{
    "uniprot_canonical_ac": "A2AJX4-1", 
    "ptm_annotation": [], 
    "sequence": {
        "header": "sp|A2AJX4-1|MALR1_MOUSE Isoform 1 of MAM and LDL-receptor class A domain-containing protein 1  OS=Mus musculus OX=10090 GN=Malrd1 PE=1 SV=2 CANONICAL=A2AJX4-1", 
        "length": 2123, 
        "sequence": "MFLPKAAVSAFSMHGSLCFLWTVCLSISPLSQQGVQAFQCSNGVSLPSDYVCDFTDHCGDNSEEQQCWSYGRCNFEDRLCSMTEDQTLQPGWTRRSGIISNSPPFWDHNGNISAHFLALVSRVDSISSNLRSRIFLPTNDQQVCQITFYNFSSNQNGKLIAGLQTLCGDPIEHLWQKTEILQSRWERNVITVQSSQQFQVIFQAQMLATHGQEEVIAIDDISFSSGCLPADVCQTCGFDLDTCGLATEASAGRTSWMCTKVREIPSLDSVPWQDQRGHDEGSFVWMRAGHASVSRLVESSAYLNSSVCHCMDGNCRLQFNYTMENSILRVRLYNDKEEKKTWTFNTSTYSTWMKADVLIPEDLKAFKVVLEGTVLSQKSFIGIDQLLVYNFGQTHSQKLCSVNEYTPASRQCLTHSSVCDSGMDHSNGIDEDSEACASLLTWDFESGFCGWEPFPTEDSHWEVVRGLSNGEHLFLEAGHTVSRNQGSFIYFGPQKSTAVARLGSPILTKSLTTFTPCQVRFWYHLSEHSSLSVFTRTSVDGSLLKQSEVTQFSDSQWSQAKVDLHAKAEESTLPFQLVLEATILSSNATVAVDDISISHECEISYKSLRSTSIQNKVADCDFEANSCGWFEASGGDHFDWVWSSQSNLSADLEQQAPPRDHTHGTAQGHFMFILKTSNSLFQTAKLQSPTFSQTGPGCTMSFWFYNYGLSVGAAELQLHLENSRDTTALWRVLYNQGNQWSEATVQLGRLTQPFYLSLEKVSLAVYSGVSAVDDIHFENCALPPPVESCDEPDHFWCRQTKACIGRHQLCDLVDDCGDYTDETGCAPGLQCNFENGICNWEQSTKDDFNWTRYQGPTSTMNTGPMKDHTLGTAKGHYLYIETSGPQGFQDKAVLLSPILNATEAKVCTFRLYYHMFGKHIYRLAIYQRIWSNTKGQLLWQIFGDQGNRWIRKDLSITSRKPFQILIMASVGDGFTGDIAIDDLSFMDCTLYPDNLPMDIPSPPETSVPVTLPPNNCTDDQFVCRSNGHCVGNIQKCDFRYDCIDKSDESSCVLEVCTFEERKLCKWYQPIPANSLHDSNTFRWGLGNGISIHHGEENHRPSVDHTKNTTDGWYLYADSSNGKFGDLADIVTPVISLMGPRCTLVFWTYMNGATVGSLQVLIKMGNTISKVWAQSGQQGPQWKKAEVFLGIHSHVEIVFRAKRGVSYIGDVAVDDVSFQNCSPLLSTNRKCTTDEFMCANKHCIEKDKLCDFVNDCADNSDETTFICGTSSGRCDFEFDLCTWEQDQDEDIDWNLKASNIPATSTEPAVDHTLGNSSGHYIILKSFFPQQPVKTGRISSPVISKRSKDCKIIFNYHMYGSGIAALLLLQVTVTNHTRVLLNLTKEQGNFWQRKELSLSSDEDFRVKFEGRVGEGIRGNIALDDIVLTKSCLPSHHSTREEPAFPLPTGFCPRGYEECQNGRCYSPEQRCNFVDDCGDNSDENECGGSCTFEKGWCGWKNSLAENSDWVLGIGSYKSQRPPKDHTLGNEHGHFMYLEATPVGLHGDKAHFKSATWQESSAACTMSFWYFISAKATGSIQILIKTDKGLWEVWQQSKPDPGNHWRRATILLGKLRNFEVIFQGIRTRDLGGGAAIDDIEFNNCTTVGETTDICSEETDFLCQDKKCIASHLVCDYKPDCSDTSDEAHCGYYTSTAGSCNFETTSGDWTVECGLTQDPEDDLDWSIGSIIPTEGLSRDSDHTPGSGRHFLYVNTSLAEEGSTARIITSHFFPASLGICTVRFWFYMVDPHIVGILKVYLIEKSGLNILMWSMMRNKNTGWTYAHVPLSSNSPFKVAFEADLGGKEDIFIALDDITFTPTCASGGPALPQPPLCEEGQFACIYALQCVSASEKCDGQEDCIDGSDEMNCSLGPSPQPCSDTEFQCFESQCIPSLLLCDGVADCQFNEDESSCVNQSCPSGALACNSSGLCIPAHQRCDGTAHCKDIQVDESSCSECPIHYCRNGGTCVIENIGPTCRCVQGWTGNRCHIRSNLSTEGSVHTQNYIWTLLGIGLGFLLTHIAVAILCSLGIRRRPMRKSEGVGNHSFINPVYRNCINQEKTQSSIYSFPNPFYGAASGSLETVSHHLKS"
    }, 
    "uniprot_id": "MALR1_MOUSE", 
    "enzyme_annotation": [], 
    "glycation": [], 
    "keywords": [
        "glycoprotein", 
        "predicted.uniprotkb_gly"
    ], 
    "species": [
        {
            "common_name": "Mouse", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AJX4", 
                    "id": "A2AJX4", 
                    "database": "UniProtKB"
                }
            ], 
            "name": "Mus musculus", 
            "taxid": 10090
        }
    ], 
    "publication": [
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/10744778", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "10744778"
                }
            ], 
            "title": "A locus conferring resistance to diet-induced hypercholesterolemia and atherosclerosis on mouse chromosome 2.", 
            "journal": "J. Lipid Res.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AJX4", 
                    "id": "A2AJX4", 
                    "database": "UniProtKB"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297384.1", 
                    "id": "NP_001297384.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Choi J., Wang X., Davis R.C., Lusis A.J., Reue K., Allayee H., Phan J., Castellani L.W., Mouzeyan A., Sinsheimer J.", 
            "date": "2000"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/11682476", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "11682476"
                }
            ], 
