrc38"
        }
    ], 
    "crossref": [
        {
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000028584", 
            "id": "ENSMUSG00000028584", 
            "database": "Bgee"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/242735", 
            "id": "242735", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", 
            "id": "IPR000372", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", 
            "id": "IPR000483", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", 
            "id": "IPR001611", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", 
            "id": "IPR003591", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", 
            "id": "IPR032675", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:242735", 
            "id": "mmu:242735", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:2442845", 
            "id": "2442845", 
            "database": "MGI"
        }, 
        {
            "url": "https://omabrowser.org/oma/group/KGTFGES/", 
            "id": "KGTFGES", 
            "database": "OMA"
        }, 
        {
            "url": "http://www.orthodb.org/?query=826997at2759", 
            "id": "826997at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF13855", 
            "id": "PF13855", 
            "database": "Pfam"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2VDH3", 
            "id": "PR_A2VDH3", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001156455.1", 
            "id": "NP_001156455.1", 
            "database": "RefSeq"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [
        {
            "residue": "Asn", 
            "site_category": "predicted", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2VDH3#ptm_processing", 
                    "id": "A2VDH3", 
                    "database": "UniProtKB"
                }
            ], 
            "subtype": "", 
            "relation": "attached", 
            "position": 119, 
            "glytoucan_ac": "", 
            "type": "N-linked"
        }
    ], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 32343.0, 
        "chemical_mass": 32343.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2VDH3", 
            "name": "Lrrc38", 
            "locus": {
                "end_pos": 143371032, 
                "strand": "+", 
                "start_pos": 143349757, 
                "chromosome": "4", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000028584", 
                        "id": "ENSMUSG00000028584", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2VDH3", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "BK channel auxiliary gamma subunit LRRC38"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2VDH3", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Leucine-rich repeat-containing protein 38"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2VDH3", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "leucine-rich repeat-containing protein 38 precursor"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2VDH3", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "leucine-rich repeat-containing protein 38; BK channel auxilliary gamma subunit LRRC38; BK channel auxiliary gamma subunit LRRC38"
        }
    ]
}