{
    "uniprot_canonical_ac": "A2RSQ1-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A2RSQ1-1|GLBL3_MOUSE Isoform 1 of Beta-galactosidase-1-like protein 3  OS=Mus musculus OX=10090 GN=Glb1l3 PE=1 SV=1 CANONICAL=A2RSQ1-1", 
        "length": 649, 
        "sequence": "MAIFFLPTVLSGFAPHSEEVFKSPARFSWSNLTPSELKNRFVGLSTKTNALGKAYFTLEGHKFMIVGGSIHYFRVPREYWKDRLLKLQACGFNTVTTYIPWNLHEQERGKFDFSEILDLEAYVLLAKTIGLWVILRPGPYICAEVDLGGLPSWLLRNPVTDLRTTNKGFIEAVDKYFDHLIPKILPLQYRHGGPVIAVQVENEYGSFQKDRNYMNYLKKALLKRGIVELLLTSDDKDGIQIGSVNGALTTINMNSFTKDSFIKLHKMQSDKPIMIMEYWTGWYDSWGSKHIEKSAEEIRHTVYKFISYGLSFNMYMFHGGTNFGFINGGRYENHHISVVTSYDYDAVLSEAGDYTEKYFKLRKLFASGSARPLPPLPPLIPKAIYPSVNLSFYLPLFDILPYLNQPVMLHTPVTMENLPINNGSGQPFGLVLYETSICSGGSLFASVHDSAQVFLNDQSIGILDENHEVLQIPKIQGCQLLRILVENQGRINYSWRIQSEQKGLKEVVSIDGLLLTNFTIYSLDMKMSFFKRLRSASWRLAPKTYNGPAFYWGILNAGSSPTDTFLHLPNWHYGFVFINGRNLGRYWDIGPQRTLYLPGPWLHPEDNEVIVFEKIEKGFDIQTRKKPQLQECYETGSGLPDAAGDADPC"
    }, 
    "uniprot_id": "GLBL3_MOUSE", 
    "enzyme_annotation": [
        {
            "ec": "3.2.1.-", 
            "activity": ""
        }
    ], 
    "glycation": [], 
    "keywords": [
        "enzyme", 
        "glycohydrolase-activity"
    ], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2RSQ1", 
                    "id": "A2RSQ1", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/21633714", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "21633714"
                }
            ], 
            "title": "Altered expression of beta-galactosidase-1-like protein 3 (Glb1l3) in the retinal pigment epithelium (RPE)-specific 65-kDa protein knock-out mouse model of Leber's congenital amaurosis.", 
            "journal": "Molecular vision", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106794.1", 
                    "id": "NP_001106794.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Le Carre J, Schorderet DF, Cottet S", 
            "date": "2011"
        }
    ], 
    "uniprot_ac": "A2RSQ1", 
    "site_annotation": [
        {
            "end_pos": 33, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 31
        }, 
        {
            "end_pos": 391, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 389
        }, 
        {
            "end_pos": 424, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 422
        }, 
        {
            "end_pos": 494, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 492
        }, 
        {
            "end_pos": 519, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 517
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RSQ1#A0A1B0GSK9-1", 
            "isoform_ac": "A0A1B0GSK9-1", 
            "locus": {
                "end_pos": 26818184, 
                "strand": "+", 
                "start_pos": 26860575, 
                "chromosome": "9", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000210274", 
                        "id": "ENSMUST00000210274", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000147979", 
                        "id": "ENSMUSP00000147979", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|A0A1B0GSK9-1|GLBL3_MOUSE Computationally mapped isoform of Beta-galactosidase-1-like protein 3  OS=Mus musculus OX=10090 GN=Glb1l3 PE=1 SV=1 CANONICAL=A2RSQ1-1", 
                "length": 662, 
                "sequence": "MAYLSKHRSWKKFMAIFFLPTVLSGFAPHSEEVFKSPARFSWSNLTPSELKNRFVGLSTKTNALGKAYFTLEGHKFMIVGGSIHYFRVPREYWKDRLLKLQACGFNTVTTYIPWNLHEQERGKFDFSEILDLEAYVLLAKTIGLWVILRPGPYICAEVDLGGLPSWLLRNPVTDLRTTNKGFIEAVDKYFDHLIPKILPLQYRHGGPVIAVQVENEYGSFQKDRNYMNYLKKALLKRGIVELLLTSDDKDGIQIGSVNGALTTINMNSFTKDSFIKLHKMQSDKPIMIMEYWTGWYDSWGSKHIEKSAEEIRHTVYKFISYGLSFNMYMFHGGTNFGFINGGRYENHHISVVTSYDYDAVLSEAGDYTEKYFKLRKLFASGSARPLPPLPPLIPKAIYPSVNLSFYLPLFDILPYLNQPVMLHTPVTMENLPINNGSGQPFGLVLYETSICSGGSLFASVHDSAQVFLNDQSIGILDENHEVLQIPKIQGCQLLRILVENQGRINYSWRIQSEQKGLKEVVSIDGLLLTNFTIYSLDMKMSFFKRLRSASWRLAPKTYNGPAFYWGILNAGSSPTDTFLHLPNWHYGFVFINGRNLGRYWDIGPQRTLYLPGPWLHPEDNEVIVFEKIEKGFDIQTRKKPQLQECYETGSGLPDAAGDADPC"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RSQ1#A2RSQ1-1", 