            "title": "The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.", 
            "journal": "The Journal of biological chemistry", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297384.1", 
                    "id": "NP_001297384.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Phan J, Pesaran T, Davis RC, Reue K", 
            "date": "2002"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/23747249", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "23747249"
                }
            ], 
            "title": "Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels.", 
            "journal": "Cell Metab.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AJX4", 
                    "id": "A2AJX4", 
                    "database": "UniProtKB"
                }, 
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297384.1", 
                    "id": "NP_001297384.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Lee J.M., Reue K., Auwerx J., Chin R.G., Vergnes L.", 
            "date": "2013"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/26045262", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "26045262"
                }
            ], 
            "title": "Diet1 is a regulator of fibroblast growth factor 15/19-dependent bile acid synthesis.", 
            "journal": "Digestive diseases (Basel, Switzerland)", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297384.1", 
                    "id": "NP_001297384.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Reue K, Lee JM, Vergnes L", 
            "date": "2015"
        }, 
        {
            "reference": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/pubmed/29295820", 
                    "type": [
                        "PubMed"
                    ], 
                    "id": "29295820"
                }
            ], 
            "title": "Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants.", 
            "journal": "Journal of lipid research", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297384.1", 
                    "id": "NP_001297384.1", 
                    "database": "RefSeq"
                }
            ], 
            "authors": "Lee JM, Ong JR, Vergnes L, de Aguiar Vallim TQ, Nolan J, Cantor RM, Walters JRF, Reue K", 
            "date": "2018"
        }
    ], 
    "uniprot_ac": "A2AJX4", 
    "site_annotation": [
        {
            "end_pos": 1017, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1015
        }, 
        {
            "end_pos": 1109, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1107
        }, 
        {
            "end_pos": 113, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 111
        }, 
        {
            "end_pos": 1221, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1219
        }, 
        {
            "end_pos": 1316, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1314
        }, 
        {
            "end_pos": 1375, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1373
        }, 
        {
            "end_pos": 1382, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1380
        }, 
        {
            "end_pos": 152, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 150
        }, 
        {
            "end_pos": 1641, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1639
        }, 
        {
            "end_pos": 1751, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1749
        }, 
        {
            "end_pos": 1905, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1903
        }, 
        {
            "end_pos": 1951, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1949
        }, 
        {
            "end_pos": 1962, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 1960
        }, 
        {
            "end_pos": 2029, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 2027
        }, 
        {