            "isoform_ac": "A2RSQ1-1", 
            "locus": {}, 
            "sequence": {
                "header": "sp|A2RSQ1-1|GLBL3_MOUSE Isoform 1 of Beta-galactosidase-1-like protein 3  OS=Mus musculus OX=10090 GN=Glb1l3 PE=1 SV=1 CANONICAL=A2RSQ1-1", 
                "length": 649, 
                "sequence": "MAIFFLPTVLSGFAPHSEEVFKSPARFSWSNLTPSELKNRFVGLSTKTNALGKAYFTLEGHKFMIVGGSIHYFRVPREYWKDRLLKLQACGFNTVTTYIPWNLHEQERGKFDFSEILDLEAYVLLAKTIGLWVILRPGPYICAEVDLGGLPSWLLRNPVTDLRTTNKGFIEAVDKYFDHLIPKILPLQYRHGGPVIAVQVENEYGSFQKDRNYMNYLKKALLKRGIVELLLTSDDKDGIQIGSVNGALTTINMNSFTKDSFIKLHKMQSDKPIMIMEYWTGWYDSWGSKHIEKSAEEIRHTVYKFISYGLSFNMYMFHGGTNFGFINGGRYENHHISVVTSYDYDAVLSEAGDYTEKYFKLRKLFASGSARPLPPLPPLIPKAIYPSVNLSFYLPLFDILPYLNQPVMLHTPVTMENLPINNGSGQPFGLVLYETSICSGGSLFASVHDSAQVFLNDQSIGILDENHEVLQIPKIQGCQLLRILVENQGRINYSWRIQSEQKGLKEVVSIDGLLLTNFTIYSLDMKMSFFKRLRSASWRLAPKTYNGPAFYWGILNAGSSPTDTFLHLPNWHYGFVFINGRNLGRYWDIGPQRTLYLPGPWLHPEDNEVIVFEKIEKGFDIQTRKKPQLQECYETGSGLPDAAGDADPC"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RSQ1#A2RSQ1-2", 
            "isoform_ac": "A2RSQ1-2", 
            "locus": {}, 
            "sequence": {
                "header": "sp|A2RSQ1-2|GLBL3_MOUSE Isoform 2 of Beta-galactosidase-1-like protein 3  OS=Mus musculus OX=10090 GN=Glb1l3 PE=1 SV=1 CANONICAL=A2RSQ1-1", 
                "length": 586, 
                "sequence": "MIVGGSIHYFRVPREYWKDRLLKLQACGFNTVTTYIPWNLHEQERGKFDFSEILDLEAYVLLAKTIGLWVILRPGPYICAEVDLGGLPSWLLRNPVTDLRTTNKGFIEAVDKYFDHLIPKILPLQYRHGGPVIAVQVENEYGSFQKDRNYMNYLKKALLKRGIVELLLTSDDKDGIQIGSVNGALTTINMNSFTKDSFIKLHKMQSDKPIMIMEYWTGWYDSWGSKHIEKSAEEIRHTVYKFISYGLSFNMYMFHGGTNFGFINGGRYENHHISVVTSYDYDAVLSEAGDYTEKYFKLRKLFASGSARPLPPLPPLIPKAIYPSVNLSFYLPLFDILPYLNQPVMLHTPVTMENLPINNGSGQPFGLVLYETSICSGGSLFASVHDSAQVFLNDQSIGILDENHEVLQIPKIQGCQLLRILVENQGRINYSWRIQSEQKGLKEVVSIDGLLLTNFTIYSLDMKMSFFKRLRSASWRLAPKTYNGPAFYWGILNAGSSPTDTFLHLPNWHYGFVFINGRNLGRYWDIGPQRTLYLPGPWLHPEDNEVIVFEKIEKGFDIQTRKKPQLQECYETGSGLPDAAGDADPC"
            }
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RSQ1#F8WIH9-1", 
            "isoform_ac": "F8WIH9-1", 
            "locus": {
                "end_pos": 26818184, 
                "strand": "+", 
                "start_pos": 26859540, 
                "chromosome": "9", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000034448", 
                        "id": "ENSMUST00000034448", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000034448", 
                        "id": "ENSMUSP00000034448", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "tr|F8WIH9-1|GLBL3_MOUSE Computationally mapped isoform of Beta-galactosidase-1-like protein 3  OS=Mus musculus OX=10090 GN=Glb1l3 PE=1 SV=1 CANONICAL=A2RSQ1-1", 
                "length": 587, 
                "sequence": "MIVGGSIHYFRVPREYWKDRLLKLQACGFNTVTTYIPWNLHEQERGKFDFSEILDLEAYVLLAKTIGLWVILRPGPYICAEVDLGGLPSWLLRNPVTDLRTTNKGFIEAVDKYFDHLIPKILPLQYRHGGPVIAVQVENEYGSFQKDRNYMNYLKKALLKRGIVELLLTSDDKDGIQIGSVNGALTTINMNSFTKDSFIKLHKMQSDKPIMIMEYWTGWYDSWGSKHIEKSAEEIRHTVYKFISYGLSFNMYMFHGGTNFGFINGGRYENHHISVVTSYDYDAVLSEAGDYTEKYFKLRKLFASGSARPLPPLPPLIPKAIYPSVNLSFYLPLFDILPYLNQPVMLHTPVTMENLPINNGSGQPFGLVLYETSICSGGSLFASVHDSAQVFLNDQSIGILDENHEVLQIPKIQQGCQLLRILVENQGRINYSWRIQSEQKGLKEVVSIDGLLLTNFTIYSLDMKMSFFKRLRSASWRLAPKTYNGPAFYWGILNAGSSPTDTFLHLPNWHYGFVFINGRNLGRYWDIGPQRTLYLPGPWLHPEDNEVIVFEKIEKGFDIQTRKKPQLQECYETGSGLPDAAGDADPC"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:70893", 
            "resource": "KEGG Pathway", 
            "id": "mmu:70893", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106794.1", 