            "end_pos": 2080, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 2078
        }, 
        {
            "end_pos": 306, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 304
        }, 
        {
            "end_pos": 322, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 320
        }, 
        {
            "end_pos": 347, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 345
        }, 
        {
            "end_pos": 589, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 587
        }, 
        {
            "end_pos": 649, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 647
        }, 
        {
            "end_pos": 851, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 849
        }, 
        {
            "end_pos": 902, 
            "annotation": "n_glycosylation_sequon", 
            "start_pos": 900
        }
    ], 
    "isoforms": [
        {
            "url": "https://www.uniprot.org/uniprot/A2AJX4#A2AJX4-1", 
            "isoform_ac": "A2AJX4-1", 
            "locus": {
                "end_pos": 15526632, 
                "strand": "-", 
                "start_pos": 16255339, 
                "chromosome": "2", 
                "evidence": [
                    {
                        "url": "https://www.ensembl.org/id/ENSMUST00000146205", 
                        "id": "ENSMUST00000146205", 
                        "database": "Ensembl Transcript"
                    }, 
                    {
                        "url": "https://www.ensembl.org/id/ENSMUSP00000116869", 
                        "id": "ENSMUSP00000116869", 
                        "database": "Ensembl Peptide"
                    }
                ]
            }, 
            "sequence": {
                "header": "sp|A2AJX4-1|MALR1_MOUSE Isoform 1 of MAM and LDL-receptor class A domain-containing protein 1  OS=Mus musculus OX=10090 GN=Malrd1 PE=1 SV=2 CANONICAL=A2AJX4-1", 
                "length": 2123, 
                "sequence": "MFLPKAAVSAFSMHGSLCFLWTVCLSISPLSQQGVQAFQCSNGVSLPSDYVCDFTDHCGDNSEEQQCWSYGRCNFEDRLCSMTEDQTLQPGWTRRSGIISNSPPFWDHNGNISAHFLALVSRVDSISSNLRSRIFLPTNDQQVCQITFYNFSSNQNGKLIAGLQTLCGDPIEHLWQKTEILQSRWERNVITVQSSQQFQVIFQAQMLATHGQEEVIAIDDISFSSGCLPADVCQTCGFDLDTCGLATEASAGRTSWMCTKVREIPSLDSVPWQDQRGHDEGSFVWMRAGHASVSRLVESSAYLNSSVCHCMDGNCRLQFNYTMENSILRVRLYNDKEEKKTWTFNTSTYSTWMKADVLIPEDLKAFKVVLEGTVLSQKSFIGIDQLLVYNFGQTHSQKLCSVNEYTPASRQCLTHSSVCDSGMDHSNGIDEDSEACASLLTWDFESGFCGWEPFPTEDSHWEVVRGLSNGEHLFLEAGHTVSRNQGSFIYFGPQKSTAVARLGSPILTKSLTTFTPCQVRFWYHLSEHSSLSVFTRTSVDGSLLKQSEVTQFSDSQWSQAKVDLHAKAEESTLPFQLVLEATILSSNATVAVDDISISHECEISYKSLRSTSIQNKVADCDFEANSCGWFEASGGDHFDWVWSSQSNLSADLEQQAPPRDHTHGTAQGHFMFILKTSNSLFQTAKLQSPTFSQTGPGCTMSFWFYNYGLSVGAAELQLHLENSRDTTALWRVLYNQGNQWSEATVQLGRLTQPFYLSLEKVSLAVYSGVSAVDDIHFENCALPPPVESCDEPDHFWCRQTKACIGRHQLCDLVDDCGDYTDETGCAPGLQCNFENGICNWEQSTKDDFNWTRYQGPTSTMNTGPMKDHTLGTAKGHYLYIETSGPQGFQDKAVLLSPILNATEAKVCTFRLYYHMFGKHIYRLAIYQRIWSNTKGQLLWQIFGDQGNRWIRKDLSITSRKPFQILIMASVGDGFTGDIAIDDLSFMDCTLYPDNLPMDIPSPPETSVPVTLPPNNCTDDQFVCRSNGHCVGNIQKCDFRYDCIDKSDESSCVLEVCTFEERKLCKWYQPIPANSLHDSNTFRWGLGNGISIHHGEENHRPSVDHTKNTTDGWYLYADSSNGKFGDLADIVTPVISLMGPRCTLVFWTYMNGATVGSLQVLIKMGNTISKVWAQSGQQGPQWKKAEVFLGIHSHVEIVFRAKRGVSYIGDVAVDDVSFQNCSPLLSTNRKCTTDEFMCANKHCIEKDKLCDFVNDCADNSDETTFICGTSSGRCDFEFDLCTWEQDQDEDIDWNLKASNIPATSTEPAVDHTLGNSSGHYIILKSFFPQQPVKTGRISSPVISKRSKDCKIIFNYHMYGSGIAALLLLQVTVTNHTRVLLNLTKEQGNFWQRKELSLSSDEDFRVKFEGRVGEGIRGNIALDDIVLTKSCLPSHHSTREEPAFPLPTGFCPRGYEECQNGRCYSPEQRCNFVDDCGDNSDENECGGSCTFEKGWCGWKNSLAENSDWVLGIGSYKSQRPPKDHTLGNEHGHFMYLEATPVGLHGDKAHFKSATWQESSAACTMSFWYFISAKATGSIQILIKTDKGLWEVWQQSKPDPGNHWRRATILLGKLRNFEVIFQGIRTRDLGGGAAIDDIEFNNCTTVGETTDICSEETDFLCQDKKCIASHLVCDYKPDCSDTSDEAHCGYYTSTAGSCNFETTSGDWTVECGLTQDPEDDLDWSIGSIIPTEGLSRDSDHTPGSGRHFLYVNTSLAEEGSTARIITSHFFPASLGICTVRFWFYMVDPHIVGILKVYLIEKSGLNILMWSMMRNKNTGWTYAHVPLSSNSPFKVAFEADLGGKEDIFIALDDITFTPTCASGGPALPQPPLCEEGQFACIYALQCVSASEKCDGQEDCIDGSDEMNCSLGPSPQPCSDTEFQCFESQCIPSLLLCDGVADCQFNEDESSCVNQSCPSGALACNSSGLCIPAHQRCDGTAHCKDIQVDESSCSECPIHYCRNGGTCVIENIGPTCRCVQGWTGNRCHIRSNLSTEGSVHTQNYIWTLLGIGLGFLLTHIAVAILCSLGIRRRPMRKSEGVGNHSFINPVYRNCINQEKTQSSIYSFPNPFYGAASGSLETVSHHLKS"
            }
        }
    ], 
    "pathway": [
        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:102635496", 
            "resource": "KEGG Pathway", 
            "id": "mmu:102635496", 
            "name": ""
        }
    ], 
    "function": [
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297384.1", 
            "annotation": "Diet1 appears to be a control point for the production of fibroblast growth factor 15/19 in enterocytes, and thus a regulator of bile acid and lipid homeostasis.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297384.1", 
                    "id": "NP_001297384.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297384.1", 
            "annotation": "Diet1-deficient mice exhibited an elevated bile acid pool size and impaired feedback regulation of hepatic Cyp7a1, which encodes the rate-limiting enzyme in bile acid synthesis.", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297384.1", 
                    "id": "NP_001297384.1", 
                    "database": "RefSeq"
                }
            ]
        }, 
        {
            "url": "https://www.uniprot.org/uniprot/A2AJX4#function", 
            "annotation": "Enhances production and/or transport of FGF15 and thus has a role in regulation of bile acid synthesis.", 
            "evidence": [
                {
                    "url": "https://www.uniprot.org/uniprot/A2AJX4#function", 
                    "id": "A2AJX4", 
                    "database": "UniProtKB"
                }
            ]
        }, 
        {
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297384.1", 
            "annotation": "Genetic variation in DIET1 may be a determinant of FGF19 secretion levels, and may affect bile acid metabolism in both physiological and pathological conditions", 
            "evidence": [
                {
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297384.1", 
                    "id": "NP_001297384.1", 
                    "database": "RefSeq"
                }
            ]
        }
    ], 
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q5VYJ5-1", 
            "protein_name": "MAM and LDL-receptor class A domain-containing protein 1", 
            "sequence": {
                "length": 2156, 
                "sequence": "MLFFLDRMLAFPMNETFCCLWIACVFNSTLAQQGTESFQCDNGVSLPPDSICDFTDQCGDSSDERHCLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFYDHNGDVSAHFLSLVSRVDSISSSLRSRVFLPTNDQHDCQITFYYFSCQVSGKLMVGLQTACGGPIQHLWQNTAALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILLCQEALNAERELCHPDTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFESTPQQDQGGDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQFYYAMESSVLRVRLYNNKEEEIFWTYNISTHSQWVKADVLIPEDLKTFKIIFEGTLLSQRSFIALDHLWVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQDCSDESDEDPATCSKHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSPGVAKLGSPVLTKLLTASTPCQVQFWYHLSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIAEAGESTLPFQLILEATVLSSNATVALDDISVSQECEISYKSLPRTSTQSKFSKCDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSKNCKIIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKFEGRVGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLRPPKDHTLGNENGHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFVSAKATGSIQILIKTEKGLSKVWQESKQNPGNHWQKADILLGKLRNFEVIFQGIRTRDLGGGAAIDDIEFKNCTTVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRSDEAHCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDEMDCPLSPTPPLCSNMEFPCSTDECIPSLLLCDGVPDCHFNEDELICSNKSCSNGALVCASSNSCIPAHQRCDGFADCMDFQLDESSCSECPLNYCRNGGTCVVEKNGPMCRCRQGWKGNRCHIKFNPPATDFTYAQNNTWTLLGIGLAFLMTHITVAVLCFLANRKVPIRKTEGSGNCAFVNPVYGNWSNPEKTESSVYSFSNPLYGTTSGSLETLSHHLK"
            }, 
            "evidence": [