            "annotation": "Early-onset downregulation of Glb1l3 in Rpe65-related disease. Impaired expression of Glb1l3 is mostly due to absence of chromophore 11-cis retinal.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106794.1", 
                    "id": "NP_001106794.1", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q5XIL5-1", 
            "protein_name": "Beta-galactosidase-1-like protein 3", 
            "sequence": {
                "length": 631, 
                "sequence": "MAIFFLPLVLPGFAPRSEDSFKSPARFSWSYLNPSKLKKRSVGLSTETNAHGQAYFTLEGHKFMIVGGSIHYFRVPREYWKDRLLKLQACGFNTVTTYIPWNLHEQERGKFDFSEILDLEAYVLLAKTLGLWVILRPGPYICAEVDLGGLPSWLLRNPGSNLRTTNKDFIEAVDKYFDHLIPKILPLQYRRGGPVIAVQVENEYGSFRNDKNYMEYIKKALLNRGIVELLLTSDNESGIRIGSVKGALATINVNSFIKDSFVKLHRMQNDKPIMIMEYWTGWYDSWGSKHTEKSANEIRRTIYRFFSYGLSFNVYMFHGGTNFGFINGGYHENGHTNVVTSYDYDAVLSEAGDYTEKYFKLRKLFASGSARPLPPLPRLIPKAVYPSVNLSFYLPLFDILPYLNKPVMLETPVTMENLPINNGSGQPFGLVLYETSICFGGGLSASVHDSAQVFLNDKSIGILDENNEFLHIPKIQGCQLLRILVENQGRINFSWRIQSEQKGLNEAVTINGTLLRNFTIYSLDMKMSFFERLRSASWRIAPKTYKGPAFYWGSLNVGSFPTDTFLHLPNWHYGFVFINGRNLGRYWDIGPQKTLYLPGPWLHPEDNDVIVFEKIEKGFYIQTRKKPQLQN"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/72240", 
                    "id": "72240", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Rat", 
            "organism": "Rattus norvegicus", 
            "tax_id": 10116
        }, 
        {
            "uniprot_canonical_ac": "Q8NCI6-1", 
            "protein_name": "Beta-galactosidase-1-like protein 3", 
            "sequence": {
                "length": 653, 
                "sequence": "MKSPPLLSPCLSWKRMAGIFFLPFISSGFAPRFKQEENFMLGRAHPSQPRFNWSHLTPLELKNRSVGLGTESTGRGKPHFTLEGHKFLIFGGSIHYFRVPREYWRDRLLKLKACGFNTVTTYVPWNLHEPERGKFDFSGNLDLEAFVLMAAEIGLWVILRPGRYICSEMDLGGLPSWLLQDPRLLLRTTNKSFIEAVEKYFDHLIPRVIPLQYRQAGPVIAVQVENEYGSFNKDKTYMPYLHKALLRRGIVELLLTSDGEKHVLSGHTKGVLAAINLQKLHQDTFNQLHKVQRDKPLLIMEYWVGWFDRWGDKHHVKDAKEVEHAVSEFIKYEISFNVYMFHGGTNFGFMNGATYFGKHSGIVTSYDYDAVLTEAGDYTEKYLKLQKLFQSVSATPLPRVPKLPPKAVYPPVRPSLYLPLWDALSYLNEPVRSRQPVNMENLPINNGSGQSYGLVLYEKSICSGGRLRAHAHDVAQVFLDETMIGILNENNKDLHIPELRDCRYLRILVENQGRVNFSWQIQNEQKGITGSVSINNSSLEGFTIYSLEMKMSFFERLRSATWKPVPDSHQGPAFYCGTLKAGPSPKDTFLSLLNWNYGFVFINGRNLGRYWNIGPQKTLYLPGVWLHPEDNEVILFEKMMSGSDIKSTDKPTL"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/72240", 
                    "id": "72240", 
                    "database": "MGI"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb", 
            "label": "Isoforms"
        }, 
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106794.1", 
        "ac": "NP_001106794.1", 
        "name": "beta-galactosidase-1-like protein 3 precursor", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004565", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RSQ1", 
                                "id": "A2RSQ1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "beta-galactosidase activity", 
                        "id": "GO:0004565"
                    }
                ], 
                "total": 1, 
                "name": "Molecular Function"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", 
                        "pmid": "21873635", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RSQ1", 
                                "id": "A2RSQ1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "vacuole", 
                        "id": "GO:0005773"
                    }
                ], 
                "total": 1, 
                "name": "Cellular Component"
            }, 
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2RSQ1", 
                                "id": "A2RSQ1", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "carbohydrate metabolic process", 
                        "id": "GO:0005975"
                    }
                ], 
                "total": 1, 
                "name": "Biological Process"
            }
        ]
    }, 
    "gene_names": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2RSQ1", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "4921509F24Rik"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2RSQ1", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "Glb1l3"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RSQ1", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Glb1l3"
        }
    ], 
    "crossref": [
        {
            "url": "http://www.cazy.org/fam/GH35.html", 
            "id": "GH35", 
            "database": "CAZy"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/gene/70893", 
            "id": "70893", 
            "database": "GeneID"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR001944", 
            "id": "IPR001944", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", 
            "id": "IPR008979", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", 
            "id": "IPR017853", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR019801", 
            "id": "IPR019801", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR026283", 
            "id": "IPR026283", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR031330", 
            "id": "IPR031330", 
            "database": "InterPro"
        }, 
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:70893", 
            "id": "mmu:70893", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:1918143", 
            "id": "1918143", 
            "database": "MGI"
        }, 
        {
            "url": "http://www.orthodb.org/?query=179316at2759", 
            "id": "179316at2759", 
            "database": "OrthoDB"
        }, 
        {
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23421", 
            "id": "PTHR23421", 
            "database": "PANTHER"
        }, 
        {
            "url": "http://pfam.xfam.org/family/PF01301", 
            "id": "PF01301", 
            "database": "Pfam"
        }, 
        {
            "url": "http://research.bioinformatics.udel.edu/pro/entry/PR_A2RSQ1", 
            "id": "PR_A2RSQ1", 
            "database": "PRO"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106794.1", 
            "id": "NP_001106794.1", 
            "database": "RefSeq"
        }
    ], 
    "expression_disease": [], 
    "glycosylation": [], 
    "mutagenesis": [], 
    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 73922.0, 
        "chemical_mass": 73922.0
    }, 
    "expression_tissue": [], 
    "gene": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RSQ1", 
            "name": "Glb1l3", 
            "locus": {
                "end_pos": 26817953, 
                "strand": "-", 
                "start_pos": 26860890, 
                "chromosome": "9", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSG00000031966", 
                        "id": "ENSMUSG00000031966", 
                        "database": "Ensembl Gene"
                    }
                ]
            }
        }
    ], 
    "protein_names": [
        {
            "url": "https://www.uniprot.org/uniprot/A2RSQ1", 
            "type": "synonym", 
            "resource": "UniProtKB", 
            "name": "3.2.1.-"
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2RSQ1", 
            "type": "recommended", 
            "resource": "UniProtKB", 
            "name": "Beta-galactosidase-1-like protein 3"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2RSQ1", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "beta-galactosidase-1-like protein 3 precursor"
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/A2RSQ1", 
            "type": "synonym", 
            "resource": "RefSeq", 
            "name": "beta-galactosidase-1-like protein 3"
        }
    ]
}