                {
                    "url": "http://www.informatics.jax.org/homology/136214", 
                    "id": "136214", 
                    "database": "MGI"
                }, 
                {
                    "url": "https://omabrowser.org/oma/group/A2AJX4/", 
                    "id": "A2AJX4", 
                    "database": "OMA"
                }
            ], 
            "common_name": "Human", 
            "organism": "Homo sapiens", 
            "tax_id": 9606
        }
    ], 
    "interactions": [], 
    "synthesized_glycans": [], 
    "snv": [], 
    "cluster_types": [
        {
            "name": "homologset.mgi", 
            "label": "MGI Homologs"
        }, 
        {
            "name": "homologset.oma", 
            "label": "OMA Homologs"
        }
    ], 
    "refseq": {
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001297384.1", 
        "ac": "NP_001297384.1", 
        "name": "MAM and LDL-receptor class A domain-containing protein 1 precursor", 
        "summary": ""
    }, 
    "go_annotation": {
        "categories": [
            {
                "go_terms": [
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", 
                        "pmid": "23747249", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AJX4", 
                                "id": "A2AJX4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "cytoplasm", 
                        "id": "GO:0005737"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AJX4", 
                                "id": "A2AJX4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "Golgi apparatus", 
                        "id": "GO:0005794"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016021", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AJX4", 
                                "id": "A2AJX4", 
                                "database": "UniProtKB"
                            }
                        ], 
                        "name": "integral component of membrane", 
                        "id": "GO:0016021"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", 
                        "pmid": "", 
                        "evidence": [
                            {
                                "url": "https://www.uniprot.org/uniprot/A2AJX4", 
                                "id": "A2AJX4", 
                                "database": "UniProtKB"
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                        "name": "cytoplasmic vesicle membrane", 
                        "id": "GO:0030659"
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                ], 
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                "name": "Cellular Component"
            }, 
            {
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                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042632", 
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                                "url": "https://www.uniprot.org/uniprot/A2AJX4", 
                                "id": "A2AJX4", 
                                "database": "UniProtKB"
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                        "name": "cholesterol homeostasis", 
                        "id": "GO:0042632"
                    }, 
                    {
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070858", 
                        "pmid": "23747249", 
                        "evidence": [
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                                "url": "https://www.uniprot.org/uniprot/A2AJX4", 
                                "id": "A2AJX4", 
                                "database": "UniProtKB"
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                        "name": "negative regulation of bile acid biosynthetic process", 
                        "id": "GO:0070858"
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                ], 
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            }
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            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000075520", 
            "id": "ENSMUSG00000075520", 
            "database": "Bgee"
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        {
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", 
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            "database": "CDD"
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        {
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        {
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        {
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            "id": "IPR000998", 
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        {
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        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013032", 
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        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", 
            "id": "IPR013320", 
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        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR023415", 
            "id": "IPR023415", 
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        }, 
        {
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", 
            "id": "IPR036055", 
            "database": "InterPro"
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        {
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:102635496", 
            "id": "mmu:102635496", 
            "database": "KEGG Pathway"
        }, 
        {
            "url": "http://www.informatics.jax.org/marker/MGI:1928271", 
            "id": "1928271", 
            "database": "MGI"
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        {
            "url": "https://omabrowser.org/oma/group/MWTDIAL/", 
            "id": "MWTDIAL", 
            "database": "OMA"
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        {
            "url": "http://www.orthodb.org/?query=72691at2759", 
            "id": "72691at2759", 
            "database": "OrthoDB"
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        {
            "url": "http://pfam.xfam.org/family/PF00057", 
            "id": "PF00057", 
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        {
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            "id": "PF00629", 
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        {
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            "database": "PRO"
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            "id": "NP_001297384.1", 
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            "position": 1749, 
            "glytoucan_ac": "", 
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        }
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    "disease": [], 
    "phosphorylation": [], 
    "mass": {
        "monoisotopic_mass": 236194.0, 
        "chemical_mass": 236194.0
    }, 
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        {
            "url": "https://www.uniprot.org/uniprot/A2AJX4", 
            "name": "Malrd1", 
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            "url": "https://www.ncbi.nlm.nih.gov/protein/A2AJX4", 
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            "url": "https://www.ncbi.nlm.nih.gov/protein/A2AJX4", 
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            "url": "https://www.uniprot.org/uniprot/A2AJX4", 
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            "resource": "UniProtKB", 
            "name": "MAM and LDL-receptor class A domain-containing protein 1"
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    ]
}